9th Annual Biomarkers Congress

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Peer Reviewed Papers, Books, Chapters

Year Title Citation Authors
1. 2010 Quantitative evaluation of protein expression as a function of tissue microarray core diameter: is a large (1.5 mm) core better than a small (0.6 mm) core? Arch Pathol Lab Med 2010;134(4):613-9.
2. 2010 The ERalpha coactivator, HER4/4ICD, regulates progesterone receptor expression in normal and malignant breast epithelium Molecular cancer 9, 150
3. 2010 PMCA2 regulates apoptosis during mammary gland involution and predicts outcome in breast cancer Proc Natl Acad Sci U S A 107, 11405-11410.
4. 2010 High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology BMC Cancer 10:186
5. 2010 Benefits of biomarker selection and clinico-pathological covariate inclusion in breast cancer prognostic models Breast Cancer Research 12:R66
6. 2010 Growth factor receptor-bound protein-7 (Grb7) as a prognostic marker and therapeutic target in breast cancer Ann Oncol 21, 466-473.
7. 2010 Antibody validation. BioTechniques 48, 197-209
8. 2010 Multiplexed assessment of the Southwest Oncology Group-directed Intergroup Breast Cancer Trial S9313 by AQUA shows that both high and low levels of HER2 are associated with poor outcome. Am J Pathol 176, 1639-1647
9. 2010 Quantitative expression of VEGF, VEGF-R1, VEGF-R2, and VEGF-R3 in melanoma tissue microarrays Hum Pathol 41, 375-384
10. 2010 Analytic variability in immunohistochemistry biomarker studies Cancer Epidemiol Biomarkers Prev, 19(4):982-991
11. 2010 Nuclear localization of signal transducer and activator of transcription 3 in head and neck squamous cell carcinoma is associated with a better prognosis Clin Cancer Res. 16:2427-34
12. 2010 High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology BMC Cancer. 10:186
13. 2010 Automated analysis of tissue microarrays Methods Mol Biol 664:151-162
14. 2010 Is ALDH1 a good method for definition of breast cancer stem cells? Breast Cancer Res Treat;123(1):109-11.
15. 2010 Biomarkers: the useful and the not so useful--an assessment of molecular prognostic markers for cutaneous melanoma. The Journal of Investigative Dermatology;130(8):1971-87
16. 2010 What Are the Biggest Challenges and Opportunities for Biorepositories in the Next Three to Five Years? Biopreservation and Biobanking., 8(2): 81-88.
17. 2009 Quantitative assessment of tissue biomarkers and construction of a model to predict outcome in breast cancer using multiple imputation Cancer informatics;7:29-40.
18. 2009 The semaphorin 7A receptor Plexin C1 is lost during melanoma metastasis The American Journal of Dermatopathology;31(2):177-81
19. 2009 Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR/Her2 inhibitor in non-small-cell lung cancer cells Br J Cancer;100(6):941-9.
20. 2009 The function, proteolytic processing, and histopathology of Met in cancer Adv Cancer Res, 103:1-23
21. 2009 Tissue Biomarkers for Prognosis in Cutaneous Melanoma: A Systematic Review and Meta-analysis . J Natl Cancer Inst. 101(7):452-474
22. 2009 Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer Science;323(5918):1218-22.
