9th Annual Biomarkers Congress

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Peer Reviewed Papers, Books, Chapters

Year Title Citation Authors
1. 2009 Caveolin-1−∕− Mammary Stromal Fibroblasts Share Characteristics with Human Breast Cancer-Associated Fibroblasts Am J. Pathol. 2009 Mar; 174(3): 746-61.
2. 2009 Cancer stem cells and the cell cycle: targeting the drive behind breast cancer. Expert Rev. Anticancer Ther. 2009 Mar., 9(3), 275-279.
3. 2009 MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma Mol Cancer Ther.2009; Mar 8(3): 543-51. Epub 2009 Mar 3.
4. 2009 Dissociation of EphB2 Signaling Pathways Mediating Progenitor Cell Proliferation and Tumor suppression Cell. (2009)
5. 2009 Altered Expression of DACH1 and Cyclin D1 in Endometrial Cancer Cancer Biol Ther. 2009 Aug 8; 8(16).
6. 2009 An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease spread and epithelial Akt activation Cell Cycle August 2009; 8 (15):1-5
7. 2009 An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers Am. J. Pathol. 2009 Jun; 174(6):2023-34. Epub 2009 May 1.
8. 2009 Clinical and Translational Implications for the Caveolin Gene Family: Lessons from Mouse Models and Human Genetic Disorders Lab Invest. 2009 Jun; 89(6):614-23. Epub 2009 Mar 30.
9. 2009 Towards a new “stromal-based” classification system for human breast cancer prognosis and therapy Cell Cycle 8:11, 1654-58; 1 June 2009.
10. 2009 The Cell Fate Determination Factor DACH1 is expressed in Estrogen Receptor α (ERα) positive breast cancer and represses ERα signaling Cancer Research (2009)
11. 2009 The Dachshund gene in Development and Hormone-Responsive Tumorigenesis. Trends in Endo & Met (2009
12. 2009 Loss of Caveolin-3 Induces a Lactogenic Microenvironment that Is Protective Against Mammary Tumor Formation Am J. Pathol. 2009 Feb; 174 (2):613-629.
13. 2008 DACH1 negatively regulates the human RANK ligand gene expression in stromal/preosteoblast cells J Cell Biochem. 2008 Apr 15; 103 (6): 1747-59.
14. 2008 Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase Mol. Biol. Cell. 2008 Apr; 19(4):1378-1390 Epub 2008 Jan 23.
15. 2008 Nerve growth factor regulation of cyclin D1 in PC12 cells through a p21RAS ERK-Pathway requires cooperative interactions between Sp1 and NF-kb Mol Biol Cell. 2008 Jun; 19(6):2566-78. Epub 2008 Mar 26
16. 2008 Alternate cyclin D1 mRNA splicing modulates p27kIP1 binding and cell migration J Biol Chem. 2008 Mar 14; 283 (11): 7007-15 Epub 2008 Jan
17. 2008 Regulation of host cell cyclin D1 by Trypanosoma cruzi in myoblasts Cell Cycle 2008 Feb 15; 7(4): 500-503. Epub 2007 Nov 18
18. 2008 Endothelial Progenitor Cells Significantly Contribute to Vasculatures in Human and Mouse Breast Tumors The Open Hematology Journal, (2008) 1: 30-62
19. 2008 ErbB2 induces Notch activity and function in breast cancer cells Clinical and Translational Science, (2008) 1(2): 107-115.
20. 2008 Acetylation in Nuclear Receptor Signaling and the Role of Sirtuins Mol Endocrinol. 2008 Mar.; 22(3): 539-545, Epub 2007 Dec. 28
21. 2008 Inhibition of Cyclin D1 Gene Transcription by BRG-1 Cell Cycle 2008 Mar 1; 7(5): 647-55. Epub 2007 Dec 12
22. 2008 Human Breast Cancer-Associated Fibroblasts (CAFs) Show Caveolin-1 downregulation and RB Tumor Suppressor Functional Inactivation: Implications for the Response to Hormonal Therapy Cancer Biol. Ther. 2008 Aug; 7(8):1212-25 Epub 2008 Aug 30.
