Biotech China 2014
Mechanism and Regulation of Prokaryotic Transcription
Vermont Academy, Saxtons River, Vermont
20 Pleasant St, Saxtons River, 05154, USA
mm, VT
http://src.faseb.org
1. RNA polymerase structure and function
2. Initiation and Escape I
3. Initiation and Escape II
4. Transcription elongation and termination
5. Sigma factors and anti-sigma factors
6. Interface of transcription with other cellular 
7. Stress Responses
8. Transcription Regulation
9. Bacterial nucleoid organisation

Schedule of Presentations:

Saturday, June 23, 2007
16:00:00 Conference Registration
18:00:00 FASEB Opening Reception
19:00:00 Dinner
20:30:00 “Small molecules: big effects on transcription”
21:15:00 “Sigma 38 transcription: characteristics and comparisons” Jay D Gralla
Sunday, June 24, 2007
07:30:00 Breakfast
09:00:00 “Molecular bioimaging of gene transcription” Patrick Cramer
09:30:00 “X-ray crystal structure of RNA polymerase from Archaea” Katsuhiko S Murakami
10:00:00 “Structural basis for substrate loading in bacterial RNA polymerase” Dmitri G Vassylyev
10:30:00 Group photo and FASEB-sponsored Coffee Break
11:15:00 “Molecular evolution of multi-subunit RNA polymerases” William Lane
11:30:00 “Mechanism of inhibition of RNA polymerase by rifampicin Andrey Feklistov
11:45:00 “Myxopyronin, corallopyronin, and ripostatin inhibit transcription by binding in the RNA polymerase 'switch region'" Jayanta Mukhopadhyay
12:00:00 Michael Gleghorn, Pennsylvania State University “Structural and functional basis for bacteriophage N4 minivRNAP promoter recognition”
12:30:00 Lunch
16:00:00 Poster Session 1
18:00:00 Dinner
19:00:00 “Roles of upstream and downstream DNA in open complex formation ” Ruth M Saecker
19:30:00 “Time-resolved footprinting of transcription initiation complexes” Bianca Sclavi
20:00:00 “Single molecule analysis of transcription” Richard Ebright
20:30:00 Break
21:00:00 “Real-time detection of the full transcription cycle by singlemolecule DNA nanomanipulation” Terence Strick
21:30:00 “Structural mechanism for the cascade of events that comprise promoter escape by T7 RNAP” Craig T Martin
21:45:00 “Transcription fidelity: parameters that affect sliding and idling of RNAP during elongation” Bill McAllister
Monday, June 25, 2007
07:30:00 Breakfast
09:00:00 “Region 1.1 of group 1 sigma factors” Ed Schwartz
09:30:00 “NusG inhibits sigma action during elongation” Rachel Mooney
09:45:00 “Determining the distribution of E. coli RNAP and associated proteins across transcribed regions in vivo” Joe Wade
10:00:00 “Sigma70 retention in elongation complexes in vivo” Rui Rong Niedfeldt
10:15:00 "Residence of GreB on RNAP and elongation complexes" Harini Ravi
10:30:00 "Modeling rRNA transcription" Stefan Klumpp
10:45:00 FASEB-sponsored Coffee Break
11:15:00 “Transcription activation via sigma 54 activators” Xiaodong Zhang
11:45:00 “Structure/function insights about regulation and function of sigma54-dependent bacterial enhancer binding proteins” Tracy Nixon
12:15:00 Lunch
16:00:00 Poster Session 2
18:00:00 Dinner
19:00:00 “Using force to probe the mechanism of transcription termination” Matthew Larson
19:30:00 “Regulation of transcript elongation and pausing” Robert Landick,
20:00:00 “Molecular mechanism of transcription regulation by RfaH”
20:30:00 Break
21:00:00 "Functional architecture of the T7 RNA polymerase transcription complex and the mechanism of pausing and termination at the T7 concatamer junction" Rui J Sousa
21:15:00 “Lambda Q interacts with the beta flap” Bryce E Nickels
21:30:00 “The phage 82 Q protein antiterminator constructs a NusAdependent shield to the emerging transcript” Jeffrey Roberts
21:45:00 “Archaeal transcription termination” Tom Santangelo
Tuesday, June 26, 2007
07:30:00 Breakfast
09:00:00 “Regulation of heat shock responses” Carol Gross
09:30:00 “The SigR-RsrA redox sensing system of Streptomyces Mark Paget
10:00:00 “Sensing stress: regulation of the extracytoplasmic stress factor, SigmaE” Sarah E Ades
10:30:00 FASEB-sponsored Coffee Break
10:45:00 “Genome-scale location data to reconstruct the transcription regulatory network for E. coli” Bernhard Palsson
11:00:00 “Characterization of a novel sigma factor in Bacillus subtilis” Shawn R MacLellan
11:30:00 “Structural basis of DNA recognition by sigma 54” Michaeleen Callahan Doucleff
12:15:00 Lunch
16:00:00 Poster Session 3
18:00:00 Dinner
19:00:00 “Transcription kinetics in E. coli: what does it mean for a gene to be ‘on’?” Ido Golding
19:30:00 “Mapping the input functions of E coli genes” Anat Bren
20:00:00 “Transcriptional networks in adaptive evolution” Eric M Knight
20:15:00 Break
20:45:00 “Bacterial Rho factor as a tool to monitor RNA polymerase II-dependent transcription in yeast” Rachid Rahmouni
21:15:00 “DNA translocation and transcription-coupled DNA repair” Nigel Savery
21:45:00 “Suppression of backtracking by RNA anchoring” Natalia Komissarova
Wednesday, June 27, 2007
07:30:00 Breakfast
09:00:00 “6S RNA regulation of transcription” Karen Wassarman
09:30:00 “Regulation of sigma 32 by the DnaK-DnaJ chaperone system”
10:00:00 “The role of IscR in sensing Fe-S stress” Patricia J Kiley
10:30:00 “OhrR and oxidative stress” Richard Brennan
10:30:00 FASEB-sponsored Coffee Break
11:00:00 “Control and function of Spx” Peter Zuber
11:45:00 “Regulation of the E. coli mar/sox/rob regulon” Robert G Martin
12:00:00 “RNA polymerase-associated proteins control virulence in Francissella tularensis” Simon Dove
12:15:00 Lunch
16:00:00 Poster Session 4
18:00:00 Dinner
19:30:00 “Cyclic-di-GMP signaling in ‘lifestyle’ switching in E. coli” Regine Hengge,
20:00:00 “Repression by binding of H-NS within a transcription unit” Karin Schnetz
20:30:00 “Regulation of transcription by nitric oxide”
21:00:00 Break
21:30:00 “Regulation of E. coli nucleoid-associated proteins” David Grainger
22:00:00 “The L-rhamnose response of the E. coli transcription activators RhaS and RhaR” Susan M Egan,
22:15:00 “Probing transcription factor dynamics at the single molecule level in a living cell” Gene Wei Li
Thursday, June 28, 2007
07:30:00 Breakfast
09:00:00 “How bacteria coordinate transcription, replication, and chromosome segregation during growth in rich medium” N. Patrick Higgins
09:30:00 “A model for all genomes: the role of transcription” Peter Cook
10:00:00 FASEB-sponsored Coffee Break
10:45:00 “Coupling the distribution of RNA polymerase, global gene expression and chromosome structure in Escherichia coli” Ding J Jin
11:15:00 “Structures of Fis bound to DNA- at last” Reid C Johnson
12:00:00 END OF CONFERENCE (Box Lunches Available)
4th Annual Pharma R&D Asia Congress
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