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Peer Reviewed Papers, Books, Chapters

Year Title Citation Authors
1. 2011 Critical role of astroglial ApoE and Liver X Receptor expression for microglial A phagocytosis” J. Neuroscience, in press 2011
2. 2011 The role of the estrogen/estrogen-receptor-beta axis in the genomic response to pressure overload-induced hypertrophy Physiol. Genomics, in press 2011.
3. 2011 Estrogen receptor b signals left ventricular hypertrophy sex differences in normotensive deoxycorticosterone acetate-salt mice Hypertension, 3, 648-654
4. 2011 Both LXR isoforms control energy expenditure by regulating BAT activity Proc. Natl. Acad. Sci. USA, 108, 403-408
5. 2011 Lactobacillus Paracasei F19 decreases fat storage by regulating fasting induced adipose factor (FIAF). PLoS ONE, 2010 Sep 30;5(9). Pii: e13087
6. 2011 Estrogen receptors: Diseases and estrogen receptor-subtype targeted therapies Clin Pharmacol Ther, 89, 44-55
7. 2011 Quantitative proteomics and transcrptomics addressing the estrogen receptor subtypemediated effects in T47D breast cancer cells exposed to the phytoestrogen genistein Mol Cell Proteomics, 10.1074/mcp.M110.002170-1
8. 2010 Estrogen signaling via estrogen receptor b. J. Biol. Chem., 285, 39575-39579
9. 2010 Estrogen-dependent gallbladder carcinogenesis in LXRb-/- female mice Proc. Natl. Acad. Sci. USA, 14763-14768
10. 2010 Estrogen receptor beta decreases survival of p53-defective cancer cells after DNA damage by impairing G2/M checkpoint signaling. Breast Cancer Res.Treat
11. 2010 Perspective: Estrogen receptors in colorectal cancer: Goalkeepers, strikers or bystanders Cancer Prev. Res. 8, 897-899
12. 2010 Liver X receptor b and thyroid hormone receptor a in brain cortical layering . Proc. Natl. Acad. Sci. USA, , 107, 12305-12310
13. 2010 ERb: recent understanding of estrogen signaling Trends Endocrinol Metab., 21, 545-552
14. 2010 SOX9 mediates the retinoic acid-induced HES-1 gene expression in human breast cancer cells Breast Cancer Res. Treat., 120, 317-326
15. 2010 Genome-wide mapping of estrogen receptor b binding regions reveals extensive cross talk with AP-1 Cancer Res. 70, 5174-5183
16. 2010 Nuclear receptor in analytics – a fruitful joint venture or a wasteful futility? Trends Analyt. Chem., 29, 297-305
17. 2010 Characterization of neuropathological and biochemical changes during the disease progression in liver X receptor b -/- mice, a model of adult neuron disease . J. Neuropathol. Exp. Neurol., 69, 593-605
18. 2010 Proteomic analysis of the estrogen receptor alpha receptosome Mol. Cell Proteomics 9.7, 1411-1422
19. 2010 Gonadotropin-positive pituitary tumors accompanied by ovarian tumors in aging female ERb-/- mice. Proc. Natl. Acad. Sci. USA, 107, 6453-6458
20. 2010 Levels of 17a-estradiol receptors expressed in embryonic and adult zebrafish following in vivo treatment of natural or synthetic ligands PLoS ONE 5(3): e9678.doi:10.1371/journal. Pone.0009678
21. 2010 ADD1/SREBP1c activates the PGC1-a promoter in brown adipocytes Biochim. Biophys. Acta, 1801, 421 429
22. 2010 GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRb in the hepatic acute phase response. Genes Dev., 24, 381-395
23. 2010 RBCK1 drives breast cancer cell proliferation by promoting transcription of estrogen receptor a and cyclin B1 Cancer Res., 70, 1265-1274
24. 2010 Tumor-mediated liver X receptor-a activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses Nature Medicine, 16, 98-106
25. 2010 The human ADFP gene is a direct Liver-X-Receptor (LXR) target gene and differentially regulated by synthetic LXR ligands Mol. Pharmacol. 77, 79—86
