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Speaking/Presenting-Abstract/Poster at Mtg

Topic Authors / presenters Event name Event date
1. Development of novel Alzheimer disease biomarkers: oligomeric Ab and apoE/Ab complex levels. Tai, L., Jungbauer, L.M., Estus S., Bu, G., Gylys K.H., M.J. LaDu. Young Investigator Scholarship and Outstanding Young Investigator award, Alzheimer’s Drug Discovery foundation, 7th Annual Drug Discovery for Neurodegenerative Disease conference, San Francisco, CA. January, 2013
2. The effect of apoE genotype on apoE and A42 solubility and cellular distribution in vitro Nwabuisi-Heath, E., Tai, L., Yu, C., and M.J. LaDu Talk, American Society for Neurochemistry. Program No. OP03-02. January, 2012
3. Synaptic ApoE-A interactions: relation to stage of AD pathology. ApoE, Alzheimer’s, and Lipoprotein Biology Bilousova, T., Gonzalez, B., Tai, L.M., Watson, T., LaDu, M.J., and K.H. Gylys. Keystone Symposia. January, 2012
4. Apolipoprotein E isoform effects stability of apoE/Aβ complex. ApoE, ApoE receptors and neurodegeneration Tai, L., Jungbauer, L.M., Roeske, S.K., Yu, C. and M.J. LaDu Selected for “Hot Topic” talk, ApoE, ApoE Receptors and Neurodegeneration Symposium: ApoE Receptors, Mayo, Jacksonville, FL. January, 2012
5. Development of novel Alzheimer disease Biomarkers: oligomeric Ab and apoE/Ab complex levels Tai, L., Jungbauer, L.M., Youmans, K.L., Estus S., M.J. LaDu Postdoctoral fellows and residents Gold First Prize, College of Medicine Research Forum, UIC, Chicago, IL January, 2012
6. Modulation of human apoE-isoform levels as a therapeutic target in a new AD mouse model Tai, L.M., Luo, J., Thatcher, G., and M.J. LaDu International Society for Neuroscience January, 2012
7. Apoliporotein E isoform effects stability of apoE/Av complex Tai, L.M., Jungbauer, L., Roeske, S.K., Yu, C., and M.J. LaDu American Society for Neurochemistry (abstract). Program No. PSM06-13 January, 2012
8. Apolipoprotein E Genotype Alters the Protective Effects of Estrogen on A42 Pathology Yu, C., Kunzler, K., Youmans, K.L., Rajapaksha, T., Vassar, R., and M.J. LaDu. In Society for Neuroscience (abstract). Program No. 769.21/I2 January, 2011
9. Apolipoprotein E4 delays spine formation and accelerates loss of mature spines, in vitro Nwabuisi-Heath, E., LaDu. M.J., and C. Yu. In Society for Neuroscience (abstract). Program No. 876.02/I2 January, 2011
10. Selective increases in soluble apolipoprotein E4 and A42 in the AD-susceptible brain. LaDu, M.J., Youmans, K.L., Tai, L.M., Jungbauer, L.M., Gao, W., Berbaum, M., Bu, G., and C. Yu. In Society for Neuroscience (talk). Program No. 118.06 January, 2011
11. Apolipoprotein E effects on the progression of A pathology in vivo Youmans, K., Tai, L.M., Weeber, E., Rebeck, G.W., Bu, G., Yu, C., and M.J. LaDu. American Society for Neurochemistry (abstract). Program No. PTW11-04. January, 2011
12. MOAB-2: a new monoclonal antibody specific for Av. LaDu, M.J., Youmans, K., Tai, L.M, and C. Yu. American Society for Neurochemistry (abstract). Program No. PTW11-07. January, 2011
13. Apolipoprotein E4 delays spine formation and accelerates loss of mature spines, in vitro Nwabuisi, E., LaDu, M.J., and C. Yu. American Society for Neurochemistry (abstract). Program No. PSM06-03. January, 2011
14. Apolipoprotein E effects on the progression of Ab pathology in the EFAD mouse model of Alzheimer’s disease Youmans, K.L., Tai, L.M., Laxton, K.T., Jungbauer, L.M., Kim, J., Weeber, E., Rebeck, G.W, Bu, G., Yu, C., and M.J. LaDu. In Society for Neuroscience (talk). Program No. 118.05 January, 2011
15. ApoE pharmacogenomic effects on NSAID and dietary fatty acids on amyloid in Alzheimer model mice Cole, G.M., Ganti, D.J., Ma, Q.-L., Jones, M.R., Alaverdyan, M., Yang, F., Chen, P., Sullivan, P.M., LaDu, M.J., and S.A. Frautschy In Society for Neuroscience (abstract). Program No. 532.04 January, 2011