23. 2009 Expression of sorafenib targets in melanoma patients treated with carboplatin, paclitaxel and sorafenib. Clin Cancer Res;15(3):1076-85
24. 2009 Melanoma Prognostic Model Using Tissue Microarrays and Genetic Algorithms J Clin Oncol, 27(34):5772-80
25. 2009 DNA Hypermethylation of ESR1 and PGR in Breast Cancer: Pathologic and Epidemiologic Associations Cancer Epidemiol Biomarkers Prev, 18:3036-3043
26. 2009 C-Raf is associated with disease progression and cell proliferation in a subset of melanomas Clin Cancer Res, 15:5704-5713
27. 2009 Growth factor receptor-bound protein-7 (Grb7) as a prognostic marker and therapeutic target in breast cancer Ann Oncol
28. 2009 Defining molecular phenotypes of human papillomavirus-associated oropharyngeal squamous cell carcinoma: validation of three-class hypothesis Otolaryngol Head Neck Surg, 141:382-389
29. 2009 Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features Proc Natl Acad Sci U S A, 106:13820-13825
30. 2009 GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer Nature, 459:1085-1090
31. 2009 High expression of mammalian target of rapamycin is associated with better outcome for patients with early stage lung adenocarcinoma Clin Cancer Res, 15:4157-4164
32. 2009 Quantitative, fluorescence-based in-situ assessment of protein expression Methods Mol Biol;520:163-75
33. 2009 Gab2-mediated signaling promotes melanoma metastasis Am J Pathol;174(4):1524-33
34. 2009 Quantitative multiplexed analysis of ErbB family coexpression for primary breast cancer prognosis in a large retrospective cohort Cancer. 115:2400-2409
35. 2009 Phosphatidylinositol-3-Kinase as a Therapeutic Target in Melanoma Clin Cancer Res. 15:3029-3036
36. 2009 Microvessel area using automated image analysis is reproducible and is associated with prognosis in breast cancer Hum Pathol;40(2):156-65.
37. 2009 Thyroid transcription factor 1 is an independent prognostic factor for patients with stage I lung adenocarcinoma J Clin Oncol;27(2):271-8.
38. 2009 Activated Wnt/ss-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model Proc Natl Acad Sci U S A.: 106(4): 1193-1198
39. 2008 High levels of vascular endothelial growth factor and its receptors (VEGFR-1, VEGFR-2, neuropilin-1) are associated with worse outcome in breast cancer Hum Pathol;39(12):1835-43
40. 2008 Correlates and determinants of nuclear epidermal growth factor receptor content in an oropharyngeal cancer tissue microarray Cancer Epidemiol Biomarkers Prev 17, 1486-1492
41. 2008 Comparison of quantitative immunofluorescence with conventional methods for HER2/neu testing with respect to response to trastuzumab therapy in metastatic breast cancer Arch Pathol Lab Med;132(10):1635-47.
42. 2008 AQUA analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma Arch Pathol Lab Med;132(11):1746-52
43. 2008 Prognostic significance of cadherin-based adhesion molecules in cutaneous malignant melanoma Cancer Epidemiol Biomarkers Prev, 17:949-958
44. 2008 HSP90 as a marker of progression in melanoma Ann Oncol 9(3):590-4
45. 2008 A decade of tissue microarrays: progress in the discovery and validation of cancer biomarkers. J Clin Oncol;26(34):5630-7
46. 2008 Fine-needle aspiration of follicular adenoma versus parathyroid adenoma: the utility of multispectral imaging in differentiating lesions with subtle cytomorphologic differences Cancer. 2008 Feb 25;114(1):22-6
47. 2008 Expression of Aurora A (but not Aurora B) is predictive of survival in breast cancer . Clin Cancer Res;14(14):4455-62
48. 2008 Correlates and determinants of nuclear epidermal growth factor receptor content in an oropharyngeal cancer tissue microarray Cancer Epidemiol Biomarkers Prev;17(6):1486-92.
49. 2008 Genomic analysis of estrogen cascade reveals histone variant H2A.Z associated with breast cancer progression. Mol Syst Biol 4, 188.
50. 2008 Expression patterns and prognostic value of Bag-1 and Bcl-2 in breast cancer Breast Cancer Res 10(2), R35.
51. 2008 Estrogen receptor co-activator (AIB1) protein expression by automated quantitative analysis (AQUA) in a breast cancer tissue microarray and association with patient outcome Breast Cancer Res Treat.
52. 2008 Nuclear to non-nuclear Pmel17/gp100 expression (HMB45 staining) as a discriminator between benign and malignant melanocytic lesions Mod Pathol 2008 Sep;21(9):1121-9.
53. 2007 Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma. Cancer Res. 67:1502-12
54. 2007 The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization J Transl Med 5:6
55. 2007 Bimodal population or pathologist artifact? J Clin Oncol (letter) ;25(17):2487-8.