26. 2009 Rapid regulation of KATP channel activity by 17b-estradiol in pancreatic b-cells involves the estrogen receptor b and the atrial natriuretic peptide receptor Mol. Endocrinol., 23, 1973-1982
27. 2009 Hes-6, an inhibitor of Hes-1, is regulated by 17b-estradiol and promotes breast cancer cell proliferation Breast Cancer Res., 11:R79, 1-9
28. 2009 Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARa-dependent stearoyl-coenzyme a desaturase PLosOne, 4, 1-14
29. 2009 bexarotene modulates triglyceride but not cholesterol metabolism via gene-specific permissivity of the RXR/LXR heterodimer in the liver Arterioscler. Thromb. Vasc. Biol., 29, 1488-1495
30. 2009 Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells Cell Stem Cell, 5, 409-419
31. 2009 The human thioredoxin reductase-1 splice variant TXNRD1_v3 is an atypical inducer of cytoplasmic filaments and cell membrane filopodia. Biochim Biophys. Acta, 1793, 1588-1596
32. 2009 Disruption of estrogen receptor signaling enhances intestinal neoplasia in ApcMin/+ mice Carcinogenesis, 30, 1581-1590
33. 2009 Genetic mapping of Mom5, a novel modifier of ApcMin-induced intestinal tumorigenesis Carcinogenesis, 30, 1591-1596
34. 2009 : Tumor repressive functions of estrogen receptor b in SW480 colon cancer cells Cancer Res., 15, 6100-6106
35. 2009 Functional interaction of DYX1C1 with estrogen receptors suggest involvement of hormonal pathways in dyslexia Human Molecular Genetics, 18, 2802- 2812
36. 2009 Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice J. Clin. Invest., 119, 1626-1637
37. 2009 GPS2 is required for cholesterol efflux by triggering histone demethylation, LXR recruitment, and coregulator assembly at the ABCG1 locus Mol. Cell, 34, 510-518
38. 2009 Ablation of estrogen receptor a or b eliminates sex differences in mechanical pain threshold in normal and inflamed mice Pain, 143, 37-40
39. 2009 The oxysterol receptor LXR inhibits proliferation of human breast cancer cells Carcinogenesis, 30, 575-579,
40. 2009 E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesis Mol. Cell Biol., 29, 2230-2242
41. 2009 A role for epithelial-mesenchymal transition in the etiology of benign prostatic hyperplasia Proc. Natl. Acad. Sci. USA, 106, 2859-2863
42. 2009 Hormonal regulation of prolactin cell development in the fetal pituitary gland of the mouse Endocrinology, 150, 1061-1068
43. 2009 Minireview: Liver X receptor b: Emerging roles in physiology and diseases Mol. Endocrinol., 23, 129-136
44. 2009 Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain Mol. Psychiatry, 14, 223-232
45. 2009 Stromal growth and epithelial cell proliferation in ventral prostates of liver X receptor knockout mice Proc. Natl. Acad. Sci. USA, 106, 558-563
46. 2008 Different roles of estrogen receptors α and β in the regulation of E-cadherin protein levels in a mouse mammary epithelial cell line Cancer Res. 68, 8695-8704
47. 2008 Activation of liver X receptors prevents statin-induced death of 3T3-L1 preadipocytes J. Biol. Chem, 283, 22723-22736
48. 2008 Estrogen receptor β selective ligand 5α-androstane-3β, 17β-diol stimulates spermatogonial deoxyribonucleic acid synthesis in rat seminiferous epithelium in vitro Endocrinol., 149, 2917-2922
49. 2008 RAP250 is a coactivator in the transforming growth factor β signaling pathway that interacts with Smad2 and Smad3 J. Biol. Chem., 283, 8995-9001
50. 2008 Pancreatic exocrine insufficiency in LXRβ-/- mice is associated with a reduction in aquaporin-1 expression Proc. Natl. Acad. Sci. USA, 105, 15052-15057
51. 2008 Expression of liver X receptor β is essential for formation of superficial cortical layers and migration of later-born neurons Proc. Natl. Acad. Sci. USA, 105, 13445-13450
