9th Annual Biomarkers Congress
1st Immunogenicity: Determinants and Correlates Conference
THE HOTEL PROVIDENCE
139 Mathewson Street Providence, RI 02903
Providence, RI
http://www.epivax.com/blog/immunogenicity-determinants-and-correlates-2/
immunogenicity, vaccines, conferences May 11 (Wednesday) (TRIAD TOOLKIT and TREGITOPE MEETING)

Schedule of Presentations:

Monday, May 9, 2011
09:00:00 INTRODUCTIONS | Welcome Denice Spero
09:15:00 Introduction to the conference Orientation Michel Awwad
09:30:00 Session I | Determinants – Predicting Immunogenicity
09:35:00 Session introduction- Session Chairs and Panel Leaders | Brief mention of rationale for session and topics to be covered
09:45:00 The role of Complement in immunogenicity: Mechanism of Action, Toxicity and Hypersensitivity Christopher Horvath
10:10:00 Breaking tolerance | Innate Immunity and Danger Daniela Verthelyi
10:35:00 BREAK | Coffee in Poster Session Area
11:05:00 Aggregates | Td or not Td? Michel Awwad
11:35:00 Tolerance, Breach of Tolerance, Contribution of Tregs | Self vs Nonself, T-cell Epitopes David Scott
12:05:00 Role of Heterologous Immunity in Immune Response (Cross-reactive epitopes) Liisa Selin
12:30:00 LUNCH
13:30:00 Glycosylation, Sialation, DC-Sign
13:55:00 De-immunization (for better protein therapeutics) and De-tolerization (for better vaccine design) Lenny Moise
14:15:00 Panel discussion- Question and Answers- Panel Leaders | Role of Complement, innate immunity, T cells and B cells in the immune response to infection, vaccination, and protein therapeutics Terry Goletz, Eric Furfine
14:45:00 BREAK | Coffee | Tea in Poster Session Area
15:10:00 Session II | Correlates | Biomarkers and Model Systems
15:15:00 Session Introductions- Session Chair and Panel Leaders | Brief mention of rationale for session and topics to be covered David Scott, Michael Brehm
15:20:00 Animal Models that Correlate with Human Immune Response | HuSCID vs HLA Tg Michael Brehm
15:45:00 T effector Subsets, Tregs and T cell Assays: ELISpot, T cell Proliferation, FACS, T cell Subsets, Tregs Matt Baker
16:10:00 Artificial in vitro Immune Systems: InVitro ALN (artificial lymph node models, Matrix-based method) Don Drake
16:40:00 HLA as a biomarker – Putting the “personal” in vaccines and protein therapeutics Anne S. De Groot
17:00:00 Panel Discussion- Moderators
17:30:00 Networking Reception – in Poster Session Area
17:35:00 Dinner on Your Own – See Patrick Lowney | Karen Sorrento for Suggestions
18:00:00 Speaker Dinner
Tuesday, May 10, 2011
08:30:00 Lecture by Anne S. De Groot
08:55:00 Session III | Risk Mitigation | Preclinical Studies and Clinical Studies
09:00:00 Session Introduction | Session Chair and Panel Leaders Naren Chirmule, Michel Awwad
09:10:00 Preclinical Approaches, Clinical Proof or Principle Naren Chirmule
09:40:00 Deimmunization in Context
10:10:00 Immunosuppression | Role in Biotherapeutics
10:40:00 BREAK | POSTER SESSION
11:10:00 Japanese Regulatory Agency Perspective on Immunogenicity Shingo Niimi
11:30:00 FDA Perspective + New in vivo models Jack Ragreb
12:00:00 Panel Discussion | Lead by Panel Leaders Michel Awwad, Naren Chirmule
12:30:00 Lunch
13:25:00 Session IV | Case Studies
13:30:00 Opening Remarks | Moderators Anne S. De Groot, Michel Awwad
13:35:00 Open | Selected from Abstract submissions
14:00:00 Open | Selected from Abstract submissions
14:30:00 Adnectins Nick Marsh
15:00:00 BREAK | POSTER SESSION
15:30:00 Transplant and Tolerance Nader Najafian
16:00:00 Immunogenicity in Gene Therapy Vectors Federico Mingozzi
16:30:00 Panel Discussion Michel Awwad
16:45:00 Closing Remarks Anne S. De Groot, Michel Awwad
Wednesday, May 11, 2011
08:55:00 TRIAD TOOLKIT TRAINING to be held at URI PROVIDENCE CAMPUS
09:00:00 TRIAD TOOLKIT TRAINING : IVAX (Vaccines) and ISPRI (Protein Therapeutics) HANDS ON TRAINING
09:05:00 TRIAD TOOLKIT TRAINING Epitope Driven Vaccines – Recent History Anne S. De Groot
09:25:00 TREGITOPE MEETING
09:30:00 REGISTRATION and BREAKFAST
09:40:00 TRIAD TOOLKIT TRAINING Introduction to ‘IVAX’ TRIAD Vaccine Design Toolkit Matt Ardito, Bill Martin
09:45:00 WELCOME | TEA | COFFEE
10:00:00 Tregitope Overview | History | Status Anne S. De Groot
10:25:00 IMMUNOINFORMATICS TRIAD TOOLKIT TRAINING
10:25:00 ALTERNATIVE – TRIAD CMI CORE LAB TRAINING
10:30:00 Hands-On Lab Training
10:30:00 Hands-On Computer Training: T cell epitope prediction Conservation analysis & alignment, Vaccine Construction Eric Gustafson, Matt Ardito, Frances Terry
10:30:00 Tregitopes | Mechanisms and Delivery Leslie Cousens
11:10:00 Alloimmunity and Transplant Tolerance Nader Najafian
11:50:00 Modulation of AAV vectors immunogenicity Federico Mingozzi
12:30:00 JOINT LUNCH with TREGITOPE MEETING
12:30:00 LUNCH BREAK | LUNCH POSTER SESSION- WITH TRIAD | Joint Lunch with TRIAD Toolkit Participants
13:30:00 Tregitopes, Th17 and EAE Samia Khoury, Wassim Elyaman
14:00:00 INSERM UMRS 872 (ex-INSERM U681) Equipe 16 ” Immunopathology and therapeutic immunointervention” Centre de Recherche des Cordeliers Louis Pasteur
14:30:00 GROUP DISCUSSIONS Anne S. De Groot
15:00:00 CLOSING REMARKS | END OF PUBLIC MEETING
15:30:00 Closed meeting of Tregitope Collaborators | Future Direction of Research
4th Annual Pharma R&D Asia Congress
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