Track 3: Fourth Annual Ion Channels as Therapeutic Targets
Intercontinental Hotel Boston Massachusetts
Track 3: Fourth Annual Ion Channels as Therapeutic Targets
Cambridge Healthtech Institute 

Schedule of Presentations:

Monday, November 2, 2009
07:00:00 Registration and Morning Coffee
08:30:00 Chairperson’s Opening Remarks
08:40:00 The Challenges of Targeting Ion Channels for Therapeutic Benefit Gregory J. Kaczorowski
09:10:00 Lead Generation and Postdocs in the Pharmaceutical Industry – Lessons Learned Michael Dabrowski
09:40:00 Ion Channel Drug Targets David E. Clapham
10:10:00 Grand Opening Coffee Break in the Exhibit Hall
10:15:00 Structural Studies
10:40:00 Expression and Purification of Human TRPV1 for Structural Studies Alla Korepanova
11:10:00 Structural Insights into the Function of TRPV Channels Rachelle Gaudet
11:15:00 Improving Lead Generation
11:40:00 Negotiation of HERG Liabilities via a 3D in silico Model: A Case Study Mark Slack
12:10:00 Hits Validation Using Endogenous Ion Channels Expressed on Human CD4+ T Cells Melisa Ho
12:40:00 Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own
12:45:00 Ion Channel Cardiac Safety
14:20:00 Chairperson’s Remarks
14:25:00 Cardiovascular Arrhythmia Safety in Drug Development, Inhibition of the Late Ina Current to Stabilize Ventricular Repolarization, and Late Ina as a Therapeutic Target Philip Sager
14:30:00 Emerging Therapeutic Targets
15:25:00 Title to be Announced Derek J. Trezise
15:55:00 Networking Refreshment Break in the Exhibit Hall
16:30:00 Calcium Channelopathies in Neurological Diseases Philippe Lory
17:00:00 Sponsored Presentation (Opportunity Available)
17:15:00 Ion Channels in Metabolic Diseases Chuan-Chu Chou
17:45:00 Happy Hour in the Exhibit Hall
19:00:00 Close of Day
Tuesday, November 3, 2009
07:30:00 Continental Breakfast Breakout Discussion Sessions
07:35:00 Leading Edge Targets
08:30:00 Chairperson’s Remarks
08:40:00 Target Occupancy Studies - Preclinical Decision-making Data Amenable to Clinical Translation Sarah Grimwood
09:10:00 Evaluation of Available Technologies for Ligand-gated Ion Channel Safety Profiling and Screening Gul Erdemli
09:40:00 Networking Coffee Break in the Exhibit Hall
10:40:00 CRAC Channels in Lymphocyte Function: Lessons from STIM1 and ORAI1 Deficient Human Patients and Mice Stefan Feske
11:10:00 Perspectives on TRPA1 as a Pain Target: Challenges and Progress Regina Reilley
11:40:00 Chloride Channels are Drug Targets Alan S. Verkman
12:10:00 Ion Channels as Mediators of Urinary Bladder Overactivity Kevin S. Thorneloe
12:40:00 Close of Conference
3D Tissue Models
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