Biotech China 2014
LIGAND RECOGNITION & MOLECULAR GATING

Schedule of Presentations:

Sunday, March 2, 2008
16:00:00 Arrival and Check-in
18:00:00 Dinner
19:30:00 Welcome / Introductory Comments by GRC Site Staff
19:40:00 Structures of ABC transporters facilitating nutrient uptake or drug extrusion
19:40:00 KEYNOTE LECTURE Susan Buchanan
20:40:00 Discussion
Monday, March 3, 2008
07:30:00 Breakfast
09:00:00 Activation and allostery in glutamate receptor ion channels: Insights from crystallographic and functional studies Mark L Mayer
09:00:00 LIGAND-GATED ION CHANNELS
09:20:00 Discussion
09:30:00 Modular design and constraints for homology models of the GABA and 5-HT3 neurotransmitter-gated ion channels Myles H Akabas
09:50:00 Discussion Steven Smith
10:00:00 Coffee Break
10:30:00 Individual proton-transfer events as a probe of the structure and electrostatics of the nicotinic-receptor channel pore
10:50:00 Discussion
11:00:00 Poster Contribution (TBA)
11:15:00 Group Photo
11:30:00 Structural mechanisms of K+ channel activation and inactivation gating Eduardo Perozo
11:50:00 Discussion
12:00:00 Crystal structure of an acid-sensing ion channel
12:20:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session I
18:00:00 Dinner
19:30:00 MEMBRANE PROTEINS ASSESSED BY NMR
19:30:00 Combination of cell-free expression and NMR spectroscopy for the structure determination of membrane proteins Volker Dötsch
19:50:00 Discussion
20:00:00 Assembly and structural changes of bacterial chemotaxis receptor signaling complexes
20:20:00 Discussion
20:30:00 Poster Contribution (TBA)
20:50:00 Discussion
21:00:00 Solid-state NMR studies on the activated state of rhodopsin
21:20:00 Discussion
Tuesday, March 4, 2008
07:30:00 Breakfast
07:30:00 Insertion of transmembrane helices into the ER: experiment-based computational models
09:00:00 Wza, a new class of membrane protein Jim Naismith
09:00:00 SMALL AND LARGE MOLECULE TRANSPORT Carola Hunte
09:20:00 Discussion
09:30:00 Dynamics of substrate binding, gating, and energy coupling in membrane transporters
09:50:00 Discussion
10:00:00 Coffee Break
10:30:00 Structure of the human copper transporter CTR1
10:50:00 Discussion
11:00:00 Structural basis for the function and pharmaceutical inhibition of an influenza virus proton channel
11:20:00 Discussion
11:30:00 The AmtB-GlnK complex: regulating the bacterial ammonia channel
11:50:00 Discussion
12:00:00
12:00:00
12:00:00 Structure-Function of CorA, a Mg2+ channel involved in Salmonella virulence
12:20:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session I
18:00:00 Dinner
19:30:00 FOLDING AND LIPID-PROTEIN INTERACTIONS Kenton J Swartz
19:50:00 Discussion
20:00:00 Kv channels and the ribosome: tunnel vision Carol Deutsch
20:20:00 Discussion
20:30:00 Poster Contribution (TBA)
20:50:00 Discussion
21:00:00 Ion channel function and membrane phospholipids Zhe Lu
21:20:00 Discussion
Wednesday, March 5, 2008
07:30:00 Breakfast
09:00:00 VOLTAGE-GATED ION CHANNELS Mark L Mayer
09:00:00 Gating of potassium channels
09:20:00 Discussion
09:30:00 Principles underlying energetic coupling along an allosteric communication trajectory of a voltage-activated K+ channel Ofer Yifrach
09:50:00 Discussion
10:00:00 Coffee Break
10:30:00 Poster Contribution (TBA)
10:50:00 Discussion
11:00:00 Simulation Studies of Voltage Sensors: Interactions with Lipids and Water Mark Sansom
11:20:00 Discussion
11:30:00 Toxins interacting with paddle motifs in voltage-sensing proteins Kenton J Swartz
11:50:00 Discussion
12:00:00 Mechanism of Ca2+ decoding by the CaM/Ca channel complex David T Yue
12:20:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session II
18:00:00 Dinner
19:00:00 Business Meeting
19:30:00 NEW METHODS FOR STRUCTURAL ANALYSIS OF MEMBRANE PROTEINS Gebhard Schertler
19:30:00 Amphipol-mediated renaturation and immobilization of membrane proteins Jean Luc Popot
19:50:00 Discussion
20:00:00 Poster Contribution (TBA)
20:20:00 Discussion
20:30:00 Asymmetry and Ligand Sensitivity in Dimeric Associations of the Serotonin 5HT2c Receptor Filippo Mancia
20:50:00 Discussion
21:00:00 A generic methodology to stabilise GPCRs in detergent solution for structural studies Chris Tate
21:20:00 Discussion
Thursday, March 6, 2008
07:30:00 Breakfast
09:00:00 LIGAND RECOGNITION IN G-PROTEIN COUPLED RECEPTORS Reinhard Grisshammer
09:00:00 Does oligomerization of G protein-coupled receptors regulate coupling to G proteins? Roger Sunahara
09:20:00 Discussion
09:30:00 Structural studies of mGluR and related molecules Hisato Jingami
09:50:00 Discussion
10:00:00 Coffee Break
10:30:00 Crystal structure of squid rhodopsin Midori Murakami
10:50:00 Discussion
11:00:00 Poster Contribution (TBA)
11:20:00 Discussion
11:30:00 Structure of the Beta 1 Adrenergic Receptor: Progress in Obtaining Recombinant G Protein Coupled Receptor Structures Gebhard Schertler
11:50:00 Discussion
12:00:00 Structure and dynamics of the human beta 2 adrenergic receptor
12:20:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session II
18:00:00 Dinner
19:30:00 Structural Studies of the HIF Transporter Heather Pinkett
19:30:00 NUCLEOTIDE-COUPLED TRANSPORTERS Vinzenz M Unger
19:50:00 Discussion
20:00:00 Computer simulations of ABC transporters Peter Tieleman
20:20:00 Discussion
20:30:00 Poster Contribution (TBA)
20:50:00 Discussion
21:00:00 The structure, function and regulation of P-type ATPase pumps Poul Nissen
21:20:00 Discussion
Friday, March 7, 2008
07:30:00 Breakfast
09:00:00 Depart
4th Annual Pharma R&D Asia Congress
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