9th Annual Biomarkers Congress

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Grant Support

Start year End year Title Source Position
1. 2009 2009 secretory clusterin (sCLU) pathway: Mediator of a low-dose IR-Inducible bystander effect Department of Energy (DOE) DE-FG02-06ER64186 PI: Boothman, DA
2. 2009 2009 1 R01 CA102792-01 NCI/NIH Administrative Supplement PI: Boothman
3. 2009 2009 Genetic instability in cancer NCI/NIH GO Grant PI: Gardner
4. 2009 Structure/function of human KUB5/Hera NCI/NIH Challenge Grant PI: Boothman
5. 2009 Role of senescent cells in radioresistant human cancer microenvironment DoD Post-doctoral Fellowship (X81XWH-09-1-0168) in Prostate Cancer. Student: Xiuquan Luo
6. 2009 Mediator of a Low Dose IR-Inducible Bystander Effect Department of Energy (DOE), DE-FG-022179-18-21 P.I.: Boothman, D. A
7. 2006 2009 Mechanisms of IGF-1 induction after ionizing radiation (IR). DoD Pre-doctoral Fellowship (W81XWH-06-0748) In Breast Cancer. Student PI: Eva Cataldo
8. 2005 2009 Role of apoptosis inducing factor (AIF) in ß-lapachone-mediated cell death responses DoD Prostate Cancer Program Idea Award (W81XWH-06-1-0198) PI: David A. Boothman
9. 2005 2009 Ms Rommel assumed grant for one year. No overlap. DoD Predoctoral Award, W81XWH-05-1-0248 student: Kathryn Reinicke/Amy Rommel
10. 2008 Role of Ku70 binding protein 5 (KUB5) in DNA repair and genetic instability NCI/NHI, R01 PI: Boothman
11. 2007 2008 Role of reactive free radicals in ß-lapachone-dependent cell death DoD Pre-doctoral Fellowship, W81XWH-05-1-0248 in Breast Cancer Student: Amy Rommel
12. 2007 Use of ß-lapachone for the treatment of human prostate cancer cells DoD Post-doctoral Fellowship (X81XWH-07-1-0078) in Prostate Cancer. Student: Ying Dong
13. 2004 2007 This student is expected to graduate DoD Pre-doctoral Award, W81XWH-04-1-0301 student: Melissa Bentle
14. 2004 2007 Use of ß-lapachone-encapsulated millirods for improved therapy of prostate cancer Department of Defense (DoD) Idea Award, W81XWH-04-1-0164, Prostate Cancer Award Mechanism. PI: Boothman, David, A.
15. 2001 2006 Cancer Center Core Grant, CWRU and Univ. Hospitals NIH/NCI P30, CA43703-12 P.I. Gerson, S
16. 2001 2006 Use of ß-lapachone for non-small cell lung cancer therapy NIH/R01, (1 R01 CA102792-01 PI: Boothman, D.A
17. 2001 2005 Exploiting NQO1 for enhanced radiotherapy of breast cancer using ß-lapachone NCI/NIH R01 (CA92250-01 PI: D. A. Boothman
18. 2001 2005 Clusterin: A Low Dose IR-Inducible Molecular Switch Between Life and Death Department of Energy, DE-FG-022179-12-15 P.I. Boothman, D. A
19. 2001 2004 Breast Cancer Research Initiative Department of Defense, (DOD, DAMD-17-01-1-0196 Student: Kostantin Leskov
20. 2001 2004 Exploiting NQO1, a radiation-inducible enzyme, using ß-lapachone for improved radiotherapy of prostate cancer Department of Defense Prostate Cancer Initiative P.I. Boothman, D. A
21. 2001 2004 Breast Cancer Research Initiative Department of Defense, (DOD, DAMD-01-1-0194 Student: Tracy Criswell
22. 1999 2004 Role of DNA mismatch repair in FdUrd-mediated cytotoxicity National Institutes of Health R01 (CA-83196-01 P.I.: David A. Boothman
23. 2003 Use of ß-lapachone for non-small cell lung cancer therapy NIH/R01, (1 R01 CA102792-01 PI: Boothman, D.A
24. 2001 2003 Research Oncology Training Grant, Pre-doctoral Fellowship NIH/NCI/Ireland Comprehensive Cancer Center Student: Kate Reinicke
25. 2000 2003 Mismatch repair defects and human tumor radiosensitization 31. NIH/NCI R01, CA84578-02 P.I.: Kinsella, T.J
