| Sunday, December 7, 2008 | ||
| 12:00:00 | Registration (Randle Foyer) | |
| 13:00:00 | "Special Interest Groups Session I" | |
| 13:00:00 | SIG 1: Extracellular Matrix-Driven Regulation of Innate Immune Response and Inflammation (Cunningham A) | Aravinda Chakravarti, Liliana Schaefer; |
| 13:05:00 | SIG 1: Biglycan and Toll-like Receptor 2 Signaling | Liliana Schaefer; |
| 13:05:00 | SIG 1: Lumican Mediated Neutrophil Migration | Seakwoo Lee, |
| 13:30:00 | SIG 1: Syndecan1 Shedding: An Innate Immune Response to Infection | Pyong Woo Park |
| 14:00:00 | SIG 2: Distinct Connections of FAK to Cell Survival and Directional Motility | David Schlaepfer, |
| 14:00:00 | SIG 1: Versican in Regulating Tumor Macrophages | Michael Karin |
| 14:00:00 | Clonal Expansion and Adhesive Signaling | Mark Ginsberg, |
| 14:00:00 | SIG 2: Integrin alpha-4 Activation Promotes Tumor Inflammation, Angiogenesis, and Lymphangiogenesis | Judith Varner, |
| 14:00:00 | SIG 2: Regulation of ECM Remodelling and Angiogenesis by Homeobox Genes | Nancy Boudreau, |
| 14:00:00 | "SIG 2: Integrins in Cancer" (Cunningham B) | |
| 14:30:00 | SIG 3: Role of gamma1-Laminins in Renal Collecting Ducts | Peter Yurchenco, |
| 14:30:00 | "SIG 3: Basement Membranes and the Kidney" (Cunningham C) | |
| 14:30:00 | SIG 3: Laminins and Kidney Function | Jeff Miner, |
| 14:30:00 | SIG 3: Collagen IV and the Kidney | Billy Hudson, |
| 14:30:00 | SIG 3: Asynchronous Laminin and Type IV Collagen Deposition in Developing Glomerular Basement Membranes | Dale Abrahamson, |
| 15:00:00 | Coffee Break | |
| 15:30:00 | Visualizing Human Tumor Cell Metastasis Using Transparent Zebrafish and High Resolution Intravital Microscopy | Konstantin Stoletov, |
| 15:30:00 | Introduction | Andries Zijlstra |
| 15:30:00 | Invadopodia and Mechanotransduction | Alissa M. , Weaver |
| 15:30:00 | "Special Interest Groups Session II" | |
| 15:30:00 | SIG 4: Matrix Remodeling in Cancer Invasion (Cunningham A) | |
| 15:30:00 | Anti-Podosome Therapy | SARA COURTNEIDGE |
| 15:30:00 | The Intersection of Planar Cell Polarity and ECM Remodeling During Collective Migration and Invasion | jason R Jessen |
| 16:00:00 | How Type III Collagen Influences Osteoblast Function through the Modulation of TGFbeta Signaling | Sherri Adams |
| 16:00:00 | Role of Thrombospondins in Regulating Osteoblast Progenitor Maintenance and Osteoblast Function | Andrea Alford, |
| 16:00:00 | Matrix Gla Proteins in Regulating Osteoblast Function | Raj Gopalakrishnan, |
| 16:00:00 | HtrA1: A Novel Matrix Modulator that Regulates Osteoblast Differentiation and Matrix Mineralization | Colette , Inkson |
| 16:00:00 | SIG 5: ECM Regulation of the Osteoblast-Lineage (Cunningham B) | |
| 16:00:00 | Post-Transcriptional Processing of Osteonectin in the Regulation of Osteoblast Differentiation | Anne M. Delany |
| 16:30:00 | PXE: A Multi-System Metabolic Disease Affecting the Elastic Structures | |
| 16:30:00 | Molecular Genetics of PXE | Jouni Uitto |
| 16:30:00 | Fibulin in Diseases | Mon-Li Chu |
| 16:30:00 | Elastin Aberrations in PXE | Olivier Le Saux |
| 16:30:00 | SIG 6: Heritable Diseases of Elastic Structures: The Paradigms of Pseudoxanthoma Elasticum (PXE) and Cutis Laxa (CL) | |
| 16:30:00 | CL: The Disease of Elastic Fibers | |
| 16:30:00 | Elastin Mutations in Cutis Laxa | Zsolt Urban |
| 16:30:00 | The Role of Patient Advocacy Organizations in Genetic Research | Sharon Terry |
| 18:30:00 | Welcome Reception (Randle Foyer) | |
| 19:30:00 | President’s Welcome and Founder’s Award Presentation to Paul Bornstein(Randle ABC) | Renato V. Iozzo |
| 19:45:00 | Keynote Lecture: MicroRNAs, the Immune System and Cancer(Randle ABC) | Carlo M Croce |
