| Saturday, August 11, 2007 |
| 16:00:00 |
Conference Registration |
|
| 18:00:00 |
FASEB Opening Reception |
|
| 19:00:00 |
Dinner |
|
| Sunday, August 12, 2007 |
| 07:30:00 |
Breakfast |
|
| 09:00:00 |
Morning Free |
|
| 12:00:00 |
Lunch |
|
| 13:00:00 |
Actin nucleation complexes and Abl tyrosine kinases in the regulation of morphogenesis and intercellular adhesion |
Ann M Pendergast
|
| 13:35:00 |
Bi-directional eph/ephrin signaling in axon guidance |
Rüdiger Klein
|
| 14:10:00 |
Group photo and FASEB Sponsored Coffee Break |
|
| 14:50:00 |
EphA receptors in neuron-glia communication |
Elena Pasquale
|
| 15:25:00 |
The Met receptor is essential for wound healing in the skin |
Walter Birchmeier
|
| 16:00:00 |
Poster Session |
|
| 18:00:00 |
Dinner |
|
| 19:00:00 |
Proliferation, invasion, genetic instability and malignant progression |
George F Vande Woude
|
| 19:00:00 |
Receptors and ligands in tumor progression, invasion and metastasis |
Carmen Birchmeier
|
| 19:35:00 |
Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation |
David D Schlaepfer
|
| 20:10:00 |
Break |
|
| 20:25:00 |
Role of Src/FAK interactions in cancer |
Margaret Frame
|
| 21:00:00 |
Ras family GTPases, through independent effectors, cooperate in the activation of the Raf-MAPK pathway |
Pablo Viciana Rodriguez
|
| 21:35:00 |
Questions and Discussion |
|
| Monday, August 13, 2007 |
| 07:30:00 |
Breakfast |
|
| 09:00:00 |
Morning Free |
|
| 12:00:00 |
Lunch |
|
| 13:00:00 |
Morphogenesis and oncogenesis in 3D breast epithelial cell cultures |
Joan Brugge
|
| 13:00:00 |
Signal activation, imaging and quantitation |
Benjamin G Neel
|
| 13:35:00 |
Visualizing the mechanical activation of Src |
Shu Chien
|
| 14:10:00 |
FASEB Sponsored Coffee Break |
|
| 14:30:00 |
Quantitative proteomic analysis of cellular signaling networks |
Forest White
|
| 15:05:00 |
Visualizing RhoC and VEGF-mediated cancer cell invasion in optically transparent zebrafish |
Richard Klemke
|
| 15:40:00 |
Questions and Discussion |
|
| 16:00:00 |
Poster Session |
|
| 18:00:00 |
Dinner |
|
| 19:00:00 |
Cell signaling by receptor tyrosine kinases: from bench to bedside |
Joseph Schlessinger
|
| 19:00:00 |
Signaling specificity of growth factor RTKs (1st part) |
Nancy E Hynes
|
| 19:35:00 |
Met receptor tyrosine kinase: intracellular trafficking, stability and transformation |
Morag Park
|
| 20:10:00 |
Break |
|
| 20:25:00 |
Ubiquitin networks in EGFR signaling |
Ivan Dikic
|
| 21:00:00 |
Structural basis for recruitment of positive and negative regulators to the insulin receptor |
Steve Hubbard
|
| 21:35:00 |
Questions and Discussion |
|
| Tuesday, August 14, 2007 |
| 07:30:00 |
Breakfast |
|
| 09:00:00 |
Morning Free |
|
| 12:00:00 |
Lunch |
|
| 13:00:00 |
Utilization of IGF-IR transgenic mice to understand tumor initiation, progression and IGF-IR independence |
Roger A Moorehead
|
| 13:00:00 |
Selected Talks from Poster Sessions |
David Stern,
|
| 13:20:00 |
The role of CE44v6 as a co-receptor for c-Met |
Véronique Orian Rousseau
|
| 13:40:00 |