23. 2008 Hearts lacking caveolin-1 develop hypertrophy with normal cardiac substrate metabolism. Cell Cycle. 2008 Aug 15;7(16):2509-18 Epub 2008 Aug 26.
24. 2007 High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A J Biol Chem. 2007 Oct 19; 282 (42): 31038-45. Epub 2007 Aug 1.
25. 2007 Mechanical force modulates global gene expression and β-catenin signaling in colon cancer cells J Cell Sci. 2007 Aug 1; 120(15): 2672-82. Epub 2007 Jul 17
26. 2007 ErbB-2 induces cyclin D1 gene activity in prostate epithelial cells in vitro and in vivo: Requirement of cyclin D1 for ErbB-2 induced prostate cell proliferation Cancer Res. 2007 May 1; 67(9): 4364-72.
27. 2007 The functional significance of nuclear receptor acetylation Steroids 2007 Feb; 72 (2):221-230. Epub 2007 Feb. 7.
28. 2007 Akt1 governs breast cancer progression in vivo. Proc. Natl. Acad. Sci. USA, 2007 May 1; 104(18): 7438-43. Epub 2007 May 17.
29. 2007 Breast cancer cell proliferation is inhibited by BAD: Regulation of cyclin D1. J Biol Chem. 2007 Sep 28; 282 (39): 28864-73. Epub 2007 Aug 1.
30. 2007 Nuclear Hormone Receptor Acetylation and Transcriptional Regulation Trends Endocrinol. Metab. 2007 Nov 18(9): 356-64 Epub 2007 Oct 26
31. 2007 Stabilization of SMAR1 mRNA by PGA2 involves a stem loop structure in the 5’UTR Nucleic Acids Res. 2007; 35 (18): 6004-16. Epub 2007 Aug 28.
32. 2007 Caveolin-1 is required for the upregulation of Fatty Acid Synthase (FASN), a Tumor Promoter, During Prostate Cancer Progression Cancer Biol Ther. 2007 Aug; 6(8)1263-8 Epub May 17.
33. 2006 Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1 regulated transcription factor ZONAB/DbpA. Mol. Cell Biol, 2006 Mar; 26(6) 2387-98
34. 2006 Light-Activated Gene Therapy, New Selective Therapies for Disease Journal of Nuclear Medicine, Vol. 47, No. 12 December 2006 p. 21-22N
35. 2006 Regulation of progesterone receptor signaling by BRCA1 in mammary cancer. Perspectives, Nuclear Receptor Signaling, Vol. 4, p. 1-4, 2006.
36. 2006 Epigenetics and the estrogen receptor. Estrogens and Human Diseases Ed: H. Leon Bradlow, Giuseppe Carruba Ann N Y Acad Sci. 2006 Nov.; 1089: 73-87.
37. 2006 Caveolin-1, mammary stem cells, and estrogen-dependent breast cancer. Cancer Res. 2006 Nov. 15; 66(22) 10647-1051.
38. 2006 SIRT1 and Endocrine Signaling Trends Endocrinol Metab. 17:186-191, 2006.
39. 2006 Remembering team science is for the patients Cancer Biol Ther. 2006, 5:4 449-452.
40. 2006 Regulation of progesterone receptor signaling by BRCA1 in mammary cancer. Nucl Recept Signal. 2006; 4:e006: Epub 2006 Apr. 28.
41. 2006 The Biology Behind. Commentary on Yamamoto, et al. Antisense to cyclin D1 inhibits VEGF-Stimulated growth of vascular endothelial cells. Implication of tumor vascularization Clin Cancer Res. (2006), 12(15):4459-62
42. 2006 Epigenetic regulation of nuclear steroid receptors. Biochem Pharmacol. 2006 Nov. 30; 72(11) 1589-1596, Epub 2006 Jul. 17.
