| Monday, November 17, 2008 | ||
| 12:00:00 | Main Conference Registration | |
| 12:30:00 | Chairperson’s Welcoming Remarks | Robert E Hughes |
| 13:40:00 | Process Development of Eribulin Mesylate (E7389), a Halichondrin B Inspired Breast Cancer Therapy | Bryan Lewis |
| 14:10:00 | Large-Scale Synthesis of Discodermolide, a Marine Natural Product for the Treatment of Advanced Solid Tumors | Frederick Kinder |
| 14:40:00 | Route Selection and Process Development for the Synthesis of Flt-3 Kinase Inhibitors for Cancer Therapeutics | Wen-Chung Shieh |
| 15:10:00 | APIs: Simplicity by Design. A Low-Tech Approach for Quality and Profitability | Girish Malhotra |
| 15:40:00 | Networking Refreshment Break, Poster and Exhibit Viewing | |
| 16:15:00 | Roundtable/Break-Out Session Topics | |
| 17:15:00 | Networking Reception | |
| 18:00:00 | End of Day | |
| Tuesday, November 18, 2008 | ||
| 08:00:00 | Morning Coffee | |
| 08:30:00 | Chairperson’s Remarks | Neal G. Anderson |
| 08:40:00 | Innovations in Micro-Flow Reactors for Continuous Processing | Klavs Jensen |
| 09:10:00 | PAT Applications for Scale-up Synthesis: Comparing On-line HPLC and In-line IR | Andrew Lange |
| 09:40:00 | A Fast and Efficient Way to Measure Drug Form Optimization and Production with Near Infra-Red and Infra-Red-Based Imaging | Weiyong Li |
| 10:10:00 | Networking Refreshment Break, Poster and Exhibit Viewing | |
| 10:45:00 | Chairperson’s Remarks | |
| 10:55:00 | Control Strategy in a Quality by Design (QbD) Environment | Stephen Liebowitz |
| 11:30:00 | Does Your Process Achieve QbD? A Statistical Model Can Predict ‘Critical Quality Attributes’ | Bir Gujral |
| 12:00:00 | Luncheon Technology Workshop | |
| 13:30:00 | Chairperson’s Remarks | |
| 13:35:00 | Genotoxic Impurities in Pharmaceuticals: A Regulatory Perspective | David Ziering |
| 14:10:00 | Genotoxic Impurities: Hazard Identification and Safety Considerations during Drug Development | Krista Dobo |
| 14:40:00 | Networking Refreshment Break, Poster and Exhibit Viewing | |
| 15:15:00 | Chairperson’s Remarks | |
| 15:20:00 | Integrating Biocatalysis and Process Chemistry: Challenges and Success Stories | Alex Tao |
| 15:50:00 | Reducing the Initial Time Lag from Incorporating Biocatalysis into Process Development | |
| 16:20:00 | Engineering Effective Biocatalysts | Romas Kazlauskas |
| 16:50:00 | Shared Presentation: Green Manufacturing of Pharmaceuticals Using Custom-Evolved Biocatalyst | Jim LaLonde |
| 17:35:00 | End of Day | |
| Wednesday, November 19, 2008 | ||
| 08:00:00 | Morning Coffee | |
| 08:30:00 | Chairperson’s Remarks | Orn Almarsson |
| 08:35:00 | Supercritical Fluid Chromatography (SFC) as an Isolation Tool for By-Product and Impurity Identification | |
| 09:05:00 | Case Studies of Analytical Challenges in API Process Research & Development | |
| 09:40:00 | Networking Coffee Break, Poster and Exhibit Viewing | |
| 10:15:00 | Pharmaceutical Co-Crystals: History and Relevance to Drug Development | Orn Almarsson |
| 10:45:00 | Scaling-Up Co-Crystal Crystallizations | Renato Chiarella |
| 11:15:00 | Close of Conference | |
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