Memo regulates ErbB2-driven microtubule dynamics and formation of adhesion sites |
Ali Badache
|
| 14:00:00 |
The tyrosine phosphatase Shp2 is a regulator of peripheral glia development and myelination |
Katja S Grossmann,
|
| 14:20:00 |
FASEB Sponsored Coffee Break |
|
| 14:50:00 |
Cancer-causing mutations in PDGFR-alpha can be disruptive to mouse development |
Lorin E Olson
|
| 15:10:00 |
Regulating epidermal growth factor receptor during breast cancer progression |
Joyce A Schroeder
|
| 15:30:00 |
Antibodies which specifically recognize over-expressed, mutated or activated forms of the EGFR on tumor cells bind to an epitope that is unmasked during the transition form the tethered to the untethered conformation |
Terrance G Johns
|
| 15:50:00 |
Questions and Discussion |
|
| 16:00:00 |
Poster Session |
|
| 18:00:00 |
Dinner |
|
| 19:00:00 |
Signaling specificity of growth factor RTKs (2nd part) |
Mark Sliwkowski
|
| 19:00:00 |
RTK induced signaling pathways in breast cancer growth and metastasis |
Nancy E Hynes
|
| 19:35:00 |
Trafficking of ErbB receptors to the nucleus |
Graham F Carpenter
|
| 20:10:00 |
Break |
|
| 20:25:00 |
Nuclear role for the EGFR and ERBB2 |
Mien-Chie Hung
|
| 21:00:00 |
FGF receptors and cancer |
François Radvanyi
|
| 21:35:00 |
Questions and Discussion |
|
| Wednesday, August 15, 2007 |
| 07:30:00 |
Breakfast |
|
| 09:00:00 |
Free Morning/Organized Activities |
|
| 12:00:00 |
Lunch |
|
| 13:00:00 |
Therapeutic targeting of growth factor RTKs |
Morag Park
|
| 13:00:00 |
Targeting the mTOR kinase in human cancer |
Heidi A Lane
|
| 13:35:00 |
HER2 activation in breast and ovarian cancers |
Mark Sliwkowski
|
| 14:10:00 |
FASEB Sponsored Coffee Break |
|
| 14:30:00 |
Defining novel cancer therapy targets |
Bernd Groner
|
| 15:05:00 |
Targeting PDGF receptors in cancer |
Carl-Henrik Heldin
|
| 15:40:00 |
Questions and Discussion |
|
| 16:00:00 |
Poster Session |
|
| 18:00:00 |
Dinner |
|
| 19:00:00 |
Shp2 in health and disease |
Benjamin G Neel
|
| 19:00:00 |
Activation and inactivation of tyrosine kinases |
Daniel J Leahy
|
| 19:35:00 |
Interactions between hedgehog and the Ihog/CDO family of co-receptors are fundamentally different in vertebrates and invertebrates |
Daniel J Leahy
|
| 20:10:00 |
Break |
|
| 20:25:00 |
Fak regulation |
William Muller
|
| 21:35:00 |
Questions and Discussion |
|
| Thursday, August 16, 2007 |
| 07:30:00 |
Breakfast |
|
| 09:00:00 |
RTKs in development, migration and lower organisms |
William Muller
|
| 09:00:00 |
The control of growth factor signalling by rhomboid proteases |
Matthew Freeman
|
| 09:35:00 |
Lateral inhibition of EGFR signaling during C. elegans vulval development: only one can be first |
Alex Hajnal
|
| 10:10:00 |
FASEB Sponsored Coffee Break |
|
| 10:25:00 |
The tyrosine phosphatase Shp2 (Ptp11) mediates essential Nrg1/ErbB signals during Schwann cell development |
Carmen Birchmeier
|
| 11:00:00 |
ErbBs in mammary development and breast Cancer |
David Stern,
|
| 11:35:00 |
Box Lunches Available |
|
| 12:30:00 |
END OF CONFERENCE |
|
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