43. 2006 Cyclin D1 Functions in Cell Migration. Cell Cycle. 2006 Nov. 1; 5(21): 2440-2. Epub 2006 Sep. 22
44. 2006 3-Phosphoinositide-dependent Protein Kinase-1 Activates the Peroxisome Proliferator-Activated Receptor-g and Promotes Adipocyte Differentiation Mol. Endocrinol.2006 Feb; 20(2): 268-78. Epub 2005 Sep 8.
45. 2006 Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness. Am. J. Pathol. 2006 Jan; 168(1):292-309.
46. 2006 Trypanosoma Cruzi Infection Induces Proliferation of Vascular Smooth Muscle Cells Infect. Immun. 2006 Jan; 74: 152-159
47. 2006 Conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness. Am. J. Pathol. 2006 Jan; 168(1): 292-309.
48. 2005 The NF2 tumor suppressor gene product, Merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression Mol. Cell Biol. 2005 Mar; 25(6): 2384-94.
49. 2005 CDK inhibitors as anticancer agents Enzyme Inhibitors Ed: Eddy Yue and Paul J. Smith, CRC Press, Vol. 2, Chapter 27, 2005
50. 2005 Estrogen receptor acetylation and phosphorylation in hormone responses. Breast Cancer Online. Vol. 8, Issue 09, Sept. 2005 e46
51. 2005 Activation of cyclin D1 by estradiol and spermine in MCF-7 breast cancer cells: A mechanism involving the p38 kinase and phosphorylation of ATF-2. Oncol. Res. 2005; 15(3): 113-28.
52. 2005 A β-Catenin signaling and regulation of cyclin D1 Promoter in NRK-49F Cells Transformed by Down-regulation of the Tumor Suppressor Lysyl Oxidase Biochim Biophys Acta. (2005) 207:16934-41.
53. 2005 Positherapy: targeted nuclear therapy of breast cancer with 18F-2-deoxy-2-fluoro-D-glucose (18F-FDG). Cancer Res. 2005 Feb 1; 65 (3): 698-702
54. 2005 Differential Effects of 16 a-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving transcription factor ATF-2 in MCF-7 breast cancer cells. J Mol Endocrinol. 2005 Feb; 34(1): 91-105.
55. 2005 Caveolin-1-Deficient Mice Have An Increased Mammary Stem Cell Population, with Upregulation of Wnt/b-Catenin Signaling. Cell Cycle. 2005 Dec; 4(21) 1808-16. Epub 2005 Dec 22
56. 2005 Bombesin Regulates Cyclin D1 Expression Through the Early Growth Response Protein EGR-1 in Prostate Cancer Cells. Cancer Res. (Nov 2005) 65(21): 9934-42
57. 2005 Cyclin D1 Represses p300 Transactivation Through a CDK-Independent Mechanism J. Biol. Chem. 2005 Aug 19; 280(33): 29728-42.Epub 2005 Jul 10.
58. 2005 Cyclin D1 Antagonizes BRCA1 Repression of Estrogen Receptor a Activity. Cancer Res 2005 Aug 1; 65(15):6557-67.
59. 2005 A study of cytotoxic synergy of UCN-01 and flavopiridol in syngeneic pair of cell lines. Invest. New Drugs. 2005 Aug; 23(4):299-309.
60. 2005 Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NF-kB activation and cyclin D1 up-regulation Toxicol Appl Pharmacol. 2005 Jun 1; 205 (2): 133-48.
61. 2005 Adipocyte-Derived Collagen VI Affects Early Mammary Tumor Progression in vivo, Demonstrating a critical Interaction in the Tumor/Stroma Microenvironment. J. Clin. Invest. 2005 May; 115 (5): 1163-76. Epub 2005 Apr 14
62. 2005 Cyclin D1 inhibits PPARg-mediated adipogenesis through HDAC recruitment J. Biol. Chem. 2005 April 29; 280 (17) 16934-41. Epub 2005 Feb 14.
