9th Annual Biomarkers Congress

View Profile

Peer Reviewed Papers, Books, Chapters

Year Title Citation Authors
1. 2012 Identification of an inhibitory ganglioside responsible for immune suppression by ovarian cancer Cancer Res. Accepted
2. 2012 . A new method to determine antigen-specific CD8+ T cell activity in vivo by hydrodynamic injection. Biomolecules. 2, 23-33.
3. 2011 nvariant NKT cells recognize glycolipids from pathogenic gram-positive bacteria. Nat. Immunol. 12: 966-974.
4. 2011 Functional Invariant NKT Cells in Pig Lungs Regulate the Airway Hyperreactivity: A Potential Animal Model. J. Clin. Immunol. 31: 228-239.
5. 2011 A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design. Nat. Med. 17: 1602-1609.
6. 2010 Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by V{alpha}14i NKT Cells. J. Immunol. 184: 141-153.
7. 2010 Replacing adenoviral vector HVR1 with a malaria B cell epitope improves immunogenicity and circumvents pre-existing immunity to adenovirus in mice. J. Clin. Inv. 120: 3688-3701.
8. 2010 Design of a novel CD1d-binding NKT cell ligand as a vaccine adjuvant. Proc. Natl. Acad. Sci. USA. 107: 13010-13015.
9. 2010 Re-evaluating the role of T cells for the development of T cell-based, malaria vaccine . Exp. Parasitol. 126: 421-425. Review.
10. 2010 A CD1d-dependent antagonist inhibits the activation of iNKT cells and prevents development of allergen-induced airway hyperreactivity. J. Immunol. 184: 2107-15.
11. 2010 A multifactorial mechanism in the superior anti-malarial activity of a-C-GalCer. J. Biomed. Biotech. 2010: 283612: 1-11.
12. 2010 A double-edged sword: The Role of NKT cells in Malaria and HIV Infection and Immunity. Seminar Immunol. 22: 87-96. Review.
13. 2009 Quantifying cytokine production by epitope-specific, HLA-restricted CD8+ T cells after stimulation by immobilized HLA-A2:Ig dimeric proteins. Scan. J. Immunol. 70: 415-422.
14. 2009 Invariant TCR rather than CD1d shapes the preferential activities of C-glycoside analogues against human versus murine iNKT cells. J. Immunol. 183: 4415-4421.
15. 2009 Alpha-C-Galactosylceramide as an adjuvant for a live attenuated influenza virus vaccine. Vaccine 27: 3766-3774.
16. 2009 Identification of C-glycoside analogues that display a potent activity against human NKT cells. Immunology 127: 216-225.
17. 2009 Chapter 32: Malaria In: Satoskar A, Simon G, Hotez P and Tsuji, M. eds. Medical Parasitology. Landes Bioscience. Austin, TX. 237-247. ISBN: 978-1-57059-695-7
18. 2009 Chapter 26: Toxoplasmosis In: Satoskar A, Simon G, Hotez P and Tsuji, M. eds. Medical Parasitology. Landes Bioscience. Austin, TX. 190-194. ISBN: 978-1-57059-695-7
19. 2009 Human CD1 dimeric proteins as indispensable tools for research on CD1-binding lipids and CD1-restricted T cells J. Immunol. Methods 345: 49-59.
20. 2008 Development of a Microarray System to Measure the Glycolipids Binding Properties with CD1d Proteins. J. Am. Chem. Soc. 130: 12348-12354.
21. 2008 Enhancement of HIV DNA vaccine immunogenicity by the NKT cell ligand α-galactosylceramide Vaccine 26: 1807-1816.
22. 2008 Activation of iNKT cells ameliorates experimental ocular autoimmunity by a mechanism involving innate IFN-γ production and dampening of the adaptive Th1 and Th17 responses. J. Immunol. 181: 4791-4797.
23. 2008 Cognitive dysfunction in mice infected with Plasmodium berghei ANKA J. Infect. Dis. 197:1621-1627.
24. 2007 Percentage and function of NKT cells, a potential anti-HIV effector cell, are preserved by beginning HAART during acute and early HIV-1 Infection Int. Immunol. 19: 943-951.