56. 2007 Melanophages reside in hypermelanotic, aberrantly glycosylated tumor areas and predict improved outcome in primary cutaneous malignant melanoma J Cutan Pathol 34, 679-686
57. 2007 Quantitative justification of the change from 10% to 30% for human epidermal growth factor receptor 2 scoring in the american society of clinical oncology/college of american pathologists guidelines: tumor heterogeneity in breast cancer and its implications for tissue microarray based assessment of outcome . J Clin Oncol 25, 5418-5425
58. 2007 Utility of multispectral imaging for nuclear classification of routine clinical histopathology imagery BMC cell biology Jul 10;8 Suppl 1:S8
59. 2007 Quantitative measurement of epidermal growth factor receptor is a negative predictive factor for tamoxifen response in hormone receptor positive premenopausal breast cancer J Clin Oncol. Jul 20;25(21):3007-14
60. 2007 Variation in breast cancer hormone receptor and HER2 levels by etiologic factors: A population-based analysis Int J Cancer. Sep 1;121(5):1079-85
61. 2007 Quantitative analysis of breast cancer tissue microarrays shows high cox-2 expression is associated with poor outcome Cancer Investigation 25, 19-26
62. 2007 Phosphorylation of Akt (Ser473) predicts poor clinical outcome in oropharyngeal squamous cell cancer Cancer Epidemiol Biomarkers Prev 16, 553-558
63. 2007 Differences in risk factors for breast cancer molecular subtypes in a population-based study Cancer Epidemiol Biomarkers Prev. 16, 439-443
64. 2007 High HSP90 expression is associated with decreased survival in breast cancer Cancer Res 67: 2932-2937.
65. 2007 Quantitative analysis of estrogen receptor heterogeneity in breast cancer Lab Invest. 2007 Jul;87(7):662-9
66. 2007 Definition of a direct extracellular interaction between Met and E-cadherin Cell Biol Int. 2007 Apr;31(4):366-73
67. 2007 Antibody validation by quantitative analysis of protein expression using expression of Met in breast cancer as a model Lab Invest 87(3):251-60.
68. 2006 Molecular classification identifies a subset of human papillomavirus--associated oropharyngeal cancers with favorable prognosis J Clin Oncol 24, 736-747
69. 2006 Immunohistochemistry and quantitative analysis of protein expression Arch Pathol Lab Med 130, 1026-1030
70. 2006 What's in a name? Arch Pathol Lab Med 130, 934-935.
71. 2006 What brown cannot do for you (commentary) Nat Biotechnol 24, 914-916.
72. 2006 Classification of breast cancer using genetic algorithms and tissue microarrays Clin Cancer Res 12, 6459-6468
73. 2006 AQUA and FISH analysis of HER-2/neu expression and amplification in a small cell lung carcinoma tissue microarray Histopathology 49, 161-9
74. 2006 Automated quantitative analysis of DCC tumor suppressor protein in ovarian cancer tissue microarray shows association with {beta}-catenin levels and outcome in patients with epithelial ovarian cancer Ann Oncol
75. 2006 Construction and Validation of Tissue Microarrays of Ductal Carcinoma In Situ and Terminal Duct Lobular Units Associated With Invasive Breast Carcinoma Diagn Mol Pathol. Sep;15(3):157-161
76. 2006 Met, the hepatocyte growth factor receptor, localizes to the nucleus in cells at low density Cancer Res 66, 7976-7982.
77. 2006 Cruella: developing a scalable tissue microarray data management system Arch Pathol Lab Med 130, 817-822
78. 2006 Evaluation of the prognostic value of cellular inhibitor of apoptosis protein in epithelial ovarian cancer using automated quantitative protein analysis Cancer Epidemiol Biomarkers Prev 15, 1179-1183
79. 2006 Expression of tumor necrosis factor--related apoptosis-inducing ligand receptors 1 and 2 in melanoma. Clin Cancer Res 12, 3856-3863
80. 2006 Direct Interaction of the C-Terminal Domain of alpha-Catenin and F-Actin is Necessary for Stabilized Cell-Cell Adhesion Cell Commun Adhes 13, 151-170.