63. 2005 Gastrin Stabilises b-Catenin Protein in Mouse Colorectal Cancer Cells Br J. Cancer 2005 April 25; 92 (8): 1581-7.
64. 2005 Mayven induces c-Jun expression and cyclin D1 activation in breast cancer cells. Oncogene, 2005 Mar 31; 24(14): 2398-409.
65. 2005 Caveolin-1 Promotes Tumor Progression in an Autochthonous Mouse Model of Prostate Cancer: Genetic Ablation of Cav-1 Delays Advanced Prostate tumor development in TRAMP mice J. Biol. Chem. 2005 Jul 1; 280 (26):25134-45. Epub 2005 Mar 30.
66. 2005 SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell-cycle regulatory domain 1 J. Biol. Chem., 2005 Mar 18; 280 (11): 10264-76. Epub 2005 Jan 4.
67. 2005 Role of NF-kB signaling in hepatocyte growth factors/scatter factor-mediated cell protection. Oncogene 2005 Mar 3; 24(10): 1749-66.
68. 2004 Combined Loss of INK4a and Caveolin-1 Synergistically Enhances Cell Proliferation and Oncogene-Induced Tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia, J. Biol. Chem. 2004 Jun 4; 279(23): 24745 –56. Epub 2004 Mar 25.
69. 2004 Phosphorylation of estrogen receptor a blocks its acetylation and regulates estrogen sensitivity Cancer Res. 2004 Dec 15; 64(24): 9199-208
70. 2004 Caveolin-1 Gene Disruption Promotes Mammary Tumorigenesis and Dramatically Enhances Lung Metastasis In Vivo: Role of Cav-1 in Cell Invasiveness and Matrix Metalloproteinase (MMP-2/9) Secretion J. Biol. Chem. 2004 Dec 3; 279: (49): 51630-46. Epub 2004 Sep 7.
71. 2004 Trypanosoma cruzi Infection Activates Extracellular Signal-Regulated Kinase in Cultured Endothelial and Smooth Muscle Cells Infect Immun 2004 Sep; 72(9): 5274-82
72. 2004 Bone Morphogenetic Protein signaling regulates postnatal hair follicle differentiation cycling Am. J. Pathology 2004 Sep; 165 (3): 729-740.
73. 2004 Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice Mol Cell Biol. 2004 Sep; 24(17):7598-611.
74. 2004 The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity J Biol Chem. 2004 Jul 9; 279 (28): 29436-49. Epub 2004 Apr 30
75. 2004 The Inhibitor of cylcin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements Cancer Res. 2004 Jun 15; 64(12):4122-30.
76. 2004 Gastrin-Mediated Activation of cyclin D1 Transcription Involves β-Catenin and CREB pathways in Gastric Cancer Cells Oncogene. 2004 Apr 29; 23(20):3689-99.
77. 2004 PPARg activation modulates cyclin D1 transcription via b-Catenin-independent and cAMP-response element-binding protein-dependent pathways in mouse hepatocytes. J. Biol. Chem. 2004 Apr 23; 279(17):16927-38. Epub 2004 Feb 5.
78. 2004 Intestinal tumor progression is associated with altered function of KLF5. J. Biol. Chem. 2004 Mar 26; 279(13):12093-101. Epub 2004 Jan 15.
79. 2003 Loss of Caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic Mice. Mol. Biol. Cell. 2003 Mar; 14:1027-42
80. 2003 Cyclin D1 governs adhesion and motility of Macrophages. Mol. Biol. Cell. 2003 May; 14: 2005-15. Epub 2003 Feb 21.
81. 2003 IKKa regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf. Mol. Biol. Cell 2003 Feb; 14:585-599.
82. 2003 Role of BRCA1 in Heat Shock Response Oncogene. 2003 Jan 9; 22(1):10-27.
