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Peer Reviewed Papers, Books, Chapters

Year Title Citation Authors
1. 2011 Basal Protein Kinase Cδ Activity is Required for Membrane Localization and Activity of TRPM4 Channels in Cerebral Artery Smooth Muscle Cells Channels (Austin) 1:5(3), 2011.
2. 2011 Sustainable TRPM4 Channel Activity Following Restoration of Cytosolic Ca2+ Buffering in Freshly Isolated Cerebral Smooth Muscle Cells Biophysical Society Annual Meeting
3. 2010 Pharmacological Inhibition of TRPM4 Hyperpolarizes Vascular Smooth Muscle Am. J. Physiol. (Cell. Physiol.), 299(5):C1195-202, 2010.
4. 2010 Vasoconstriction Resulting From Dynamic Membrane Trafficking of TRPM4 in Vascular Smooth Muscle Cells Am. J. Physiol. (Cell. Physiol.), 299(3):C682-94, 2010.
5. 2010 Local Regulation of L-type Channels by Reactive Oxygen Species Circ Res., 107(8):1002-10, 2010
6. 2010 Family Feud: Crosstalk Between TRPC Channels In Vascular Smooth Muscle Cells During Vasoconstrictor Agonist Stimulation J. Physiol., 588(19):3637-3638
7. 2010 Dual Role for Sarcoplasmic Reticulum Calcium Stores in the Regulation of Smooth Muscle Cell Membrane Potential FASEB Summer Conference: Calcium and Cell Function
8. 2010 The Putative TRPM4 Blocker 9-Phenanthrol Causes Smooth Muscle Cell Hyperpolarization and Arterial Dilation FASEB J., 24:603.14
9. 2010 Disruption of caffeine-induced constriction in isolated cerebral arteries following treatment with siRNA against STIM 1 FASEB J., 24:603.15, 2010
10. 2010 Local Regulation of L-type Calcium Channels by Reactive Oxygen Species FASEB J., 24:603.11, 2010
11. 2010 “Vanilloid and Melastatin Transient Receptor Potential Channels in Vascular Smooth Muscle” Microcirculation 17, 237–249, 2010. (invited review).
12. 2010 “Transient Receptor Potential Channels and Vascular Function” Clin Sci (Lond) 119(1):19-36, 2010. PMID: 20370719 (invited review).
13. 2010 “Endothelium-Dependent Cerebral Artery Dilation Mediated by Transient Receptor Potential and Ca2+-Activated K+ Channels” J. Cardiovascular Pharmacology, in press, 2010
14. 2010 A Dietary Agonist of Transient Receptor Potential Cation Channel V3 Elicits Endothelium-Dependent Vasodilation Mol. Pharmacol. 77(4):612-20, 2010. PMID: 20086034
15. 2010 Ca2+ Release from the Sarcoplasmic Reticulum is Required for Sustained TRPM4 Activity in Cerebral Artery Smooth Muscle Cells Am. J. Physiol. (Cell. Physiol.), 299(2):C279-88, 2010
16. 2009 Cerebral Artery Dilation Mediated by Endothelial TRPA1 and Ca2+-Activated K+ Channels. Circ Res. 104(8):987-94, 2009.
17. 2009 Dynamic PKCδ-Mediated Trafficking of TRPM4 Regulates Smooth Muscle Excitability FASEB J., 23:1018.2 2009
18. 2009 TRPV4-Dependent Dilation of Peripheral Resistance Arteries Influences Arterial Pressure Am. J. Physiol. (Heart Circ. Physiol.), 297: H1096-H1102, 2009. PMCID: PMC2755979
19. 2009 Phospholipase Cγ1 is Required for Pressure-Induced Vasoconstriction of Cerebral Arteries. FASEB J., 23:613.16 2009.
20. 2009 Reduction in TRPC4 Expression Specifically Attenuates G-Protein Coupled Receptor-Stimulated Increases in Intracellular Calcium in Human Myometrial Cells Cell Calcium, 46(1):73-84, 2009.
21. 2009 Sustainable TRPM4 Channel Activity in Freshly-Isolated Cerebral Artery Smooth Muscle Cells. FASEB J., 23:1000.5 2009
22. 2008 TRPV3 and TRPA1 Agonists Increase Intracellular Ca2+ Levels in Native Cerebral Artery Endothelial Cells FASEB J., 22:964.17 2008
23. 2008 Disruption of Vasoconstrictor Responses in Isolated Cerebral Arteries Following Treatment with siRNA Against TRPM4 FASEB J., 22:1151.19 2008
24. 2008 Membrane Trafficking of TRPM4 in Smooth Muscle Cells FASEB J., 22:937.4 2008.
25. 2008 “TRP Channels, Myogenic Tone, and Autoregulation of Cerebral Blood Flow” Clinical and Experimental Physiology & Pharmacology
26. 2007 “Coupling a Change in Intraluminal Pressure to Vascular Smooth Muscle Depolarization: Still Stretching for an Explanation” Am. J. Physiol. (Heart Circ. Physiol.) 292:H2570-H2572 2007.
27. 2007 Protein Kinase C Regulates Vascular Myogenic Tone Through Activation of TRPM4 Am. J. Physiol. (Heart Circ. Physiol.) 292:H2613-H2622, 2007.
