Biotech China 2014
Growth factor receptor tyrosine kinases in mitogenesis, morphogenesis
Hilton Tucson El Conquistador
10000 N, Oracle Rd, Tucson, AZ 85704
mm, mm
http://src.faseb.org
1. Growth factor RTKs: interactions in 
development and morphogenesis 2.Receptors and ligands in tumor 
progression, invasion and metastasis 
3.Signal activation, imaging and quantitation 4.Signaling specificity of growth factor 
RTKs (1st part) 
5.Selected Talks from Poster Sessions 6.Signaling specificity of growth factor 
RTKs (2nd part)7.Therapeutic targeting of growth factor 
RTKs 8.Activation and inactivation of tyrosine 
kinases 9.RTKs in development, migration and 
lower organisms.




Schedule of Presentations:

Saturday, August 11, 2007
16:00:00 Conference Registration
18:00:00 FASEB Opening Reception
19:00:00 Dinner
Sunday, August 12, 2007
07:30:00 Breakfast
09:00:00 Morning Free
12:00:00 Lunch
13:00:00 Actin nucleation complexes and Abl tyrosine kinases in the regulation of morphogenesis and intercellular adhesion Ann M Pendergast
13:35:00 Bi-directional eph/ephrin signaling in axon guidance Rüdiger Klein
14:10:00 Group photo and FASEB Sponsored Coffee Break
14:50:00 EphA receptors in neuron-glia communication Elena Pasquale
15:25:00 The Met receptor is essential for wound healing in the skin Walter Birchmeier
16:00:00 Poster Session
18:00:00 Dinner
19:00:00 Receptors and ligands in tumor progression, invasion and metastasis Carmen Birchmeier
19:00:00 Proliferation, invasion, genetic instability and malignant progression George F Vande Woude
19:35:00 Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation David D Schlaepfer
20:10:00 Break
20:25:00 Role of Src/FAK interactions in cancer Margaret Frame
21:00:00 Ras family GTPases, through independent effectors, cooperate in the activation of the Raf-MAPK pathway Pablo Viciana Rodriguez
21:35:00 Questions and Discussion
Monday, August 13, 2007
07:30:00 Breakfast
09:00:00 Morning Free
12:00:00 Lunch
13:00:00 Morphogenesis and oncogenesis in 3D breast epithelial cell cultures Joan Brugge
13:00:00 Signal activation, imaging and quantitation Benjamin G Neel
13:35:00 Visualizing the mechanical activation of Src Shu Chien
14:10:00 FASEB Sponsored Coffee Break
14:30:00 Quantitative proteomic analysis of cellular signaling networks Forest White
15:05:00 Visualizing RhoC and VEGF-mediated cancer cell invasion in optically transparent zebrafish Richard Klemke
15:40:00 Questions and Discussion
16:00:00 Poster Session
18:00:00 Dinner
19:00:00 Signaling specificity of growth factor RTKs (1st part) Nancy E Hynes
19:00:00 Cell signaling by receptor tyrosine kinases: from bench to bedside Joseph Schlessinger
19:35:00 Met receptor tyrosine kinase: intracellular trafficking, stability and transformation Morag Park
20:10:00 Break
20:25:00 Ubiquitin networks in EGFR signaling Ivan Dikic
21:00:00 Structural basis for recruitment of positive and negative regulators to the insulin receptor Steve Hubbard
21:35:00 Questions and Discussion
Tuesday, August 14, 2007
07:30:00 Breakfast
09:00:00 Morning Free
12:00:00 Lunch
13:00:00 Selected Talks from Poster Sessions David Stern,
13:00:00 Utilization of IGF-IR transgenic mice to understand tumor initiation, progression and IGF-IR independence Roger A Moorehead
13:20:00 The role of CE44v6 as a co-receptor for c-Met Véronique Orian Rousseau
13:40:00 Memo regulates ErbB2-driven microtubule dynamics and formation of adhesion sites Ali Badache
14:00:00 The tyrosine phosphatase Shp2 is a regulator of peripheral glia development and myelination Katja S Grossmann,
14:20:00 FASEB Sponsored Coffee Break
14:50:00 Cancer-causing mutations in PDGFR-alpha can be disruptive to mouse development Lorin E Olson
15:10:00 Regulating epidermal growth factor receptor during breast cancer progression Joyce A Schroeder
15:30:00 Antibodies which specifically recognize over-expressed, mutated or activated forms of the EGFR on tumor cells bind to an epitope that is unmasked during the transition form the tethered to the untethered conformation Terrance G Johns
15:50:00 Questions and Discussion
16:00:00 Poster Session
18:00:00 Dinner
19:00:00 RTK induced signaling pathways in breast cancer growth and metastasis Nancy E Hynes
19:00:00 Signaling specificity of growth factor RTKs (2nd part) Mark Sliwkowski
19:35:00 Trafficking of ErbB receptors to the nucleus Graham F Carpenter
20:10:00 Break
20:25:00 Nuclear role for the EGFR and ERBB2 Mien-Chie Hung
21:00:00 FGF receptors and cancer François Radvanyi
21:35:00 Questions and Discussion
Wednesday, August 15, 2007
07:30:00 Breakfast
09:00:00 Free Morning/Organized Activities
12:00:00 Lunch
13:00:00 Targeting the mTOR kinase in human cancer Heidi A Lane
13:00:00 Therapeutic targeting of growth factor RTKs Morag Park
13:35:00 HER2 activation in breast and ovarian cancers Mark Sliwkowski
14:10:00 FASEB Sponsored Coffee Break
14:30:00 Defining novel cancer therapy targets Bernd Groner
15:05:00 Targeting PDGF receptors in cancer Carl-Henrik Heldin
15:40:00 Questions and Discussion
16:00:00 Poster Session
18:00:00 Dinner
19:00:00 Shp2 in health and disease Benjamin G Neel
19:00:00 Activation and inactivation of tyrosine kinases Daniel J Leahy
19:35:00 Interactions between hedgehog and the Ihog/CDO family of co-receptors are fundamentally different in vertebrates and invertebrates Daniel J Leahy
20:10:00 Break
20:25:00 Fak regulation William Muller
21:35:00 Questions and Discussion
Thursday, August 16, 2007
07:30:00 Breakfast
09:00:00 The control of growth factor signalling by rhomboid proteases Matthew Freeman
09:00:00 RTKs in development, migration and lower organisms William Muller
09:35:00 Lateral inhibition of EGFR signaling during C. elegans vulval development: only one can be first Alex Hajnal
10:10:00 FASEB Sponsored Coffee Break
10:25:00 The tyrosine phosphatase Shp2 (Ptp11) mediates essential Nrg1/ErbB signals during Schwann cell development Carmen Birchmeier
11:00:00 ErbBs in mammary development and breast Cancer David Stern,
11:35:00 Box Lunches Available
12:30:00 END OF CONFERENCE
4th Annual Pharma R&D Asia Congress
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