83. 2003 Cyclin D1 repression of Peroxisome Proliferator-activated Receptor g (PPARg) expression and transactivation. Mol. Cell. Biol. 2003 23(17):6159-73
84. 2003 15d-PGJ(2) inhibits oxidized LDL-induced macrophage proliferation by inhibition of GM-CSF production via inactivation of NF-kB Biochem Biophys Res Commun. 2004 Feb 13; 314(3): 817-23.
85. 2003 p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells J Biol Chem. 2004 Jan 9; 279(2):1422-8. Epub 2003 Oct 6.
86. 2003 DACH1 inhibits TGF-b signaling through binding Smad4. J. Biol. Chem. 2003 Dec 19; 278(51):51673-84. Epub 2003 Oct 2
87. 2003 Acetylation of Androgen Receptor enhances coactivator binding and promotes prostate cancer cell growth Mol. Cell Biol. 2003 Dec; 23:8563-75
88. 2003 BRCA1 Inhibition of Telomerase Activity in Cultured Cells. Mol. Cell. Biol. 2003 Dec; 23(23):8668-90
89. 2003 Trans-repression of β-Catenin activity by nuclear receptors J. Biol. Chem. 2003 Nov 28; 278(48):48137-45. Epub 2003 Sep 12.
90. 2003 Activation of transcription factors AP-1 and NF-kB in murine Chagasic myocarditis. Infect. Immun. 2003 May; 71(5):2859-67.
91. 2003 Amino acids regulate hepatocyte proliferation through modulation of cyclin D1 expression. J. Biol. Chem. 2003 Jul 11; 278:25853-858. Epub 2003 May 7.
92. 2003 Dual Mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells. J. Natl. Cancer Inst. 2003 May 21; 95(10):733-40.
93. 2003 Gene Expression Phenotypic Models that predict the activity of oncogenic pathways. Nat. Genet. 2003 Jun; 34(2)226 - 30
94. 2003 AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter Cancer Res. 2003 Oct 15; 63(20):6802-8.
95. 2003 Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization Oncogene 2003 Sep 25; 22(41):6408-23
96. 2003 Dissecting the Roles of b-Catenin and Cyclin D1 During Mammary Development and Neoplasia Proc. Natl Acad Sci USA. 2003 Sep 30; 100(20):11400-405. Epub 2003 Sep 17.
97. 2003 Gastrin-Induced Gastric Adenocarcinoma growth is mediated through Cyclin D1 Am. J. Physiol. Gastrointest. Liver Physiol. 2003 Jul; 285(1):G217-22. Epub 2003 Feb 26.
98. 2003 The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis. Cancer Res. 2003 Jun 15; 63(12):3395-402.
99. 2003 Nuclear Receptor Modifications and Endocrine Cell Proliferation. J. Steroid Biochem. Mol. Biol. 2003 Jun; 85(2-5):133-138
100. 2002 Opposing action of estrogen receptors a and b on cyclin D1 gene expression. J Biol Chem. 2002 Jul 5; 277(27): 24353-60. Epub 2002 May 1
101. 2002 Spatially discrete, light-driven protein expression. Chem Biol. 2002 Dec; 9(12):1347-53
102. 2002 Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1. J. Biol. Chem. 2002 277(19):16464-9
103. 2002 Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells J. Biol. Chem. 2002 Nov 29; 277: 45847-53. Epub 2002 Sep 15.
104. 2002 Galectin-3 enhances cyclin D(1) promoter activity through SP1 and a cAMP-responsive element in human breast epithelial cells Oncogene. 2002 Nov 14; 21(52):8001-10.