52. 2008 PLoS Genetics, 4, 1-16 Metabolic actions of estrogen receptor beta (ERβ) are mediated by a negative cross-talk with PPARγ
53. 2008 Estrogen receptor β protects against acoustic trauma in mice J. Clin. Investigation, 118, 1563-1570
54. 2008 The genome landscape of ERα- and ERβ-binding DNA regions Proc. Natl. Acad. Sci. USA, 105, 2604-2609
55. 2008 A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells Oncogene, 27, 1019-1032
56. 2008 Liver X receptor b (LXR b): A link between b-sitosterol and amyotrophic lateral sclerosis-Parkinson’s dementia Proc. Natl. Acad. Sci. USA, 105, 2094-2099
57. 2008 Genome-wide identification of estrogen receptor a-binding sites in mouse liver Mol. Endocrinol., 22, 10-22
58. 2007 Estrogen receptors: How do they signal and what are their targets Physiol. Rev., 87, 905-931
59. 2007 Wrestling rules in transrepression: As easy as SUMO-1, -2, -3 Mol. Cell, 25, 178-180
60. 2007 Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis Proc. Natl. Acad. Sci. USA, 104, 15665-15670
61. 2007 Inhibitory effects of estrogen receptor beta on specific hormone-responsive gene expression and association with disease outcome in primary breast cancer Breast Cancer Res., 9:R25, 1-11
62. 2007 Estrogen receptor b is essential for sprouting of nociceptive primary afferents and for morphogenesis and maintenance of the dorsal horn interneurons Proc. Natl. Acad. Sci. USA, 104, 13696-13701
63. 2007 Estrogen receptor b deficient female mice develop a bladder phenotype resembling human interstitial cystitis Proc. Natl. Acad. Sci. USA, 104, 9806-9809
64. 2007 : Estrogen receptor b2 negatively regulates the transactivation of estrogen receptor a in human breast cancer cells Cancer Res., 67, 3955-3962
65. 2007 Ovarian wedge resection restores fertility in estrogen receptor b knockout (ERb-/-) mice Proc. Natl. Acad. Sci. USA, 104, 600-605
66. 2006 The hair follicle as an estrogen target and source Endocrine Rev., 6, 677-706
67. 2006 Estrogen receptors: new players in diabetes mellitus Trends Mol. Med., 12, 425-431
68. 2006 Estrogen receptor b expression in the embryonic brain regulates development of calretinin-immunoreactive GABAergic interneurons Proc. Natl. Acad. Sci. USA., 103, 19338-19343
69. 2006 Estrogen receptor b inhibits angiogenesis and growth of T47D breast cancer xenografts Cancer Res., 23, 11207-11213
70. 2006 Role of estrogen receptor b in uterine stroma and epithelium: Insights from estrogen receptor b mice Proc. Natl. Acad. Sci. USA., 103, 18350-18355
71. 2006 : Cholesterol-sensing receptors, liver X receptor and , have novel and distinct roles in osteoclast differentiation and activation. J. Bone Min Res., 21, 1276-1287
72. 2006 Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: A possible mechanism is through direct regulation of signal transducer and activator of transcription 3 Mol. Endocrinol., 6, 1287-1299
73. 2006 Lung dysfunction causes systemic hypoxia in estrogen receptor b knockout (ERb-/-) mice Proc. Natl. Acad. Sci. USA., 103, 7165-7169
74. 2006 Estrogen receptor b polymorphism is associated with prostate cancer risk. Clin. Cancer Res., 12, 1936-1941
75. 2006 Estrogen receptor (ER) b modulates ERa-mediated transcriptional activation by altering the recruitment of c-Fos and c-Jun to estrogen responsive promoters Mol. Endo., 20, 534-543
76. 2006 Role of estrogen receptor b in colonic epithelium Proc. Natl. Acad. Sci. USA., 103, 2959-2964
77. 2006 Muscle GLUT4 regulation by estrogen receptors ER and ER Proc. Natl. Acad. Sci. USA., 103, 1605-1608
78. 2005 Transcriptional corepression by SHP: molecular mechanisms and physiological consequences Trends Endocrin. Met, 16, 478-488
