Sheraton Philadelphia City Center Hotel
17th & Race Street
Philadelphia, PA

Schedule of Presentations:

Thursday, October 1, 2009
13:10:00 Session 1: Esophageal Cancer
13:15:00 Introduction and ISGIO Presidential Inauguration J F Marshall
13:20:00 Welcome Remarks by the President
13:25:00 Increasing Importance of Esophageal Cancer: Epidemiology and Combined Modality Approaches David H. Ilson
13:40:00 Q and A
13:45:00 Sparing Esophagus in Patients with Esophageal Cancer Nabil Rizk
14:00:00 Q and A
14:05:00 Case Presentations:
14:05:00 Case Presentation 1: Locally Advanced Esophageal Cancer Jaffer A. Ajani
14:15:00 Case Presentation 2: EMR Before or After Radiation Hiroya Takiuchi
14:20:00 Case Presentation 3: Barrett’s Dysplasia Treated with an Ablative Approach Lopa Mishra
14:25:00 Break
14:35:00 Hedgehog Signaling - Gli2 and Its Influence in Squamous Esophageal Cancer
14:35:00 Proffered Papers
14:40:00 Neoadjuvant Paclitaxel Poliglumex (PPX), Cisplatin, and Radiation (RT) for Esophageal Cancer
15:05:00 Panel Discussion With Interactive Q/A Nabil Rizk
15:05:00 Safety of Minimally Invasive Esophagectomy (MIE) After Neoadjuvant Chemoradiotherapy and as Primary Resection at a Non- University Tertiary Care Center (NUTCC)
15:10:00 Metastatic Pancreatic Cancer: How to Select the Best Options Malcolm J Moore
15:10:00 Session 2: Pancreatic Cancer
15:25:00 Q and A
15:30:00 Neuroendocrine Tumors of the Pancreas: An Update Mary Mulcahy
15:45:00 Q and A
15:50:00 Case Discussions: Localized and Metastatic Pancreatic Cancer
15:55:00 Case Presentation 1: Metastatic Second-Line Philip Agop Philip
16:10:00 Systemic Delivery of Liposome-Incorporated Adrenomedullin Receptor (ADMR) Small Interfering RNA Against Tumor and Its Microenvironment Reduced Pancreatic Tumor Growth
16:10:00 A Novel Small Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In Vivo Sushovan Guha
16:10:00 Case Presentation 2: Locally Advanced (Radiotherapy vs. Chemotherapy) Gauri Varadhachary
16:10:00 Proffered Papers
16:15:00 Phase II Study of Imatinib Mesylate and Gemcitabine for First-line Treatment of Metastatic Pancreatic Cancer Richard Moss
16:40:00 Panel Discussion With Interactive Q/A Sushovan Guha
17:00:00 Defining the Contributions of Targeted Therapy in Colorectal Cancer2
19:10:00 You Treat My Patients: An ISGIO Teaching Course for Fellows and Junior Practitioners Presidential Session
19:15:00 Case Presentations Jaffer A. Ajani
19:25:00 Rectal cancer (localized disease- preoperative and postoperative situation)
19:30:00 Metastatic colon cancer (front-line, second-line and third-line therapy, and potentially curable disease)
19:35:00 Pancreatic cancer (localized resectable, borderline resectable, and unresectable]
19:40:00 Gastric cancer (localized [preoperative and postoperative therapy] and metastatic [front-line, second-line therapy]
19:40:00 Esophageal cancer (localized squamous and adenocarcinoma, high-grade dysplasia in Barrett’s) esophagus
19:45:00 Anal cancer (one case)
19:50:00 Hepatocellular (localized, unresectable, second-line therapy)
20:00:00 Gall bladder cancer (resected T3 N1) Jaffer A. Ajani
20:05:00 Panelists: Al B. Benson, Bert O'Neil, John Marshall
Friday, October 2, 2009
07:45:00 Session 3: Advanced Colorectal Cancer J F Marshall, Brendan O’Neill
08:00:00 Treatment of Incurable Metatstatic Colorectal Cancer Leonard Saltz
08:15:00 Q and A
08:20:00 Curable Metastatic Colorectal Cancer Howard S. Hochster
08:35:00 Q and A
08:40:00 Case Presentations:
09:00:00 Case Presentation 1: First-Line Advanced John Marshall
09:20:00 Case Presentation 2: Metastatic But Potentially Curable Axel Grothey
09:30:00 Case Presentation 3: Second-Line and Third-Line Brendan O’Neill
09:40:00 Proffered Papers
09:45:00 Randomized Phase 3 Study of Panitumumab With FOLFOX4 Compared to FOLFOX4 Alone as 1st-line Treatment for Metastatic Colorectal Cancer: The PRIME Trial Jean-Yves Douillard
09:50:00 Randomized Phase 3 Study of Panitumumab With FOLFIRI vs. FOLFIRI Alone as Second‑Line Treatment in Patients With Metastatic Colorectal Cancer Michel Ducreux
10:05:00 Baseline Quality of Life Is a Strong and Independent Prognostic Factor for Overall Survival in Metastatic Colorectal Cancer
10:10:00 Panel Discussion With Interactive Q/A Howard S. Hochster, Daniel Haller, Yasuhide Yamada, Michael Choti, Bert O'Neil, Axel Grothey, John Marshall, Leonard Saltz, Hiroya Takiuchi