105. 2002 Effect of N-proopiomelanocortin (1-77) and (1-49) infusions on adrenal expression of cyclin D1 in the fetal sheep Endocr Res. 2002 Nov; 28(4):625-9
106. 2002 Caveolin-1-deficient Mice Show Accelerated Mammary Gland Development During Pregnancy, Premature Lactation, and Hyperactivation of the Jak-2/STAT5a Signaling Cascade Mol. Biol. Cell. 2002 Oct; 13(10): 3416-30
107. 2002 Caveolin-1 Mutations (P132L and Null) and the Pathogenesis of Breast Cancer: Caveolin-1 (P132L) Behaves in a Dominant-Negative Manner and Caveolin-1 (-/-) Null Mice Show Mammary Epithelial Cell Hyperplasia. Am. J. Pathol. 2002 Oct; 161(4): 1357-69
108. 2002 Flavopiridol and trastuzumab synergistically inhibit proliferation of breast cancer cells: association with selective cooperative inhibition of cyclin D1-dependent kinase and Akt signaling pathways Mol. Cancer Ther. 2002 Jul; 1(9): 695-706.
109. 2002 Role of cardiac myocyte-derived endothelin-1 in chagasic cardiomyopathy: molecular genetic evidence. Clin Sci (Lond). 2002 Aug; 103 Suppl 48:263S-266S
110. 2002 Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5. Mol. Cell Biol. 2002 Aug; 22(16):5975-88.
111. 2002 Regulation of airway smooth muscle cyclin D1 transcription by Protein kinase C-d. Am J. Respir. Cell Mol. Biol. 2002 Aug; 27(2):204-213.
112. 2002 Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1 Cancer Res. 2002 Jul 15; 62(14):3997-4006.
113. 2002 In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb. Dev. Biol. 2002 Sep 1; 249(1):108-20.
114. 2002 Interferon-b activates multiple signaling cascades in primary human microglia. J Neurochem. 2002 Jun; 81(6):1361-71.
115. 2002 The RASSF1A tumor suppressor blocks cell cycle progression and inhibits Cyclin D1 accumulation Mol. Cell Biol. 2002 Jun; 22(12):4309-18.
116. 2002 E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kB activity that facilitates MnSOD-mediated ROS elimination Mol. Cell. 2002 May; 9(5):1017-29.
117. 2002 Androgen receptor acetylation governs Trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function. Mol. Cell Biol. 2002 May; 22(10):3373-88.
118. 2002 Differential effects of p21WAF1/CIP1 deficiency on MMTV-ras and MMTV-Myc mammary tumor properties Cancer Res. 2002 Apr 1:62(7): 2077-84
119. 2002 p300 modulates the BRCA1 inhibition of estrogen receptor activity Cancer Res. 2002 Jan 1; 62(1):141-51
120. 2002 Indomethacin induces differential expression of β-Catenin, g-Catenin and T-cell factor target genes in human colorectal cancer cells Carcinogenesis 2002 Jan; 23(1):107-14.
121. 2002 Rhenium-188 as an alternative to Iodine-131 for treatment of breast tumors expressing the sodium/iodide symporter (NIS) Nucl. Med. Biol. 2002 Jan; 29(1):13-8
122. 2001 TGFb and PTHrP control chondrocyte proliferation by activating cyclin D1 expression Mol. Biol. Cell 2001 Dec; 12:3852-63.
123. 2001 Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways. Mol. Med. 2001 Dec; 7(12):816-830.
124. 2001 Transcriptional activation of Cyclin D1 promoter by fak contributes to cell cycle progression. Mol. Biol. Cell. 2001 Dec; 12(12):4066-77
125. 2001 Prolactin negatively regulates caveolin-1 gene expression in the mammary gland during lactation, via a Ras-dependent mechanism. J. Biol. Chem. 2001 Dec 21; 276(51): 48389-97. Epub 2001 Oct 15.
126. 2001 Caveolin-1 null mice are viable, but show evidence of hyperproliferative and vascular abnormalities J. Biol. Chem. 2001 Oct 12; 276(41):38121-38. Epub 2001 Jul 16.
127. 2001 Protein Kinase C isoforms involved in the transcriptional activation of cyclin D1 by transforming Ha-Ras J. Biol. Chem. 2001 Nov 16; 276(46): 42834-42. Epub 2001 Sep 10.
