| Thursday, May 20, 2010 |
| 12:00:00 |
Registration |
|
| 13:25:00 |
TARGETING, SPECIFICITY AND AFFINITY |
|
| 13:30:00 |
Chairperson’s Opening Remarks |
|
| 13:40:00 |
Conferring Meaningful Anti-Tumor Activity to Monoclonal Antibodies by Linking Cell Killing Agents |
Ravi V. Chari
|
| 14:10:00 |
Recombinant Human Multi-Domain Fusion Proteins |
Stefan Barth
|
| 14:40:00 |
Design and Produce Better Antibodies with Antigen Profiler |
Matt Baker
|
| 15:10:00 |
Networking Refreshment Break, Poster and Exhibit Viewing |
|
| 16:00:00 |
Optimizing Antibody Homogeneity and Development: Lessons Learned from Structural and Functional Studies |
Alain Beck
|
| 16:30:00 |
Antibody-Drug Conjugates to Improve Therapeutic Index |
Wei Liao
|
| 17:00:00 |
End of Day |
|
| Friday, May 21, 2010 |
| 07:45:00 |
Continental Breakfast in the Exhibit Hall |
|
| 08:25:00 |
HALF-LIFE, SENSITIVITY AND EFFICACY |
|
| 08:30:00 |
Chairperson’s Opening Remarks |
Gerald Casperson
|
| 08:35:00 |
Trastuzumab Conjugate for the Treatment of Trastuzumab-Resistant Human Breast Cancer: Increasing Magnitude and Duration of Response |
Wen Jin Wu
|
| 09:05:00 |
Fc-Optimized Monoclonal Antibody for HER2- Expressing Tumors |
Jeffrey L. Nordstrom
|
| 09:35:00 |
Optimization of a Monoclonal Antibody for Improved Anti-Tumor Efficacy |
Gerald Casperson
|
| 10:05:00 |
Coffee Break, Poster and Exhibit Viewing |
|
| 11:00:00 |
WHEN LESS IS MORE: ANTIBODY FRAGMENTS |
|
| 11:05:00 |
Recombinant Immunotoxins for the Treatment of Hematologic Malignancies |
Robert J. Kreitman
|
| 11:35:00 |
Engineered Avibodies Optimized for Clinical Diagnosis and Therapy |
Peter Hudson
|
| 12:05:00 |
Luncheon Presentations (Sponsorship Opportunities Available) or Lunch on Your Own |
|
| 13:05:00 |
Break |
|
| 13:20:00 |
STABILITY, GLYCOSYLATION, IMMUNOGENICITY AND HUMANIZATION |
|
| 13:25:00 |
Chairperson’s Remarks |
Ira Pastan
|
| 13:30:00 |
Antibody Therapeutics: Isotype and Glycoform Selection |
Roy Jefferis
|
| 14:00:00 |
Early Stage Engineering to Improve Pharmaceutical Properties of Antibodies |
Alexey Lugovskoy
|
| 14:30:00 |
Networking Refreshment Break |
|
| 15:00:00 |
Deimmunizing Non-Human Proteins |
Ira Pastan
|
| 15:30:00 |
Antibody Optimization from Pharmacokinetic-Pharmacodynamic Perspectives |
Liang Zhao
|
| 16:00:00 |
Probodies: Site-Directed Antibodies to Improve Therapeutic Indices |
Nancy Stagliano
|
| 16:30:00 |
End of Conference |
|
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