3D Tissue Models
2nd Protease Inhibitors in Drug Discovery Conference
San Diego Marriott La Jolla
4240 La Jolla Village
San Diego, United States
2nd Protease Inhibitors in Drug Discovery Conference
Global Technology Community
San Diego Marriott La Jolla
4240 La Jolla Village
San Diego
United States

Schedule of Presentations:

Tuesday, March 1, 2016
06:00:00 New Presentation
12:00:00 Registration & Continental Breakfast
12:15:00 Keynote Presentation Matthew Bogyo
13:25:00 Welcome & Opening Remarks
13:30:00 2nd Protease Inhibitors in Drug Discovery Conference Charles Craik
15:00:00 Keynote Presentation
15:45:00 Afternoon Networking Break
16:15:00 The Sister Proteases DPP4 and Fibroblast Activation Protein As Biomarkers and as Therapeutic Targets in Steatosis and Fibrosis Mark Gorrell
16:45:00 A Novel, Structure and Mechanism Based Modular Route to Inhibitors of Rhomboid Intramembrane Proteases Kvido Strisovsky
17:15:00 Evening Reception & Poster Session
Wednesday, March 2, 2016
06:00:00 New Presentation
06:00:00 New Presentation
07:00:00 Continental Breakfast
08:00:00 Discovery of Verubecestat (MK-8931): A Beta-secretase Inhibitor in Phase 3 Clinical Development for Alzheimer’s Disease
08:25:00 Discovery and Development of a Protease Inhibitor for Chagas Disease James McKerrow
08:50:00 Daniel Bachovchin Daniel Bachovchin
09:15:00 Can We Replace Chemotherapy with Protease Inhibitors? James Janetka
09:40:00 Oral Presentations from Exemplary Submitted Abstracts
10:05:00 Morning Networking Break
10:45:00 Evolved Caspases for Exosite Identification Jeanne Hardy
11:10:00 Judith Clements Judith Clements
11:35:00 Structure and Inhibition of the Contact System Proteases Jonas Emsley
12:00:00 Lunch Provided by GTCbio
13:00:00 Cysteine Protease Cathepsin K in Autoimmune Systemic Lupus Erythematosus
13:25:00 Ectosteric or Allosteric Inhibition of Proteases? Dieter Brömme
13:50:00 Steven Wagner Steven Wagner
14:15:00 The Retropepsin-like Enzyme RC1339/APRc from Rickettsiae as a Potential Therapeutic Target for Rickettsial Diseases Isaura Simoes
14:40:00 Afternoon Networking Break
15:25:00 Activity-specific Inhibition of Legumain as a Target in Neurodegeneration Johann Brandstetter
15:50:00 Catherine Abbott Catherine Abbott
16:15:00 Novel Intracellular Roles of MMP12 in Breast Cancer That Will Make You Syk Antoine Dufour
16:40:00 The Challenge of Finding Inhibitory Antibodies Against the Trimeric Serine Protease HtrA1 for Treatment of Ocular Disease Daniel Kirchhofer
17:05:00 Global and Unbiased Detection of Proteolytic Activity in Infectious Organisms: A Rapid Approach to Identify Key Proteases for Drug Development
17:30:00 Closing Remarks & Conference Concludes
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