79. 2005 Steroids and the scientis . Mol. Endocrinol., 19, 1412-1417
80. 2005 Reflections on the discovery and significance of estrogen receptor b. Endocrine Rev., 29, 465-478
81. 2005 EID3 is a novel EID family member and an inhibitor of CBP-dependent co-activation Nucleic Acids Res., 33, 3561-3569
82. 2005 Liver X receptors a and b regulate renin expression in vivo, J. Clin. Invest. 115, 1913-1922
83. 2005 The liver X receptor-b is essential for maintaining cholesterol homeostasis in the testis Endocrinology, 146, 2519-2530
84. 2005 Increased estrogen receptor bcx expression during mammary carcinogenesis Clin. Cancer Res., 11, 3170-3174
85. 2005 A previously uncharacterized role for estrogen receptor b: Defeminization of male brain and behavior Proc. Natl. Acad. Sci. USA., 102, 4608-4612
86. 2005 Inactivation of liver X receptor b leads to adult-onset motor neuron degeneration in male mice Proc. Natl. Acad. Sci. USA., 102, 3857-3862
87. 2005 Early onset of puberty and ovarian failure in CYP7B1 knockout mice Proc. Natl. Acad. Sci. USA., 102, 2814-2819
88. 2005 Estrogen receptor a and imprinting of the neonatal mouse ventral prostate by estrogen Proc. Natl. Acad. Sci. USA., 102, 1484-1489
89. 2004 Principles for modulation of the nuclear receptor superfamily Nature Reviews Drug Discovery, 3, 950-964
90. 2004 Putative metabolic effects of the liver X receptor (LXR) Diabetes, 53, S36-S42
91. 2004 Estrogen receptor beta in prostate cancer N. Engl. J. Med., 351, 2773-2774
92. 2004 HES-1 inhibits 17b-estradiol and heregulin-b1-mediated upregulation of E2F-1 Oncogene, 23, 8826-8833,
93. 2004 Characterization of the ERb -/- mouse heart Proc. Natl. Acad. Sci. USA., 101, 14234-14239
94. 2004 Estrogen receptor b (ERb) level but not its ERbcx variant helps to predict tamoxifen resistance in breast cancer Clin. Cancer Res., 10, 5769-5776
95. 2004 Aromatase-deficient mice spontaneously develop a lymphoproliferative autoimmune disease resembling Sjögren’s syndrome . Proc. Natl. Acad. Sci. USA., 101, 12628-12633
96. 2004 Estrogen receptor b regulates epithelial cellular differentiation in the mouse ventral prostate Proc. Natl. Acad. Sci. USA., 101, 9375-9380
97. 2004 The expression of ERbcx in human breast cancer and the relationship to endocrine therapy and survival Clin. Cancer Res., 10, 2421-2428
98. 2004 Identification of tamoxifen-induced coregulator interaction surfaces within the ligand-binding domain of estrogen receptors Mol. Cell Biol., 24, 3445-3459
99. 2004 Estrogen receptors ERa and ERb in proliferation in the rodent mammary gland Proc. Natl. Acad. Sci. USA, 101, 3739-3746
100. 2004 Autoimmune glomerulonephritis with spontaneous formation of splenic germinal centers in mice lacking the estrogen receptor alpha gene Proc. Natl. Acad. Sci. USA, 101, 1720-1724
101. 2004 Estrogen receptor b inhibits 17b-estradiol-stimulated proliferation of the breast cancer cell line T47D Proc. Natl. Acad. Sci. USA, 101, 1566-1571
102. 2004 Association of estrogen receptor b gene polymorphisms with bulimic disease in women Mol. Psychiatry, 9, 28-34
103. 2003 What pharmacologists can learn from recent advances in estrogen signaling Trends Pharmacol. Sci
104. 2003 An endocrine pathway in the prostate, ERb, AR, 5a-androstane-3b, 17b-diol, and CYP7B1, regulates prostate growth Proc.Natl.Acad.Sci. USA, 99, 13589-13594
105. 2003 Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor a J. Biol. Chem., 278, 48283-48291,
106. 2003 : Regulation of postnatal lung development and homeostasis by estrogen receptor b Mol. Cell. Biol., 23, 8542-8552
107. 2003 The three-dimensional structure of the liver X receptor b reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands J. Biol. Chem., 278, 38821-38828