25. 2007 The natural killer T-cell ligand alpha-C-galactosylceramide promotes ovarian cancer survival by dual regulation of the adaptive host immunity Gyn Oncology 104: S21.
26. 2007 Combined NKT cell-based immunotherapy eradicates established tumors in mice Cancer Res. 67: 7495-7504
27. 2007 Long-term IFN-g Dependent Efficacy of Activated Va14i Natural Killer T cells in the Prevention of Collagen-Induced Arthritis J. Immunol. 179: 2300-2309.
28. 2006 The glycolipid α-C-GalCer is a distinct inducer of dendritic cell maturation and both innate and adaptive T cell immunity in mice. Proc.Natl.Acad.Sci. USA. 103:11252-11257.
29. 2006 Recombinant human adenovirus serotype 35-based malaria vaccine: Immunogenicity and protection against Plasmodium yoelii in mice. Infect. Immun. 74: 313-320.
30. 2006 Endothelin in a Murine Model of Cerebral Malaria Exp. Biol. Med. 231: 1176-1181.
31. 2006 Long-term IFN-gamma dependent efficacy of activated V alpha 14I natural killer T-cells in the prevention of collagen-induced arthritis. Clin. Immunol. 119: S62
32. 2006 E and Z αC-Galactosylceramides via Julia-Lythgoe-Kocienski Chemistry: A Test of the Receptor Binding Model for Glycolipid Immunostimulants. Chem. Bio. Chem. 7: 1017-1022.
33. 2006 Structure-Based Discovery of Glycolipids for CD1d-mediated NKT cell activation: Tuning the Adjuvant versus Immunosuppression Activity. J. Am. Chem. Soc. 128: 9022-9023.
34. 2006 Pre-clinical studies towards rAd35-based malaria vaccines Am. J. Trop. Med. Hyg. 75: 304.
35. 2006 α-C-Galactosylceramides: Synthesis and Immunology Acc. Chem. Res. 39: 692-701. Review.
36. 2006 Long-term IFN-gamma dependent efficacy of activated valpha141 natural killer T cells in the prevention of collagen-induced arthritis Annals Rheum. Dis. 2006; 65: 141
37. 2006 NKT cells recognize diacylglycerol antigens from pathogenic bacteria. Nat. Immunol. 7: 978-986.
38. 2006 Glycolipids and phospholipids as natural CD1d-binding NKT cell ligands. Cell. Mol. Life Sci. 63:1889-1898. Review.
39. 2005 Glycolipid-presentation to natural killer T cells differs in an organ-dependent fashion. Proc. Natl. Acad. Sci. USA. 102: 1127-1132.
40. 2005 Reduced cerebral blood flow and N-acetyl aspartate in a murine model of cerebral malaria. Parasitol. Res. 96: 302 - 307.
41. 2005 Recognition of bacterial glycosphingolipids by natural killer T cells. Nature 434: 520 - 525.
42. 2005 Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides. Bioorg. Med. Chem. 13:2907-2916.
43. 2005 Novel bacterial glycolipids and analogues as antigens for CD1d-restricted NKT cells Proc. Natl. Acad. Sci. USA. 102: 1352 -1356.
44. 2004 The C-glycoside analogue of the immunostimulant alpha-galactosylceramide (KRN7000): synthesis and striking enhancement of activity. Angew. Chem. Int. Ed. Eng. 19: 3818-3822.
45. 2004 Enhanced protective immunity against malaria by vaccination with a recombinant adenovirus encoding the circumsporozoite protein of Plasmodium lacking the GPI-anchoring motif Vaccine 22: 3575-3584.
46. 2004 Efficient Synthesis of alpha-C-Galactosyl Ceramide Immunostimulants: Use of Ethylene-Promoted Olefin Cross-Metathesis Org. Lett. 6: 4077-4080.
47. 2003 Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand a-galactosylceramide. J. Exp. Med. 198: 1631-1641.
48. 2003 The dendritic cell-specific chemokine DC-CK1 enhances protective cell-mediated immunity to murine malaria J. Immunol. 170: 3195-3203.
