Lipid signaling Pathways in Cancer
Hyatt Grand Champions Resort & Spa
Indian Wells
mm, CA
1.PKC as a Model DAG Target,2.Diacylglycerol Targets in Cancer 3.Termination of DAG Signaling 4 Arachidonate-Derived Bioactive Lipids and Cancer 5. Regulation of Phosphoinositide Metabolism 6. Phosphoinositide Signaling Pathways in Cancer 7. Ceramide and Sphingolipids 8. Lipid Microdomains and Modifications.

Schedule of Presentations:

Saturday, August 11, 2007
12:00:00 New Presentation
12:00:00 New Presentation
16:00:00 Conference Registration
18:00:00 FASEB Opening Reception
19:00:00 Dinner
20:45:00 PHLPPing the Switch: Signal Propagation and Termination in the Protein Kinase C and Akt Lipid Signaling Pathways Alexandra C Newton
22:00:00 Closing
Sunday, August 12, 2007
07:30:00 Breakfast
09:00:00 Molecular aspects of PKC signaling Peter J Parker
09:35:00 “C1, see them all? Opportunities for selectivity with ligands targeted to C1 domains Peter M Blumberg
10:10:00 Group photo and FASEB Sponsored Coffee Break
11:00:00 Par-4 and p62: two atypical PKC partners in inflammation and cancer Jorge Moscat
11:35:00 “PKCdelta and apoptosis Mary E Reyland
12:10:00 PKCepsilon as a regulator of STAT3 activation in various human cancers Ajit Verma
12:30:00 Lunch
16:00:00 Poster Session 1
18:00:00 Dinner
19:00:00 Oncogenic PKCiota signaling in human lung cancer Alan P Fields
19:35:00 Compartmentalization of Ras signaling Mark R Philips
20:10:00 Break
20:35:00 Novel biochemical and biological effects of DAG analogue signaling through RasGRP pathways James C Stone
21:10:00 Regulation of glioma cell apoptosis and survival by Chaya Brodie
21:45:00 Regulation of beta2-chimaerin by phosphorylation Erin M Griner
22:15:00 PKD3 modulates the proliferation and survival of prostate cancer cells through Akt- and ERK1/2-dependent mechanisms Jane Q Wang
Monday, August 13, 2007
07:30:00 Breakfast
09:00:00 The role of diacylglycerol kinases in T cell fate decisions Gary Koretzky
09:45:00 Termination of diacylglycerol signaling by diacylglycerol kinases Isabel Merida
10:10:00 FASEB Sponsored Coffee Break
10:35:00 Interaction of diacylglycerol kinases with RasGRPs Matt K Topham
11:10:00 Synergy of DGKalpha and zeta in immune cell development, function and tolerance Xiao Ping Zhong
11:25:00 c-Abl, a tyrosine kinase involved in chronic myeloid leukemia, regulates nucleo-cytoplasmic shuttling of DGKα and cell cycle Yasuhito Shirai
12:15:00 Lunch
17:00:00 PI 3-kinase in cancer Lewis Cantley
18:00:00 Dinner
19:00:00 Altered arachidonic acid balance and colon cancer Daniel W Rosenberg
19:35:00 Prostacyclin and thromboxane: novel signaling pathways Emer Smyth
20:10:00 Break
20:35:00 Thromboxane Synthase and TP Receptors In Tumor Progression Kenneth V Honn
21:10:00 Arachidonate-derived signaling lipids Garret A. FitzGerald
Tuesday, August 14, 2007
07:30:00 Breakfast
09:00:00 Phosphoinositide-binding domains: Beyond membrane targeting Mark A Lemmon
09:35:00 Inositol lipid signaling pathways in health and disease Peter Downes
10:10:00 FASEB Sponsored Coffee Break
10:35:00 Cellular targets and activities of the glycerophosphoinositols Daniela Corda
11:10:00 Discovery of novel phosphoinositide binding proteins by genome-wide screening Seth J Field
11:25:00 Oncogenic mutations of the p110a catalytic subunit of PI 3K increase catalytic activity while retaining sensitivity towards PI 3-K inhibitors Claire Chaussade
12:15:00 Lunch
16:00:00 Posters from Day 1 remain on presentation
17:45:00 Poster Prize Award
18:00:00 Dinner
19:00:00 Influence of PTEN gene expression signature on metastasis Ramon E Parsons
19:35:00 Walking the line: PTEN regulation and cancer formation Lloyd C Trotman
20:10:00 Break
20:35:00 Signalling and physiological function of PI 3-kinase isoforms Bart Vanhaesebroeck
21:10:00 Differential regulation of breast cancer cell invasive migration by Akt isoforms Rebecca Chin
Wednesday, August 15, 2007
07:30:00 Breakfast
09:00:00 Receptor-dependent signaling of sphingosine 1-phosphate Tim Hla
09:35:00 A novel mechanism of PAI-1 activation by EGF involving cSrc, PKCδ, and sphingosine kinase 1 important for glioblastoma invasion Tomasz K Kordula
10:10:00 FASEB Sponsored Coffee Break
10:35:00 Cooperative interaction of vascular and stem cell damage Richard Kolesnick
11:10:00 Glucosylceramide synthase: a key metabolic enzyme in apoptosis and cancer Myles Cabot
12:15:00 Lunch
18:00:00 Dinner
19:00:00 Proteomic mapping of caveolae signaling in vascular endothelium for targeted therapy Jan E Schnitzer
19:35:00 Cholesterol-dependent clustering of the EGF receptor investigated in live cells by fluorescence intensity distribution analysis Linda J Pike
20:10:00 Break
20:35:00 Vesicle-binding BAR adapter protein Bin1 in anticancer signaling, survival, and immune escape George C Prendergast
Thursday, August 16, 2007
12:00:00 Departure
3D Tissue Models
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