81. 2006 Quantitative In situ Analysis of {beta}-Catenin Expression in Breast Cancer Shows Decreased Expression Is Associated with Poor Outcome Cancer Res 66, 5487-5494
82. 2006 Vascular endothelial growth factor, FLT-1, and FLK-1 analysis in a pancreatic cancer tissue microarray. Cancer 106, 1677-1684
83. 2006 Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma Oncogene
84. 2006 The value of onsite adequacy assessment of thyroid fine-needle aspirations is a function of operator experience. Cancer 108, 110-113
85. 2006 Hypercalcemia of malignancy due to ectopic transactivation of the parathyroid hormone gene. J Clin Endocrinol Metab 91, 580-583
86. 2005 Effect of epidermal growth factor receptor expression level on survival in patients with epithelial ovarian cancer Clin Cancer Res. 11:8637-43
87. 2005 "Lineage Addiction" in Human Cancer: Lessons from Integrated Genomics Cold Spring Harb Symp Quant Biol.70:1-10.
88. 2005 Quantitative in situ proteomics: molecular pathology comes of age with automated tissue microarray analysis Personalized Medicine 2(4):291-300.
89. 2005 Tissue microarrays without cores Nat Methods 2(7):492-3
90. 2005 Automated quantitative analysis (AQUA) of in situ protein expression, antibody concentration, and prognosis J Natl Cancer Inst. 97:1808-15
91. 2005 Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease Cancer Res. 65:10938-45
92. 2005 Subcellular localization and protein levels of cyclin-dependent kinase inhibitor p27 independently predict for survival in epithelial ovarian cancer Clin Cancer Res. 11:8384-90
93. 2005 Automated quantitative analysis of activator protein-2alpha subcellular expression in melanoma tissue microarrays correlates with survival prediction Cancer Res. 65:11185-92
94. 2005 Detection of malignancy in cytology specimens using spectral-spatial analysis Lab Invest. 85:1555-64.
95. 2005 Coexpression of {beta}1,6-N-Acetylglucosaminyltransferase V Glycoprotein Substrates Defines Aggressive Breast Cancers with Poor Outcome Cancer Epidemiol Biomarkers Prev. Nov;14(11):2517-23
96. 2005 Patterns of reduced nipple aspirate fluid production and ductal lavage cellularity in women at high risk for breast cancer Breast Cancer Res. Oct 24;7(6):R1017-R1022
97. 2005 Immunohistochemical biomarkers in patients with early-onset breast carcinoma by tissue microarray Cancer J. 11(5):404-11
98. 2005 Evaluating the expression and prognostic value of TRAIL-R1 and TRAIL-R2 in breast cancer. Clin Cancer Res, 11:5188-5194
99. 2005 Quantitative determination of nuclear and cytoplasmic epidermal growth factor receptor expression in oropharyngeal squamous cell cancer by using automated quantitative analysis Clin Cancer Res 11:5856-5862
100. 2005 Translational crossroads for biomarkers Clin Cancer Res 11:6103-6108.
101. 2005 Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma Nature 436 (7047) 117-122
102. 2005 Using a xenograft model of human breast cancer metastasis to find genes associated with clinically aggressive disease. Cancer Res 65: 5578-5587
103. 2005 Automated quantitative analysis of E-cadherin expression in lymph node metastases is predictive of survival in invasive ductal breast cancer Clin Cancer Res. Jun 1;11(11):4083-9
104. 2005 {beta}1,6-Branched oligosaccharides are increased in lymph node metastases and predict poor outcome in breast carcinoma. Clin Cancer Res 11, 2969-2973.
105. 2005 Functional correlates of mutation of the Asp32 and Gly34 residues of beta-catenin Oncogene 24, 2667-2676
106. 2005 Beta-Catenin functions mainly as an adhesion molecule in patients with squamous cell cancer of the head and neck Clin Cancer Res 11, 2471-2477
107. 2005 Cyclin D1 is a valuable prognostic marker in oropharyngeal squamous cell carcinoma Clin Cancer Res. 11:1160-6
108. 2005 Upstaging based solely on positive peritoneal washing does not affect outcome in endometrial cancer Modern Pathology. May;18(5):673-80
109. 2004 Expression Profiling Reveals Novel Pathways in the Transformation of Melanocytes to Melanomas . Cancer Research 64: 5270-5282
110. 2004 Diagnostic Classification of Urothelial Cells in Urine Cytology Specimens Using Exclusively Spectral Information Cancer 102(3):186-91
111. 2004 Molecular markers for prognosis after isolated postmastectomy chest wall recurrence Cancer, 100: 252-263
112. 2004 New Technologies and the Future of Cytopathology ASC Bulletin 41(6):104-107.