26. 2000 2003 Breast Cancer Research Initiative Department of Defense (DOD, DAMD 17-00-1-0194 Student Colleen Tagliarino
27. 2000 2003 Breast Cancer Research Initiative Department of Defense (DOD, DAMD 17-01-0194 Student: Mark Wagner
28. 1998 2003 Functions of xip8, an X-ray-inducible Ku70 binding protein National Institutes of Health (1R01CA/ES78530-1) P.I.: David A. Boothman
29. 2001 2002 Modulation of p53 for improved therapy of glioma Brain Tumor Society Awards Student
30. 2000 2001 Topoisomerase I-mediated Apoptosis in Breast Cancer Pre-doctoral fellowship Student: Tracy Criswell
31. 1998 2001 Nuclear apoJ: An X-ray-inducible cell death signal Department of Energy (DE-FG02-99EQ62724)-09-12 P.I.: David A. Boothman
32. 1998 2001 Cloning A Novel Apoptotic Protease Activated in Human Breast Cancer Cells After Poisoning Topoisomerase I Department of Defense (Breast Cancer Initiative, DAMD17-98-1-8260), PI: David A. Boothman
33. 1997 2000 Topoisomerase I-mediated Apoptosis in Breast Cancer United States Army Breast Cancer Initiative PI: David A. Boothman
34. 1997 1998 Role of Cell Cycle Regulation and the DNA Mismatch Repair Gene, hMLH1, in Adaptive Survival Responses Department of Energy, DE-FG02-93ER61707-06-09 P.I.: David A. Boothman
35. 1996 1998 Use of ß-Lapachone Analogs Against Human Breast Cancer UWCCC Breast Cancer Basic Research Fund P.I.: David A. Boothman
36. 1995 1998 Modulation of Retinoblastoma Control Proteins After X-Rays National Institutes of Health (RO1), R01-CAEY67995-01 P.I.: David A. Boothman
37. 1995 1997 Topoisomerase I-mediated apoptosis in human prostate cancer cells CapCure Foundation P.I.: David A. Boothman
38. 1994 1997 Role of X-Ray-Induced Transcripts and Altered Cell Cycle Regulation In Adaptive Survival Responses Following X-Rays: Potential Role of Mismatch, Excision, and Recombinational DNA Repair Systems Department of Energy, DE-FG02-93ER61707-03-06 P.I.: David A. Boothman
39. 1996 1995 Use of compound, CPR1006, to augment radiation therapy Clarion Pharmaceuticals P.I.: David A. Boothman
40. 1992 1996 Cloning an X-Ray-Induced Protein In Radioresistant Cells National Institutes of Health (RO1), P.I.: David A. Boothman
41. 1995 Use of ß-lapachone and its derivatives against human breast and prostate cancers Breast Cancer Fund P.I.: David A. Boothman
42. 1991 1995 Role of Topoisomerase I In DNA Repair American Cancer Society, PDT-413/DHP-90A P.I.: David A. Boothman
43. 1991 1995 Molecular Cloning Of X-Ray-Induced Genes and Proteins: Induction of Transcriptional Machinery American Cancer Society, EDT-45 P.I.: David A. Boothman
44. 1993 1994 Gene Radiotherapy Using X-Ray-Responsive Elements University of Wisconsin Comprehensive Cancer Center, DeMerrit Foundation Grant P.I.: David A. Boothman
45. 1991 1994 Role of X-Ray-Induced Transcripts In Adaptive Survival Responses Following X-Rays Department of Energy, DE-FG02-93ER61707-01-03 P.I.: David A. Boothman
46. 1991 1992 Use of Topoisomerase I Inhibitors For Chemotherapy National Institutes of Health P.I.: Arthur B. Pardee
47. 1990 1991 Role of Topoisomerase I In DNA Repair Milheim Foundation P.I.: David A. Boothman
48. 1989 1990 X-Ray-Inducible Genes and Proteins In Cancer-prone Compared To Normal Human Cells Biomedical Research Support Grant, ACS P.I.: David A. Boothman
49. 1988 Molecular Cloning of X-Ray-induced genes Biomedical Research Support Grant, NIH. P.I.: Arthur B. Pardee
50. 1988 Anticarcinogenesis testing using Topoisomerase I active Drugs Biomedical Research Support Grant, NIH. P.I.: Arthur B. Pardee


4th Annual Pharma R&D Asia Congress
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