108. 2003 : Disruption of the estrogen receptor beta gene in mice causes myeloproliferative disease resembling chronic myeloid leukemia with lymphoid blast crisis Proc. Natl. Acad. Sci. USA., 100, 6694-6699
109. 2003 Estrogen receptor (ER)- b reduces ERa-regulated gene transcription, supporting a “ying yang” relationship between ERa and ERb in mice . Endocrinol. 17, 203-208
110. 2003 Estrogen receptor (ER) b knockout mice reveal a role for ERb in migration of corticol neurons in the developing brain Proc. Natl. Acad. Sci. USA, 100, 703-708
111. 2002 : Biological role of estrogen and estrogen receptors. Critical Rev. Biochem Critical Rev. Biochem Mol. Biol., 37, 1-28
112. 2002 Elucidation of estrogen receptor function in bone with the use of mouse models Trends Endocrin. Met., 13, 195-200
113. 2002 Involvement of estrogen receptor b in terminal differentiation of mammary gland epithelium. Proc. Natl. Acad. Sci. USA, 99, 15578-15583
114. 2002 Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue Mol. Pharmacol., 62, 1299-1305
115. 2002 An endocrine pathway in the prostate, ERb, AR, 5a-androstane-3b, 17b-diol, and CYP7B1, regulates prostate growth Proc.Natl.Acad.Sci. USA, 99, 13589-13594
116. 2002 Liver X receptors in the central nervous system: From lipid homeostasis to neuronal degeneration Proc.Natl.Acad.Sci. USA, 99, 13878-13883
117. 2002 Accumulation of foam cells in liver X receptor-deficient mice Circulation, 106, 1147-1153
118. 2002 Liver X receptor downregulates 11b-hydroxysteroid dehydrogenase type 1 expression and activity Diabetes, 51, 2426-2433
119. 2002 Estrogen actions in the brain Science STKE, 138, 2002. http://stke.sciencemag.org/cgi/content/full/sigtrans;2002/138/pe29
120. 2002 A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP EMBO reports, 5, 478-484
121. 2002 Liver X receptors as insuling-mediating factors in fatty acid and cholesterol biosynthesis J. Biol. Chem., 277, 10691-10697
122. 2002 Disruption of estrogen receptor b gene impairs spatial learning in female mice Proc.Natl.Acad.Sci. USA, 99, 3996-4001
123. 2002 Estrogen receptor beta in breast cancer Endocrine-Related Cancer, 9, 1-13
124. 2002 Abnormal vascular function and hypertension in mice deficient in estrogen receptor b Science, 295, 505-508
125. 2001 Comparing nuclear receptors in worms, flies and humans Trends Pharmacol. Sci., 22, 611-615
126. 2001 : Mechanism of estrogen action Physiol. Rev. 81, 1535-1565
127. 2001 Role of estrogen receptor beta in estrogen action Annu. Rev. Physiol., 63, 165-92
128. 2001 Female estrogen receptor b -/- mice are partially protected against age-related trabecular bone loss J. Bone and Mineral Res., 16
129. 2001 Frequent loss of estrogen receptor-b expression in prostate cance Cancer Res., 61, 5331-5335
130. 2001 Neurosteroid hydroxylase CYP7B vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation J. Biol. Chem., 276, 23937-23944
131. 2001 A role for estrogen receptor b in the regulation of growth of the ventral prostate Proc.Natl.Acad.Sci. USA, 98, 6330-6335
132. 2001 Structural insights into the mode of action of a pure antiestrogen Structure, 9, 145-153
133. 2001 Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRb-deficient mice J. Clin. Invest., 107, 565-573
134. 2001 Morphological abnormalities in the brains of estrogen receptor b knockout mice Proc.Natl.Acad.Sci. USA, 98, 2792-2796
135. 2000 Nematode genome sequence dramatically extends the nuclear receptor superfamily Trends Pharmacol. Sci., 21, 85-87
136. 2000 False negatives in oestrogen-receptor assay The Lancet, 356, 944