113. 2004 Book Review of “Prognostic and Predictive Factors in Breast Cancer” by R. Walker New England Journal of Medicine 350(2) 200-201
114. 2004 Macrophage colony-stimulating factor-1 receptor expression is associated with poor outcome in breast cancer by large cohort tissue microarray analysis Clin. Cancer Research 10(1): 173-7.
115. 2004 Quantitative Determination of Expression of the Prostate Cancer Protein Alpha-Methylacyl-CoA Racemase (AMACR) using AQUA: A novel paradigm for automated and continuous biomarker measurements Am. J. Pathol. 164(3): 831-840
116. 2004 Technology Insight: identification of biomarkers with tissue microarray technology Nature Clinical Practice Oncology 1(2) 104-111
117. 2004 A Novel Tyramide-Based Tyrosinase Assay for the Detection of Melanoma Cells in Cytological Preparations. Diag. Cytopathol. 31(1):33-7.
118. 2004 Tissue Microarrays in Cancer Principals and Practice of Oncology”, 7th edition, (DiVita, Rosenberg and Hellman eds) Chapter 1, section 4 pp 26-33
119. 2004 Her2/neu is not a commonly expressed therapeutic target in melanoma – a large cohort tissue microarray study Melanoma Research 14(3):207-10
120. 2004 Beta-catenin and p53 Analyses on a Breast Cancer Tissue Microarray Cancer 100: 2084-2092.
121. 2004 The Histologic Subtype of Ovarian Tumors Affects the Detection Rate by Pelvic Washings Cancer 102(3):186-91
122. 2004 AlphaB-crystallin as a marker of metastatic potential in breast cance Cancer 100(12):2543-8.
123. 2004 Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections Ann Thorac Surg. 78(6):2106- 10; discussion 2110-1.
124. 2004 Automated Quantitative Analysis (AQUA) of Tissue Microarrays Reveals an Association between High Bcl-2 Expression and Improved Outcome in Melanoma Cancer Res. 64(23):8773-7
125. 2004 Automated Quantitative Analysis (AQUA) of HDM2 Expression in Malignant Melanoma Shows Association with Early Stage Disease and Improved Outcome Cancer Res 64(23):8767-72.
126. 2004 Prognostic Significance of p16 Protein Levels in Oropharyngeal Squamous Cell Cancer Clin Cancer Res 10:5684-5691
127. 2004 Long term preservation of antigenicity on tissue microarrays. Lab Invest 84(8):1071-8
128. 2003 Tissue Microarray-Based Analysis Shows Phospho-beta-catenin Expression in Malignant Melanoma is Associated with Poor Outcome. Int J Cancer. Feb 20;103(5):652-6
129. 2003 JAKs and STATs as Biomarkers of Disease Signal Transducers and Activators of Transcription (STATs) Activation and Biology”. (Seghal, Levy and Hirano eds.) Kluwer, Amsterdam. pp 697-719
130. 2003 Loss Of Smad Signaling Is Associated With Poor Outcome In Human Colorectal Cancer – A Tissue Microarray Analysis. Cancer J., Jul-Aug;9(4):302-12.
131. 2003 Functional correlates of mutations in beta-catenin Exon 3 phosphorylation sites J Biol Chem. Aug 22;278(34):31781-9
132. 2003 BRCA Status, Molecular Markers, and Clinical Variables in Early, Conservatively Managed Breast Cancer Breast J. 9:167-74
133. 2003 Quantitative Analysis of Breast Cancer Tissue Microarrays Shows That Both High and Normal Levels of HER2 Expression Are Associated with Poor Outcome Cancer Research 63:1445-1448
134. 2003 Tissue Microarray based studies of node-negative breast cancer patients show Met expression associated with worse outcome but not correlated with EGF family receptors. Cancer 97(8):1841-1848.