16. Prion protein inhibits kinesin-1 and dynein based fast axonal transport Pigino, G.F., Song, Y., Morfini, G., Ma, S., Lindquist, S., Jungbuaer, L., LaDu, M.J., and S. Brady. In Society for Neuroscience (abstract). Program No. 424.13 January, 2011
17. Detection methods for identifying endogenous apolipoprotein E/A complexes Tai, L.M., Jungbauer, L.M., Youmans, K.L., Yu, C., Getz, G.S., Reardon, C., and M.J. LaDu In Society for Neuroscience (abstract). Program No. 47.04/N9 January, 2011
18. Apolipoprotein E effects on Ab solubility in vivo Yu, C., Youmans, K., Tai, L.M, Bu, G., and M.J. LaDu American Society for Neurochemistry (abstract). Program No. PTW11-06. January, 2011
19. Human apoE isoform-specific cellular distribution affects the progression of A42 pathology in a novel transgenic mouse model Youmans, K., Laxton, K., and M.J. LaDu. Selected for “Hot Topic” talk, ApoE, ApoE Receptors and Neurodegeneration Symposium: ApoE in the CNS and periphery, UIC, Chicago, IL. January, 2010
20. The effects of human apoE on A pathology in a novel transgenic mouse model Youmans, K., Laxton, K., Jungbauer, L., Yu, C., and M.J. LaDu. In Society for Neuroscience (talk). Program No. 320.4/C.02. January, 2010
21. The effects of human apoE, A42 pathology and synaptic loss in a novel transgenic mouse model. Youmans, K., Laxton, K., and M.J. LaDu Talk, American Society for Neurochemistry, Program No. OP01-04. January, 2010
22. Use of array tomography to assess the effects of apolipoprotein E and amyloid-beta on synaptic loss. Laxton, K., Hughes, W., Smith, S. and M.J. LaDu. In Society for Neuroscience (abstract). Program No. 317.7/B118 January, 2009
23. The effect of A42 levels and solubility on apoE and synaptic proteins Youmans, K., Yu, C., Maus, E., Vassar, R., and MJ. LaDu In Society for Neuroscience (abstract). Program No. 627.5/I3 January, 2009
24. Characterization of Alexa Fluor@488-labeled A42 oligomers:Additional structural and functional insights. Jungbauer, L.M., Yu, C., Teplow, D., and M.J. LaDu In Society for Neuroscience (abstract). Program No. 627.9/I7 January, 2009
25. AFM-characterized fluorophore-labeled A42 oligomers for cellular trafficking and toxicity studies in neuronal cells. Jungbauer, L.M., Yu, C., and M.J. LaDu Brain Research Foundation Best Poster in Postdoc category at Neuroscience Day. January, 2008
26. Intraneuronal amyloid-42: Internalization and neurotoxicity of oligomeric A42 Zhu, Y., Jungbauer, L.M., LaDu, M.J., and C. Yu. In Society for Neuroscience (abstract). Program No. 830.8/F10 January, 2008
27. ApoE-genotype specific response to accute inflammation and synaptic loss in vivo. Zhu, Y., Nwabuisi, E., and M.J. LaDu In Society for Neuroscience (abstract). Program No. 52.16/Z5 January, 2008
28. AFM-characterized fluorophore-labeled A42 oligomers for cellular trafficking and toxicity studies in neuronal cells Jungbauer, L.M., Yu, C., and M.J. LaDu In Society for Neuroscience (abstract). Program No. 243.14/L4 January, 2008
29. The effects of human apoE isoform on spatial learning and markers of synaptic and structural plasticity in targeted replacement mice LaDu, M.J., Pych, J.C., Zhu. Y.G., and A.M. Wyrwicz In Society for Neuroscience (abstract). Program No. 45.16/V6 January, 2008
30. Lighting up A42 oligomers: effects of fluorophore-modification on assembly and function. Jungbauer, L.M., Yu, C., and M.J LaDu Talk, AFM BioMed Conference. January, 2008
31. The effect of apolipoprotein E on the internalization and neurotoxicity of oligomeric -amyloid-42 in neurons Zhu, Y.G., LaDu, M.J., and C. Yu. In Society for Neuroscience (abstract). Program No. 484.14/V8. January, 2007
32. Cognitive effects of synthetic and neuron-derived soluble A oligomers. Cleary, J.P., LaDu, M.J., Hofmeister, J., Lesne, S., Reed, M., and K.H. Ashe In Society for Neuroscience (abstract). Program No. 856.11. January, 2007
