3D Tissue Models
Immunogenicity Prediction and Reduction
Loews Philadelphia Hotel
1200 Market Street
Philadelphia, Pennsylvania
 Immunogenicity Prediction and Reduction   
Cambridge Healthtech Institute 

Schedule of Presentations:

Wednesday, October 28, 2009
14:00:00 Chairperson’s Opening Remarks
14:05:00 Impact of the Route of Administration on Immunogenicity of a Biotherapeutic: Pre-clinical Case Studies Featured Presentation Boris Gorovits
14:35:00 Pre-clinical Studies and Clinical Plans for Tolerance Induction KEYNOTE Richard Garman
15:05:00 Benefits of Fusion of PEG-like Protein Sequences to Reduce Immunogenicity Volker Schellenberger
15:35:00 Networking Refreshment Break, Poster and Exhibit Viewing
16:00:00 Detection of Protein Structures Responsible for Immunogenicity to Provide Safer, Less Immunogenic Biopharmaceuticals Barend Bouma
16:30:00 Sponsored Presentation
17:00:00 Break Out Sessions
17:05:00 Table 1: How Serious are Antibodies to Protein and Antibody Therapeutics for the Industry? Fiona A. Harding
17:10:00 Table 2: How Useful are the Current De-Immunization Technologies for the Industry? Richard Garman
17:30:00 Networking Cocktail Reception in the Exhibit Hall
18:30:00 End of Day One of Immunogenicity Prediction and Reduction
Thursday, October 29, 2009
08:30:00 Chairperson’s Remarks
08:35:00 In silico Immunogenicity Assessment and Development of Immune Responses in Vivo Paul W.H.I. Parren
09:05:00 In vitro and in silico Methods to Identify T-cell Epitopes: Interpreting the Data in a Clinically Relevant Way Philippe Stas
09:35:00 Engineering Antibodies for Reduced Immunogenic Potential: Humira Fiona A. Harding
10:05:00 Sponsored Presentation
10:25:00 Networking Coffee Break, Poster and Exhibit Viewing
11:00:00 Industrial Protein Engineering for Selection of Non-immunogenic Protein Mutations David Estell
11:30:00 Clinical Data Showing Deimmunization without Affecting Efficacy Featured Presentation Matthew Baker
12:00:00 Selective Removal of B Cell Epitopes from Bacterial Proteins Tina Furebring
12:30:00 End of Immunogenicity Prediction and Reduction
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