| 20:30:00 | End Of The Day | |
| Monday, December 8, 2008 | ||
| 07:30:00 | Breakfast (Randle Foyer) | |
| 07:30:00 | Exhibits(Randle Foyer) | |
| 07:30:00 | Registration (Randle Foyer) | |
| 08:30:00 | Extracellular Matrix Control of Stem Cell Niches | Marian F. Young |
| 09:05:00 | Glycomics of Proteoglycan Biosynthesis in ESC Differentiation | Robert J. Linhardt |
| 09:40:00 | Synthetic Biomimetic Matrices that Promote Osteoblastic Differentiation of Mesenchymal Stem Cells | SUSAN L. BELLIS |
| 10:00:00 | Coffee Break (Randle Foyer) | |
| 10:30:00 | Matrix Structure (Randle ABC) | |
| 10:30:00 | Senior Investigator Awardee: Extracellular Matrix and Vascular Development | Robert , Mecham |
| 10:30:00 | Plenary II | |
| 11:05:00 | Delayed Turnover of FGFR3: Pathogenetic Mechanism and Therapeutic Target in Achondroplasia | William . A Horton |
| 11:40:00 | Molecular based Structure and Ligation of the Collagen Fibril | Joseph , Orgel |
| 12:00:00 | Lunch Break (On Your Own) | |
| 13:30:00 | Induction of Physiologic and Pathologic Angiogenesis by TIMP-free proMMP-9 Derived Uniquely from Inflammatory Neutrophils | James Quigley |
| 13:30:00 | Concurrent C: ECM Turnover (America’s Cup ABCD) | |
| 13:30:00 | Concurrent B: Hypertriglyceridemia caused by mutation of the basement membrane proteoglycan Type XVIII collagen | Jeffrey D. Esko |
| 13:30:00 | Concurrent B: Proteoglycans (Cunningham ABC) | |
| 13:30:00 | Concurrent C: Biological Functions of Membrane-Type Matrix Metalloproteinases | Kenn Holmbeck |
| 13:30:00 | Concurrent Sessions | |
| 14:00:00 | Extra- and intracellular collagen degradation linked by uPARAP | Daniel Hargbøl Madsen |
| 14:00:00 | Fibulin-5 Inhibits Integrin- Induced ROS Production | Rolf Andrew Brekken |
| 14:00:00 | Concurrent A: Angiogenesis (Randle ABC) | |
| 14:00:00 | Concurrent B: Syndecan-1 Shedding Facilitates Airway Re-epithelialization. | |
| 14:20:00 | Concurrent B: Synstatin, a Sdc1 peptide, blocks αvβ3-dependent angiogenesis | DeannaLee Beauvais, |
| 14:20:00 | Concurrent C: Joint Degeneration in Mice Lacking Adequate Perlecan Levels | Kathryn D. Rodgers |
| 14:20:00 | Angiogenesis and Intravasation of PC-3 Dissemination Variants | Erin Conn, |
| 14:40:00 | Concurrent C: The role of caveolin-1 in pulmonary matrix remodeling | Olivier Le Saux |
| 14:40:00 | 2:40 PM Endorepellin evokes SHP1 activity in endothelial cells | Elizabeth. Nystrom |
| 14:40:00 | Concurrent B: Decorin binds to and downregulates the MET receptor | Silvia Goldoni, |
| 15:00:00 | Coffee Break (Randle and Cunningham Foyers) | |
| 15:30:00 | Concurrent Sessions | |
| 15:30:00 | Concurrent D: Retention of Thrombospondins in ECM, and views of TSP Evolution | Josephine C. Adams |
| 15:30:00 | Concurrent E: Control challenges in tissue growth and patterning | Arthur Lander |
| 15:30:00 | Concurrent F: Inflammation (America’s Cup ABCD) | |
| 15:30:00 | Concurrent D: Matricellular Proteins (Randle ABC) | |
| 15:30:00 | Concurrent F: Lung Inflammation: Old Concepts with Fresh Perspectives | Farrah Kheradmand |
| 15:30:00 | Concurrent E: Molecular & Computational Modeling (Cunningham ABC) | |
| 16:00:00 | Concurrent E: Modeling single and collective cell movements in 3D matrices | Muhammad Zaman |
| 16:00:00 | Concurrent D: COMP-specific Ribozyme: A New Strategy for Gene Therapy | Joseph Alcorn |
| 16:00:00 | Concurrent F: EGF-like domains of stabilin-2 recognizes PS during phagocytosis | Soyoun Kim, |
| 16:20:00 | Concurrent E: A Discrete Mathematical Model Simulates In Vitro Angiogenesis | Scott Sibole |
| 16:20:00 | FN-α4β1 Interactions Regulate MMP-9 Expression in Liver IR Injury | Sergio Duarte, |
