Biotech China 2014
NEW ANTIBACTERIAL DISCOVERY & DEVELOPMENT
Il Ciocco Hotel and Resort

Lucca (Barga),
http://www.grc.org/programs.aspx?year=2008&program=antibact

Schedule of Presentations:

Sunday, March 9, 2008
16:00:00 Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm)
18:00:00 Dinner
19:30:00 Welcome: Bob Hancock, Chair (University of British Columbia) / Introductory Comments by GRC Site Staff
19:35:00 The Picture Today and Tomorrow - Keynote Addresses
19:35:00 Discussion Leader: Trevor Trust (Astra Zeneca)
19:45:00 Resistance: Lessons to learn Julian E Davies
20:30:00 What is in the future for antibiotics?
21:15:00 General Discussion
21:30:00 Reception
Monday, March 10, 2008
07:30:00 Breakfast
09:00:00 Conventional Targets Lynn Silver
09:00:00 What makes a good antibiotic target
09:25:00 Discussion
09:35:00 Antibiotic interactions to discourage resistance development Roy Kishony
10:00:00 Discussion
10:10:00 Cell Walls as a target
10:35:00 Discussion
10:45:00 Coffee Break / Group Photo
11:15:00 Cell Division as a target
11:20:00 DNA synthesis as a target Ann E Eakin
11:45:00 Discussion
11:55:00 Cell Division as a target Roger C Levesque
12:20:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session 1
17:30:00 Differences between in vitro and in vivo lifestyle Jay Hinton
17:30:00 Screening Strategies and Hit Generation
17:55:00 Discussion
18:05:00 Back to the Future': Towards New Antibacterials with Reversed Genomics and Chemical Post-Evolution of Natural Products
18:30:00 Discussion
18:40:00 (Do we need) New screening strategies (?) Jennifer Leeds
19:05:00 Discussion
19:15:00 Selected Poster Presentation
20:00:00 Dinner
21:15:00 Poster Session 1 (continued); Beverages available
Tuesday, March 11, 2008
07:30:00 Breakfast
09:00:00 Alternative Antibacterial Approaches
09:00:00 Therapeutic Antibodies
09:25:00 Discussion
09:35:00 Selective Immunomodulators John R North
10:00:00 Discussion
10:10:00 Using phage lytic enzymes to control pathogenic bacteria
10:35:00 Discussion
10:45:00 Coffee Break
11:25:00 Probiotics and Perinatal Health Alan D Bocking
11:50:00 Discussion
12:00:00 Selected Poster Presentations
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session 2
17:05:00 Discussion
17:30:00 The regulatory perspective
17:30:00 Pre-clinical and Clinical Considerations David Payne
18:00:00 Clinical considerations for a new antibiotic John Rex
18:25:00 Discussion
18:30:00 Infection site antibiotic concentrations and their meaning Keith A Rodvold
19:00:00 Sepsis as a major threat to antibiotic outcomes Robert S. Munford
19:25:00 Discussion
20:00:00 Dinner
21:15:00 Poster Session 2 (continued); Beverages available
Wednesday, March 12, 2008
07:30:00 Breakfast
09:00:00 Gram Negative Active Drugs Laura Piddock
09:00:00 Revival of the polymyxins Matthew E Falagas
09:25:00 Discussion
09:35:00 The evolution of the innate immunity antibiotic Tim Falla
10:00:00 Discussion
10:10:00 Identifying new targets for Salmonella through in vivo screening
10:35:00 Discussion
10:45:00 Coffee Break
11:25:00 Structural biology approaches to understanding antibiotic mechanisms and resistance Natalie C.J Strynadka
11:50:00 Discussion
12:00:00 Selected Poster Presentations
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session 3
17:30:00 Novel Targets and Overcoming Resistance Jared A Silverman
17:30:00 Where are we with Resistance?
17:55:00 Discussion
18:00:00 New strategies to develop novel targets: Platensimycin, a selective FabF inhibitor Sheo B Singh
18:25:00 Discussion
18:30:00 Structure and mechanism of bacterial multi-drug efflux systems Satoshi Murakami
18:55:00 Discussion
19:00:00 Probing uncharted physiology in bacteria with new (and old) small molecules Eric D Brown
19:25:00 Discussion
20:00:00 Dinner
21:15:00 Poster Session 3 (continued); Beverages available
Thursday, March 13, 2008
07:30:00 Breakfast
09:00:00 Selected Topics & Late Breakers
09:00:00 Selected Topics and Late Breakers: Attendees are invited to discuss topics of interest in less than 5 minutes with 5 slides (strictly regulated). Presenters will be selected at the Gordon Conference by the Chair.
10:40:00 Coffee Break
11:10:00 Business Meeting
11:30:00 Recent Experience with Clinical Trials
11:30:00 Anti-resistance; ceftobiprole, an anti-MRSA broad-spectrum cephalosporin antibiotic
11:55:00 Discussion
12:25:00 Discussion
12:30:00 Lunch
17:30:00 Towards More Efficient Antibacterial Development
18:05:00 Experiences in fragment-based drug discovery
18:30:00 Discussion
18:40:00 Multiple mode of action antibiotics: some lessons from nature and application in antibiotic design
19:50:00 Discussion
20:00:00 Dinner
Friday, March 14, 2008
07:30:00 Breakfast
09:00:00 Depart
4th Annual Pharma R&D Asia Congress
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