Biotech China 2014
HIV Evolution, Genomics, and Pathogenesis (X7)
Whistler Conference Centre (meeting only)

Whistler, British Columbia
http://keystonesymposia.org/Meetings/ViewMeetings.cfm?MeetingID=1109
   Deadlines
   ---------

     *  Abstract Deadline:
       22nd November 2010

     *  Registration Deadline:
       21st January 2011


   Speakers
   --------

     *  Ashley T. Haase, University of Minnesota, USA

     *  Paul M. Sharp, University of Edinburgh, United Kingdom

     *  Aris Katzourakis, University of Oxford, United Kingdom

     *  Michael Worobey, University of Arizona, USA

     *  Short Talk(s) to be Chosen from Abstracts,

     *  John P. Moore, Weill Medical College of Cornell University, USA

     * 

     *  Speaker to be Announced,

     *  Peter A. Anton, University of California, Los Angeles, USA

     *  Speaker to be Announced,

     *  Short Talk(s) to be Chosen from Abstracts,

     *  Short Talks to be Chosen from Abstracts, ,

     *  Short Talks to be Chosen from Abstracts, ,

     *  Guido Silvestri, University of Pennsylvania School of Medicine,
       USA

     *  Cristian Apetrei, University of Pittsburgh, USA

     *  Michaela Müller-Trutwin, Institut Pasteur, France

     *  Speaker to be Announced,

     *  Nelson L. Michael, Walter Reed Army Institute of Research, USA

     *  Salim S. Abdool Karim, University of Natal, South Africa

     *  Short Talk to be Chosen from Abstracts,

     *  Theodora Hatziioannou, Aaron Diamond AIDS Research Center, USA

     *  Michael Emerman, Fred Hutchinson Cancer Research Center, USA

     *  Sebastian L. Bonhoeffer, ETH -Zentrum, Switzerland

     *  Short Talk(s) to be Chosen from Abstracts,

     *  Jo-Ann Passmore, University of Cape Town, South Africa

     *  Anuradha Ganesan, National Naval Medical Center, USA

     *  M. Juliana McElrath, Fred Hutchinson Cancer Research Center, USA

     *  Speaker to be Announced,

     *  Short Talk(s) to be Chosen from Abstracts,

     *  Andrew Leigh-Brown, University of Edinburgh, Scotland

     *  Brandon F. Keele, SAIC -Frederick, Inc., USA

     *  Carolyn Williamson, University of Cape Town, South Africa

     *  Short Talk to be Chosen from Abstracts,

     *  David B. Goldstein, Duke University, USA

     *  Manolis Emmanouil Dermitzakis, University of Geneva Medical
       School, Switzerland

     *  Monsef Benkirane, Institut de Genetique Humaine, France

     *  Amalio Telenti, Centre Hospitalier Universitaire Vaudois,
       Switzerland

     *  John R. Mascola, NIAID , National Institutes of Health, USA

     *  Peter D. Kwong, Vaccine Research Center, National Institutes of
       Health, USA

     *  Lynn Morris, National Institute for Communicable Diseases, South
       Africa

     *  Speaker to be Announced,

     *  Short Talk(s) to be Chosen from Abstracts,

     *  Short Talks to be Chosen from Abstracts, ,

     *  Frederic D. Bushman, University of Pennsylvania School of
       Medicine, USA

     *  Angela Ciuffi, Institute of Microbiology ( IMUL - CHUV ),
       Switzerland

     *  Paul de Bakker, Brigham and Women’s Hospital, USA

     *  Galit Alter, Massachusetts General Hospital, USA

     *  Georgia D. Tomaras, Duke University, USA

     *  Andrew J. McMichael, John Radcliffe Hospital, United Kingdom

     *  Short Talk to be Chosen from Abstracts,

     *  Vineet N. KewalRamani, National Cancer Institute, National
       Institutes of Health, USA

     *  Speaker to be Announced,

     *  Nolwenn Jouvenet, Aaron Diamond AIDS Research Center, USA

     *  Li Wu, Ohio State University, USA

     *  Louis J. Picker, Oregon Health & Science University, USA

     *  Robert Paul Johnson, Harvard Medical School, New England
       Physician Recruitment Center, USA

     *  Norman L. Letvin, Beth Israel Deaconess Medical Center, USA

     *  Speaker to be Announced,

     *  Short Talk(s) to be Chosen from Abstracts,

     *  Mario Roederer, National Institutes of Health, USA

     *  Melissa J. Robbiani (Pope), Population Council, USA

     *  Robin Shattock, St. Georges, University of London, United Kingdom

     *  Short Talk to be Chosen from Abstracts,

   Elucidating the molecular mechanisms of HIV pathogenesis relies on
   understanding the complex interplay between the virus and its host.
   Increasingly, the field is relying on the power of comparative studies
   of similar viruses in other species, and on whole genome analyses to
   elucidate which pathways are critical. The use of evolutionary
   analyses of both host and virus is also providing novel insights into
   viral transmission and innate immune responses. This Keystone Symposia
   meeting will use diverse disciplines to promote further insights into
   the dynamic interplay between the virus and the host in areas of
   pathogenesis, mucosal biology, the roles of viral and host genes, and
   viral latency. Understanding these issues is critical for the design
   and development of an effective vaccine and the next generation of
   antiviral agents.

