3D Tissue Models

New York, NY

Schedule of Presentations:

Sunday, May 4, 2008
16:00:00 Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm)
18:00:00 Dinner
19:30:00 Introductory Comments by GRC Site Staff / Welcome: Peter Brophy
20:00:00 Keynote Lecture
20:00:00 Introduction Wendy B. Macklin
20:15:00 Myelination and Demyelination: Progress, and Major Unsolved Questions David Colman
21:15:00 Discussion
Monday, May 5, 2008
07:30:00 Breakfast
09:00:00 Junctional complexes, axo-glial interactions and assembly of the node of Ranvier
09:00:00 Discussion Ori Peles
09:00:00 Introductory Remarks
09:10:00 Sodium channel beta subunits: roles in channel modulation and axo-glial communication Lori L Isom
09:30:00 Mechanisms of CNS node of Ranvier formation
09:50:00 Genetic analysis of myelination in zebrafish Will Talbot
10:10:00 Discussion
10:30:00 Group Photo / Coffee Break
11:15:00 Commentary and Discussion Ori Peles
11:30:00 Moving Beyond Axon Guidance: Netrin Function During Oligodendrocyte Maturation and Myelination Tim Kennedy
11:50:00 Connexins in Myelinating Glia Charles Abrams
12:10:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
17:30:00 Peripheral neuropathies: lessons for Schwann cell biology
17:30:00 Discussion Kristjan R Jessen, Dies Meijer
17:30:00 Introductory remarks
17:40:00 Concepts learned from disease mechanisms in inherited peripheral neuropathies Ueli Suter
18:00:00 Glycolipid targets for inflammatory injury to Schwann cells in human autoimmune neuropathies Hugh Willison
18:20:00 Commentary and Discussion Dies Meijer
18:30:00 New roles for dystroglycan in myelination LAURA FELTRI
18:50:00 Regulation of PNS myelination by integrin-linked-kinase (ILK) and associated molecules Joao Relvas
19:10:00 Discussion
20:00:00 Dinner
21:30:00 Poster Session
Tuesday, May 6, 2008
07:30:00 Breakfast
09:00:00 Discussion Nancy Ratner, Jim Salzer
09:00:00 Introductory remarks Nancy Ratner
09:00:00 Signaling and transcriptional regulation in developing myelinating glia
09:10:00 Receptor tyrosine kinase signaling that regulates myelination Haesun Kim
09:30:00 Schwann cell SCAP and SREBP are required for proper myelination Mark Verheijen
09:50:00 The fate of NG2 cells Akiko Nishiyama
10:00:00 Lineage analysis and genetic manipulation of glia cells in health and disease Leda Dimou
10:10:00 Discussion
10:30:00 Coffee Break
10:50:00 Commentary and Discussion Jim Salzer
11:00:00 Transcriptional Regulation of Myelination Jeff Milbrandt
11:20:00 Unwrapping the role of Sox proteins in myelination Michael Wegner
11:40:00 Post-translational regulation of olig2 function in oligodendrocyte development
12:00:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
17:30:00 Introductory remarks David Rowitch
17:30:00 White matter diseases: lessons for MS?
17:30:00 Discussion David Rowitch
17:40:00 CNS demyelination in CMT1X patients and in gap junction mutant mice Kleopas A. Kleopa
18:00:00 A role for the oligodendrocyte in supporting the axon: Implications for the demyelinated axon? Julia Edgar
18:20:00 Commentary and Discussion
18:30:00 Genes involved in leukodystrophies: a glance at glial functions Odile Boespflug-Tanguy
18:50:00 Microglial involvement in motor neuron degeneration in models of ALS
19:10:00 Discussion
20:00:00 Dinner
21:30:00 Poster Session
Wednesday, May 7, 2008
07:30:00 Breakfast
09:00:00 Introductory remarks Marie T. Filbin
09:00:00 Repair and regeneration in vivo
09:00:00 Discussion Marie T. Filbin, Anne Baron-Van Evercooren
09:10:00 Imaging neuro-glial pathology in vivo Martin Kerschensteiner
09:30:00 In vivo imaging and genetic analysis of axon wrapping by oligodendrocytes Bruce H. Appel
09:50:00 Novel transplantation strategies to repair the injured spinal cord Mary Bartlett Bunge
10:10:00 Discussion
10:30:00 Coffee Break
10:50:00 Commentary and Discussion Anne Baron-Van Evercooren
11:00:00 Myelin Semaphorins
11:20:00 Inhibition of scarring and neuroprotective intervention to promote spinal cord repair
11:40:00 Novel approaches for the treatment of MS - moving beyond immunomodulation Frank Walsh
12:00:00 Discussion Leanne Rivers
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
17:30:00 Discussion Klaus-Armin Nave
17:30:00 Introductory remarks
17:30:00 Extracellular signaling and myelination in CNS and PNS
17:40:00 Regulation of myelination by Neuregulin 1 Carla Taveggia
18:00:00 Regulation of cholesterol biosynthesis in Schwann cells by NRG1 Hugo Cabedo
18:20:00 Commentary and Discussion Klaus-Armin Nave
18:30:00 Strength in numbers: Working together to promote oligodendrocyte differentiation Jonah Chan
18:50:00 Thinking outside the cell: How extracellular matrix molecules influence oligodendrocyte development Holly Colognato
19:30:00 Business Meeting
20:00:00 Dinner
21:30:00 Poster Session
Thursday, May 8, 2008
07:30:00 Breakfast
09:00:00 Introductory remarks Larry Wrabetz
09:00:00 Glial cell death and axonal pathology
09:00:00 Discussion Larry Wrabetz, David Attwell
09:05:00 The Unfolded Protein Response: To live or to die? Randal J. Kaufman
09:25:00 The unfolded protein response in vivo Alex Gow
09:35:00 ER stress modulates the response of oligodendrocytes to inflammation BRIAN POPKO
09:55:00 Intermittent fasting diet enhances protein homeostatic mechanisms and improves motor performance of hereditary neuropathic mice Lucia Notterpek
10:10:00 Discussion
10:30:00 Coffee Break
10:50:00 Commentary and Discussion David Attwell
11:00:00 Myelinating glia and regulation of axonal transport Scott Brady
11:20:00 Neurotransmitter signalling to oligodendrocytes and their precursors
11:40:00 Vesicular release of glutamate along the axons: a new form of fast signalling from neurons to oligodendroglial cells in white matter Maria Kukley
12:00:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
17:30:00 Discussion Robin E. Franklin, Richard Reynolds
17:30:00 Animal models of demyelination: have we learned anything useful?
17:30:00 Introductory remarks Robin E. Franklin
17:40:00 Myelin damage and repair in multiple sclerosis and experimental models: new insights Christine Stadelmann
18:00:00 CNS myelin mutants; what have they told us about myelination and human disease Ian D. Duncan
18:20:00 Commentary and Discussion Richard Reynolds
18:30:00 Targeting of neuronal protection pathways in transgenic mice and its effect upon CNS myelination Lesley Probert
18:50:00 Regulatory APC that modulate T cell-mediated CNS autoimmunity Scott S. Zamvil
19:10:00 Discussion
20:00:00 Dinner
Friday, May 9, 2008
07:30:00 Breakfast
09:00:00 Depart
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