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Manufacturing antibodies

EUREKA project E! 3424 RECAN has developed a range of unique and highly specific monoclonal and polyclonal antibodies – the proteins produced in the blood which counteract bacteria, viruses or cancerous cells.

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Galapagos to build cystic fibrosis drug pipeline

Galapagos NV (Euronext: GLPG) announced the decision to pursue cystic fibrosis (CF) in its strategy to deliver breakthrough medicines to patients with orphan diseases.

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Acupuncture can Transmit Serious Diseases Like HIV, Hepatitis

Acupuncture treatment may lead to transmission of bacterial infections, hepatitis B and C, and even HIV, health experts have warned. Microbiologists at the University of Hong Kong insist that use of contaminated needles can have devastating results, reports The China Daily.

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Windpipe transplant success in UK child

A 10-year-old British boy has become the first child to undergo a windpipe transplant with an organ crafted from his own stem cells.

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Perception of effort, not muscle fatigue, limits endurance performance

The physiological theory that underpins all endurance training and coaching for the last 100 years has just been disproved.

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A molecular brake for the bacterial flagellar nanomotor

Biozentrum researchers have now discovered that Escherichia coli bacteria harness a sophisticated chemosensory and signal transduction machinery that allows them to accurately control motor rotation, thereby adjusting their swimming velocity in response to changing environments.

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Study finds H1N1 flu in pregnancy is critical risk

Pregnant women in Australia and New Zealand who had pandemic H1N1 flu were 13 times more likely to become critically ill and be admitted to hospital, researchers said on Friday, reports Reuters.

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GlaxoSmithKline commences Relovair Phase III asthma programme

axoSmithKline (GSK) announced today that the first asthma patient has commenced treatment with Relovair™ in an asthma exacerbation study, marking the start of the Phase III clinical development programme with this once daily therapy,

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Deuterium Depletion: a new concept in anticancer drug development

The 1st International Symposium on Deuterium Depletion will be held on 13–14 May 2010 in Budapest, Hungary, and will enable researchers and medical practitioners to get acquainted with deuterium depletion, a novel tool of submolecular medicine.

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Anti-Cancer Agents, Herceptin® and Xeloda® Filed for HER2-positive Advanced or Recurrent Gastric Cancer

Chugai Pharmaceutical Co., Ltd. announced today that it filed an application with the Japanese Ministry of Health, Labour and Welfare, seeking additional approval of combination therapy with trastuzumab (genetical recombination),

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How Cells Protect Themselves from Cancer

Cells have two different protection programs to safeguard them from getting out of control under stress and from dividing without stopping and developing cancer. Until now, researchers assumed that these protective systems were prompted separately from each other.

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Babies born with severe cleft palates: Promising breakthrough without complex surgery

Scientists working on a treatment for babies born with cleft palates have made a promising breakthrough and the first clinical trials are planned for early next year. Clefts are the most common birth defect in Britain, with one in every 700 babies affected

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Molecular basis for Pseudomonas aeruginosa chronic cystic fibrosis infections

Biozentrum researchers identified Small Colony Variants of Pseudomonas aeruginosa to be a hallmark of chronic infection in cystic fibrosis patients. Theses findings suggest that SCV-mediated persistence might be a good target for antimicrobial chemotherapy.

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Hypnotherapy 'can help' irritable bowel syndrome

Greater use of hypnotherapy to ease the symptoms of irritable bowel syndrome would help sufferers and might save money, says a gastroenterologist.

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The proteins that help plants keep time

Researchers at the RIKEN Plant Science Center have clarified the function of three proteins that play a central role in the circadian clock in plants. The finding, to appear in the journal The Plant Cell, opens the door to the engineering of plant clock systems, with powerful applications to agriculture.

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What makes us unique? Not only our genes

Once the human genome was sequenced in 2001, the hunt was on for the genes that make each of us unique. But scientists have found that we differ from each other mainly because of differences not in our genes, but in how they’re regulated – turned on or off, for instance.

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New technique reduces tobacco smoke damage to lungs in mice

Researchers in Australia have demonstrated that blocking a certain protein can reduce or prevent cigarette smoke-induced lung inflammation in mice. Inflammation underlies the disease process of chronic obstructive pulmonary disease (COPD) and many other smoking-related ailments.

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Hypnotherapy eases irritable bowel syndrome symptoms

Hypnotherapy seems to be very effective for easing the distressing symptoms of irritable bowel syndrome (IBS), and in a goodly proportion of cases, clears up symptoms altogether, reveal experts during a wide ranging discussion of the condition in a Frontline Gastroenterology podcast.

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Early baldness and lower risk of prostate cancer link 'not conclusive'

Men who start losing their hair at an early age may be less likely to develop prostate cancer in the future, new research suggests.But Cancer Research UK said that the results contradict those of previous studies and that further research is needed to provide more reliable evidence.

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Novartis receives approval in the European Union for Menveo®, first quadrivalent conjugate vaccine in the EU to help prevent meningococcal disease

Meningococcal disease is a major cause of bacterial meningitis and sepsis with high consequent disability and mortality rates worldwide[1]

Dominant groups of meningococcal disease vary by country and region, and can change over time, making it an even more unpredictable disease[2]

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