BSN: Antibody Optimization

   Speakers
   --------

   N/A

   The second stage of antibody drug or diagnostic development can
   sometimes be the most difficult-the optimization. This conference will
   present methods researchers can apply to make their antibody the best,
   most functional and least immunogenic it can be.

Event Sponsors

Cambridge Healthtech Associates

Schedule of Presentations:

Thursday, May 20, 2010
12:00:00	Registration
13:25:00	TARGETING, SPECIFICITY AND AFFINITY
13:30:00	Chairperson’s Opening Remarks
13:40:00	Conferring Meaningful Anti-Tumor Activity to Monoclonal Antibodies by Linking Cell Killing Agents	Ravi V. Chari
14:10:00	Recombinant Human Multi-Domain Fusion Proteins	Stefan Barth
14:40:00	Design and Produce Better Antibodies with Antigen Profiler	Matt Baker
15:10:00	Networking Refreshment Break, Poster and Exhibit Viewing
16:00:00	Optimizing Antibody Homogeneity and Development: Lessons Learned from Structural and Functional Studies	Alain Beck
16:30:00	Antibody-Drug Conjugates to Improve Therapeutic Index	Wei Liao
17:00:00	End of Day
Friday, May 21, 2010
07:45:00	Continental Breakfast in the Exhibit Hall
08:25:00	HALF-LIFE, SENSITIVITY AND EFFICACY
08:30:00	Chairperson’s Opening Remarks	Gerald Casperson
08:35:00	Trastuzumab Conjugate for the Treatment of Trastuzumab-Resistant Human Breast Cancer: Increasing Magnitude and Duration of Response	Wen Jin Wu
09:05:00	Fc-Optimized Monoclonal Antibody for HER2- Expressing Tumors	Jeffrey L. Nordstrom
09:35:00	Optimization of a Monoclonal Antibody for Improved Anti-Tumor Efficacy	Gerald Casperson
10:05:00	Coffee Break, Poster and Exhibit Viewing
11:00:00	WHEN LESS IS MORE: ANTIBODY FRAGMENTS
11:05:00	Recombinant Immunotoxins for the Treatment of Hematologic Malignancies	Robert J. Kreitman
11:35:00	Engineered Avibodies Optimized for Clinical Diagnosis and Therapy	Peter Hudson
12:05:00	Luncheon Presentations (Sponsorship Opportunities Available) or Lunch on Your Own
13:05:00	Break
13:20:00	STABILITY, GLYCOSYLATION, IMMUNOGENICITY AND HUMANIZATION
13:25:00	Chairperson’s Remarks	Ira Pastan
13:30:00	Antibody Therapeutics: Isotype and Glycoform Selection	Roy Jefferis
14:00:00	Early Stage Engineering to Improve Pharmaceutical Properties of Antibodies	Alexey Lugovskoy
14:30:00	Networking Refreshment Break
15:00:00	Deimmunizing Non-Human Proteins	Ira Pastan
15:30:00	Antibody Optimization from Pharmacokinetic-Pharmacodynamic Perspectives	Liang Zhao
16:00:00	Probodies: Site-Directed Antibodies to Improve Therapeutic Indices	Nancy Stagliano
16:30:00	End of Conference

BiotechScienceNews.com promotes research and ranks life scientists working in the life science spectrum involving biotechnology,
drug discovery, genomics, microbiology, neuroscience, medicine, pharmacology, cell biology, and molecular biology.