Second Annual Ion Channels: An Emerging Target for Therapeutic Development Oct (17-18)
World Trade Center
200 Seaport Boulevard
Boston, MA
Second Annual Ion Channels: An Emerging Target for Therapeutic Development 
Discovery on Target

Schedule of Presentations:

Wednesday, October 17, 2007
07:30:00 Registration Opens (07:30-14:10)
14:10:00 POTASSIUM CHANNELS AND DISEASE (14:10-15:45) James Herrington, Christine Beeton, Chuan-Chu Chou, Jesus Tito Gonzalez
14:10:00 POTASSIUM CHANNELS AND DISEASE: Chairperson’s Remarks (14:10-14:15) Jesus Tito Gonzalez
14:15:00 POTASSIUM CHANNELS AND DISEASE: An Emerging Target for Several Major Diseases of Unmet Medical Needs (14:15-14:45) Chuan-Chu Chou
14:45:00 POTASSIUM CHANNELS AND DISEASE: Kv1.3 Channels: Therapeutic Target for T-cell-mediated Autoimmune Diseases (14:45-15:15) Christine Beeton
15:15:00 POTASSIUM CHANNELS AND DISEASE: Potassium Channels of the Pancreatic Beta-cell and Their Regulation of Insulin Secretion (15:15-15:45) James Herrington
15:45:00 TARGETING NEUROPSYCHIATRIC DISORDERS: Exploring Positive Allosteric Modulators of the Alpha7 Nicotinic Receptor (15:45-16:15) John Dunlop
15:45:00 TARGETING NEUROPSYCHIATRIC DISORDERS (15:45-18:20) Zhigang Xiong, Daniel W. Beacham, Ronald G. Lafreniere, John Dunlop
16:15:00 TARGETING NEUROPSYCHIATRIC DISORDERS: Networking Refreshment Break in the Exhibit Hall (16:15-16:50)
16:50:00 TARGETING NEUROPSYCHIATRIC DISORDERS: Technology Watch; Bringing Potassium Flux Assays to a Higher (Throughput) Level: Fluorescent FluxOR™ Detection Meets BacMam Ion Channel Delivery (16:50-17:05) Daniel W. Beacham
17:05:00 TARGETING NEUROPSYCHIATRIC DISORDERS: Technology Watch (17:05-17:20)
17:20:00 TARGETING NEUROPSYCHIATRIC DISORDERS: Search for New Drug Targets for Episodic Neurological Disorders through Mutation Screen of 150 Human Ion Channel Genes (17:20-17:50) Ronald G. Lafreniere
17:50:00 TARGETING NEUROPSYCHIATRIC DISORDERS: Acid-sensing Ion Channels as Novel Therapeutic Targets for Neurological Disorders (17:50-18:20) Zhigang Xiong
18:20:00 End of Conference Day
Thursday, October 18, 2007
07:30:00 Registration Open (07:30-15:40)
08:35:00 CRAC – AN EMERGING TARGET: Chairperson’s Remarks (08:35-08:40) Martin Gosling
08:35:00 CRAC – AN EMERGING TARGET (08:35-09:40) Murali Prakriya, Martin Gosling, Gonul Velicelebi
08:35:00 CRAC – AN EMERGING TARGET: CRAC Channel Inhibition A Novel Strategy for Immunomodulation (08:35-08:40) Gonul Velicelebi
09:10:00 CRAC – AN EMERGING TARGET: Targeting the CRAC Channel for Drug Discovery: Biophysical and Pharmacological Considerations (09:10-09:40) Murali Prakriya
09:40:00 TECHNOLOGIES FOR ION CHANNEL DRUG DISCOVERY (09:40-12:25) Jesus Tito Gonzalez, Martin Gosling, Mads P.G. Korsgaard, Derek J. Trezise
10:10:00 TECHNOLOGIES FOR ION CHANNEL DRUG DISCOVERY: Networking Coffee Break in the Exhibit Hall (10:10-10:55)
10:55:00 TECHNOLOGIES FOR ION CHANNEL DRUG DISCOVERY: Novel Applications of Planar Array Electrophysiology in Ion Channel Drug Discovery (10:55-11:25) Derek J. Trezise
11:25:00 TECHNOLOGIES FOR ION CHANNEL DRUG DISCOVERY: Probing Voltage-gated Channels in Neurons (11:25-11:55) Jesus Tito Gonzalez
11:55:00 TECHNOLOGIES FOR ION CHANNEL DRUG DISCOVERY: Primary Screening on the hERG Channel Using Automated Patch Clamp (11:55-12:25) Mads P.G. Korsgaard
12:00:00 TECHNOLOGIES FOR ION CHANNEL DRUG DISCOVERY: Screening Ion Channel Targets with Therapeutic Potential in Respiratory Disease: Application of Automated Electrophysiology (09:40-12:25) Martin Gosling
12:25:00 TECHNOLOGIES FOR ION CHANNEL DRUG DISCOVERY: Luncheon Workshop (Sponsorship Available) or Lunch on Your Own (12:25-12:55)
12:55:00 Session Break (12:55-13:55)
13:55:00 TARGETING PAIN MANAGEMENT: Chairperson’s Remarks (13:55-14:00) Iain Chessell
13:55:00 TARGETING PAIN MANAGEMENT (13:55-17:10) Arthur Gomtsyan, Roland Kozlowski, Bruce Clapham, Douglas S. Krafte, Iain Chessell
14:00:00 TARGETING PAIN MANAGEMENT: Novel and Translatable Mechanisms for Pain Treatment - Lessons From the P2X Receptor Family (14:00-14:30) Iain Chessell
14:30:00 TARGETING PAIN MANAGEMENT: TRP Channels as Drug Targets (14:30-15:00) David E. Clapham
15:00:00 TARGETING PAIN MANAGEMENT: Networking Refreshment Break in the Exhibit Hall (15:00-15:40)
15:40:00 TARGETING PAIN MANAGEMENT: Identification and Characterisation of Novel Small Molecule Inhibitors of the Kv1.x/KvβChannel Subunit Interactions for Pain Management (15:40-16:10) Roland Kozlowski
16:10:00 TARGETING PAIN MANAGEMENT: Role of Nav1.8 in Chronic Pain States (16:10-16:40) Douglas S. Krafte
16:40:00 TARGETING PAIN MANAGEMENT: Potent and Selective TRPV1 Antagonist for Pain Management (16:40-17:10) Arthur Gomtsyan
17:10:00 Close of Ion Channels Conference
3D Tissue Models
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