135. 2003 Tissue Microarray Analysis of Hepatocyte Growth Factor/Met Pathway Components Reveals a Role for Met, Matriptase, and Hepatocyte Growth Factor Activator Inhibitor 1 in the Progression of Node-negative Breast Cancer Cancer Research 63:1101-1105
136. 2003 Tissue Microarray Analysis of Stat3 and Phospho-Stat3 (Tyr705) in Node-Negative Breast Cancer Shows Nuclear Localization is Associated with a Better Prognosis. Clin Cancer Res. 9:594-600.
137. 2003 Detection of Chromosomal Instability in Paired Breast Surgery and Ductal Lavage Specimens by Interphase FISH Clin Cancer Res ;9 1509-1516
138. 2003 Investigation of Automated Feature Extraction Techniques for Applications in Cancer Detection from Multispectral Histopathology Images Proc. of SPIE, 5032: 557-566
139. 2003 Subcellular Localization of Activating Transcription Factor 2 (ATF2) in Melanoma Specimens Predicts Patient Survival Cancer Research 63:8103-8107
140. 2003 Frequent Alterations of Smad Signaling in Human Head and Neck Squamous Cell Carcinomas: a Tissue Microarray Analysis Oncology Research 14:61-73
141. 2002 Subjective Differences In Outcome Are Seen as a Function Of the Immunohistochemical Method Used on a Colorectal Cancer Tissue Microarray Clinical Colorectal Cancer 1(4) 237-242
142. 2002 Immunocytochemical Analysis of Breast Cells Obtained by Ductal Lavage. Cancer Cytopath 96:244-249
143. 2002 Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study Cancer Res 62:497-505.
144. 2002 Quantitative Examination Of The Mechano-Physical Cancer Cell Enrichment In Fine Needle Aspiration Specimens. Cancer Cytopath 96(5):275-279
145. 2002 Use of Magnetic Enrichment for Detection of Carcinoma Cells in Fluid Specimens Cancer 94(1):205-211
146. 2002 Tissue Microarray Technology: A New Standard for Molecular Evaluation of Tissue? Principals and Practice of Oncology Updates 16(4):1-11
147. 2002 Automated subcellular localization and quantification of protein expression in tissue microarrays. Nature Medicine 8(11):1323-7
148. 2002 p53 mutations as tumor markers in fine needle aspirates of palpable breast masses Acta Cytol 46(5):841-7
149. 2001 Amplification of Tissue by Construction of Tissue Microarrays Exp and Molec. Pathol, 70:255-264
150. 2001 Impact of Microarray Technologies on Cytopathology Acta Cytologica 45(2):111-114
151. 2001 Tissue Microarray: A New Technology for Amplification of Tissue Resources Cancer Journal 7:24-31
152. 2001 Tissue Microarray Analysis of b-catenin in Colorectal Cancer Shows Nuclear Phospho-b-catenin is Associated with a Better Prognosis Clinical Cancer Research 7:4013-4020
153. 2001 Novel Loss-Of-Function Mutations of Transforming Growth Factor-Beta Type I Receptor Gene in Fine Needle Aspiration of Head and Neck Cancer Metastasis Int J Cancer 93:653-661
154. 2001 Alpha-Catenin Binds Directly to Spectrin and Facilitates Spectrin-Membrane Assembly in vivo. J. Biol.Chem. 276:4175-4181
155. 2001 Truncated DCC Reduces N-Cadherin/Catenin Expression and Calcium Dependent Cell Adhesion in Neuroblastoma Cells. Lab Invest 81(2)201-210
156. 2001 Beta-Catenin Dysregulation In Thyroid Neoplasms: Downregulation, Aberrant Nuclear Expression And Ctnnb1 Exon 3 Mutations Are Markers For Aggressive Tumor Phenotypes And Poor Prognosis Amer. J Pathol. 158(3):987-996
157. 2001 The Diagnosis of “ASCUS” in Women Over Age 50 is Less Likely to be Associated with Dysplasia Diagnostic Cytopathology 24(2)132-136
158. 2001 Parathyroid related protein maintains mammary epithelial fate and triggers nipple skin differentiation during embryonic breast development Development 128:513-525
