9th Annual Biomarkers Congress
MOLECULAR MECHANISMS IN LYMPHATIC FUNCTION & DISEASE
Four Points Sheraton / Holiday Inn Express

Ventura, , CA
http://www.grc.org/programs.aspx?year=2008&program=molecmech

Schedule of Presentations:

Sunday, March 2, 2008
16:00:00 Arrival and Check-in
18:00:00 Dinner
19:30:00 Welcome / Introductory Comments by GRC Site Staff
19:40:00 Growth factor and signaling pathways for lymphangiogenesis and tumor progression Kari Alitalo
19:40:00 GROWTH FACTOR MECHANISMS AND STEM CELLS IN LYMPHANGIOGENESIS Guillermo Oliver
20:10:00 Discussion
20:20:00 Molecular pathways mediating lymphatic vessel formation and differentiation Michael Detmar
20:45:00 Discussion
20:55:00 Dysfunctional and functional lymphangiogenesis during tumor progression Gou Young Koh
21:20:00 Discussion
Monday, March 3, 2008
07:30:00 Breakfast
08:30:00 Group Photo
09:00:00 TRANSCRIPTIONAL REGULATION OF ADIPOGENESIS AND LYMPHANGIOGENESIS Brant Weinstein
09:00:00 New directions in adipocyte development Evan Rosen
09:20:00 Discussion
09:30:00 Prox1 plays multiple roles in developmental and adult lymphangiogenesis Guillermo Oliver
09:50:00 Discussion
10:00:00 Coffee Break
10:30:00 Sox transcription factors and their role in lymphangiogenesis Peter Koopman
10:50:00 Discussion
11:00:00 Transcriptional regulation of lymphatic vascular maturation and remodeling Tatiana Petrova
11:20:00 Discussion
11:30:00 Transcriptional profiling of microvessels identifies molecules involved in leukocyte and cancer cell migration Dieter Maurer
11:50:00 Discussion
12:00:00 Successful culture isolation of bone marrow-derived lymphatic endothelial progenitor cells
12:10:00 Discussion
12:15:00 Forward-genetic screen in zebrafish for identifying lymphangiogenesis genes
12:25:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:30:00 Intravital Immunology: Initiation of immune responses to lymph-borne antigens
19:30:00 LYMPHATIC VASCULATURE IN IMMUNITY Dieter Maurer
19:55:00 Discussion
20:05:00 Dendritic cell migration to lymph nodes through lymphatic vessels Gwendalyn J Randolph
20:30:00 Discussion
20:40:00 Regulation of lymphatic endothelial transmigration David Jackson
21:05:00 Discussion
21:15:00 Inflamed lymphatic endothelium facilitates tumor metastasis via CCL-1/CCR8-dependent mechanism
21:25:00 Discussion
Tuesday, March 4, 2008
07:30:00 Breakfast
09:00:00 Differential regulation of the lymphatic proteome by VEGF receptors 2 and 3 Lena Claesson-Welsh
09:00:00 SIGNAL TRANSDUCTION, JUNCTIONS, AND CONTRACTILE PROTEINS IN LYMPHATICS Taija Mäkinen
09:20:00 Discussion
09:30:00 How blood shapes lymphatics Mark Kahn
09:50:00 Discussion
10:00:00 Coffee Break
10:30:00 Molecular and functional analysis of lymphangiogenic endothelial cells Hellmut G Augustin
10:50:00 Discussion
11:00:00 Specialized intercellular junctions in the endothelium of initial lymphatics Donald McDonald
11:20:00 Discussion
11:30:00 Unique contractile protein composition and contractile function of lymphatic vessels Michael J. Davis
11:50:00 Discussion
12:00:00 Adrenomedullin signaling is necessary for lymphatic vascular development
12:10:00 Discussion
12:15:00 Lymphotoxin in inflammation-induced lymphangiogenesis
12:25:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:30:00 LYMPHATIC VESSEL MORPHOGENESIS AND MATURATION David Jackson