49. 2003 T cells as mediators of protective immunity against malaria liver stages. Trends in Parasitol. 19: 88-93. Review.
50. 2003 The role of natural killer T cells and other T cell subsets against infection by liver stages of malaria parasites. Microbes and Inf. 5: 499-506. Review.
51. 2002 The involvement of CD1d-restricted NKT cells in infectious processes Revision 21: 145-155. Review.
52. 2002 Assessing antigen-specific CD4+ and CD8+ T cell responses in mice after immunization with recombinant viruses. In: Malaria Methods and Protocols. Methods in Molecular Medicine. New Jersey: Humana Press Inc. Vol. 72: 361-367.
53. 2002 A novel immune mechanism against malaria: The involvement of NKT cells. Inf. Infl. Immun. 32: 2-9. In Japanese. Review.
54. 2002 The natural killer T cell ligand α-galactosylceramide enhances protective immunity induced by malaria vaccines J. Exp. Med. 195: 617-624.
55. 2001 Detection of malaria liver-stages in mice infected through the bite of a single Anopheles mosquito using a highly sensitive real-time PCR Int. J. Parasitol. 31: 1499-1502.
56. 2001 Progress towards a malaria vaccine: Efficient induction of anti-malaria immunity. Biol. Chemistry 382: 553-570. Review.
57. 2001 Peptide-based subunit vaccines against pre-erythrocytic stages of malaria parasites. Mol. Immunol. 38; 433-442. Review.
58. 2001 Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen. Proc. Natl. Acad. Sci. USA. 98: 11491-11496.
59. 2000 Multifactorial protective mechanisms to limit viral replication in the lung of mice during primary murine cytomegalovirus infection. Viral. Immunol. 13: 287-295.
60. 2000 Malaria Vaccine Development: Various immunization regimens for efficient induction of protective anti-malaria immunity Science and Culture 52: 288-304. Review.
61. 2000 Host-virus interactions during malaria infection in hepatitis B virus transgenic mice J. Exp. Med. 192: 529-536.
62. 2000 Innate response of murine γδ T cells to the synthetic polypeptide, poly Glu50Tyr50 J. Immunol. 165: 1790-1798.
63. 2000 α-GalCer-activated Vα14 natural killer T cells mediate protection against murine malaria Proc. Natl. Acad. Sci. USA. 97: 8461-8466.
64. 2000 Immunization and infection change the number of RAG expressing B cells in the periphery by altering immature lymphocyte production. J. Exp. Med. 191: 2113-2120.
65. 2000 Cutting Edge: The IgG response to the circumsporozoite protein is MHC class II-dependent and CD1d-independent: Exploring the role of GPIs in NKT cell activation and antimalarial responses J. Immunol. 164: 5005-5009.
66. 2000 gamma/delta T cells are a component of early immunity against preerythrocytic malaria parasites Inf. Immun. 68: 2224-2230.
67. 2000 Interferon-gamma Independent CD8+ T cell-mediated protective anti-malaria immunity induced by recombinant adenovirus Parasite Immunol. 22: 157-160.
68. 1999 Phenotypic and functional characterization of CD8+ T cell clones specific for a mouse cytomegalovirus epitope   Virology 155: 40-49.
69. 1999 Protective role of NKT cells against liver stages of malaria infection in mice. Am. J. Trop. Med. Hyg. 61: 341
70. 1999 Immunogenic properties of the merozoite surface proteint 1 gene of Plasmodium vivax. Vaccine 17: 2959-2968.
71. 1999 Current status of malaria vaccine development. Prog. Med. 191: 88-92. In Japanese. Review.
72. 1999 IFN‑γ but not NO nor NK cells are critical for the protective immunity to infection with blood‑stage Plasmodium berghei XAT Inf. Immun. 67: 2349-56.
73. 1998 Immunity and parasitic diseases Today’s Therapy 21: 1-2. In Japanese. Review.
74. 1998 Recombinant viruses expressing a human malaria antigen elicited protective cellular and humoral responses in mice Proc. Natl. Acad. Sci. USA. 95: 3954-9.
