9th Annual Biomarkers Congress
Ubiquitin and Cancer: From Molecular Targets and Mechanisms to the Clinic

Schedule of Presentations:

Tuesday, January 22, 2008
19:00:00 KEYNOTE ADDRESS Vishva M. Dixit
20:00:00 OPENING RECEPTION
Wednesday, January 23, 2008
08:00:00 CONTINENTAL BREAKFAST
09:00:00 Ubiquitin Signaling in the NF-kB Pathway Zhijian James Chen
09:00:00 Structural Insights into the E3 Ligase Function of BRCA1/BARD1 Rachel Klevit
09:00:00 SESSION 1: ONCOGENIC SIGNALING I Alfred L. Goldberg
09:00:00 Siah in Hypoxia and Tumorigenesis Ze’ev A. Ronai
10:45:00 SESSION 1: ONCOGENIC SIGNALING I (continued)
10:45:00 Ubiquitin Recognition and Turnover in BRCA1 dependent DNA Repair and Tumor Suppression Roger A. Greenberg
10:45:00 A Novel Mitochondrial E3 Ligase Identified through Functional Genomics Claudio A.P Joazeiro
11:45:00 FREE TIME / LUNCH ON OWN
14:00:00 On EGFR Signaling and Ubiquitination Simona Polo
14:00:00 The Interplay between SUMOylation and Ubiquitylation Tony Hunter
14:00:00 Ubiquitin Networks in Oncogenic Signaling Ivan Dikic
14:00:00 SESSION 2: ONCOGENIC SIGNALING II Vishva M. Dixit
14:00:00 Two short talks from proffered abstracts
15:45:00 Mechanisms of Ubiquitin Chain Assembly and Substrate Degradation Raymond J Deshaies
15:45:00 SESSION 2: ONCOGENIC SIGNALING II (continued)
16:45:00 FREE TIME / DINNER ON OWN
19:15:00 POSTER SESSION A (with dessert reception)
Thursday, January 24, 2008
08:00:00 CONTINENTAL BREAKFAST
09:00:00 Role of Histone H2A Ubiquitylation in Polycomb Gene Silencing Yi Zhang
09:00:00 Control of DNA Methylation and Heterochromatic Silencing in Arabidopsis by Histone H2B Deubiquitination Jian-Kang Zhu
09:00:00 Histone H2B Ubiquitylation and Transcription Mary Ann Osley
09:00:00 SESSION 3: UBIQUITIN, TRANSCRIPTION, AND EPIGENETICS I Raymond J Deshaies
10:45:00 SESSION 3: UBIQUITIN, TRANSCRIPTION, AND EPIGENETICS I (continued)
10:45:00 Regulation of Transcription by the Proteasome in Embryonic Stem Cells Henrietta Szutorisz
10:45:00 Acquisition of Long-term Hematopoietic Reconstitution Ability by Multipotent Progenitors in Mice Deficient of the Bmi1 Targets Tp53 and Ink4a/Arf loci Michael F Clarke
12:15:00 POSTER SESSION B (lunch provided)
14:15:00 Two short talks from proffered abstracts
14:15:00 Regulation of Transcription Factor Sumoylation by MAP Kinase Signaling Andrew Sharrocks
14:15:00 Modulation of Transcription Factor Activity by Mono-ubiquitylation Thomas Kodadek
14:15:00 SESSION 4: UBIQUITIN, TRANSCRIPTION, AND EPIGENETICS II Mary Ann Osley
14:15:00 Translating Histone Crosstalk Between H2B Monoubiquitination and H3 Methylation by COMPASS and Dot1 Ali Shilatifard
16:00:00 Regulatory Mechanisms of Eukaryotic Transcription by the Proteasome and Histone H2B Ubiquitination in vivo Sukesh Bhaumik
16:00:00 SESSION 4: UBIQUITIN, TRANSCRIPTION, AND EPIGENETICS II (continued)
17:00:00 DINNER ON OWN / EVENING OFF
Friday, January 25, 2008
07:30:00 CONTINENTAL BREAKFAST
08:30:00 SESSION 5: CLINICAL AND PRECLINICAL STUDIES TARGETING THE UPS I Kenneth C Anderson
08:30:00 Phase I Studies with Carfilzomib (PR-171), A Novel Proteasome Inhibitor Susan M. Molineaux
08:30:00 Different Active Sites of the Proteasome as Drug Targets in Cancer Alexei F. Kisselev
08:30:00 New Insights into Proteasome Function Alfred L. Goldberg
08:30:00 Proteasome Inhibition for the Treatment of Hematological Malignancies Kenneth C Anderson
10:45:00 Two short talks from proffered abstracts
10:45:00 Proteasome Inhibitors and ER Stress in Pancreatic Cancer David J. McConkey
10:45:00 Proteasome Inhibition to Treat Solid Malignancies James C. Cusack
10:45:00 SESSION 6: CLINICAL AND PRECLINICAL STUDIES TARGETING THE UPS II Ze’ev A. Ronai
12:15:00 DEPARTURE
4th Annual Pharma R&D Asia Congress
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