Schedule of Presentations:

Sunday, March 20, 2011
15:00:00 Registration | Coat Check Area
18:15:00 Refreshments | Grand Foyer/Mountainview
19:15:00 Welcome and Keynote Address: Viral Transmission Dynamics (Joint) | Sea to Sky B/C
19:20:00 Founder events at the portal of entry in mucosal transmission Ashley T. Haase
Monday, March 21, 2011
07:00:00 Breakfast
08:00:00 Lentiviral Diversity | Sea to Sky B
08:05:00 The Endogenous Origins of HIV G-to-A Hypermutations Reuben S Harris
08:30:00 Endogenous Retroviruses and the Evolution of the Lentiviruses Aris Katzourakis
09:00:00 The tempo and mode of SIV and HIV outbreaks Michael Worobey
09:20:00 Coffee Break | Grand Foyer/Mountainview
09:45:00 Short Talk: A Chimpanzee CD4 Glycosylation Site Polymorphism Governs Susceptibility to SIVcpz Infection Frederic Bibollet-Ruche
10:30:00 Short Talk: Whole-Genome Deep-Sequencing of HIV-1 in the First Weeks, Months, and Years of Infection Will Fischer
11:00:00 Hands On Computer Workshop on Los Alamos Sequence Database
11:00:00 On Own for Lunch and Recreation
11:15:00 Poster Setup | Sea to Sky A
13:00:00 Poster Viewing | Sea to Sky A
14:30:00 Workshop 1: Innate Immune Sensing of Lentiviruses | Sea to Sky B
14:35:00 Innate Sensing of HIV-Infected Cells Olivier Schwartz
14:45:00 TLR-Mediated IFNalpha and IDO Production in pDC is Altered in African Green Monkeys Richard M. Dunham
15:00:00 HIV-1 Tat Mimics the Activity of Interferons in Primary Human Immature Dendritic Cells and Macrophages Anna Aldovini
15:20:00 Evolutionary Conservation of Lentiviral Interference with CD1d-Mediated Immunity M. Büchler
15:40:00 Vpu Prevents Natural Killer Cell Destruction of HIV-Infected Cells
16:00:00 Mechanistic Dissection of the Apobec3/Rfv3 Phenotype: Implications for Improving Retroviral Humoral Immunity Mario L. Santiago
16:30:00 Coffee Available | Grand Foyer/Mountainview
17:00:00 Non-Pathogenic Lentiviral Infections | Sea to Sky B
17:05:00 Towards an animal model for HIV/AIDS Theodora Hatziioannou
17:30:00 Pathogenesis of Cross-Species-Transmitted SIV Infection Cristian Apetrei
18:00:00 IFN-I related Responses in Non-pathogenic Versus Pathogenic SIV/HIV Infections Michaela Müller-Trutwin
18:30:00 Short Talk: Reduced Lymphatic Tissue Immunopathology and Altered Myeloid Lineage Cell Recruitment in SIV-Infected Rhesus Macaques Receiving Anti-TNFalpha Treatment
19:00:00 Social Hour w/ Lite Bites | Grand Foyer/Mountainview
19:30:00 Poster Session 1 | Sea to Sky A/Grand Foyer
Tuesday, March 22, 2011
07:00:00 Breakfast | Sea to Sky A/Garibaldi A/B
08:00:00 Evolution of Pathogenicity | Sea to Sky B
08:05:00 Protection of Central Memory CD4+ T Cell Homeostasis in Natural SIV Hosts
08:30:00 Paleovirology and the Evolution of Primate Antiviral Defenses Michael Emerman
09:00:00 Tracing Epidemiological Patterns in Sequence Data: Transmission Structure, Basic Reproductive Rate, and Heritability of Virus Load Sebastian L. Bonhoeffer
09:20:00 Coffee Break | Grand Foyer/Mountainview
09:40:00 Short Talk: Mechanisms Underlying Damage to the Mucosal Barrier and Immune Activation after Pathogenic SIV Infection of Rhesus Macaques
11:00:00 Poster Setup | Sea to Sky A
11:05:00 Hands On Computer Workshop on Los Alamos Sequence Database
11:10:00 On Own for Lunch and Recreation
13:00:00 Poster Viewing | Sea to Sky A
16:30:00 Coffee Available | Grand Foyer/Mountainview
17:00:00 Viral Variation from Transmission to Populations (Joint) | Sea to Sky B/C
17:05:00 HIV Transmission Dynamics Andrew Leigh-Brown
17:30:00 Modeling HIV Transmission and Early Evolution in Nonhuman Primates
18:00:00 Early Viral Evolution and Escape in Subtype C Infected Individuals with Single- and Super-Infection Carolyn Williamson
18:30:00 Short Talk to be Chosen from Abstracts