75. 1998 Recombinant Sindbis viruses expressing a cytotoxic T lymphocyte epitope of a malaria parasite or of an influenza virus elicit protection against the corresponding pathogen in mice J. Virol. 72: 6907-10.
76. 1998 Efficient induction of protective anti-malaria immunity by recombinant adenovirus. Vaccine 16: 1812-17.
77. 1997 Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cell-mediated protective immunity against malaria J. Immunol. 158: 1268-74.
78. 1996 Phenotypic and functional properties of murine g/d T cell clones derived from malaria immunized, ab T cell-deficient mice. Int. Immunol. 8: 359-66.
79. 1996 Characterization of in vivo primary and secondary CD8+ T cell responses induced by recombinant influenza and vaccinia viruses. Cell Immunol. 173: 96-107.
80. 1996 Plasmodium yoelii: Peptide immunization induces protective CD4+ T cells against a previously unrecognized cryptic epitope of the circumsporozoite protein Exp. Parasitol. 84: 223-30.
81. 1996 Differential infectivity of Plasmodium berghei and P. yoelii in vivo is established primarily after sporozoite invasion of liver cells Mol. Bio. Parasitol. 77: 7-17.
82. 1996 Immunity to malaria: Protective immune mechanisms mediated by T cells. Inf. Infl. Immun. 26: 2-9. In Japanese. Review
83. 1995 Murine epidermal Vg5/Vd1-TCR+ T cells respond to B cell lines and lipopolysaccharides. J. Invest. Dermatology 105: 58-61.
84. 1995 Development of anti-malaria immunity in mice lacking interferon- receptor. J. Immunol. 154: 5338-44.
85. 1994 Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites. Parasitol. Res. 80: 16-21.
86. 1994 Tcells contribute to immunity against the liver stages of malaria in a/b T cell-deficient mice. Proc. Natl. Acad. Sci. USA. 91: 345-9.
87. 1993 Pfs 2400 can mediate antibody-dependent malaria transmission inhibition and may be the Pasmodium falciparum 11.1 gene product J. Exp. Med. 177: 273-81.
88. 1992 Monoclonal antibodies recognize a processing dependent epitope present in the mature CS protein of various plasmodial species. Parasite Immunol. 14: 457-69.
89. 1991 Immunity to malaria: Sporozoite vaccine development. Inf. Infl. Immun. 21: 149-56. In Japanese. Review.
90. 1990 The development of malaria vaccine: Induction of T cells is the main stream of sporozoite vaccine develoment Prog. Med. 152: 160. In Japanese. Review.
91. 1990 CD4+ cytolytic T cell clone confers protection against murine malaria. J. Exp. Med. 172:1353-7.
92. 1988 Establishment of murine T cell lines and clones, hybridomas and transfectomas In: Kaufman S, Kabelitz, D. eds. Methods in Microbiology. New York, Academic Press, 25: 205-235
93. 1987 Autoimmunity and immune circuit In: Wigzell H, Kyogoku M. eds. New Horizons in Animal Models for Autoimmune Disease. New York: Academic Press, 341-347.
94. 1987 Introducing Immunology, Nankodo Co., Ltd., Tokyo 96.   Originally edited by Staines, N., Brostoff, J.and James, K. Gower Medical Publishing Ltd., London (1985).
95. 1987 Shared idiotopes between anti-class II monoclonal antibodies and major histocompatibility complex restriction site of T cells Eur. J. Immunol. 117: 675-81.
96. 1986 The immune circuit: Somatic generation of epitopes involved in the mutual recognition by different subsets of T cells In: Reichlin M, Capra JD, eds. Idiotypes. New York: Academic Press, 249-261.
97. 1986 Adaptive construction of the immune circuit Prog Immunol VI 427-437.

4th Annual Pharma R&D Asia Congress
About Us | Privacy Policy | Site Map | FAQs | Advertise With Us | Community
BiotechScienceNews.com promotes research and ranks life scientists working in the life science spectrum involving biotechnology,
drug discovery, genomics, microbiology, neuroscience, medicine, pharmacology, cell biology, and molecular biology.