| 16:20:00 | New Concurrent D: Regulation of fibronectin matrix assembly by tenascin-C | Wing To |
| 16:20:00 | Concurrent F: Intact hyaluronan promotes maintenance of immune tolerance. | Paul L. Bollyky |
| 16:40:00 | Concurrent D: DMP1 Isoforms Promote Differential Cell Attachment and Migration | Zofia von Marschall, |
| 16:40:00 | Concurrent E: The glycosaminoglycan-binding domain of CXC-chemokines controls neutrophil migration into the lungs | Charles W. Frevert |
| 17:00:00 | ASMB Business Meeting (Randle ABC) | |
| 17:00:00 | Poster Session I and Exhibitor Reception (4th Floor Foyers and Randle DE) | |
| 19:00:00 | End Of The Day | |
| 19:00:00 | Announcements | |
| 19:00:00 | Announcements for the next day | |
| Tuesday, December 9, 2008 | ||
| 07:25:00 | ||
| 07:25:00 | ||
| 07:30:00 | Registration (Randle Foyer) | |
| 07:30:00 | Breakfast (Randle Foyer) | |
| 07:30:00 | Exhibits (Randle Foyer) | |
| 08:30:00 | Junior Investigator Awardee: Fibulins: Implications in Vascular Development and Disease | Hiromi Yanagisawa |
| 08:30:00 | ECM Influences in Disease Pathogenesis (Randle ABC) | |
| 08:30:00 | Plenary III | |
| 08:50:00 | Location Matters: Matrix Regulation of Lung Inflammation and Remodeling | Paul W. Noble |
| 09:25:00 | The Bone Marrow Microenvironment in Neuroblastoma Progression | Yves A. DeClerck |
| 10:00:00 | Coffee Break (Randle Foyer) | |
| 10:30:00 | Genetic Analysis of Integrin Signaling in Mice | Reinhard Fässler |
| 10:30:00 | Plenary IV | |
| 10:30:00 | International Society for Matrix Biology (ISMB) Guest Symposium | |
| 11:00:00 | The proteoglycan metastatic signature of a cancer cell | Silvia Rossi, |
| 11:20:00 | A central role for decorin during vertebrate convergent extension | Jason J Zoeller |
| 11:40:00 | Prolyl 3-hydroxylase 1 null mice have abnormal bones and tendons | Janice Vranka, |
| 12:00:00 | Lunch Break (On Your Own) | |
| 13:30:00 | Concurrent G: Proteolytic Pathways (Randle ABC) | |
| 13:30:00 | Concurrent I: Heparanase Off/On Switch for Syndecan Core Protein-Mediated mTOR/NFAT Signaling | Gordon W. Laurie |
| 13:30:00 | Concurrent Sessions | |
| 13:30:00 | Concurrent G: TIMPs and Tissue Homeostasis | Rama Khokha |
| 13:30:00 | Concurrent H: Development (Cunningham ABC) | |
| 13:30:00 | Concurrent H: Signaling and Biomechanical Roles of Matrix During Early Xenopus Morphogenesis | RAY KELLER |
| 13:30:00 | Concurrent I: Glycosaminoglycans (America’s Cup ABCD) | |
| 14:00:00 | Concurrent G: MT1-MMP, vascular guidance tunnels, and EC-pericyte tube assembly | George Davis, |
| 14:00:00 | Concurrent I: Proteoglycan desulfation regulates endochondral ossification | Carmine Settembre, |
| 14:00:00 | Concurrent H: Scleraxis is required for normal heart valve formation in vivo | Joy Lincoln |
| 14:20:00 | Concurrent H: Skeletal abnormalities in quad- KO mice (TSP1, 3, 5, and Col 9) | Karen Posey, |
| 14:20:00 | Concurrent I: Heparan sulfate function in limb synovial joint formation | Maurizio , Pacifici |
| 14:20:00 | Concurrent G: Epilysin (MMP-28) functions in promoting epithelial cell survival | Anne Manicone, |
| 14:40:00 | Concurrent H: Dystroglycan is required for neural maintenance and guidance. | Robert G. Johnson |
| 14:40:00 | Concurrent G: TGFβ+EGF promotes PAI-1 sensitive collagen gel lysis and invasion. | Cynthia Wilkins, |
| 14:40:00 | Concurrent I: Role of heparan sulfate in limb skeletal development | Kazu Matsumoto, |
| 15:00:00 | Coffee Break (Randle and Cunningham Foyers) | |
| 15:30:00 | Concurrent J: Integrins (Randle ABC) | |
| 15:30:00 | Concurrent L: Molecular regulation of vascular calcification | Ann , Canfield |