159. 2000 The Utility of Ki-ras Mutation Analysis in the Cytologic diagnosis of Pancreatobiliary Neoplasms Cancer Journal 6(5)299-305
160. 2000 The new molecular biology section of Acta Cytologica: An introduction Acta Cytologica 44(5):701-702
161. 2000 Molecular Biology in Cytopathology: Current Applications and Future Direction Cancer Cytopathology 90(1):1-9
162. 2000 High numbers of tumor-free axillary lymph nodes in node-negative breast carcinoma are associated with poor outcome Cancer 88:108-13
163. 2000 E-cadherin expression is a sensitive and specific method for detection of carcinoma cells in fluid specimens. Diagn Cytopathol 22:263-267
164. 2000 Validation of Tissue Microarray Technology in Breast cancer Lab. Invest. 80(12)1943-1949
165. 1999 Frequent Mutation and Nuclear Localization of beta-catenin in Anaplastic Thyroid Carcinoma. Cancer Research 8:1811-1815
166. 1999 Met expression is associated with poor outcome in node-negative breast cancer Cancer 86:259-265
167. 1999 PECAM-1 (CD31) functions as a reservoir for, and a modulator of tyrosine phosphorylated beta-catenin. J. Cell Science 112(18):3005-3014
168. 1999 Controversies at the Cytoplasmic Face of the Cadherin-based Adhesion Complex Current Opinions In Cell Biology 11:567-572
169. 1999 alpha- and beta-catenin mutations, but not E-cadherin alterations, underlie Tcf/Lef transcriptional deregulation in gastric and pancreatic cancer Cell Growth & Diff, 10(6):369-376
170. 1999 Frequent Nuclear/Cytoplasmic Localization of beta-catenin Without Exon 3 Mutations in Malignant Melanoma Amer J Pathol. 154(2):325-329
171. 1998 The expression of p120ctn protein in breast cancer is independent a-catenin and b-catenin and E‑cadherin Amer. J. Pathol. 152(1): 75-82
172. 1998 Expression of the SF/HGF receptor c-met in breast cancer is a strong independent predictor of decreased survival. Cancer 82(8):1513-1520
173. 1998 Dynamic interaction of PTPµ with multiple cadherins in vivo J. Cell Biol. 141(1):287-296
174. 1998 PCR-Based Detection of Clonality as an Objective Diagnostic Tool for Breast Fine Needle Aspiration Cancer Cytopath 84(4):262-267
175. 1998 Loss of p120ctn in Human Colorectal Cancer Predicts Metastasis and Poor Survival Cancer Letters 132:192-201
176. 1998 A Mutation In a-Catenin Disrupts Adhesion In Clone A Cells Without Perturbing Its Actin And a-Catenin Binding Activity Cell Adhesion and Commun. 5:283-296
177. 1997 Estimation of Cost Savings Achieved as a result of Fine Needle Aspiration Instead of Surgical Biopsy. Cancer Cytopath 81:51-56
178. 1997 Vinculin is associated with the E-cadherin adhesion complex J. Biol. Chem. 272(51): 32448-32453
179. 1997 Alpha-Catenin Can Form Asymmetric Homodimeric Complexes and/or Heterodimeric Complexes With b-catenin J. Biol. Chem. 272(43):27301-27306
180. 1997 Atypical squamous cells of undetermined significance: correlative histologic and follow-up studies from an academic medical center Diagn Cytopathol 16:1-7
181. 1997 The cell adhesion molecule, E‑cadherin, distinguishes mesothelial cells from carcinoma in fluids Cancer Cytopath 81(5):293-298
182. 1997 Localization and Quantitation of Expression of the Cell Motility related protein Thymosin b15 in Human Breast Tissue Modern Pathology 10(11):1106-1112
183. 1997 Loss of E‑cadherin expression in breast cancer results from transcriptional defects Cell Growth and Diff. 8:773-778
184. 1997 Cytology Follow-up of the “ ASCUS” Diagnosis Predicts a Lower Level of Dysplasia than Biopsy Diag. Cytopathol. 17:14-19