137. 2000 Abolition of male sexual behaviors in mice lacking estrogen receptors a and b (abERKO) Proc.Natl.Acad.Sci. USA, 97, 14737-14741
138. 2000 DAX-1 functions as an LXXLL-containing corepressor for activated estrogen receptors J. Biol. Chem., 275, 39855-39859
139. 2000 The Hairy and Enhancer of Split homologue-1 (HES-1) mediates the proliferative effect of 17b-estradiol on breast cancer cell lines Oncogene, 19, 5951-5953
140. 2000 Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic development Mechanisms of Development 97, 13-26
141. 2000 Estrogen receptor b acts as a dominant regulator of estrogen signaling Oncogene, 19, 4970-4978
142. 2000 Estrogen receptor (ER) b,a modulator of ERa in the uterus Proc.Natl.Acad.Sci. USA, 97, 5936-5941
143. 2000 : Estradiol induces differential neuronal phenotypes by activating estrogen receptor a or b Endocrinol., 141, 1839-1845
144. 2000 Cloning and characterization of RAP250, a novel nuclear receptor coactivator J. Biol. Chem. 275, 5308-5317
145. 2000 Estrogen receptors a and b in the rodent mammary gland Proc.Natl.Acad.Sci. USA, 97, 337-342
146. 1999 Steroid and nuclear receptors EMBO J., 18, 6201-6210
147. 1999 Seeking ligands for lonely orphan receptors Science, 284, 1285-1286,
148. 1999 Increased cortical bone mineral content but unchanged trabecular bone mineral density in female ERb -/- mice J. Clin. Invest., 104, 895-901
149. 1999 Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist EMBO J., 18, 4608-4618
150. 1999 Transcriptional targets shared by estrogen receptor-related receptors (ERRs) and estrogen receptor (ER) a, but not by ERb. EMBO J. 18, 4270-4279
151. 1999 : Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors a and b Proc. Natl. Acad. Sci. USA, 96, 7077-7082
152. 1999 Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors J. Biol. Chem., 274, 6667-6677
153. 1999 The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERa and ERb. J. Biol. Chem., 247, 345-353
154. 1998 Cross-talk between steroids and NF-kB: what language Trends Biochem. Sci., 233-235
155. 1998 Estrogen is a male and female hormone Science & Medicine, 5, 36-45
156. 1998 Therapeutic potential of selective estrogen receptor modulators Current Opinion in Chemical Biology, 2, 508-511
157. 1998 ERb: a novel estrogen receptor offers the potential for new drug development Trends Endocrin. Met., 9, 387-395
158. 1998 Magic bullet for heart and bone Nature Medicine, 4, 152
159. 1998 The estrogen receptor b subtype: A novel mediator of estrogen action in neuroendocrine systems . Frontiers in Neuroendocrinol, 19, 253-286
160. 1998 Generation and reproductive phenotypes of mice lacking estrogen receptor b Proc.Natl.Acad.Sci. USA, 95, 15677-15682
161. 1998 Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor b Endocrinology, 139, 4252-4263
162. 1998 A regulatory role for RIP140 in nuclear receptor activation Mol. Endocrinol., 12, 864-881
163. 1997 Estrogen receptor b - Getting in on the action Nature Medicine, 3, 493-494
164. 1997 : Human estrogen receptor b-gene structure, chromosomal localization and expression pattern . J. Clin. Endocrinol. Metab., 82, 4258-4265
165. 1997 : Pancreatic b-cells are important targets for the diabetogenic effects of glucocorticoids . J. Clin. Invest. 100, 2094-2098
166. 1997 Insights into the molecular basis of agonism and antagonism in the oestrogen receptor as revealed by complexes with 17b-oestradiol and raloxifene Nature, 389, 753-758
167. 1997 Differential transactivation properties of the estrogen receptor isotypes (a, b): Estrogen-like effects with antiestrogens and antiestrogen effects with estrogen . Science, 277, 1508-1510
168. 1997 Mouse estrogen receptor b forms estrogen response element binding heterodimers with estrogen receptor a a. Mol. Endocrinol. 11, 1486-1496