| 15:30:00 | Concurrent L: Vascular Biology (America’s Cup ABCD) | |
| 15:30:00 | Concurrent J: Integrin-mediated activation of TGFβ | Dean Sheppard |
| 15:30:00 | Concurrent K: Basement Membrane (Cunningham ABC) | |
| 15:30:00 | Concurrent K: Basement Membrane Remodeling During Branching Morphogenesis: The Dynamic Interplay of Proteolysis and Proliferation | Matthew Hoffman, |
| 15:30:00 | Concurrent Sessions | |
| 16:00:00 | Concurrent J: Merlin Blocks Tumorigenesis by Inhibiting a Nuclear E3 Ligase | Filippo , Giancotti |
| 16:00:00 | Concurrent K: Mice deficient in the ECM protein WARP have nerve defects | Justin Allen, |
| 16:00:00 | Concurrent L: MAPKp38 determines Smad2/3 signaling in the fbn1 null mouse aorta | Luca Carta |
| 16:20:00 | Concurrent K: A Laminin-Nidogen Chimera Facilitates Basement Membrane Assembly | Stephanie Capizzi, |
| 16:20:00 | Pyk2 FERM regulates p53 in the absence of FAK | Nichol Miller, |
| 16:20:00 | Concurrent L: C-terminal Domain Modification in Mature Elastin | Thomas Broekelmann, |
| 16:40:00 | Concurrent L: Granzyme B and Perforin in atherosclerosis and skin pathologies | Wendy Boivin, |
| 16:40:00 | Mutant COL4A1 triggers oxidative stress in a genetic model of AMD | Yi-Chinn Weng, |
| 16:40:00 | Concurrent J: The alpha5beta1 integrin as mechanotransducer in chondrocytes | Linda Kock, |
| 17:00:00 | Poster Session II and Exhibitor Reception (4th Floor Foyers and Randle DE) | |
| 19:00:00 | Gala Reception (Randle ABC) | |
| 22:00:00 | End Of The Day | |
| 22:00:00 | Announcements | |
| Wednesday, December 10, 2008 | ||
| 07:30:00 | Registration (Randle Foyer) | |
| 07:30:00 | Breakfast (Randle Foyer) | |
| 07:30:00 | Exhibits (Randle Foyer) | |
| 08:30:00 | Plenary V Mechanical Influences (Randle ABC) | |
| 08:30:00 | Matrix Elasticity Directs Differentiation & De-Differentiation | Dennis Discher |
| 09:05:00 | Integration of Actin Dynamics and Adhesion in Cell Migration | Clare. Waterman-Storer |
| 09:40:00 | Matrix Cross Linking, Mechanotransduction and Tumor Progression | Valerie M Weaver |
| 10:00:00 | Coffee Break | |
| 10:30:00 | Concurrent N: Control of Gene Expression (Cunningham ABC) | |
| 10:30:00 | Concurrent Sessions | |
| 10:30:00 | Concurrent M: Invasion/Migration (Randle ABC) | |
| 10:30:00 | Concurrent O: ECM-Cytokines Interactions (America’s Cup ABCD) | |
| 10:30:00 | Concurrent O: LTBP1-Fibronectin Interactions in Regulation of Transforming Growth Factors | Sarah L. Dallas |
| 10:30:00 | Concurrent M: Biochemistry of Cell Migration Magic | ALEX , STRONGIN |
| 10:30:00 | Concurrent N: Pre and Postsynaptic Development in Zebrafish | Michael , Granato |
| 11:00:00 | Concurrent O: TGFβ1 Enhances Pancreatic Tumor Progression in SPARC-Null Mice | Shanna Arnold, |
| 11:00:00 | Concurrent M: GSK3b controls the intensity of tissue repair by regulating ET-1 | |
| 11:00:00 | Concurrent N: The response of articular chondrocyte microRNAs to stress | Gary Gibson, |
| 11:20:00 | Concurrent M: Cell polarity regulated by a FAKp120RasGAP- p190RhoGAP complex | Alok Tomar, |
| 11:20:00 | Concurrent O: Extracellular regulators of TGFβ signaling in bone. | Harikiran Nistala, |
| 11:20:00 | Concurrent N: Factors affecting splicing of scleroderma-associated LH2 mRNA | Seth Puneet, |
| 11:40:00 | Concurrent N: Postnatal Ablation of Sox9 in Mouse Cartilage | Stephen Henry, |
| 11:40:00 | Concurrent M: SPARC is required for collective cell migration during oogenesis | Nathalie Martinek, |
| 11:40:00 | Concurrent O: Collagen X is required for proper hematopoietic development | Elizabeth Sweeney, |
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