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Peer Reviewed Papers, Books, Chapters

Year Title Citation Authors
1. 2008 Hepatic repopulation with stably transduced conditionally immortalized hepatocytes in the Gunn rat J Hepatol;49:99-106
2. 2008 Correction of hyperoxaluria by liver repopulation with hepatocytes in a mouse model of primary hyperoxaluria type-1 Transplantation;85:1253-60.
3. 2008 ICRU reference dose in an era of intensity-modulated radiation therapy clinical trials: Correlation with planning target volume mean dose and suitability for intensity-modulated radiation therapy dose prescription Radiother Oncol; 89:347-52
4. 2008 Synergizing radiation therapy and immunotherapy for curing incurable cancers. Opportunities and challenges (Williston Park) ;22:1064-70; discussion 1075, 1080-1, 1084
5. 2008 Hepatic irradiation augments engraftment of donor cells following hepatocyte transplantation Hepatology ;49:258-67.
6. 2008 Identification of adult hepatic progenitor cells capable of repopulating injured rat liver Hepatology 47:636-647
7. 2008 Conformal radiotherapy for hepatocellular carcinoma Crit Rev Oncol Hematol
8. 2008 Tumor biology-guided radiotherapy treatment planning: gross tumor volume versus functional tumor volume. Semin Nucl Med 38:105-113
9. 2008 Hepatocellular carcinoma: radiation therapy Cancer J;14:111-6.
10. 2008 Hyperthermia on immune regulation: A temperature's story Cancer Lett;271:191-204
11. 2007 The Radiobiological rationale for hypofractionation of lung, liver and pancreas tumors Robotic Radiosurgery II: Treating Tumors that Move with Respiration
12. 2007 Prevention of hepatocyte allograft rejection in rats by transferring adenoviral early region 3 genes into donor cells Hepatology, 45: 755-766
13. 2007 A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers. J Biol Chem, 282:21477-86
14. 2007 Localized Hyperthermia Combined with Intratumoral Dendritic Cells Induces Systemic Antitumor Immunity Res 67(16):7798-7806
15. 2006 Noninvasive evaluation of liver repopulation by transplanted hepatocytes using 31P MRS imaging in mice Hepatology, 44: 1250-1258
16. 2006 Flt3L Therapy following Localized Tumor Irradiation Generates Long-Term Protective Immune Response in Metastatic Lung Cancer: Its Implication in Designing a Vaccination Strategy Oncology, 70: 245-254
17. 2005 Systemic administration of GMCSF combined with Localized tumor hyperthermia induces systemic antitumor immunity ASTRO 2005
18. 2005 omparison of intra-operative computer optimized and nomogram-based total implant activities in prostate I-125 seed implants Medical Physics, 32 (6): 1954-1955
19. 2005 Liver repopulation: a new concept of hepatocyte transplantation Surg Today, 35: 705-710
20. 2005 Role of cysteine residues in the function of human UDP glucuronosyltransferase isoform 1A1 (UGT1A1). Biochem J, 392: 685-692
21. 2005 Feasibility of hepatocyte transplantation-based therapies for primary hyperoxalurias. Amer. J. Nephrol., 25:161-70
22. 2005 Cell culture models and animal models of viral hepatitis II: hepatitis C. Lab Anim (NY), 34: 39-47
23. 2004 Regulation of hepatocellular bilirubin glucuronidation by protein Kinase C-catalyzed phosphorylation of UDP-glucuronosyltransrerase-1 (UGT1A1) Hepatology, 40 (4): 488A-488A
24. 2004 A preparative regimen of hepatic irradiation and hepatocyte growth factor (HGF) expression for liver repopulation by transplanted hepatocyte. Hepathology, 40 (4): 382A-382A
25. 2004 TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors J Clin Oncol, 22: 592-601
26. 2004 Bone marrow progenitors are not the source of expanding oval cells in injured liver Cells, 22:1049-61
27. 2004 Radiation damage protection by the benzyl styrl sulfone analog, Ex-Rad. International Journal of Radiation Oncology Biology Physics, 60 (1): S367-S368 2052
28. 2004 Radiation sensitization of prostate carcinoma cells by ONC 01910, a novel protein Kinase inhibitor and cell cycle modulator International Journal of Radiation Oncology Biology Physics, 60 (1): S341-S341
29. 2004 Cell culture and animal models of viral hepatitis Part I: hepatitis B. Lab Anim (NY), 33: 37-46
30. 2003 . Amerioration of histopathological lesions of liver and spleen of a mouse model of mucopolysaccharidosis VII after beta-glucuronidase gene transfer using a replication-defective simian virus 40 vector Hepatology, 38 (4): 153
31. 2003 Patterns of failure after the multimodality treatment of uterine papillary serous carcinoma Sood BM, Jones J, Gupta S, Khabele D, Guha C, Runowicz C, Goldberg G, Fields A, Anderson P, Vikram B
32. 2003 Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization Oncogene, 22: 6408-6423
33. 2003 Recombinant simian virus 40 requires lipid rafts, but not caveolae, to enter cells Molecular Therapy, 7 (5): 949
34. 2003 TNFerade, an adenovector carrying the transgene for human tumor necrosis factor alpha (TNF alpha), is well tolerated and has activity in patients with advanced solid tumors. A phase I study Annals of Surgical Oncology, 10 (1) Suppl.