33. Structural and functional interactions between apoE, apoE receptors and A42 LaDu, M.J., Manelli, A., Stine, W.B., Trommer, B., Bulfinch, L., Yungbauer, L.M., Youmans, K.L., Zhu, Y., and C. Yu. American Society for Neurochemistry (abstract). January, 2007
34. Isoform difference in apoE proteolysis by cathepsin D and its interaction with the amyloid- peptide Zhou, W., LaDu, M.J., and K.A. Crutcher. In Society for Neuroscience (abstract). Program No. 466.8/JJ10. January, 2006
35. Effect of A structure and human apoE isoform on primary co-cultures of neurons and glia. Bulfinch, L., Manelli, A.M., Sullivan, P., and M.J. LaDu Winter Brain, Steam Boat. January, 2006
36. Mecamylamine suppresses hippocampal long-term potentiation in C57BL/6 mice but not in human apoE4-targeted replacement mice Yun, S.H., Park, K.A., Sullivan, P., Pasternak, J.F., LaDu, M.J., and B.L. Trommer. In Society for Neuroscience (abstract). Program No. 494.411 January, 2005
37. Role of ERK signaling in apoE-dependent neuroplasticity Teter, B., Zhao, L., LaDu, M.J., and G. M. Cole. In Society for Neuroscience (abstract). Program No. 442.418. January, 2004
38. Effect of apoE on glial activation by oligomeric versus fibrillar A1-42 Cao, W., Manelli, A. M., and M. J. LaDu. In Society for Neuroscience (abstract). Program No. 442.441. January, 2004
39. Effect of A structure and human apoE isoform on primary co-cultures of neurons and glia. Manelli, A. M., Sullivan, P.M., and M. J. LaDu. In Society for Neuroscience (abstract). Program No. 442.442. January, 2004
40. The Effects of isoform and protein conformation on apoE: A interactions Stine, W. B., Manelli, A. M., and M. J. LaDu. In Society for Neuroscience (abstract). Program No. 442.412. January, 2004
41. Amyloid-1-42 induced neurotoxicity in cells co-cultured with glia from apoE targeted replacement mice Manelli, A. M., Sullivan, P.M., and M. J. LaDu In Society for Neuroscience (abstract) Program No. 407.418. January, 2003
42. Synaptic plasticity in apoE replacement mice Shah, C., Gamkrelidze, G., Yun, S.H., Pasternak, J.F., Sotak, M., Ye, G., Sullivan, P.M., LaDu, M.J., and B.L. Trommer In Society for Neuroscience (abstract). Program No. 730.731. January, 2003
43. Apolipoprotein E4 potentiates microglial inflammatory responses Chen, S., Averett, N. T., LaDu, M.J., Manelli, A.M., May, W., and M. D. Ard. In Society for Neuroscience (abstract). Program No. 407.413. January, 2003
44. Antibodies specific for toxic amyloid- oligomers. Stine, W. B., Manelli, A.M., Alkhaleefa, N., Fu, Y., Guillozet, A., Horowitz, P., Binder, L., and M. J. LaDu. In Society for Neuroscience (abstract). Program No. 841.842. January, 2003
45. Microglial inflammatory response is modulated by apolipoprotein E and amyloid- protein combinations Ard, M.D., Chen, S., Averett, N.T., Manelli, A.M., and M.J. LaDu In Society for Neuroscience (abstract). Program No. 723.721. January, 2002
46. ApoE down regulates pro-inflammatory responses induced by oligomeric A in activated glia. Guo, L., Ladu, M.J., and L. J. Van Eldik In Society of Neuroscience (abstract). Program No. 883.812. January, 2002
47. Glial activation by oligomeric versus fibrillar amyloid- 1-42. Manelli, A.M., Guo, L., White, J. A., VanEldik, L.J., and M.J. LaDu. In Society for Neuroscience (abstract). Program No. 193.199. January, 2002
48. In vitro characterization of soluble oligomeric and fibrillar forms of amyloid. Stine, W. B., Dahlgren, K.N., Krafft, G.A., and M. J. LaDu. In Society for Neuroscience (abstract). Program No. 688.613. January, 2002
49. ApoE affects the aggregation of A1-42 into oligomeric and fibrillar species in vitro. Stine, W. B., Manelli, A.M., Baker, L.K., and M. J. LaDu. In Society of Neuroscience (abstract). Program No. 428.426/V 27. January, 2001
