3D Tissue Models

Dominique Bonnet

TypeWhite Paper Summary

The Cancer Research UK London Research Institute (LRI) houses 46 research groups based at two locations: Lincoln's Inn Fields (LIF) laboratories in central London, and Clare Hall (CH) laboratories on London's outskirts at South Mimms, Hertfordshire. Both laboratories boast state-of-the-art instrumentation and access to first-class core and service facilities. Eleven of the group leaders are Fellows of the Royal Society, two have received knighthoods and two are Nobel Laureates.

Lincoln's Inn Fields labs on left and Clare Hall labs on right

The Lincoln's Inn Fields Laboratories (left) and the Clare Hall Laboratories (right)

The LRI has an international reputation for its research in the basic biology of cancer. Themes of research are signal transduction (biology of tissues and organs, and molecular cell biology) and genome integrity (cell cycle and chromosomes and DNA repair).

The LRI has its origins as the principal research facilities of the Imperial Cancer Research Fund which was founded in 1902 - the first specialist cancer research charity in the United Kingdom. In 2002, the Imperial Cancer Research Fund and the Cancer Research Campaign merged to form Cancer Research UK, the largest cancer charity in Europe with an annual scientific spend of £257 million (in 2005/06). The LRI is the largest core-funded institute in Cancer Research UK's portfolio.

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Name:Dominique Bonnet

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