Health China
Engineering Antibodies
Sheraton Boston Hotel

Boston, Massachusetts


   Therapeutic and diagnostic antibodies continue to make in inroads in
   biomedicine, but the successful application of these products requires
   smart discovery and development. This conference will explore the
   latest methods to overcome challenges and open new opportunities for
   making these valuable proteins viable.

Schedule of Presentations:

Wednesday, May 19, 2010
07:00:00 Registration and Morning Coffee
08:25:00 DISCOVERY
08:30:00 Chairperson’s Opening Remarks George Georgiou
08:40:00 Unique Combination of Computational Modeling, Antibody Engineering and Cell Biology Birgit Schoeberl
09:10:00 Importance of Early and Complete Characterization of Antibodies in the Lead Selection Process Shrikant Deshpande
09:40:00 Case Study: Engineered Human Antibody CH2 Constant Domains (Nanoantibodies) as Novel Candidate Therapeutics Rui Gong
10:10:00 Coffee Break, Poster and Exhibit Viewing
11:10:00 A Computational-Experimental Strategy for the Isolation of Antigen-Specific Antibodies from Immunized Animals George Georgiou
11:40:00 Analytical Methods to Characterize and Evaluate the Mode of Action of Antibody Drug Conjugates Vangipuram Rangan
12:10:00 Luncheon Presentation I - Slonomics® - An Innovative Toolbox for the Precise Engineering of Immunoglobulin Repertoires Thomas Waldmann
12:40:00 Luncheon Presentation II (Opportunity Available)
13:30:00 Chairperson’s Remarks
13:35:00 Application of H/D-Exchange for Epitope Screening to Assist with Candidate mAb Selection Jennifer Nemeth
14:05:00 A Multi-Fc-Species System for Recombinant Antibody Production Stefan Dübel
14:35:00 Use of Disposable Label-Free Real-Time Biosensors in Epitope Binning Monoclonal Antibodies Yasmina Abdiche
14:50:00 Deriving and Epitope Mapping | Antibodies Targeting Membrane Proteins Benjamin Doranz
15:15:00 Networking Refreshment Break, Poster and Exhibit Viewing
15:50:00 Problem Solving Break-Out Sessions
16:00:00 In vitro screening or immunization? Isolating biologically active antibodies George Georgiou
16:10:00 CMC issues with ADCs Vangipuram Rangan
16:20:00 Engineered Antibody Domains Rui Gong
16:30:00 Increasing Efficiency of Phage Display Libraries and Selection Stefan Dübel
16:40:00 Stability prediction parameters: How well they perform in the real world? Shrikant Deshpande
16:50:00 Networking Cocktail Reception in the Exhibit Hall
18:00:00 End of Day
Thursday, May 20, 2010
08:00:00 Registration and Morning Coffee
08:30:00 Chairperson’s Opening Remarks Stefan Dübel
08:35:00 Structure-Based Prediction of Antibody Epitopes Julia Ponomarenko
09:05:00 A Novel Approach to Antibody Drug Conjugates James Prudent
09:35:00 A Paradigm Shift in Protein Expression Enabling Lead Selection Concomitant with Isolation of the Production Cell Line Pierre Girod
10:05:00 Coffee Break, Poster and Exhibit Viewing
11:05:00 DARPins as Alternative to Antibodies Michael T. Stumpp
11:35:00 Fc N-linked Oligosaccharides and their Effect on Recombinant IgG1 Monoclonal Antibody Binding to Protein-A and Protein-G Georgeen Gaza-Bulseco
12:05:00 End of Conference
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