3D Tissue Models
Epigenetics in Drug Discovery
Buckingham House
Murray Edwards College Huntingdon Road
Cambridge CB3 0DF, United Kingdom
SELECTBIO is pleased to announce Epigenetics in Drug Discovery 2016, which will be held on 26 - 27 January 2016 in Cambridge, UK. The event is part of our Cambridge Workshop Series. 

Attracting researchers, academics and industry professionals working in epigenetic research, this event will explore the potential of epigenetics to contribute towards novel and existing therapeutics, across significant areas of unmet need. Emerging technologies, epigenetic changes and cellular reprogramming will also be discussed, with special attention paid to drug discovery and development. 

Viewed as a new frontier in drug discovery, rapid progress has been made in our understanding of epigenetic mechanisms of both new and existing drugs. With the processes that control epigenomic function providing new opportunities, epigenetics targets are enabling the discovery of novel drugs. 

If you work in drug discovery research you will benefit from the expert knowledge of academic and industry leaders who are pushing the boundaries of epigenetics research, whilst networking with the technology providers who are enabling them to do so. 

Schedule of Presentations:

Tuesday, January 26, 2016
08:00:00 Registration
09:00:00 Session Sponsor | Chemical Probes for Epigenetic Targets Susanne Muller Knapp
09:45:00 Session Sponsor | Keynote Presentation Epigenetics Drug-discovery: From Target to Patients with BET Bromodomain Inhibitors Rabinder Prinjha
10:30:00 Targeting on Epigenetic Proteins for Cancer Therapy Jun Qi
11:00:00 Coffee and Networking in Exhibition Hall
11:30:00 Application of Super-enhancer Analysis for Drug Discovery
12:00:00 Assays and Inhibitors for Targeting the Histone Methylome Manfred Jung
12:30:00 Technology Spotlight: Diagenode Technologies for Epigenetic Research and NGS Applications
12:35:00 Lunch & Networking in Exhibition Hall
14:15:00 Technology Spotlight: Tools For Epigenetic Target Based Drug Discovery – Assays For Methyltranferase/Demethylase Activity And Histone Binding By NanoBRET Technology
15:00:00 Noncoding RNA Ensembles Underlying Neuronal Function Marc Muskavitch
15:30:00 Targeting Histone H3K36me3-deficient Cancers Tim Humphrey
16:00:00 Coffee and Networking in Exhibition Hall
16:30:00 Resistance Mechanism to EZH2 Inhibitor Ho Man Chan
17:00:00 Epigenetic Enzymes Regulating Macrophage Function and Inflammatory Responses Menno de Winther
17:30:00 End of Day One
Wednesday, January 27, 2016
09:00:00 Structure-based Development of Inhibitors for Epigenetic Targets Takashi Umehara
09:30:00 Plenary Presentation : The Emerging Translational Landscape for EPZ-6438, A Small Molecule Inhibitor of EZH2
10:15:00 Targeting DNA Methylation in Treatment of Behavioural and Mental Disorders; Lessons from Cancer Dr. Moshe Szyf
10:45:00 Coffee and Networking in Exhibition Hall
11:15:00 Advances in the Development of KDM1A Inhibitors for Oncology and Neurodegeneration Tamara Maes
11:45:00 Chemogenomic Approaches to Spatiotemporal Regulation of HDAC Activity Ralph Mazitschek
12:15:00 Lunch & Networking in Exhibition Hall
13:45:00 Technology Spotlight
14:00:00 Playing the System: Finding Inhibitors of Epigenetic Target Families Paul Bamborough
14:30:00 HDAC6 Inhibition: Getting Microtubule Transport Back on Track Matthew Jarpe
15:00:00 Coffee and Networking in Exhibition Hall
15:30:00 Targeting Epigenetic Reader Domains with Medicinal Chemistry and Chemical Biology
16:00:00 Follicular Lymphoma An Epigenetic Addicted Cancer Jude Fitzgibbon
16:30:00 Close of Conference
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