185. 1996 Atypical Reparative Change on Cervical/Vaginal Smears May Be Associated with Dysplasia Diag Cytopathol. 14(4):374-379
186. 1996 Expression of a candidate cadherin in T lymphocytes PNAS 93:6567-6571
187. 1996 Of Membrane Stability and Mosaics: The Spectrin Cytoskeleton “Handbook of Physiology” ( J. Hoffman and J. Jamieson eds) Oxford Press
188. 1995 The Receptor Protein Tyrosine Phosphatease PTPµ Associates with Cadherins and Catenins In Vivo J. Cell Biol. 130(4): 977-986
189. 1995 Auto-Antibodies specific for Villin and other Brush Border proteins are found in Patients with Colon Cancer and other Colitides Dig.Dis. and Sci. 40(2):389-395
190. 1995 Loss or decrease in expression of E‑cadherin and a- and b-catenins in human breast carcinoma-derived cell lines. Oncogene 11:1319-1326
191. 1995 Alpha1(E) catenin is a novel actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. PNAS 92:8813-8817
192. 1995 Reduced a-catenin and E-cadherin expression in Breast Cancer Lab Invest 72(5): 590-603
193. 1994 Molecular Cloning of Human E-cadherin Suggests a Novel Subdivision of the Cadherin Superfamily Biochem Biophy Res Commun 200: 1754-1761
194. 1994 Molecular Cloning Reveals Alternative Splice Forms of Human a(E)-Catenin Biochem Biophy Res Commun 203: 1691-1699
195. 1994 Heterophilic adhesion between epithelial cells and T Lymphocytes mediated by E-cadherin Nature 372: 190-192
196. 1993 Nuclear Actin Binding Protein (NAB) “Guidebook to the Cytoskeletal and Motor Proteins (T. Kreis, and R. Vale, eds) Oxford University Press, New York
197. 1991 Analysis of cDNA clones for Acanthamoeba Profilin‑I and Profilin-II shows End to End Homology with Vertibrate Profilins and a Small Family of Profilin Genes Cell Motility and the Cytoskeleton 20: 169-177
198. 1991 Prolonged "Locked-In Syndrome” Following a Viral Illness: Clinical and Pathological Findings. Neurology 41: 498-500
199. 1990 Fusion Proteins Purified from E. coli Lysates Identify 2 Distant Regions of the Acanthamoeba Myosin‑II tail Important for Minifilament Assembly J. Cell Biol. 111: 2417-2426
200. 1990 Identification of Functional Regions on the Tail of Acanthamoeba Myosin-II by High Resolution Mapping of Monoclonal Antibody Binding Sites on Recombinant Fusion Protiens J. Cell Biol. 111: 2405-2416
201. 1989 Purification and Characterization of an Acanthamoeba Nuclear Actin -Binding Protein J. Cell Biol. 109: 585-591
202. 1989 Structure -Function Studies of the Actin Filament System of Acanthamoeba Springer Series in Biophysics" (U. Aebi and J. Engel, eds.), Vol. 3, "Cytoskeletal and Extracellular Proteins", 2nd Intern. Symp. European Biophys. Soc., Gwatt, Switzerland, pp 271-279, London
203. 1989 New Plasmid Vectors for High Level Synthesis of Eukaryotic Fusion Proteins in E. coli Gene 75: 323-327
204. 1989 Location of the Head -Tail Junction of Myosin J.Cell Biol. 108: 1783-1789
205. 1989 Obesity and Heredity in the Etiology of Non-Insulin-Dependent Diabetes Mellitus in 32,662 Adult White Women. Am. J. Epidemiol. 130: 112-121
206. 1988 Resolution of Acanthamoeba castellanii chromosomes by pulsed field gel electrophoresis and construction of the initial linkage map Chromosoma 97: 219-223.
207. 1986 Characterization of Alpha-actinin from Acanthamoeba Cell Motility and the Cytoskeleton 6: 649-661
208. 1984 Structural analysis of the murine IgG3 constant region gene EMBO J 3(9):2041-6
209. 1980 Construction of Coli-phage Lambda Charon Vectors with BamH1 Cloning Sites. Gene 12: 301-309


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