35. 2003 Molecular therapies for viral hepatitis BioDrugs, 17: 81-91
36. 2003 Radiosensitization by Small Interfering RNAs (siRNA) targeting ATM Proc. ICRR, 2003
37. 2003 Bone marrow progenitors are not the normal source of oval cells in the injured liver FASEB Journal, 17 (5): A1064-A1064 Part 2 Suppl.
38. 2002 Angiostatin inhibits and regresses corneal neovascularization Arch Ophthalmol. 120: 1063-8
39. 2002 Hepatocyte Transplantation and Liver-Directed Gene Therapy. In: Molecular Pathogenesis of Cholestasis Chapter 25, Page 34 – 360
40. 2002 Radiation based approaches for liver repopulation. In: Hepatocyte Transplantation Hepatocyte Transplantation
41. 2002 Radiation based approaches for liver repopulation Falk Symposium Series, 126: 80-87.,
42. 2002 Predictive value of linear-quadratic model in the treatment of cervical cancer using high-dose-rate brachytherapy Int J Radiat Oncol Biol Phys. 54: 1377-87
43. 2002 Normal hepatocytes correct serum bilirubin after repopulation of Gunn rat liver subjected to irradiation/partial resection Hepatology. 36: 354-62.
44. 2002 A long-awaited small animal model for hepatitis C J Hepatol. 36: 447-9.
45. 2001 A novel therapeutic strategy for hepatocellular carcinoma: Immunomodulation by Flt3-Ligand (Flt3L) following whole liver irradiation and radio-inducible HSV-TK gene therapy. Int J Rad Onc Biol Phys. (2001) 51: 189A
46. 2001 Flt3-ligand in combination with CD40-ligand gene transfer following radiation-inducible HSV-TK gene therapy improves survival in mice with diffuse hepatocellular carcinoma Hepatology (2001) 34 (4): 144A.
47. 2001 Selective hepatic lobar repopulation by transplanted hepatocytes after ligation of a portal vein branch and preparative hepatic irradiation Hepatology (2001) 34 (4): 153A
48. 2001 Radiation-based approaches to hepatocyte repopulation Falk Foundation on “Hepatocyte Transplantation” Symposium Proceedings (2001).
49. 2001 Chemokine Receptor-7 on dendritic cells (DC) is induced after interaction with irradiated prostate tumor cells: Effect of irradiated cells on DC maturation. Int J Rad Onc Biol Phys. (2001) 51: 233A
50. 2001 Effect of ionizing radiation (IR) on expression of apoptosis related genes in a rat salivary gland derived cell line: Implication of Bcl-2 gene therapy in xerostomia Int J Rad Onc Biol Phys. (2001) 51: 1010A.
