3D Tissue Models
Cellular Signalling and Cancer Therapy
Cavtat-Dubrovnik, Dubrovnik
Cellular Signalling and Cancer Therapy 

Schedule of Presentations:

Friday, May 23, 2014
16:00:00 Arrival and registration
18:00:00 Welcome words Ivan Dikic
18:00:00 Keynote Lecture 1 Seven Transmembrane Receptors
19:30:00 Keynote lecture 3 – in Memory of Tony Pawson Guiding Signals through Anchored Enzyme Complexes John Scott
20:00:00 Welcome Dinner
20:50:00 Keynote Lecture 2: Receptor Tyrosine Kinases; Mechanism of Activation and Cancer Therapy
Saturday, May 24, 2014
09:00:00 Keynote lecture 4: Targeting K-Ras driven tumors Mariano Barbacid
09:40:00 Tyrosine kinase signalling networks in human cancer Roger Daly
10:15:00 Ubiquitin dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by IAPs
10:40:00 Tea Break
11:15:00 Novel targets of Raf in tumorigenesis Manuela Baccarini
11:45:00 BRAF and RAS signalling in melanoma: basic biology and therapeutic options Richard Marais
12:20:00 Selected talk 1
12:30:00 Selected talk 2
12:40:00 Selected talk 3
13:00:00 Lunch Break
14:30:00 Keynote lecture 5: Harnessing Genetic Dependencies in Cancer Therapy Alan Ashworth
15:10:00 Histidine phosphorylation: the invisible phosphoproteome? Tony Hunter
15:45:00 Comprehensive genomic analysis of human tumors identifies oncogenic drivers
16:10:00 Tea Break
16:40:00 Control of DNA repair activity at mammalian telomeres
17:15:00 Signalling a cell cycle exit after radiation therapy René H Medema
17:50:00 Selected talk 4
18:00:00 Selected talk 5
18:10:00 Selected talk 6
19:00:00 Poster session (odd numbers)
Sunday, May 25, 2014
09:00:00 Keynote lecture 5: Survival and Vascular Co-option of Metastasis Initiating Cells
09:40:00 Focal adhesion kinase signalling and cancer immune evasion Margaret Frame
10:20:00 Targeting Signal Transduction for the Treatment of Acute Myeloid Leukemia Hubert Serve
10:40:00 Tea Break
11:10:00 Rap signalling complexes: landmark recognizing modules in cell adhesion and polarity Hans Bos
11:45:00 Tumor Suppressor role for the deubiquitinase, BAP1 Vishva Dixit
12:20:00 Selected talk 7
12:30:00 Selected talk 8
13:00:00 Poster session (even numbers)
15:15:00 Excursion (Dinner not included)
Monday, May 26, 2014
09:00:00 Keynote lecture 7: Regnase-1-mediated regulation of the immune response Shizuo Akira
09:40:00 IKK/NF-kB signalling in inflammation and cancer Manolis Pasparakis
10:15:00 Tea Break
10:15:00 Targeting Inflammatory Cytokines and Chemokines Frances R. Balkwill
11:20:00 The EGFR - exploring the unexpected Maria Sibilia
11:55:00 A Numb/p53 circuitry couples control of replicative self-renewal and tumour suppression in normal and cancer mammary epithelial cells Pier Paolo Di Fiore
12:30:00 Molecular basis for engineering myeloid suppressors Peter Murray
13:05:00 Lunch
14:30:00 Keynote lecture 7: Signalling in wound-induced skin cancer Fiona Watt
15:10:00 Anaplastic Lymphoma Kinase signalling in Drosophila and mouse models Ruth Palmer
15:45:00 Tea Break
16:15:00 Structural regulation of ubiquitin pathways Brenda Schulman
16:50:00 Mitotic Wnt signaling regulates cell growth and proliferation Christof Niehrs
17:25:00 The function of p63 and p73 in genetic quality control and cancer development Volker Dötsch
18:00:00 Poster session (even numbers)
20:30:00 Farewell dinner and dancing
Tuesday, May 27, 2014
06:00:00 New Presentation
06:00:00 New Presentation
06:00:00 New Presentation
06:00:00 New Presentation
06:00:00 New Presentation
06:00:00 New Presentation
09:00:00 Keynote Lecture 9: Life and Death Decisions: Annexin AI expressed on apoptotic cells downregulates the immune response Peter Krammer
09:40:00 Caspase-2 as a tumour suppressor Sharad Kumar
10:15:00 Selected talk 9
10:25:00 Selected talk 10
10:35:00 Tea Break
11:05:00 Keynote lecture 10: Autophagy in cancer Yoshinori Ohsumi
11:45:00 Autophagy in haematological tumors Katharina Simon
12:20:00 Autophagy: Friend or foe in the treatment of fusion protein-associated leukemias?
12:55:00 Poster award ceremony and closing remarks
13:15:00 Lunch break
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