| Wednesday, August 5, 2009 | ||
| 07:30:00 | Registration and Coffee | |
| 08:30:00 | Conference Chair Opening Remarks | Ulrik B Nielsen |
| 08:35:00 | Opening Address | |
| 08:40:00 | Linking Targets to Disease: Lessons Learned and Future Directions | Anuk Das |
| 08:45:00 | Genomics, Proteomics and Systems Biology Approaches to Finding the Right Target | |
| 09:05:00 | Quantitative Proteomics/Metabolomics is a Tool for Investigating Drug Targets and Biological Phenomena | Yoshiya Oda |
| 09:30:00 | Using Biomarkers to Link Druggable Nodes to Clinically Relevant Pathways | Stephen Horrigan |
| 09:55:00 | Human Genetics and Disease Relevant Targets: Linking Clinical Outcomes to Targets | Albert B. Seymour |
| 10:20:00 | Networking Refreshment Break in Exhibit & Poster Hall | |
| 11:00:00 | Applied Systems Biology for Drug Response Profiling | Ariel A. Cohen |
| 11:25:00 | Systems Biology of Receptor Kinase Signaling in Drosophila - A Reliable and Quick Reference for Translational Research | Srinivasan Krishnamoorthy |
| 11:50:00 | Confirmation of JNJ-38877605 as a selective c-Met kinase inhibitor using quantitative chemical proteomics. | Tim Perera |
| 12:15:00 | Networking Luncheon in Exhibit & Poster Hall | |
| 12:20:00 | In Vivo and Computational Approaches | |
| 14:00:00 | Understanding Disease Neurobiology to Generate Predictive Translational Models | John H. Kehne |
| 14:25:00 | An Attempt to Translate In Vitro Responses into the Clinic Using Computationally Predicted Preclinical Data from ErbB Targeted Therapies | Birgit Schoeberl |
| 14:50:00 | Computational Elucidation of Signaling Pathway Alterations in Disease States | Karen Sachs |
| 14:55:00 | Conference Keynote | |
| 15:15:00 | Michael Foley, Ph.D. Build-Couple-Pair Strategy for Diversity-Oriented Synthesis Yields a Unique Compound Collection for Probe Development and Drug Discovery | Michael Foley |
| 15:45:00 | Networking Refreshment Break in Exhibit & Poster Hall | |
| 15:50:00 | RNAi Approaches To Target Validation | |
| 16:50:00 | Genome-Wide High-Content siRNA Screens Reveal Challenges and Limitations of Current siRNA Technology | Eberhard Krausz |
| 16:55:00 | Focused siRNA Screens in Disease Based Assays: The Fast Track to a Target | Alex Gaither |
| 17:20:00 | Close of Day One | |
| 18:00:00 | Attendee Networking Dinner in Boston | |
| 18:05:00 | Announcements | |
| 18:10:00 | Preparation for next day | |
| Thursday, August 6, 2009 | ||
| 08:40:00 | Conference Chair Opening Remarks | Michael D. Winther |
| 08:40:00 | High Content / High Throughput Screening & Assay Approaches | |
| 08:45:00 | Ligands of Orphan GPCRs Identified from Inducible Expression of the Receptors and Cell-based Reporter Screen | Paul Lee |
| 09:10:00 | Comparison of Whole-Cell, Label-Free Assays for GPCR Drug Discovery | Matthew Peters |
| 09:35:00 | In Vivo Chemical Screening in Zebrafish | Joanna Yeh |
| 10:00:00 | Label-Free Detection of Chemotactic and Other GPCR Responses Using EPIC Technology | Marc Lamphier |
| 10:30:00 | Networking Refreshment Break | |
| 11:00:00 | Capturing the Complexity of Cellular Systems | John K. Westwick |
| 11:25:00 | Tissue Engineered Tumor Niches as Drug Testing Platforms | Eric YH Park |
| 11:30:00 | Technology Workshop | |
| 11:50:00 | Technology Presentation - Available for Sponsorship | |
| 12:15:00 | Networking Luncheon with Attendee/Speaker Chat Sessions | |
| 12:20:00 | Discussion topics include: | |
| 12:25:00 | # Getting The Most Out Of Your Images - Current Tools and Limitations, and Future Development | |
| 12:35:00 | # Safety & Toxicity Assay Challenges and Advances | |
| 12:40:00 | # Trends Towards In Vitro and In Silico Models | |
| 12:50:00 | # Label-Free Assays - Applications and Limitations | |
| 13:00:00 | RNAi in Practice Ð Assays and Screening in Mammalian Cells | Steven Haney |
| 13:15:00 | Case Studies to Illustrate Preclinical To Clinical Translation - Ensuring the Ultimate Clinical Success Of Your Targets | |
| 14:00:00 | Innovation by Novel and Established Drug Targets | Khusru Asadullah |
| 14:25:00 | Novel Small Molecule Sirtuin 1 Activators for the Treatment of Metabolic Disease and Diseases of Aging | James L. Ellis |
| 14:50:00 | Modifying Lipid Biosynthesis to Treat Diabesity | Michael D. Winther |
| 15:15:00 | Networking Refreshment Break | |
| 15:45:00 | INK128 - A novel and highly selective mTORC1 and mTORC2 Kinase Inhibitor | Yi Liu |
| 16:15:00 | Dissecting the Molecular Mediators of Inflammation-Induced Urinary Bladder Overactivity | Kevin S. Thorneloe |
| 16:45:00 | Close of Conference | |
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