169. 1997 Role of the Ada Adaptor Complex in Gene Activation by the Glucocorticoid Receptor . Mol. Cell Biol. 3065-3073
170. 1997 Estrogen receptor-b mRNA expression in rat ovary: Down-regulation by gonadotropins Mol. Endocrinol. 11, 172-182
171. 1997 Role of hydrophobic amino acid clusters in the transactivation activity of the human glucocorticoid receptor Mol. Cell Biol., 17, 934-945
172. 1997 Cloning and expression of a novel mammalian thioredoxin J. Biol. Chem., 272, 2936-2941
173. 1996 Cloning of a novel estrogen receptor expressed in rat prostate and ovary Proc.Natl.Acad.Sci. USA 93, 5925-5930
174. 1996 Orphan nuclear receptor - The first eight years. Mol. Endocrinol. 10, 1293-1307
175. 1995 : Cytochrome P450 in the brain: Neuroendocrine functions Frontiers in Neuroendocrinology, 16, 224-236
176. 1995 Solution structure of a mammalian PCB-binding protein in complex with a PCB Nature Struct. Biol.2, 983-989
177. 1995 Structural characterization of a minimal functional transactivation domain from the human glucocorticoid receptor Proc.Natl.Acad.Sci. USA, 92, 1699-1703
178. 1995 Negative cross-talk between ReIA and the glucocorticoid receptor: A possible mechanism for the antiinflammatory action of glucocorticoids Mol. Endocrinol. 9, 401-412
179. 1995 OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor Proc. Natl. Acad. Sci. USA, 92, 2096-2100
180. 1995 Mass spectrometric analysis of a native zinc-finger structure: The glucocorticoid receptor DNA binding domain J. Am. Chem. Society, 117, 3319-3324
181. 1994 : Evolution of distinct DNA-binding specificities within the nuclear receptor family of transcription factors . Proc.Natl. Acad. Sci. USA., 91, 4175-4179
182. 1994 Delineation of a small region within the major transactivation domain of the human glucocorticoid receptor that mediates transactivation of gene expression Proc. Natl. Acad. Sci. USA. 91, 1619-1623
183. 1994 Effect of ethanol on cytochrome P450 in the rat brain. Proc Natl. Acad. Sci. USA., 91, 1019-1023
184. 1993 Structure and function of the DNA-binding domain of the glucocorticoid receptor and other members of the nuclear receptor supergene family Accounts of Chem. Res., 26, 644-650
185. 1993 : A systematic analytical chemistry/cell assay approach to isolate activators of orphan nuclear receptor from biological extracts: characterization of peroxisome proliferator-activated receptor activators in plasma J. Lipid Res., 34, 1583-1591
186. 1993 : Interactions of indolo[3,2-b]carbazoles and related polycyclic aromatic hydrocarbons with specific binding sites for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver . Mol. Pharmacol., 44, 336-345
187. 1993 Interaction of the peroxisome-proliferator-activated receptor and retinoid X receptor Proc. Natl. Acad. Sci. USA, 90, 1440-1444
188. 1993 Direct interaction of the t1 transactivation domain of the human glucocorticoid receptor with the basal transcriptional machinery Mol. Cell. Biol., 13, 399-407
189. 1992 The dioxin and peroxisome proliferator-activated receptors: nuclear receptors in search of endogenous ligands Trends Pharmacol. Sci., 13, 241-245
190. 1992 Importance of growth hormone for the induction of hepatic low density lipoprotein receptors Proc.Natl.Acad.Sci. USA, 89, 6983-6987
191. 1992 Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor Proc.Natl.Acad.Sci. USA, 89, 4653-4657
192. 1991 High level expression of the major transactivation domain of the human glucocorticoid receptor in yeast cells inhibits endogenous gene expression and cell growth Mol. Endocrinology.,5, 1366-1372,