128. 2001 Negative regulation of the Wnt-b-Catenin pathway by the transcriptional repressor HBP1 EMBO. J. 2001 Aug 15; 20(16), 4500-11
129. 2001 A novel cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells Cancer Res. 2001 Aug 15; 61(16):6170-7.
130. 2001 Disruption of BRCA1 LXCXE alters BRCA1 functional activity and regulation of RB family but not RB protein binding Oncogene 2001 Aug 9; 20(35):4827-41.
131. 2001 Caveolin-1 expression negatively regulates cell cycle progression by inducing G (0)/G (1) arrest via a p53/p21 (WAF1/Cip1)-dependent mechanism Mol. Biol. Cell 2001 Aug; 12(18):2229-44.
132. 2001 Activating transcription factor 3 induces DNA synthesis and expression of cyclin D1 in Hepatocytes J. Biol. Chem. 2001 Jul 20; 276(29):27272-80. Epub 2001 May 24.
133. 2001 Direct Acetylation of the Estrogen Receptor a Hinge Region by p300 Regulates Transactivation and Hormone Sensitivity J. Biol. Chem. 2001 May 25; 276(21):18375-83. Epub 2001 Mar 9.
134. 2001 Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner Mol. Endocrinol. 2001 May; 15(5)797-811
135. 2001 Evidence that Myc isoforms transcriptionally repress caveolin-1 gene expression via an INR-dependent mechanism. Biochemistry. 2001 Mar 20; 40(11):3354-62
136. 2001 Presenilin 1 regulates b-Catenin/T cell factor/lymphoid enhance factor-1 signaling independently of b-Amyloid precursor protein and Notch processing J.Cell Biol. 2001 Feb 19; 152(4):785-94
137. 2001 Role of direct interaction in BRCA1 inhibition of estrogen receptor activity Oncogene 2001 Jan 4; 20(1):77-87
138. 2001 Bcl-2 induces cyclin D1 promoter activity in human breast epithelial cells independent of cell anchorage Cell Death Differ. 2001 Jan; 8:44-50.
139. 2001 Ligand-independent activation of oestrogen receptora by caveolin-1. Biochem. J. 2001 Oct 1; 359(Pt 1):203-10
140. 2001 Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr (14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress. J. Biol. Chem. 2001 Mar 16; 276(11):8094-103. Epub 2000 Nov 27.
141. 2000 The mammary gland iodide transporter is expressed during lactation and in breast cancer Nat. Med. 2000 Aug; 6(8):871-8
142. 2000 Caveolin-1 expression inhibits Wnt/b-catenin/Lef-1 signaling by recruiting b-Catenin to caveolae membrane domains J. Biol. Chem. 2000 Jul 28; 275(30):23368-77
143. 2000 The cyclin D1 gene is transcriptionally repressed by caveolin-1. J. Biol. Chem. 2000 Jul 14; 275(28):21203-09
144. 2000 Caveolin-1 inhibits EGF-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1. J. Biol. Chem. 2000 Jul 7; 275(27):20717-25.
145. 2000 p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation J. Biol. Chem. 2000 Jul 7; 275(27):20853-60
146. 2000 The application of a lentiviral vector for gene transfer in fetal human hepatocytes. J. Gene Med. 2000 May-Jun; 2(3): 186-93.
147. 2000 Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein Mol. Cell Biol. Res. Commun. 2000 Jun;3(6):352-9
148. 2000 Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway Mol. Cell. Biol. 2000 Jan; 20(2):672-83
149. 2000 Immunohistochemical Examination of the INK4 and CIP inhibitors in the rat neonatal cerebellum: cellular localization and the impact of protein calorie malnutrition Brain Res. 2000 Feb 7; 855(1):11-22
150. 2000 b-Catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression Proc. Natl. Acad. Sci. USA 2000 Apr 11; 97(8):4262-6
151. 2000 Sustained mammary gland-directed, ponasterone A-inducible expression in transgenic mice FASEB J. 2000 May; 14(7):877-84
152. 2000 Ras inactivation of the Rb pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1epithelial cells J. Biol. Chem. 2000 Dec 29; 275(52):40916-24.