51. 2001 Recombinant SV40 vector-modified transfer of ß-glucuronidase gene into mucopolysaccharidosis Type VII mice. Molecular Therapy (2001) 3: 647A
52. 2001 Clinical protocol. An open-label, phase I, dose-escalation study of tumor necrosis factor-alpha (TNFerade Biologic) gene transfer with radiation therapy for locally advanced, recurrent, or metastatic solid tumors Hum Gene Ther. 12: 1109-31
53. 2001 Hepatocyte-based gene therapy J Hepatobiliary Pancreat Surg. 8: 51-7
54. 2001 Liver irradiation: a potential preparative regimen for hepatocyte transplantation Int J Radiat Oncol Biol Phys. 49: 451-457
55. 2001 Amplification of engrafted hepatocytes by preparative manipulation of the host liver Artif Organs. 25: 522-8
56. 2000 Recombinant adenoassociated virus in cancer gene therapy Hepatol. 32: 1031-4
57. 2000 Local irradiation and concomitant cytokines as an in situ autologous tumor vaccination strategy Int J Radiat Oncol Biol Phys. 48: 284-285
58. 2000 A preparative regimen for massive repopulation of the liver by transplanted hepatocytes consisting of hepatic irradiation and triiodothyronine (T3) therapy: Amelioration of jaundice in Gunn rats Hepatology (2000) 32: 206
59. 2000 Adenovirus-mediated antisense ATM gene transfer sensitizes prostate cancer cells to radiation Cancer Gene Ther. 7: 1307-14
60. 2000 Antisense ATM gene therapy: a strategy to increase the radiosensitivity of human tumors Gene Ther. 7: 852-8
61. 2000 Reversibly immortalized human hepatocytes: an eternal fountain of liver support?, Hepatology. 32: 440-1
62. 2000 Local irradiation and concomitant cytokines as an in situ autologous tumor vaccination strategy 1.      In J Rad Onc Biol Phys. 48: 284-5.
63. 2000 Hepatocyte transplantation ameliorates radiation-induced liver damage and increases survival after partial hepatic resection and irradiation Int J Rad Onc Biol Phys. (2000) 46: 107
64. 2000 Local radiotherapy (RT) in combination with adjuvant cytokines as a novel treatment against distant metastases: Strategies to generate an effective systemic response by harnessing tumor antigens released by RT Int J Rad Onc Biol Phys. (2000) 46: 85
65. 2000 Antisense ATM gene therapy: A strategy to increase the radiosensitivity of human tumors Int J Rad Onc Biol Phys. (2000) 46: 241
66. 2000 Local irradiation and concomitant cytokines as an in situ autologous tumor vaccination strategy Int J Rad Onc Biol Phys 48: 2040A
67. 2000 Regulated Fas-mediated apoptosis of host hepatocytes along with hepatic irradiation results in preferential proliferation of hepatocytes transplantaed in rat liver Hepatology (2000) 32: 211
68. 1999 Complete, long-term normalization of serum bilirubin levels in Gunn rats after hepatocyte transplantation following partial hepatectomy and liver irradiation Hepatology (1999) 30: 108
69. 1999 Internal mammary nodal metastases from breast cancer detected by scintimammography Clin Nucl Med. 24: 203-4
70. 1999 Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer Cancer Res. 59: 6028-32
71. 1999 Amelioration of radiation-induced liver damage in partially hepatectomized rats by hepatocyte transplantation Cancer Res. 59: 5871-4
72. 1998 Hepatocyte transplantation repopulates the liver and increases the survival after partial hepatectomy and whole liver irradiation in F344 rats DDW (1998): 918
73. 1998 Attenuation of ATM protein expression increases radiosensitivity in human glioblastoma (GBM) cells AACR Proceedings, (1998) 39:1909
74. 1998 Cancer Immunotherapy: How to bell the cat?, Eisntein Quart. J. Biol. Med. 15: 47-48
75. 1998 Flt3 Ligand (Flt3L) combined with radiation therapy (RT) prolongs survival in a murine model of metastatic lung cancer Cancer Vaccine Week (sponsored by Cancer Research Institute), Oct 5-9
76. 1997 Hepatocyte transplantation improves early survival after partial hepatic resection and irradiation Int J. of Rad. Onc. Biol. And Phys. (1997) 39 (2): 2083
77. 1997 J. Massive repopulation of rat liver by transplantation of hepatocytes into specific lobes of the liver and ligation of portal vein branches to other lobes Transplantation. 64: 8-13
78. 1996 A modified DOP-PCR method to obtain high molecular size amplified DNA from microdissected archival tumor tissues Int J. of Rad. Onc. Biol. And Phys. (1996) 36 (1): 2010
79. 1996 Protection of rat primary hepatocytes from radiation-induced apoptosis by hepatocyte growth factor (HGF) Int J. of Rad. Onc. Biol. And Phys. (1996) 36: 2174.
80. 1995 Can a guest liver bring the gift of a gene to disarm a hostile host? Hepatology. 22: 1888-90
81. 1995 Regulation of human Gc (vitamin D--binding) protein levels: hormonal and cytokine control of gene expression in vitro Hepatology. 21: 1675-81
82. 1993 The vitamin D-binding protein gene: quantitation of amplified nucleic acids by ELISA Biotechniques. 15: 706-13


4th Annual Pharma R&D Asia Congress
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