193. 1991 : The Glucocorticoid Receptor Binds to a Sequence Overlapping the TATA Box of the Human Osteocalcin Promoter: a Potential Mechanism for Negative Regulation Mol. Cell. Biol, 11, 3379-3383
194. 1990 Solution structure of the glucocorticoid receptor DNA-binding domain Science, 249, 157-160
195. 1990 Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene Mol.Cell. Biol., 10, 4712-4719
196. 1990 Cloning, structure, and expression of a rat binding protein for polychlorinated biphenyls J. Biol. Chem., 265, 12690-12693
197. 1990 Structural and regulatory analysis of the male-specific rat liver cytochrome P-450g: Repression by continuous growth hormone administration Mol. Endocrinol. 4, 53-58
198. 1989 Transcriptional and posttranscriptional regulation of sexually differentiated rat liver cytochrome P-450 by growth hormone Mol. Endocrinol. 3, 1142-1147
199. 1989 The mechanism of cAMP-induced glucocorticoid receptor expression. Correlation to cellular glucocorticoid response. J. Biol. Chem. 23, 13679-13686
200. 1989 Distribution and regulation of 5a-androstane-3b,17b-diol hydroxylase in the rat central nervous system . Endocrinology 124, 1246-2699
201. 1989 High level expression in Escherichia coli of the DNA-binding domain of the glucocorticoid receptor in a functional form utilizing domain-specific cleavage of a fusion protein J. Biol. Chem. 264, 804-809
202. 1989 Regulation of sexual differentiation in drug and steroid metabolism Trends Pharmacol. Sci., 10, 149-153
203. 1988 Localization of glucocorticoid receptor mRNA in the male rat brain by in situ hybridization Proc. Natl. Acad. Sci. USA 85, 9331-9335
204. 1988 Sex change in cytochrome P-450 phenotype by growth hormone treatment of adult rat hepatocytes maintained in a culture system on matrigel Proc. Natl. Acad. Sci. USA 85, 9783-9787
205. 1988 Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation Cell 55, 361-369
206. 1988 : Requirement of hormone for thermal conversion of the glucocorticoid receptor to a DNA-binding state Nature 33, 686-688
207. 1988 Identification of hormone-interacting amino acid residues within the steroid-binding domain of the glucocorticoid receptor in relation to other steroid hormone receptors J. Biol. Chem. 263, 6843-6846
208. 1988 Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene Genes & Development 2, 1144-1154
209. 1988 cDNA cloning, sequence, and regulation of a major female-specific and growth hormone-inducible rat liver cytochrome P-450 active in 15b-hydroxylation of steroid sulfates Proc. Natl. Acad. Sci. USA 85, 4214-4217
210. 1988 : A progesterone responsive element maps to the far upstream steroid dependent DNase hypersensitive site of chicken lysozyme chromatin EMBO J. 7, 2063-2073
211. 1987 Biochemistry, molecular biology, and physiology of the glucocorticoid receptor Endocrine Reviews 8, 185-234
212. 1987 The molybdate-stabilized non-activated glucocorticoid receptor contains a dimer of Mr 90,000 non-hormone-binding protein J. Biol. Chem. 262, 11803-11806
213. 1987 Domain structure of the glucocorticoid receptor protein. Proc. Natl. Acad. Sci. USA 84, 4437-4440
214. 1986 Stoichiometric analysis of the specific interaction of the glucocorticoid receptor with DNA J. Biol. Chem. 261, 11770-11778
215. 1986 Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA . Cell 46, 389-399
216. 1986 Down-regulation of glucocorticoid receptor mRNA by glucocorticoid hormones and recognition by the receptor of a specific binding sequence within a receptor cDNA clone Proc. Natl. Acad.Sci. USA 83, 5899-5903
217. 1985 Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptor Endocrinology 117, 1803-1812
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