153. 2000 Caveolin-1 expression is down-regulated in cells transformed by the HPV in a p53 dependent manner. Replacement of Caveolin-1 expression suppresses HPV-mediated cell transformation Biochemistry 2000 Nov 14; 39(45):13916-24
154. 2000 Trypanosoma cruzi Infection (Chagas’ Disease) of mice causes activation of the mitogen-activated protein kinase cascade and expression of endothelin-1 in the myocardium. J. Cardiovasc. Pharmacol. 2000 Nov 36(5 Suppl 1):S148-50.
155. 2000 Distribution of the EGF receptor in Chemotaxing Adenocarcinoma Cells Mol. Biol. Cell (2000) 11(11):3873-3883.
156. 2000 Ral GTPases contribute to regulation of cyclin D1 through activation of NF -kB Mol. Cell Biol. 2000 Nov; 20(21):8084-92.
157. 2000 Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb-7 signaling cassette Mol. Endocrinol. 2000 Nov; 14(11):1750-75.
158. 2000 The Application of high density microarray for analysis of mitogenic signaling and cell-cycle in the adrenal. Endocr. Res. 2000 Nov; 26(4):807-23
159. 2000 The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3b and cAMP-responsive element-binding protein-dependent pathways J. Biol. Chem. 2000 Oct 20; 275(42):32649-57.
160. 2000 Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation. Am. J. Physiol. Gastrointest Liver Physiol. 2000 Oct; 279(4):G806-14
161. 2000 Myocardial expression of endothelin-1 in murine Trypanosoma cruzi infection. Cardiovasc. Pathol. 2000 Sep-Oct; 9(5):257-65
162. 2000 Regulation of cyclin D1 expression and DNA synthesis by phoshatatidylinositol 3-kinase in airway smooth muscle cells Am. J. Respir. Cell Mol. Biol. 2000 Oct; 23(4):436-43
163. 2000 Transgenic overexpression of caveolin-3 in skeletal muscle fibers induces a Duchenne-like muscular dystrophy phenotype. Proc. Natl Acad Sci. USA. 2000 Aug 15; 97(17):9689-94
164. 2000 Transforming growth factor-b1 recruits histone deacetylase 1 to a p130 repressor complex in transgenic mice in vivo Cancer Res. 2000 Aug 15; 60(16):4531-7
165. 2000 Gut-enriched Krüppel-like factor represses cyclin D1 promoter activity through Sp1 motif Nucleic Acids Res. 2000 Aug 1; 28(15):2969-76.
166. 1999 AP-2 mediates transcriptional activation of the CYP11A1 gene by interaction with Sp1 rather than binding to DNA Mol. Endocrinol. 1999 Aug; 13(8):1402-16.
167. 1999 Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis J. Biol. Chem. 1999 Nov 26; 274(48):34186-95
168. 1999 Caveolin-1 potentiates estrogen receptor a (ERa) signaling. Caveolin-1 drives ligand-independent nuclear translocation and activation of ERa. J. Biol. Chem. 1999 Nov 19; 274(47):33551-56
169. 1999 p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity J. Biol. Chem. 1999 Nov 5; 274(45): 32333-41.
170. 1999 Down-regulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol Cancer Res. 1999 Sep 15; 59(18) 4634-41.
171. 1999 Integration of Rac-dependent regulation of cyclin D1 transcription through an NF-kB-dependent pathway J. Biol. Chem. 1999 Sep 3; 274(36):25245-49.
172. 1999 Stat3 as an Oncogene Cell 1999 Aug 6; 98(3):295-303
173. 1999 NF-kB controls cell growth and differentiation through transcriptional regulation of cyclin D1 Mol. Cell Biol. 1999 Aug; 19(8):5785-99.
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