Kinase Inhibitor Chemistry - Charting the Chemical Space
1775 East Mission Bay Drive
San Diego, CA 92109
Kinase Inhibitor Chemistry - Charting the Chemical Space
Cambridge Healthtech Institute

Schedule of Presentations:

Tuesday, April 7, 2009
12:30:00 Registration
13:30:00 Chairperson’s Opening Remarks
13:40:00 Exploiting Kinase Polypharmacology in Cell Cycle Regulation via High-Content Imaging Jeffrey Sutherland
14:10:00 Binding Modes of Fragment-Like Kinase Inhibitors Keith Constantine
14:40:00 Title to be Announced Peter A. Petillo
15:10:00 Sponsored Presentation (Opportunity Available)
15:25:00 Networking Refreshment Break in the Exhibit Hall
16:05:00 From HTS to Clinical Compound: Discovery of Potent and Exquisitely Selective C-Met Inhibitor PF-4217903 Jingrong Jean Cui
16:35:00 Identification of Potent and Selective Inhibitors of Trk Kinases Tao Wang
17:05:00 Topic 1: discussing pre-clinical challenges Stephan K. Grant
17:05:00 Breakout Discussions with the Experts
17:10:00 Topic 2: Residence time - the new dimension for lead optimization Doris Hafenbradl
17:20:00 Topic 3: Fragment-Based Drug Design Patrick P. Zarrinkar
18:15:00 End of Day
Wednesday, April 8, 2009
07:45:00 Morning Coffee
08:15:00 Chairperson’s Remarks
08:20:00 KEYNOTE PRESENTATION A Helix Scaffold for the Assembly of Active Protein Kinases Alexandr Kornev
09:00:00 Breakout Discussion Feedback by Moderators
09:30:00 Iterative Kinase Medium-Throughput Screening with 2D profile-QSAR and 3D AutoShim Models Eric Martin
10:00:00 Networking Coffee Break in the Exhibit Hall
10:45:00 Fragment-Based Design of Non-ATP Competitive Kinase Inhibitors through REPLACE Campbell McInnes
11:15:00 Fragment Based Lead Generation for Novel Kinase Inhibitors: Frontloading-Binding-Kinetic Properties Gerhard Mueller
11:45:00 Panel Discussion
12:15:00 Luncheon in the Exhibit Hall (Last Chance for Exhibit Viewing)
13:55:00 Chairperson’s Remarks Steven Muskal
14:00:00 Using Receptor-site Similarity to LigandCross into new Diversity Steven Muskal
14:30:00 Discovery and Preclinical Development of Novel Protein Kinase C Inhibitors Stefan Grant
15:00:00 Networking Refreshment Break
15:20:00 MEK Inhibitor for Oncology and Inflammation – A Developing Story Jeffrey N. Miner
15:50:00 Src Family Kinase Inhibitors for Cancer Therapy Richard Jove
16:20:00 Panel Discussion: What have we learned? The take home message.
16:50:00 End of Conference
3D Tissue Models
About Us | Privacy Policy | Site Map | FAQs | Advertise With Us | Community promotes research and ranks life scientists working in the life science spectrum involving biotechnology,
drug discovery, genomics, microbiology, neuroscience, medicine, pharmacology, cell biology, and molecular biology.