Wednesday, June 3, 2009 |
08:00:00 |
Conference registration and morning coffee |
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08:30:00 |
Opening remarks from the Chairperson |
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08:35:00 |
Conclusions from a review of ICH S7 guidelines |
Gerd Bode
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09:05:00 |
Overview of recent Q&A with E14 working group and the impacts for your future trial designs |
Charles T Benson
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09:35:00 |
Regulations Q&A |
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09:45:00 |
Effectively predicting QT prolongation in humans |
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10:20:00 |
Morning coffee |
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11:00:00 |
The translatability of existing and emerging preclinical cardiotoxicity assays |
Matthew J Killeen
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11:35:00 |
Stem cells as a tool in preclinical testing for QT prolongation |
Martin Traebert
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12:10:00 |
Spotlight session |
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12:45:00 |
Lunch |
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14:15:00 |
Bridging the gap between non-clinical and clinical studies |
Wilhelm Haverkamp
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14:50:00 |
Drug induced QT/QTc prolongation - Review of one-stage vs. two-stage methods to analyse clinical ECG data |
Jianguo Li
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15:25:00 |
Afternoon tea and high speed networking |
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16:05:00 |
Designing a tQT study for limited resources |
Arne Ring
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16:40:00 |
Methods for reducing variability in QT assessment |
Henry Holzgrefe
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17:15:00 |
Applications of mixed models in tQT studies |
Dennis Chanter
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17:50:00 |
Closing remarks from the Chairperson |
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17:55:00 |
End of day one |
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Thursday, June 4, 2009 |
08:30:00 |
Opening remarks from the Chairperson |
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08:35:00 |
Assessing the risk of proarrythmia? |
Danshi Li
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09:10:00 |
Three years post E14 guidance – Challenges and potential solutions |
Sasha Latypova
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09:45:00 |
Cardiac safety strategies for FIM studies for biopharmaceuticals |
Alexander Breidenbach
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10:20:00 |
Morning coffee and "meet the author" poster session |
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11:00:00 |
QT study design for oncology drugs |
Corina-Dana Dota,
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11:30:00 |
Unwanted QT problems in oncology programmes - A hERG trafficking case study |
Bérengère Dumotier
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12:00:00 |
Q&A session - What have we learned from oncology QT studies to date? |
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12:10:00 |
Spotlight session |
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12:45:00 |
Lunch |
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14:10:00 |
Drug related change in the ECG - A novel biomarker for cardiac risk? |
Christer Gottfridsson
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14:45:00 |
Optimized Holter extractions in tQT studies |
Fabio Badilini
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15:20:00 |
Afternoon tea |
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15:50:00 |
Increasing power through developing technologies - 12 lead ECG to continuous recording methods |
Corina-Dana Dota,
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16:25:00 |
Assessing the risk of Na channel inhibition |
Danshi Li
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17:00:00 |
Closing remarks from the Chairperson |
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17:10:00 |
End of conference |
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