Biotech China 2014
Cambridge Healthtech Institute's Third Annual Mastering Process Chemistry Oct (15-17)
Park Hyatt Philadelphia
200 South Broad Street
Philadelphia, PA
http://www.healthtech.com/2007/psu/sponsor.asp
Cambridge Healthtech Institute's Third Annual Mastering Process Chemistry 
optimizing pharmaceutical development

Schedule of Presentations:

Monday, October 15, 2007
07:30:00 PRE-CONFERENCE SHORT COURSE: Pre-Conference Short Course Registration (07:30-08:30) Neal G. Anderson
07:30:00 PRE-CONFERENCE SHORT COURSE: DEMYSTIFYING PROCESS CHEMISTRY (07:30-12:30) Neal G. Anderson
08:30:00 PRE-CONFERENCE SHORT COURSE: Welcome by Short Course Instructor (08:30-08:40) Neal G. Anderson
08:40:00 PRE-CONFERENCE SHORT COURSE: Currents of Green Chemistry Underlying Cost-Effective Process Developmentr (08:40-09:20) Neal G. Anderson
09:20:00 PRE-CONFERENCE SHORT COURSE: Route Selection Goals (09:20-10:00) Neal G. Anderson
10:00:00 PRE-CONFERENCE SHORT COURSE: Optimizing Process Development by Minimizing Impurities (10:00-10:40) Neal G. Anderson
10:40:00 PRE-CONFERENCE SHORT COURSE: Networking Coffee Break (10:40-11:10)
11:10:00 PRE-CONFERENCE SHORT COURSE: Developing Selective Crystallizations (11:10-11:50) Neal G. Anderson
11:50:00 PRE-CONFERENCE SHORT COURSE: Process Refinements (11:50-12:30) Neal G. Anderson
12:30:00 Close of Pre-Conference Short Course
12:30:00 Main Conference Registration (12:30-13:30)
13:30:00 CASE STUDIES OF PRACTICAL SYNTHESIS (13:30-18:30) Case Studies Oliver Thiel, Cheng-yi Chen, Roger P. Bakale, Shu Yu, Matt Weekly
13:30:00 CASE STUDIES OF PRACTICAL SYNTHESIS: Chairperson’s Welcoming Remarks (13:30-13:40)
13:40:00 CASE STUDIES OF PRACTICAL SYNTHESIS: Process Development and Scale-Up of AG035029, a Potent PPARg Agonist for Treatment of Type II Diabetes (13:40-14:10) Shu Yu
14:10:00 CASE STUDIES OF PRACTICAL SYNTHESIS: Practical Synthesis of TRPV1 Antagonists for Treatment of Pain (14:10-14:40) Oliver Thiel
14:40:00 CASE STUDIES OF PRACTICAL SYNTHESIS: Catalytic, Enantioselective Synthesis of Taranabant, a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist for the Treatment of Obesity (14:40-15:10) Cheng-yi Chen
15:10:00 CASE STUDIES OF PRACTICAL SYNTHESIS: Networking Refreshment Break, Poster and Exhibit Viewing (15:10-15:40)
15:40:00 CASE STUDIES OF PRACTICAL SYNTHESIS: Identification and Development of Efficient Process Methodology: Case Studies on Selective Monoamine Reuptake Inhibitors (15:40-16:10) Roger P. Bakale
16:10:00 CASE STUDIES OF PRACTICAL SYNTHESIS: From First Bulk to a Commercial Route: Evolution of the Torcetrapib Process (16:10-16:40) Matt Weekly
16:40:00 CASE STUDIES OF PRACTICAL SYNTHESIS: Questions and Answers (16:40-17:00)
17:00:00 CASE STUDIES OF PRACTICAL SYNTHESIS: Networking Reception in the Exhibit Hall (17:00-18:30)
18:30:00 Close of Day One
Tuesday, October 16, 2007
08:40:00 Interactive Roundtable Discussions; Threats and Opportunities for Process Development #1: Converting Process Development Difficulties (Threat) to Opportunities for Process Optimization (08:40-09:40) Neal G. Anderson
08:40:00 Interactive Roundtable Discussions: Threats and Opportunities for Process Development (08:40-09:40) Roger P. Bakale, Chris Davis, Neal G. Anderson, Quirinus B. Broxterman
08:40:00 Interactive Roundtable Discussions; Threats and Opportunities for Process Development #2: Meeting the Challenges of Outsourcing Difficult Chemistries (08:40-09:40) Roger P. Bakale
08:40:00 Interactive Roundtable Discussions; Threats and Opportunities for Process Development #3: The Need to Introduce Superior New Synthetic Technologies (Opportunity) vs. Project Dynamics that Suggest Waiting (Until It Is Too Late?) (Threat) (08:40-09:40) Quirinus B. Broxterman
08:40:00 Interactive Roundtable Discussions; Threats and Opportunities for Process Development #4: Green Chemistry: Threat or Opportunity? (08:40-09:40) Chris Davis
09:40:00 STRATEGIZING FOR COMMERCIAL SUCCESS (09:40-12:30) David Mitchell, Quirinus B. Broxterman, Neal G. Anderson, Joseph D'Antuono