19:00:00 Social Hour w/ Lite Bites | Grand Foyer/Mountainview
19:30:00 Poster Session 2 | Sea to Sky A/Grand Foyer
Wednesday, March 23, 2011
07:00:00 Breakfast | Sea to Sky A/Garibaldi A/B
08:00:00 Host Genome I: The Variable Human Genome | Sea to Sky B
08:05:00 Whole Genome Sequencing and the Host Genetics of HIV-1 Acquisition and Viral Control David B. Goldstein
08:30:00 Human Cellular Quantitative Genetics Manolis Dermitzakis
09:00:00 Small Non-Coding RNAs/miRNAs in HIV Infection Monsef Benkirane
09:20:00 Coffee Break | Grand Foyer/Mountainview
09:40:00 Host and Pathogen Evolution at Genome Scale Amalio Telenti
10:00:00 Short Talk: Mapping HIV-1’s Perturbation of the Host System David L. Robertson
11:00:00 Poster Setup | Sea to Sky A
11:05:00 On Own for Lunch and Recreation
13:00:00 Poster Viewing | Sea to Sky A
14:30:00 Workshop 2: HIV/Host Interactions | Sea to Sky B
14:35:00 Homeostatic Proliferation of Central Memory T Cells and the Latent HIV-1 Reservoir Vicente Planelles
15:00:00 Quantitative Multicolour Super-Resolution Microscopy Reveals Tetherin HIV-1 Interaction Vincent Piguet
15:20:00 Analysis of Tetherin Antagonism by HIV-1 Vpu and HIV-2 Env Alleles Isolated from Infected Individuals
15:40:00 An Intrinsic Inhibitor of CDK9-Mediated Transcriptional Elongation of HIV-1 in CD4 T Cells from Elite Controllers Chun Li
15:50:00 HIV-1 N-Glycan Composition Governs a Balance between Dendritic Cell-Mediated Viral Transmission and Degradation
16:05:00 Live Cell Imaging of Cell-Associated Viral Capture by Mature Dendritic Cells
16:20:00 An Update on HIV Proteomics: Comparisons between Macrophage and T Cell Derived HIV-1 David Graham
16:30:00 Coffee Available | Grand Foyer/Mountainview
17:00:00 Host Genome II: Host Genome and Retroviral Infection | Sea to Sky B
17:05:00 HIV DNA integration: mechanism and consequences F D Bushman
17:30:00 Host Transcriptional Reprogramming during the HIV Life Cycle Angela Ciuffi
18:00:00 Unravelling the Genetic Contributions of MHC Variation to Durable Host Control of HIV-1 Paul de Bakker
18:30:00 Short Talk: Deep Sequencing of Small RNAs from HIV-1 Infected Cells Reveals Possible HIV-Encoded miRNAs Nick Schopman
19:00:00 Social Hour w/ Lite Bites | Grand Foyer/Mountainview
19:30:00 Poster Session 3 | Sea to Sky A/Grand Foyer
Thursday, March 24, 2011
07:00:00 Breakfast | Sea to Sky A/Garibaldi A/B
07:30:00 Poster Setup | Sea to Sky A
08:00:00 Poster Viewing | Sea to Sky A
08:05:00 HIV Host Interactions | Sea to Sky B
08:10:00 Genetics of HIV Entry into the Nucleus Vineet N. KewalRamani
08:30:00 TRIM5 is an Innate Immune Sensor for the Capsid of HIV-1 and Other Retroviruses Jeremy Luban
09:00:00 Coffee Break | Grand Foyer/Mountainview
09:20:00 HIV Interactions with Dendritic Cells Li Wu
09:40:00 Short Talk: Reverse Transcription Facilitates HIV Uncoating Thomas J. Hope
10:10:00 Short Talk: Neutralization Resistance of HIV-1 Virological Synapse-Mediated Infection is Regulated by Env Cytoplasmic Tail Benjamin K. Chen
11:00:00 On Own for Lunch and Recreation | Sea to Sky A/Garibaldi A/B
12:00:00 Poster Session 4 | Sea to Sky A
16:30:00 Coffee Available | Grand Foyer/Mountainview
17:00:00 Targeting Mucosal and T Cell Immunity (Joint) | Sea to Sky B/C
17:05:00 Identification and Characterization of T Memory Stem Cells in Humans and NHP: Implication for Vaccine Design Mario Roederer
17:30:00 Virus-Cell Interplay and Modulation of Immune Function Elena Martinelli
18:00:00 Combining Prevention Technologies: Vaccines and Microbicides Robin Shattock
18:30:00 Short Talk to be Chosen from Abstracts,
19:00:00 Social Hour w/ Lite Bites | Grand Foyer/Mountainview
20:00:00 Entertainment | Sea to Sky A
Friday, March 25, 2011
09:00:00 Departure
4th Annual Pharma R&D Asia Congress
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