9th Annual Biomarkers Congress
Signal Transduction within the Nucleus Gordon Research Conference
Four Points Sheraton

Ventura, California
http://www.grc.org/programs.aspx?year=2011&program=sigtrans
   Deadlines
   ---------

     *  Registration Deadline:
       30th January 2011

   This conference provides an outstanding forum to present and discuss
   new findings for how signaling pathways participate in the regulation
   of nuclear processes. The program will consist of morning and evening
   sessions that broadly address cutting-edge issues in the following
   areas: nucleo-cytoplasmic signaling, the physiology of stress
   responses, nuclear lipid signaling, nuclear receptor signaling,
   agonist-induced nuclear lipid and carbohydrate metabolism, chromatin
   composition and functional role, DNA damage/repair pathways, nuclear
   organization and spatial architecture, nuclear membrane dynamics, RNA
   processing and export, and control of nuclear division. Small,
   intensive poster sessions will be convened in the later afternoons,
   allowing all participants to contribute to and learn about these
   topics. Informal discussions among established and junior principal
   investigators, postdoctoral fellows, and students will be stimulated
   during early-afternoon and late-evening breaks. This conference will
   offer a timely and highly topical program allowing the investigators
   to connect the newly discovered signaling pathways and nuclear
   functions.

Schedule of Presentations:

Sunday, February 27, 2011
16:00:00 Arrival and Check-in
18:00:00 Dinner
19:30:00 Welcome / Introductory Comments by GRC Site Staff
19:40:00 Welcome / Introductory Comments by Conference Co-Chairs
19:50:00 The Unfolded Protein Response
19:55:00 The Unfolded Protein Response in Health and Disease Peter Walter
20:20:00 Discussion
20:35:00 Informal Poster Session
Monday, February 28, 2011
07:30:00 Breakfast
08:30:00 Group Photo
09:00:00 Stress Signaling
09:05:00 Protein misfolding in the ER and oxidative stress Randal J. Kaufman
09:25:00 Discussion
09:35:00 Partitioning the mRNA transcriptome: Bimodal regulation of mRNA localization to the endoplasmic reticulum Chris Nicchitta
10:00:00 Discussion
10:10:00 Coffee Break
10:40:00 Cellular addiction on Ceramide Flux - A CERT'nty Jairaj Acharya
11:05:00 Discussion
11:10:00 FoxO transcription factors in aging and longevity Anne Brunet
11:35:00 Discussion
11:45:00 Modulation of endogenous kinase activity in human cells via codon editing using zinc finger nucleases Gregory D. Davis
12:10:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:30:00 Transcriptional Regulation by RNA Polymerase II and Chromatin Ali Shilatifard
19:35:00 Chromatin and Its Impact on Gene Expression and Cellular Memory Danny Reinberg
20:10:00 Discussion
20:30:00 Informal Poster Session
Tuesday, March 1, 2011
07:30:00 Breakfast
09:00:00 Nuclear Inositide and Lipid Signaling John York
09:05:00 Regulation of nucleocytoplasmic transport Susan Wente
09:25:00 Discussion
09:35:00 Regulation and function of nuclear phosphatidylinositol-5-phosphate Nullin Divecha
10:00:00 Discussion
10:10:00 Coffee Break
10:40:00 Physiology and pathology of nuclear inositide signalling Lucio Cocco
11:05:00 Discussion
11:10:00 Sphingosine-1-phosphate lyase regulates DNA damage responses Julie Saba
11:35:00 Discussion
11:45:00 Mechanisms of nucleocytoplasmic transport of phospholipase C-delta1 and its role in cellular function Hitoshi Yagisawa
12:00:00 Discussion
12:05:00 Short Presentation Selected from Abstracts
12:20:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:30:00 Nuclear Organization Michael Rout
19:35:00 Epigenetic regulation of alternative splicing T Misteli
19:55:00 Discussion
20:05:00 Understanding the nuclear functions of eIF4E in mRNA export: from cells to the clinic Katherine Borden
20:30:00 Discussion
20:40:00 Transport complex assembly and disassembly during nucleocytoplasmic transport visualized by single molecule FRET Siegfried Musser
21:05:00 Discussion
Wednesday, March 2, 2011
07:30:00 Breakfast
09:00:00 RNA, Chromatin, and Nuclear Signaling Ramin Shiekhattar
09:05:00 Long Noncoding RNAs with Enhancer-like Function in Human Cells Ramin Shiekhattar
09:25:00 Discussion
09:35:00 Control of chromosome organization and stability by inner nuclear membrane proteins Danesh Moazed
10:00:00 Discussion
10:10:00 Coffee Break
10:40:00 A multitude of mutations in the human lamin A gene are providing new insights into the functional organization of the nucleus Robert D Goldman
11:05:00 Discussion
11:10:00 Speaker TBA
11:35:00 Discussion
11:45:00 Short Presentation Selected from Abstracts
12:00:00 Discussion
12:05:00 Short Presentation Selected from Abstracts
12:20:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:00:00 Business Meeting
19:30:00 Chromatin and the Regulation of Gene Expression Sue L. Jaspersen
19:35:00 The function of spindle pole body proteins in nuclear chromosome dynamics Sue L. Jaspersen
19:55:00 Discussion
20:05:00 Chromatin and aging Shelly Berger
20:30:00 Discussion
20:40:00 Map kinases and histone modifications
21:05:00 Discussion
Thursday, March 3, 2011
07:30:00 Breakfast
09:00:00 Signaling to the Nucleus Pascale Zimmermann
09:05:00 Transcriptional control by endosomal sorting factors in yeast Alan Hinnebusch
09:25:00 Discussion
09:35:00 Using yeast functional genomics to map transcriptional regulatory networks and pathways Brenda Andrews
10:00:00 Discussion
10:10:00 Coffee Break
10:40:00 Temporal coding of AKT and ERK signaling networks Shinya Kuroda
11:05:00 Discussion
11:45:00 Short Presentation Selected from Abstracts
12:00:00 Discussion
12:05:00 Short Presentation Selected from Abstracts
12:20:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:30:00 The RNA Polymerase II, Chromatin and Cancer
19:35:00 PARP1-dependent responses in the function and localization of chromatin regulators
19:55:00 Discussion
20:05:00 Regulation of mRNA transcription by non-coding RNAs Jim Goodrich
20:30:00 Discussion
20:40:00 Comprehensive analysis of a cancer epigenome Bing Ren
21:05:00 Discussion
Friday, March 4, 2011
07:30:00 Breakfast
09:00:00 Departure
4th Annual Pharma R&D Asia Congress
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