19:30:00 Studying early lymphatic development using the zebrafish Brant Weinstein
19:50:00 Discussion
20:00:00 Microenvironmental properties for metastatic carcinoma cells in sentinel lymph node: with special reference to molecular profiling of human lymphatic endothelial cells interacted with the carcinoma cells Toshio Ohhashi, Yoshiko Kawai
20:20:00 Discussion
20:30:00 Axon guidance receptors in lymph/angiogenesis Anne Eichmann
20:50:00 Discussion
21:00:00 Mechanisms of lymphatic remodeling Taija Mäkinen
21:20:00 Discussion
Wednesday, March 5, 2008
07:30:00 Breakfast
09:00:00 LYMPHATIC METASTASIS Kari Alitalo
09:00:00 Intametastatic Carcinosis in Human Carcinomas: From Morphology to Mechanisms Dontscho Kerjaschki
09:20:00 Discussion
09:30:00 Activation of lymphangiogenic growth factors in cancer Marc Achen
09:50:00 Discussion
10:00:00 Coffee Break
10:30:00 Lymphangiogenesis and lymphatic letastasis - new insights from intravital microscopy
10:50:00 Discussion
11:00:00 Integrin regulation of lymphangiogenesis and tumor metastasis Judith Varner
11:20:00 Discussion
11:30:00 Role of inflamed lymphatic endothelium in cancer metastasis Mihaela Skobe
11:50:00 Discussion
12:00:00 Transcriptional profiling of tumor-derived lymphatic endothelial cells
12:10:00 Discussion
12:15:00 The role of Neuropilin-2 in tumor lymphangiogenesis Anil Bagri
12:25:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:00:00 Business Meeting
19:30:00 Functional-adaptive responses in lymphatic endothelium Melody Swartz
19:30:00 MOLECULAR CONTROL OF LYMPH TRANSPORT ACTIVITY David Bates
19:55:00 Discussion
20:05:00 The regulation of the real lymphatic function - lymph transport David Zawieja
20:30:00 Discussion
20:40:00 Hydraulic conductivity of human skin and subcutaneous tissue in normal and lymphedematous lower limbs Waldemar Olszewski
21:05:00 Discussion
21:15:00 Emilin1 deficiency causes structural and functional defects of lymphatic vasculature
21:25:00 Discussion
Thursday, March 6, 2008
07:30:00 Breakfast
09:00:00 Lymphatic targeting as a metastatic mechanism David Bates
09:00:00 GENETICS AND TREATMENT OF LYMPHATIC DISORDERS David Zawieja
09:20:00 Discussion
09:30:00 Etiology of lymph/vascular anomalies Miikka Vikkula
09:50:00 Discussion
10:00:00 Coffee Break
10:30:00 Refining the mechanisms for lymphatic failure in genotyped lymphoedema Peter Mortimer
10:50:00 Discussion
11:00:00 Reconstitution of collecting lymphatic vessels and sentinel lymph nodes with growth factor therapy Tuomas Tammela
11:20:00 Discussion
11:30:00 Molecular basis of nuchal edema in Down Syndrome fetus Young Kwon Hong
11:50:00 Discussion
12:00:00 Genetic studies of an autosomal recessive lymphedema-choanal atresia syndrome George A Diaz
12:20:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:30:00 THERAPEUTIC CHALLENGES IN LYMPHATIC DYSORDERS Mihaela Skobe
19:30:00 Lymphangiogenesis in Experimental Inflammatory Bowel Disease Jonathan Steven Alexander
20:00:00 Discussion
20:10:00 Therapeutic inhibition of tumor lymphangiogenesis: the promise and many vexing problems Bronek Pytowski
20:40:00 Discussion
20:50:00 Treatment of Lymphatic Dysfunction: State of the Art Stanley Rockson
21:20:00 Discussion
4th Annual Pharma R&D Asia Congress
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