9th Annual Biomarkers Congress
Congress on Steroid Research
The Westin Chicago River North
320 North Dearborn Street
Chicago, Illinois

Schedule of Presentations:

Sunday, March 27, 2011
14:00:00 Plenary lecture
14:30:00 Novel roles of ERbeta and LXRbeta in neuronal cortical migration and epithelial proliferation Jan-Åke Gustafsson
15:00:00 Session | Short Oral Communications 1
16:00:00 Coffee break
16:30:00 Session | Receptors
16:45:00 Long-range transcriptional control of progesterone receptor gene expression Ann Nardulli
17:00:00 Differential signaling mechanisms for ERalpha and ERbeta in response to diverse ligands Geoff L. Greene
17:15:00 The role of the androgen receptor at all states of untreated and treated prostate cancer Fernand Labrie
17:30:00 The K303R Estrogen Receptor Alpha Mutation and Hormone Resistance in Breast Cancer Suzanne AW Fuqua
18:30:00 Poster Session 1
Monday, March 28, 2011
08:30:00 Session: Mechanisms of signal transduction
08:45:00 New activities of GPR30 and its selective ligands Eric Prossnitz
09:00:00 Protein Kinase Inputs to PR actions in breast cancer models Carol A. Lange
09:15:00 Targeting androgen receptors in androgen-dependent and androgen-independent prostate cancer Nancy Lynn Weigel
10:00:00 High Throughput and Standardized LC-MS/MS Steroid-Quantification for Clinical Metabolomics Therese Koal
10:30:00 Coffee break
11:00:00 Session | Pre-receptor metabolism
11:15:00 Epigenetics meets metabolism: Chemical biology to modulate SDR protein family Udo Oppermann
11:30:00 Coupling of 11beta-hydroxysteroid dehydrogenase 1 functions to energy supply and NADPH generation in the endoplasmic reticulum Alex Odermatt
11:45:00 11Beta-hydroxysteroid dehydrogenase type 1 and its role in the hypothalamus-pituitary-adrenal axis, metabolic syndrome, and inflammation Paul M. Stewart
12:00:00 A combined genomic and proteomic study demonstrating a special function of 17beta-hydroxysteroid dehydrogenase type 1
13:00:00 Lunch
14:00:00 Session | Steroidogenesis
14:15:00 The multiple roles of estrogens and the enzyme aromatase Evan R. Simpson
14:30:00 Estrogen and androgen measurements in breast and prostate tissues: what have we learned Frank Stanczyk
14:45:00 Steady-state hydroxysteroid/ketosteroid ratios catalyzed by hydroxysteroid dehydrogenases: Can we force an oxidative enzyme to favor reduction? Richard J. Auchus
15:30:00 New functionalities of steroid metabolizing SDR-enzymes revealed by animal models Matti Poutanen
16:00:00 Coffee break
16:30:00 Session | Chemistry of synthesis
17:00:00 Synthesis and biological evaluation of non- estrogenic steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 Donald Poirier
17:15:00 Anticancer Agents Incorporating the Aryl Sulfamate Pharmacophore: Design, Synthesis and Clinical Translation Barry V Potter
17:30:00 Efficient strategies for the development of potent and selective steroidogenic enzyme inhibitors
18:00:00 ent-Steroids: Novel Reagents for Studies of Membrane Receptors and Membrane Properties Douglas F. Covey
18:30:00 Poster Session 2
Tuesday, March 29, 2011
08:30:00 Session | Environmental challenge
08:45:00 Obesogens, Stem Cells, and the Maternal Programming of Obesity Bruce Blumberg
09:00:00 Developmental Origins of Disease: Role of Environmental Exposures and Epigenetics Jerry Heindel
09:15:00 Neonatal exposure to estrogens or environmental estrogens induces aberrant promoter methylation and expression of nucleosomal binding protein (Nsbp1) in later-life Mitchell Ho
10:00:00 Childrens toxicology “early exposure-delayed effects Jun Kanno
10:30:00 Coffee break
11:00:00 Session | Cancer
11:15:00 Molecular basis of de novo and acquired aromatase inhibitor resistance S Cheng
11:30:00 Pre-receptor Regulation of the Androgen Receptor in Prostate Cancer Trevor R. Penning
11:45:00 In situ estrogen production and its actions in human lung cancer Hironbu Sasano
12:30:00 Genomics of Estrogen Receptor Signaling and Actions in Breast Cancer Benita S. Katzenellenbogen
13:00:00 Lunch
14:00:00 Session | Diabetes and Obesity
14:30:00 Obesity, aromatase and breast cancer: classic concepts and a novel mechanism Serdar E. Bulun
14:45:00 Mechanisms linking glucocorticoids with cardiovascular risk Brian R. Walker
15:00:00 Metabolic impact of sex hormones on obesity Deborah Joy Clegg
15:30:00 Familial Phenotypes in the Polycystic Ovary Syndrome Andrea Dunaif
16:00:00 Coffee break
16:30:00 Session | Short Oral Communications 1
17:30:00 Awards
17:45:00 Plenary lecture 2
18:00:00 Steroid receptors: structure, function, ligand design, and in vivo imaging John A. Katzenellenbogen
4th Annual Pharma R&D Asia Congress
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