11:00:00 Expanding the Role of TKIs in the Treatment of GIST3
13:00:00 Session 4: Hepatobiliary Cancer Michael Choti, Melanie Thomas
13:15:00 Case Presentations:
13:20:00 Case Presentation 1: Localized Hepatocellular Carcinoma: Resection, Ablation, or Transplantation? Michel Ducreux
13:30:00 Case Presentation 2: Patient Who Had A Bile Duct Cancer Michael Choti
13:45:00 Case Presentation 3: Patient Treated with TACE but where are the data? Melanie Thomas
13:55:00 Radiation Therapy for Intrahepatic Cholangiocarcinoma Nadia S.K. Haque
13:55:00 Proffered Papers
14:15:00 Association of Gallbladder Polyp Size With Obesity and With Malignant Potential
14:20:00 Post-Transplant Recurrence of Hepatocellular Carcinoma and Elevated NLR
14:25:00 Break
14:30:00 Keynote Presentation: Oncogenes and Cancer Nita Ahuja
14:30:00 Session 5: Emerging Science Lopa Mishra
14:55:00 Q and A
15:05:00 Cancer Stem Cells: Cancer Initiation, Therapy Resistance and Metastases Lopa Mishra
15:20:00 Q and A
15:25:00 Signaling Pathways of Survival- What Can They Teach Us? Peter K Vogt
15:40:00 Q and A
15:45:00 Panel Discussion With Interactive Q/A Peter K Vogt, Lopa Mishra, Nita Ahuja, Sushovan Guha
16:00:00 Session 6: Adjuvant Colon Cancer
16:15:00 Biomarker Signatures that Predict Benefit From Therapy Norman Wolmark
16:30:00 Q and A
16:35:00 Case Presentations:
16:35:00 Case Presentation 1: Stage II David Ryan
16:45:00 Case Presentation 2: Stage III John Marshall
17:00:00 Case Presentation 3: Stage Iva After Primary Surgery for Synchronous Liver Metastases- Previously Untreated Axel Grothey
17:05:00 Fiber as Protective Factor for Colon Polyps
17:05:00 Proffered Paper
Saturday, October 3, 2009
07:00:00 Session 7: Gastric Cancer
08:00:00 Molecular Biology: East and West Ju-Seog Lee
08:15:00 Gastric Cancer Surgery: East and West Sung Hoon Noh
08:30:00 Localized Gastric Cancer: East and West Which is the Best Approach? Yung Jue BANG
08:45:00 Q and A
08:50:00 Case Presentations:
08:55:00 Case Presentation 1: Preoperative Therapy Weijing Sun
09:00:00 Case Presentation 2: Metastatic First-Line Lin Shen
09:05:00 Case Presentation 3: Chemoradiation as Adjuvant Therapy Gary Yang
09:15:00 Advanced Gastric Cancer: An Update Al B. Benson III
09:30:00 Q and A
09:35:00 Effects of Genetic Polymorphisms of Thymidylate Synthase (TS) and Methylenetetrahydrofolate Reductase (MTHFR) Along With Folate Intake on Clinical Outcome of Gastric Cancer Patients Treated With Fluorouracil-Based Chemotherapy
09:35:00 Proffered Papers
09:45:00 Prognostic Value of Preoperative Clinical Staging Assessed by Computed Tomography in Resectable Gastric Cancer Patients: a Viewpoint in the Era of Preoperative Treatment
09:50:00 Phase II Study of Weekly Paclitaxel as Third-Line Chemotherapy for Advanced or Recurrent Gastric Cancer (OGSG0602)
10:00:00 Liposome-Formulated siRNA Against Msi1 and Docetaxel Treatment in an Animal Model of Advanced Gastric Adenocarcinoma Eradicates Cancer Stem Cells and Metastasis
10:15:00 Panel Discussion With Interactive Q/A Moderator: TBD Jaffer A. Ajani, Yung Jue BANG, Al B. Benson, Lin Shen, Weijing Sun, Gary Yang, Ju-Seog Lee, Sung Hoon Noh
10:30:00 Session 8: Rectal Cancer Lisa A. Kachnic, Mary Mulcahy
10:35:00 Prognostic Factors of Rectal and Anal Cancer Outcomes Prajnan Das
10:50:00 Q and A
10:55:00 Current Approaches to Localized Rectal Cancer- T1 T2 Lesions and the Trans-Anal Approach Lisa A. Kachnic
11:10:00 Q and A
11:15:00 Case Presentations:
11:15:00 Case Presentation 1: Preoperative Chemoradiation Al B. Benson
11:20:00 Case Presentation 2: Postoperative Chemoradiation Daniel Haller
11:30:00 Case Presentation 3: Radiation is Not Necessary in this Case Mary Mulcahy
11:45:00 Q and A
11:50:00 Proffered Paper
11:50:00 Low Lying Rectal Cancer With Anal Canal Involvement: Abdominoperineal or Low Anterior Resection After Neoadjuvant Chemoradiotherapy
12:00:00 Panel Discussion With Interactive Q/A Lisa A. Kachnic, Daniel Haller, Yixing Jiang, Mary Mulcahy, Al B. Benson
12:15:00 Mentoring Junior Faculty: Is It a Two-Way Street? Ruth He, Lopa Mishra
12:30:00 Summary
12:30:00 Announcements Jaffer A. Ajani
13:00:00 2Supported by an educational grant from Genentech BioOncology
13:05:00 3Supported by an educational grant from Novartis
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