Biotech China 2014
VIRAL VECTORS FOR GENE THERAPY, THE SCIENCE OF

Schedule of Presentations:

Sunday, March 2, 2008
16:00:00 Arrival and Check-in
18:00:00 Dinner
19:30:00 Welcome / Introductory Comments by GRC Site Staff
19:40:00 Immune Response to Viral Vectors Paul Robbins
19:50:00 Host Responses to Viral Vectors: The Final Frontier?
20:50:00 Discussion
Monday, March 3, 2008
07:30:00 Breakfast
09:00:00 Biodistribution and Targeting John Engelhardt
09:00:00 Clinical Update from Gene Therapy Trial for DMD R. Jude Samulski
09:30:00 Discussion
09:35:00 Ligand-Directed Vascular Targeting and Molecular Imaging Renata Pasqualini
10:05:00 Discussion
10:15:00 Group Photo
10:30:00 Coffee Break
11:00:00 Immune Cells as Carriers of Oncolytic Viruses to Treat Metastatic Tumours RG Vile
11:30:00 Discussion
11:45:00 Molecular Evolution of Novel Viral Gene Delivery Vehicles
12:15:00 Discussion
12:30:00 Lunch David V Schaffer
13:30:00 Free Time
16:00:00 Poster Session I
18:00:00 Dinner
19:30:00 Viral Entry and Nuclear Translocation
19:30:00 Endosomal Processing of rAAV2 John Engelhardt
19:50:00 Discussion
20:00:00 The Next Generation of Recombinant AAV Vectors Arun Srivastava
20:20:00 Discussion
20:30:00 Combining Gene Therapy and RNAi for treating human disease Mark A Kay
20:50:00 Discussion
21:00:00 Developing Viral Vectors for Phase I Cancer Trials: Manufacturing and Toxicology Challenges Anthony Welch
21:20:00 Discussion
Tuesday, March 4, 2008
07:30:00 Breakfast
09:00:00 The Innate Immune Response to Enveloped Virus Vectors Karen L Mossman
09:00:00 Host Cell Response to Viral Infection Joseph C Glorioso
09:30:00 Discussion
09:45:00 Antigen Presenting Cell Activation by Adenovirus Vectors Erik Falck-Pedersen
10:15:00 Discussion
10:30:00 Coffee Break
11:00:00 Innate Immune Responses Limit HSV Oncolysis Paola Grandi
11:30:00 Discussion
11:45:00 CMV encoded miRNAs
12:15:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session II
18:00:00 Dinner
19:30:00 The Innate Immune Response to DNA Daniel A Muruve
19:30:00 Innate Immune Response to Viral Infection James M Wilson
19:50:00 Discussion
20:00:00 Neutralization of Adenovirus by Naturally Occurring Antimicrobial Peptides Glen R Nemerow
20:20:00 Discussion
20:30:00 Innate Immune Response to Viral Vectors Yiping Yang
20:50:00 Discussion
21:00:00 Immunogenicity of AAV gene therapy vectors Sander van Deventer
21:20:00 Discussion
Wednesday, March 5, 2008
07:30:00 Breakfast
09:00:00 Adaptive Immune Response to Viral Infection Luigi Naldini
09:00:00 Adenovirus Interactions with the Innate and Adaptive Arms of the Immune System Andrea Amalfitano
09:25:00 Discussion
09:35:00 The Impact of T Cell Responses on the Safety and Efficacy of DNA Viral Vectors
10:00:00 Discussion
10:10:00 Coffee Break
10:40:00 Platelets Mediate Adaptive Immune Responses to Viral Vectors Luca G Guidotti
11:05:00 Discussion
11:15:00 The molecular and cell biology of T-cell mediated elimination of adenovirus transduced brain cells: implications for clinical gene therapy Pedro R Lowenstein
11:40:00 Discussion
11:50:00 Adaptive immune responses Abraham Scaria
12:15:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session (if needed)
18:00:00 Dinner
19:00:00 Business Meeting
19:30:00 Approaches to Blocking the Immune Response to Viral Infection Malcolm K Brenner
19:30:00 Modulating Lentiviral Vector Design to Escape Immune Response and Establish Stable Transgene Expression upon Systemic Delivery Luigi Naldini
19:50:00 Discussion
20:00:00 Immune Tolerance Induction to Therapeutic Proteins by Heptatic Gene Transfer Roland W Herzog
20:20:00 Discussion
20:30:00 Role of tolerogenic cells to modulate immune response to transgenes Maria Grazia Roncarolo
20:50:00 Discussion
21:00:00 Developing gene therapy approaches to induce immunological tolerance John Iacomini
21:20:00 Discussion
Thursday, March 6, 2008
07:30:00 Breakfast
09:00:00 Suppression of the Immune Response by Gene Transfer Maria Grazia Roncarolo
09:00:00 Treatment of autoimmune diseases using immunosuppressive DC-Derived Exosomes Paul Robbins
09:30:00 Discussion
09:45:00 Gene Therapy for Autoimmunity and Hemophilia: Role of B Cells as Tolerongenic Antigen Presenting Cells David Scott
10:15:00 Discussion
10:30:00 Coffee Break
11:00:00 DC’s Expressing IL-4 to Prevent and Possibly Treat T1D in NOD Mice Garrison Fathman
11:30:00 Discussion
11:45:00 Intra-articular delivery of an AAV vector for inflammatory joint disease: Comparison of preclinical and clinical studies Barrie J Carter
12:15:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session (if needed)
18:00:00 Dinner
19:30:00 Stimulation of the Immune Response by Gene Transfer Garrison Fathman
19:30:00 Lentiviral Vectors with Antisense HIV Payloads: Hitting the Target? Carl Henrik JUNE
19:50:00 Discussion
20:00:00 Gene Transfer to Harness the Immune Response Against Cancer Malcolm K Brenner
20:20:00 Discussion
20:30:00 Balancing Tumor Immunity and Inflammatory Pathology Glenn Dranoff
20:50:00 Discussion
21:00:00 Replication-Competent Adenovirus Vectors as Vehicles for HIV Vaccine Delivery Marjorie Robert-Guroff
21:20:00 Discussion
Friday, March 7, 2008
07:30:00 Breakfast
09:00:00 Departure
4th Annual Pharma R&D Asia Congress
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