09:40:00 STRATEGIZING FOR COMMERCIAL SUCCESS: Chairperson’s Remarks (09:40-09:45)
09:45:00 STRATEGIZING FOR COMMERCIAL SUCCESS: Title to Be Announced (09:45-10:15) Joseph D'Antuono
10:15:00 STRATEGIZING FOR COMMERCIAL SUCCESS: Cost-Efficient Deprotection of PMP: Toward an Industrially Viable Asymmetric Mannich Protocol (10:15-10:45) Quirinus B. Broxterman
10:45:00 STRATEGIZING FOR COMMERCIAL SUCCESS: Networking Coffee Break, Poster and Exhibit Viewing (10:45-11:30)
11:30:00 STRATEGIZING FOR COMMERCIAL SUCCESS: Case Study of Outsourcing Process Chemistry (11:30-12:00) Case Study David Mitchell
12:00:00 STRATEGIZING FOR COMMERCIAL SUCCESS: Process Validation from the Standpoint of an Organic Chemist (12:00-12:30) Neal G. Anderson
12:30:00 Lunch on Your Own or Luncheon Technology Workshops (12:30-14:00)
14:00:00 PROCESS OPTIMIZATION VIA ANALYTICS (14:00-15:05) Michael Breslav, Amit Banerjee, Frans L. Muller, Mel Koch
14:00:00 PROCESS OPTIMIZATION VIA ANALYTICS: Chairperson's Remarks (14:00-14:05)
14:05:00 PROCESS OPTIMIZATION VIA ANALYTICS: Spotlight on Biologics Process Development: Challenges in mAb Production and Application of PAT (14:05-14:50) Amit Banerjee
14:50:00 PROCESS OPTIMIZATION VIA ANALYTICS: An Overview of Micro-technology in Process Analytics (14:50-15:35) Mel Koch
15:35:00 PROCESS OPTIMIZATION VIA ANALYTICS: Networking Refreshment Break, Poster and Exhibit Viewing (15:35-16:05)
16:05:00 PROCESS OPTIMIZATION VIA ANALYTICS: Isolation of the Drug Substance Impurities at 0.05–0.1% Level Using At-Column Dilution, Mass-Driven Collection, and Comprehensive Automation of the Entire Process (16:05-16:35) Michael Breslav
16:35:00 PROCESS OPTIMIZATION VIA ANALYTICS: Anticipation of Scale-Up Issues in Process Development: Scale Up Risk Evaluation (SURE) (16:35-17:05) Frans L. Muller
17:05:00 Close of Day Two
Wednesday, October 17, 2007
08:55:00 BIOCATALYSIS FOR CHEMICAL PROCESS DEVELOPMENT: Chairperson’s Remarks (08:55-09:00)
08:55:00 BIOCATALYSIS FOR CHEMICAL PROCESS DEVELOPMENT (08:55-12:00) Paul N. Devine, John C. Warner, David Mitchell, Chris Davis, Mel Koch, Junhua Tao
09:00:00 BIOCATALYSIS FOR CHEMICAL PROCESS DEVELOPMENT: Biocatalysis in Process Research (09:00-09:30) Paul N. Devine
09:30:00 BIOCATALYSIS FOR CHEMICAL PROCESS DEVELOPMENT: Green Manufacture of Chiral Alcohols Using Custom-Evolved Biocatalysts – Replacing Boron-Based Reducing Agents (09:30-10:00) Chris Davis
10:00:00 BIOCATALYSIS FOR CHEMICAL PROCESS DEVELOPMENT: Biocatalysis for Green Chemistry and Chemical Process Development (10:00-10:20) Junhua Tao
10:20:00 BIOCATALYSIS FOR CHEMICAL PROCESS DEVELOPMENT: Networking Coffee Break (10:20-11:00)
11:00:00 BIOCATALYSIS FOR CHEMICAL PROCESS DEVELOPMENT: Moderated Panel Discussion (11:00-12:00) Junhua Tao, Mel Koch, David Mitchell, John C. Warner
12:00:00 Lunch on Your Own or Luncheon Technology Workshops (12:00-13:30)
13:30:00 GREEN CHEMISTRY SPOTLIGHT: Chairperson's Remarks (13:30-13:35)
13:30:00 GREEN CHEMISTRY SPOTLIGHT (13:30-14:35) Rajender S. Varma, John C. Warner
13:35:00 GREEN CHEMISTRY SPOTLIGHT: Green Chemistry ; Process Improvements through Mechanistic Design (13:35-14:05) John C. Warner
14:05:00 GREEN CHEMISTRY SPOTLIGHT: Greener Chemical Synthetic Approaches to Heterocycles, Noble Nanometals, and Nanocomposites (14:05-14:35) Rajender S. Varma
14:35:00 NOVEL IMPROVEMENTS FOR OPTIMAL SYNTHESIS: A Mild Version of Grignard Reagents and Its Application for the Production of Drug Substances(14:35-15:05) Xiao-jun Wang
14:35:00 NOVEL IMPROVEMENTS FOR OPTIMAL SYNTHESIS(14:35-16:00) Xiao-jun Wang, Charles E. Chase
15:05:00 NOVEL IMPROVEMENTS FOR OPTIMAL SYNTHESIS: Process Research on the Halichondrin B Analog Eribulin: A New Route to C.14-C.26 (15:05-15:35) Charles E. Chase
15:35:00 NOVEL IMPROVEMENTS FOR OPTIMAL SYNTHESIS: Questions and Answers (15:35-16:00)
16:00:00 Close of Conference
4th Annual Pharma R&D Asia Congress
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