Biotech China 2014
Gordon Research Conference: Protein Folding Dynamics
Hotel Galvez

Galveston, TX USA
http://www.grc.org/programs.aspx?year=2014&program=protfold
Gordon Research Conference: Protein Folding Dynamics
GRC
http://www.grc.org/programs.aspx?year=2014&program=protfold
Hotel Galvez
Galveston
TX USA

Schedule of Presentations:

Sunday, January 5, 2014
09:15:00 Discussion
14:00:00 Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm)
18:00:00 Dinner
19:30:00 Welcome / Introductory Comments by GRC Site Staff
19:40:00 Current Discoveries in Experimental and Theoretical Analysis of Protein Folding Dynamics Jane Clarke
19:40:00 Seeing the Invisible by Solution NMR Spectroscopy Lewis Kay
20:20:00 Discussion
20:35:00 Simulations of Protein Folding and Dynamics - What is Missing? Angel Garcia
Monday, January 6, 2014
07:30:00 Breakfast
08:05:00 Discussion
08:15:00 Cis and Trans Modulation of Polyglutamine Aggregatio Rohit Pappu
08:30:00 Group Photo
09:00:00 Mechanisms of Protein Folding and Assembly
09:00:00 Discussion Leader: Ben Schuler (University of Zurich) "Introduction"
09:10:00 Stefano Piana (D. E. Shaw Research) "Equilibrium Simulations of Slow and Fast Folding Proteins" Stefano Piana
09:15:00 Discussion
09:35:00 Discussion
09:45:00 TBA
09:55:00 Discussion
10:00:00 Coffee Break
10:30:00 Simulating Protein Folding on the Millisecond Timescale Vijay Pande
10:55:00 Discussion
11:05:00 Long-Range Interactions in Globally Unfolded Proteins Mikael Oliveberg
11:30:00 Discussion
11:40:00 Connections Between the Energy Landscapes for Folding, Allostery and Virus Capsid Formation Neil Ferguson
12:05:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:30:00 Discussion Leader: Joan Emma Shea (University of California, Santa Barbara) "Introduction"
19:30:00 Errors of Protein Folding
19:40:00 Interface-Triggered Formation of Functional Amyloid by Hydrophobin Proteins Margaret Sunde
20:40:00 Discussion
20:50:00 The Accessible Conformations of N-terminal Acetylated α-Synuclein: Implications for Aggregation Jean Baum 
Tuesday, January 7, 2014
06:00:00 New Presentation
07:30:00 Breakfast
09:00:00 Discussion Leader: Lila Gierasch (University of Massachusetts Amherst) "Introduction" Lila Gierasch
09:00:00 Folding in the Cell
09:10:00 Co-Translational Folding of Membrane Proteins Gunnar von Heijne
09:35:00 Discussion
09:45:00 TBA
09:55:00 Discussion
10:00:00 Coffee Break
10:30:00 Physical Limits and Heterogeneity in Cells and Proteomes: Model Prediction using Protein Knowledge Bases
10:55:00 Discussion
11:05:00 Folding Proteins from One End to the Other
11:30:00 Discussion
11:40:00 Folding: in silico - in vitro - in vivo Martin Gruebele 
12:05:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:30:00 Discussion Leader: Susan Marqusee (University of California, Berkeley) Susan Marqusee
19:30:00 Membrane Protein Folding
19:40:00 Towards a Complete Description of the Folding Mechanism of the Integral Membrane Protein, GlpG Daniel Otzen 
20:15:00 Membrane Protein/Protein and Protein/Lipid Interactions Probed via Multiscale MD Simulations Mark Sansom
20:40:00 Discussion
20:50:00 Molecular Pathologies of CF-causing Mutations and Mechanisms of Membrane Protein Folding
21:15:00 Discussion
Wednesday, January 8, 2014
06:00:00 New Presentation
07:30:00 Breakfast
09:00:00 Protein Dynamics and Function
09:00:00 Discussion Leader: Peter Tompa (Free University of Brussels) "Introduction" Peter Tompa
09:10:00 Separated at Birth, the Evolution of Protein Dynamics over a Billion Years Dorothee Kern
09:35:00 Discussion
09:45:00 TBA
10:00:00 Coffee Break
10:30:00 Dynamics of Folded and Partly Folded Proteins Jane Dyson
10:55:00 Discussion
11:05:00 Functional Dynamics of Disordered Regions in Multi-Domain Proteins Shoji Takada
11:30:00 Discussion
11:40:00 Towards a Theoretical Description of Function of a Molecular Motor Dave Thirumalai 
12:05:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:00:00 Business Meeting
19:30:00 Discussion Leader: David Brockwell (University of Leeds) "Introduction" David Brockwell
19:30:00 Forced Unfolding Dynamics
19:40:00 Single Molecule Mechanics and Dynamics of Protein Folding Matthias Rief
20:05:00 Discussion
20:15:00 Simultaneous Measurement of Motor Protein Conformation and Activity with Optical Traps and Fluorescence Microscopy Yann Chemla
20:40:00 Discussion
20:50:00 (ETHl, Zurich) "Forced unfolding, Refolding and Misfolding of Single Beta-barrel Proteins into Lipid Membranes Daniel Müller
21:15:00 Discussion
21:55:00 Discussion
Thursday, January 9, 2014
06:00:00 New Presentation
06:00:00 New Presentation
06:00:00 New Presentation
07:30:00 Breakfast
09:00:00 Protein Design and Evolution
09:00:00 Discussion Leaders: TJ Lane (Stanford University) and Adrian Nickson (University of Cambridge) "Introduction" TJ Lane
09:10:00 Linking Protein Folding to Biology, One Mutation at a Time Eugene Shaknovitch
09:35:00 Discussion
09:45:00 TBA
09:55:00 Discussion
10:00:00 Coffee Break
10:30:00 Driving Protein Folding and Dynamics Through the Lens of Natural Selection Yousif Shamoo
10:55:00 Discussion
11:05:00 Probing the Interplay of the Folding and Functional Energy Landscapes of Designer Cytokines Pat Jennings
11:30:00 Discussion
11:40:00 Molecular Design and Functional Specificity - from Proteins to Cells Tanja Kortemme
12:05:00 Discussion
12:30:00 Lunch
13:30:00 Free Time
16:00:00 Poster Session
18:00:00 Dinner
19:30:00 Breakfast
19:30:00 Protein Folding: Outlook and Challenges Ahead
19:30:00 Discussion Leader: Jose Onuchic (Rice University) "Introduction Jose Onuchic
19:40:00 Structural Intermediates in the Early Assembly of the Ribosomal Small Subunit Zan Luthey-Schulten
20:05:00 Discussion
20:15:00 From Studying Protein Folding and Misfolding in vitro to Studying Folding and Misfolding in Living Organisms
20:40:00 Discussion
20:50:00 Merging Experiment, Theory and Simulation in Studies of Complex Folding Processes Charlie Brooks 
21:00:00 Departure
21:15:00 Discussion
Friday, January 10, 2014
4th Annual Pharma R&D Asia Congress
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