Biotech China 2014
Difficult to Express Proteins
Intercontinental Hotel Boston Massachusetts
510 ATLANTIC AVENUE
BOSTON, 02210 • UNITED STATES, MA
www.PEGSummit.com
the essential protein engineering summit,
Phage Display
Diffi cult to Express Proteins
Recombinant Antibodies
Monoclonal Antibodies
Engineering Proteins for Delivery
Clinical Development of
Therapeutic Antibodies
Immunogenicity in Clinical Trials
Protein Scale-Up & Manufacturing
Phage Display of Antibodies and Peptides,
SELECTION IN COMPLEX SYSTEMS: CREATING
FUNCTIONALLY DIVERSE LIBRARIES

Event Sponsors

Schedule of Presentations:

Sunday, April 27, 2008
14:00:00 Protein Folding, Re-Folding and Aggregation
16:00:00 Conference Pre-Registration
18:00:00 END
Monday, April 28, 2008
07:00:00 Registration Open
08:30:00 KEYNOTE ADDRESS Chairperson’s Opening Remarks
08:40:00 Recombinant Proteins and Antibodies in Mammalian Cells From DNA to Process at Large Scale - Today and Tomorrow Florian M Wurm
09:10:00 NOVEL VECTORS AND HOSTS NOVEL VECTORS AND HOSTS New Vector Technology for Membrane Protein Production Larry J DeLucas
09:40:00 An E. coli Vector-Based Antigen Expression System for the Construction of Novel Vaccines Eric Huang
10:10:00 Grand Opening Coffee Break in the Exhibit Hall
11:10:00 Dual-Promoter Lentiviral System allows Inducible Expression of Noxious Proteins in Macrophages Igor Kramnik
11:40:00 Chaperna Technology: Use of RNA as Molecular Chaperone Baik Seong
12:10:00 New High-Yield Eukaryotic Protein Expression System Based on the Protozoan Leishmania Tarentolae Kirill Alexandrov
12:40:00 Luncheon Workshop (Sponsorship Available)or Lunch on Your Own
13:40:00 Break
14:00:00 Chairperson’s Remarks THE STATE-OF-THE-ART THE STATE-OF-THE-ART
14:05:00 Biosynthesis of Folded Cyclotides Inside Living Bacterial Cells Julio A. Camarero
14:35:00 Solutions Showcase I: Sponsored by Largest Comparative Study on Expression Improvement by Gene Optimization: Results and Applications Hans Bügl
14:50:00 Solutions Showcase II: Sponsored by What’s on TAP at Blue Sky Biotech?...A Novel Tandem Affi nity Purifi cation System! Rajiv Gangurde
15:05:00 Refreshment Break in the Exhibit Hall
15:45:00 Using an Engineered Solubilization Tag to Achieve Enhanced Protein Expression and Purifi cation Based on Covalent Immobilization Rachel Friedman Ohana
16:15:00 SuggestES:A Tool for Selecting the Best Expression System Jaime Prilusky
16:45:00 Problem-Solving Break-Out Sessions
17:45:00 Networking Cocktail Reception in the Exhibit Hall
Tuesday, April 29, 2008
08:00:00 Registration Open
08:25:00 Chairperson’s Remarks SOLVING PROTEIN EXPRESSION PROBLEMS THROUGH PROTEIN ENGINEERING
08:30:00 Soluble Nanolipoprotein Particles (NLPs) Containing Functional Integral Membrane Proteins Form in situ During Cell-Free Protein Synthesis Paul Hoeprich
09:00:00 Development of a High-Throughput ENaC Ionworks Quattro Assay, using BacMan Technology Horst Werner Korf
09:30:00 Hybrid IL17RA/IL17RC-Fc Fusion Protein as a Soluble Inhibitor of IL17A and IL17F Mark Rixon
10:00:00 Coffee Break in the Exhibit Hall
10:45:00 P-gel: A DNA Gel That is Able to Produce Proteins without any Living Cell APPLICATIONS AND ISSUES APPLICATIONS AND ISSUES Dan Luo
11:15:00 Orfeus Expression System: A Biorisk-Free Option Björn Örvar
11:45:00 From Neanderthal to Nanobiotech: From Plant Potions to Pharming—Should We Make the Switch to Plant Expression? Loïc FAYE
12:15:00 Luncheon Workshop (Sponsorship Available) or Lunch on Your Own
13:15:00 Break CASE STUDIES
14:00:00 Chairperson’s Remarks
14:05:00 Engineering ScFv with a Lipophilic Tail for Ectoplasmic Insertion into Targeting Liposomes Anton Scott Goustin
14:35:00 In Vitro Selection and Characterization of DARPins and Fab Fragments for the Co-Crystallization of Membrane Proteins Thomas Huber
15:05:00 Solutions Showcase I Sponsored by Novel Small-Molecule Additives to Refold Proteins A Simultaneous and Systematic Evaluation Peter A Leland
15:20:00 Solutions Showcase II (Sponsorship Available)
15:35:00 Refreshment Break in the Exhibit Hall
16:15:00 Strategies for the Expression of Difficult Protein Targets at the Midwest Center for Structural Genomics Gyorgy Babnigg
16:45:00 Title to Be Determined Paul Ramage
17:15:00 End of Conference
4th Annual Pharma R&D Asia Congress
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