9th Annual Biomarkers Congress
Kinase Inhibitors
World Trade Center
200 Seaport Boulevard
Boston, MA
http://www.healthtech.com/dot/kit.aspx?&c=494

Schedule of Presentations:

Tuesday, October 21, 2008
07:00:00 Registration Open
07:30:00 Morning Coffee
08:30:00 Chairperson’s Remarks
08:40:00 Dissecting Kinase Inhibitor Activities by Genome-Wide Dose Response Analysis Rui-Ru Ji
09:10:00 Discovery of MP-529: A Selective Inhibitor of Aurora 2 Kinase in Development for the Treatment of Cancer Hariprasad Vankayalapati
09:40:00 Clinical Experiences with a Selective, Orally Bioavailable MET Receptor Tyrosine Kinase Inhibitor for Targeted Treatment of Human Cancers Stephen K. Burley
10:10:00 Grand Opening Coffee Break in the Exhibit Hall
10:40:00 The Role of Biomarkers in Kinase Inhibitor Development: Pharmacodynamic and Predictive Clinical Studies Jason Hill
11:10:00 Talk Title to Be Announced John Hynes
11:40:00 Profiling Kinases Directly in Human Tissues with KinobeadsTM David Simmons
12:10:00 Panel Discussion: Do We Need More Targets?
12:40:00 Luncheon Technology Workshop or Lunch on your Own
13:40:00 Session Break
14:20:00 Chairperson’s Remarks Ariel Fernandez
14:25:00 Structure-Guided Design of Inhibitors of Key Bcr-Abl Point Mutations which Confer Resistance to Imatinib William Shakespeare
14:55:00 Translational Ideas to Curb Side Effects in Anticancer Kinase-Targeting Therapy: Reducing Cardiotoxicity through Inhibitor Redesign Ariel Fernandez
15:25:00 Technology Watch (Sponsorship Available)
15:55:00 Networking Refreshment Break in the Exhibit Hall
16:30:00 Targeting the BDNF/TrkB Signal Transduction Pathway; Lessons Learned from Studies on Neuroblastoma Tumors Carol J Thiele
17:00:00 ex vivo Model of Drug Screening, Toxicology, and Tailored Medicine Masato Mitsuhashi
17:30:00 in vivo Genetic Approaches to Identify Mechanisms of Resistance to Inhibition of ErbB-family Receptor Tyrosine Kinases Ronan O’Hagan
18:00:00 Happy Hour in the Exhibit Hall
19:30:00 End of Day
Wednesday, October 22, 2008
07:00:00 Registration Open
07:30:00 Breakout Discussion Sessions
08:30:00 Chairperson’s Remarks Ronan O’Hagan
08:40:00 Targeting the PI3K Pathway in Lung Disease Matt Thomas
09:10:00 Focusing on PK Inhibitors as Potential Antimalarial Drugs Didier Leroy
09:40:00 Networking Coffee Break in the Exhibit Hall
10:40:00 The Discovery of Potent Selective JAK2 Inhibitors for Treatment of Myeloproliferative Disorders Chris Burns
11:10:00 NVP-AEB071: Oral and Specific Inhibitor of PKC for the Prevention of Graft Rejection and the Treatment of Autoimmune Diseases Jürgen Wagner
11:40:00 Protein Kinases as Potential Targets in CNS Diseases Leona Ling
12:10:00 Targeting Protein Kinases in CNS Disorders D Martin Watterson
12:40:00 Close of Kinase Inhibitors Conference
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