Monday, April 6, 2009 |
07:00:00 |
Registration and Morning Coffee |
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08:00:00 |
Chairperson’s Opening Remarks |
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08:10:00 |
Keynote Presentation In Silico Fragment-Based Drug Design |
Eric Springman
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08:50:00 |
Fragment-Based Screening using Libraries in-silico and X-Ray Crystallography |
Kal Ramnarayan
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09:20:00 |
Virtual Fragment Linking: An Approach to Identify Potent Binders from Low Affi nity Fragment Hits |
Meir Glick
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09:50:00 |
Networking Coffee Break |
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10:15:00 |
Fragment-Based Drug Discovery - from Crystal to Clinic |
Gordon Saxty
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10:45:00 |
Recent Lessons in Fragment-Based Discovery |
Roderick Hubbard
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11:15:00 |
Bridging the Gap between Ligand- and Structure-Based Drug Design through the Application of Pharamophcores Derived from Fragment Docking |
Noeris Salam
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11:30:00 |
Fragment-Based Drug Discovery by NMR: Reaping the Benefi ts of Orthogonal Screening Approaches to Validate Hit Compounds Sponsored Presentation by Evotec |
Jan D. Kahmann
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12:00:00 |
Luncheon Presentation |
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13:00:00 |
Session Break |
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13:25:00 |
Chairperson’s Remarks |
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13:30:00 |
Fragment-Based Screening of Antibacterial Targets |
Igor Mochalkin
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14:00:00 |
Fragment Based Lead Design with Multiple Copy Simultaneous Search |
Shikha Varma-O’Brien
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14:30:00 |
Assessment of Additive/Non-Additive Effects in SAR: Implications in the Drug Discovery Iterative Process |
Julen Oyarzabal
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15:00:00 |
Sponsored Presentation (Opportunity Available) |
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15:15:00 |
Networking Refreshment Break in Exhibit Hall |
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16:00:00 |
Impact of Fragment Screening on the Rapid Discovery of Novel and Selective Protein Kinase Inhibitors |
Andreas Kuglstatter
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16:30:00 |
Panel Discussion: The Challenge of Turning Leads Into Results |
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17:30:00 |
Reception in the Exhibit Hall |
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18:30:00 |
End of day |
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Tuesday, April 7, 2009 |
08:00:00 |
Continental Breakfast Breakout Discussions |
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08:05:00 |
Topic 1: Fragment Library Screening |
Alex Burgin
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08:10:00 |
Topic 2: Fragment Based Drug Discovery Case Studies - What is the output in the last 10 years? |
Gordon Saxty
|
08:15:00 |
Topic 3: Computational Practices in Fragment-based Lead Design |
Shikha Varma-O’Brien
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08:20:00 |
Topic 4: Fragment-Based Drug Discovery - Are the Expectations being met? |
Roderick Hubbard
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09:00:00 |
Chairperson’s Remarks |
|
09:05:00 |
Fragment-Based Discovery of a Prolinol Derivative (DG-051) as a Novel Leukotriene A 4 Hydrolase Inhibitor for the Prevention of Myocardial Infarction |
Alex Kiselyov
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09:35:00 |
Effi cient Lead Discovery by Combining Structurally Related Fragment and Screening Libraries |
Daniel Obrecht
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10:05:00 |
Sponsored Presentation (Opportunity Available) |
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10:20:00 |
Networking Coffee Break in Exhibit Hall |
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11:00:00 |
Breakout Discussion Feedback by Moderators |
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11:30:00 |
An RNA-Directed Fragment Library |
Fareed Aboul-ela
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12:00:00 |
End of Conference |
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