50. Synthesis and characterization of a targeted fluorescently labeled A Sujatha, K., Stine, B., Manelli, A., Dahlgren, K., LaDu, M.J., and G. Krafft. American Chemical Society. January, 2001
51. Inhibition of amyloid generated toxicity: Design, synthesis and evaluation of novel fluorinated alcohol derivatives. Sujatha, K., Stine, B., Manelli, A., Dahlgren, K., LaDu, M.J., and G. Krafft. American Chemical Society. January, 2001
52. Differential effect of A1-42 conformation and ApoE isoform on LTP Wang, H. W., Manelli, A., Baker, L., Ye, G.L., Pasternak, J.F., LaDu, M.J., and B. L. Trommer. In Society for Neuroscience (abstract). Program No. 752.18 January, 2001
53. Neurotoxicity included by oligomeric versus fibrillar A1-42. Manelli, A. M., Dahlgren, K., Krafft, G.A. and M. J. LaDu In Society of Neuroscience (abstract). Program No. 322.312. January, 2001
54. Apolipoprotein E and its receptors mediate the effects of -amyloid-induced inflammation in primary astrocyte cultures LaDu, M.J., Shah, J., Reardon, C., Getz, G.S., Bu, G., Hu, J., and L. Van Eldik Neurobiology of Aging 21:S148. International Conference on Alzheimer disease January, 2000
55. Specific domains of -amyloid influence its association with apolipoprotein E3. G.W. Munson, Roher A.E., Kuo, Y.M., Gilligan, S.M., Reardon, C.A., Getz, G.S., M.J. LaDu. In Society for Neuroscience (abstract). Program No. 543.7. January, 1999
56. amyloid associates with CNS lipoproteins LaDu, M.J., Lukens, J., Gilligan, S., Holtzman, D.M., Van Eldik, L.J., Getz, G. S., and C.A. Reardon In Society for Neuroscience (abstract). Program No. 670.13. January, 1998
57. Lipoprotein secretion by primary astrocytes from wild type apoE null and human apoE transgenic mice Fagan, Holtzman, D., Sun Y., Wu, S., Getz, G. S., Reardon, C.A., Lukens, J., Shah, J.A., M.J. LaDu. In Society for Neuroscience (abstract). Program No. 670.12. January, 1998
58. Characterization of apolipoprotein E- containing particles from CSF and cultured astrocytes. Gilligan, S.M., Reardon, C.A., Getz, G.S., Van Eldik, L.J., and D.M. Holtzman In Society for Neuroscience (abstract). Program No. 323.18 January, 1997
59. Role of LPR in mediating the isoform-specific effects of apolipoprotein E on cell survival and -amyloid induced toxicity in rat hippocampal neuron cultures Jordán, J., Galindo, M.F., Miller, R.J., Reardon, C.A., Getz, G.S., and M.J. LaDu. In Society for Neuroscience (abstract). Program No. 861.8. January, 1997
60. Effect on native apolipoprotein E isoforms on -amyloid induced activation of rat glial cultures Van Eldik, L.J., Hu, J., Akama, K., and M.J. LaDu. In Society for Neuroscience (abstract). Program No. 828.3. January, 1996
61. Isoform-specific effect of apolipoprotein E on -amyloid induced toxicity in rat hippocampal pyramidal neuronal cultures Miller, R.J., Galindo, M.F., Jordán, J., Lukens, J.R., Getz, G.S., and M.J. LaDu In Society for Neuroscience (abstract). Program No. 828.7. January, 1996
62. Distribution of endogenous and exogenous -amyloid in plasma lipoproteins from apolipoprotein E genotyped donors LaDu, M.J., Falduto, M.F., Lukens, J.R., Getz, G.S., and C.A. Reardon. In Society for Neuroscience (abstract). Program No. 828.6 January, 1996
63. Activation of cultured astrocytes by amyloid peptide Akama, K.T., Hu, J., Zhou, L.M., Krafft, G.A., Van Eldik, L,J.,and M.J. LaDu In Society for Neuroscience (abstract). January, 1995
64. Isoform-specific binding of N-terminal fragments and full apolipoprotein E to -amyloid Monach, P.A., Reardon, C.A., Getz, G.S., Meredith, S.C., and M.J. LaDu In Society for Neuroscience (abstract). January, 1995



Site wide Speaking/Presenting-Abstract/Poster at Mtg

Presentation Event Month, Year
Modulation of Human apoE Isoform Levels as a Therapeutic Target 14th International Conference on Alzheimer's Drug Discovery September, 2013

4th Annual Pharma R&D Asia Congress
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