9th Annual Biomarkers Congress
Clinical Development of Therapeutic Antibodies
Intercontinental Hotel Boston
500 Atlantic Ave
BOSTON, 02210 • UNITED STATES, MA
www.PEGSummit.com
the essential protein engineering summit,
Phage Display
Diffi cult to Express Proteins
Recombinant Antibodies
Monoclonal Antibodies
Engineering Proteins for Delivery
Clinical Development of
Therapeutic Antibodies
Immunogenicity in Clinical Trials
Protein Scale-Up & Manufacturing
Phage Display of Antibodies and Peptides,
SELECTION IN COMPLEX SYSTEMS: CREATING
FUNCTIONALLY DIVERSE LIBRARIES

Event Sponsors

Schedule of Presentations:

Monday, April 28, 2008
08:30:00 Short Course Registration
09:00:00 Pre-Conference Short Course (SC2) Preclinical Development Antibodies
14:00:00 Chairperson’s Opening Remarks PRECLINICAL DEVELOPMENT Mohammad Tabrizi
14:05:00 Normalizing Tumor Vessels and Microenvironment to Treat Cancer: From the Bench to Bedside and Back Melanie Jawerka, Rakesh K Jain
14:35:00 Technologies for the Discovery of Therapeutic Monoclonal Antibodies Larry L Green
15:05:00 Refreshment Break in the Exhibit Hall
15:45:00 Optimizing Engagement of the Immune System by Anti-Tumor Antibodies: An Engineer’s Perspective John R Desjarlas
16:15:00 Challenges in Development of Monoclonal Antibodies Steve Coats
16:45:00 Development of a New Fully Human Anti-CD20 Monoclonal Antibody for the Treatment of B-Cell Malignancies Gadi Bornstein
17:15:00 Networking Cocktail Reception in the Exhibit Hall
Tuesday, April 29, 2008
08:00:00 Registration Open
08:25:00 Chairperson’s Remarks TRANSLATIONAL MEDICINE Mohammad Tabrizi
08:30:00 Dosing Strategies with Monoclonal Antibodies Transition from Discovery to the Clinic Mohammad Tabrizi
09:00:00 Science-Based Regulatory Strategies in Transitioning Monoclonal Antibodies into Clinical Trials Joy A. Cavagnaro
09:30:00 Preclinical and Clinical Safety of Monoclonal Antibodies Richard Knight
10:00:00 Coffee Break in the Exhibit Hall
10:45:00 How PK/PD Impacts Translational Research and Clinical Study Design for Oncology Protein Therapeutics Y Sun
11:15:00 Solution Showcase
11:45:00 Anti-CD44 Variant-Disease-Specifi c Monoclonal Antibody David Naor
12:15:00 Luncheon Workshop (Sponsorship Available)
13:15:00 Break CLINICAL DEVELOPMENT
14:00:00 Chairperson’s Remarks
14:05:00 Affi body Molecules for Molecular Imaging of HER2-Expressing Malignant Tumors Clinical and Preclinical Applications Joachim Feldwisch
14:35:00 Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange Janine Schuurman
15:05:00 The Development of Antiangiogenics in Lung Cancer Jane Huang
15:35:00 Refreshment Break in the Exhibit Hall
16:15:00 Novel Antibody Therapeutic Approaches for B cell Neoplasias and Infl ammation Jørgen Otzen Petersen
16:45:00 Immunoprophylaxis of RSV Infection Advancing from RSV-IGIV to Palivizumab and Motavizumab Herren Wu
17:15:00 End of the conference
4th Annual Pharma R&D Asia Congress
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