28. 2006 Central Role of Ca2+ Dependent Regulation of Vascular Tone in vivo J. Appl. Physiol. 101: 10-11 2006
29. 2006 Molecular Diversity of Receptor Operated Channels in Vascular Smooth Muscle: A Role for Heteromultimeric TRP Channels? Circ. Res. 98(12):1462-4, 2006
30. 2006 Protein Kinase C-Dependent TRPM4 Activation Regulates Cerebral Artery Tone FASEB J. 20 (4): A732-A732, 2006
31. 2005 TRPV4 Forms a Novel Ca2+ Signalling Complex with Ryanodine Receptors and BKCa Channels Circ. Res. 97(12):1270-9, 2005
32. 2005 Pressure-Induced Smooth Muscle Cell Depolarization in Pulmonary Arteries from Control and Chronically Hypoxic Rats Does Not Cause Myogenic Vasoconstriction J. Appl. Physiol. 98(3):1119-24, 2005
33. 2005 TRPC3 Channels Mediate Agonist-Induced Depolarization of Cerebral Artery Smooth Muscle Cells Am. J. Physiol. 288 (Heart Circ. Physiol.):H2055-2061, 2005.
34. 2005 “EDHF redux: EETs, TRPV4, and Ca2+ Sparks” Circ. Res. 97(12):1209-10 2005.
35. 2005 Brayden. Epoxyeicosatrienoic Acid-Dependent TRPV4 Activation Increases Spontaneous Transient Outward Current Frequency in Cerebral Arterial Smooth Muscle. FASEB J., 19(5):A1627, 2005.
36. 2004 Critical Role for Transient Receptor Potential Channel TRPM4 in Myogenic Constriction of Cerebral Arteries Circ. Res. 95:922-929, 2004.
37. 2004 TRPC3 Channels Mediate Agonist-Induced Depolarization of Cerebral Artery Smooth Muscle Cells FASEB J. 18(4): A644, 2004
38. 2004 Transient Receptor Potential Channel TRPM4 Contributes to Myogenic Vasoconstriction of Cerebral Arteries FASEB J. 18(4): A268, 2004
39. 2004 Disruption of Smooth Muscle Gap Junctions Attenuates Myogenic Vasoconstriction of Mesenteric Resistance Arteries Am. J. Physiol. 287 (Heart Circ. Physiol.):H2677-H2686, 2004
40. 2003 Vasoconstrictor Sensitivity to Endothelin-1 Following Intermittent Hypoxia FASEB J. 17(4):A334, 2003
41. 2003 Increased Nitric Oxide Production Following Chronic Hypoxia Contributes to Attenuated Systemic Vasoconstriction Am. J. Physiol. 284(5) (Heart Circ. Physiol.):H1655-H1661, 2003.
42. 2003 Cytochrome P450 Epoxygenase Products Contribute to Attenuated Vasoconstrictor Responsiveness Following Chronic Hypoxia Am. J. Physiol. 285(1) (Heart Circ. Physiol.):H127-36, 2003
43. 2003 Increased Nitric Oxide Production Following Chronic Hypoxia Contributes to Attenuated Systemic Vasoconstriction FASEB J. 17(4): A576, 2003
44. 2002 Developmental Differences in Pulmonary eNOS Expression in Response to Chronic Hypoxia in the Rat J. Appl. Physiol. 93:311-318, 2002.
45. 2002 Estradiol Attenuates Hypoxia-Induced Pulmonary Endothelin-1 Gene Expression Am J. Physiol. 283 (Lung Cell. Mol. Physiol.):L86-L93, 2002
46. 2002 Blunted Myogenic Reactivity Following Chronic Hypoxia is Endothelium Dependent. FASEB J. 16(4):A519, 2002
47. 2002 Cytochrome P450 Epoxygenase Products Contribute to Attenuated Vasoconstrictor Responsiveness Following Chronic Hypoxia Circulation 106(19):II-317, 2002
48. 2002 Hypoxia-Induced Pulmonary Endothelin-1 Expression is Unaltered by Nitric Oxide J. Appl. Physiol. 92 (3):1152-1158
49. 2002 Endothelium-Dependent Blunting of Myogenic Responsiveness Following Chronic Hypoxia Am. J. Physiol. 283(6) (Heart Circ. Physiol.):H2202-9, 2002
50. 2002 48-hour Hypoxic Exposure Results in Endothelium-Dependent Systemic Vascular Smooth Muscle Cell Hyperpolarization Am J. Physiol. 283 (Regulatory Integrative Comp. Physiol):R79-R85, 2002
51. 2001 Estradiol Attenuates Hypoxia-Induced Endothelin-1 Gene Expression FASEB J. 15(4):A156, 2001
52. 2001 Chronic Hypoxia Results in Endothelium-Dependent Vascular Smooth Muscle Hyperpolarization. 34th International Congress of Physiological Sciences, Christchurch, NZ, 2001
53. 2001 Chronic Hypoxia is Associated with Vascular Smooth Muscle Hyperpolarization and Blunted Vasoconstrictor Responses FASEB J. 15(4):A104, 2001
54. 2000 Developmental Differences in Pulmonary eNOS Expression in Response to Chronic Hypoxia in the Rat. FASEB J. 14(4); A125, 2000
55. 2000 Nitric Oxide Attenuates Hypoxia-Inducible Factor-Mediated Endothelin-1 Gene Expression FASEB J. 14(4):A123, 2000.
56. 1999 Unaltered Vasoconstrictor Responsiveness After iNOS Inhibition in Lungs From Chronically Hypoxic Rats Am. J. Physiol. 276 (Lung Cell. Mol. Physiol. 20): L122-L130, 1999.
57. 1999 Adenovirus-mediated iNOS gene transfection attenuates U-46619 induced pulmonary arterial constriction in isolated rat lungs Pediatr. Res. 45(4): 297A, 1999
58. 1989 Identification of Polypeptides Encoded by Cloned pJM1 Iron-Uptake DNA Isolated from Vibrio anguillarum 775 J. Bacteriology 171: 2293 – 2302, 1989
59. 1986 Distribution and Evolution of Sequence Characteristics in the E. coli Genome J. Biomol. Struct. and Dyn. 4: 291 – 307, 1986


4th Annual Pharma R&D Asia Congress
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