LYMPHOCYTES AND THE IMMUNE SYSTEM: Molecular, Cellular and Integrative Mechanisms
Hilton Tucson El Conquistador Golf and Tennis Resort
Arizona, mm
Transcriptional and Microenviromental Regulation of Lymphocyte Cell Fate Decisions
Antigen receptor gene assembly and transcriptional
DNA rearrangements and the germinal center reaction
Lymphocyte activation
Lymphocyte homeostasis

Schedule of Presentations:

Saturday, July 7, 2007
16:00:00 Conference Registration
18:00:00 FASEB Opening Reception
19:00:00 Dinner
20:45:00 Keynote address
Sunday, July 8, 2007
07:30:00 Breakfast
12:00:00 Lunch
13:00:00 Role of notch-fringe interactions in lymphocyte development and homeostasis
13:30:00 Transcriptional regulation of lymphocyte lineage commitment Stephen Nutt
14:00:00 Group photo and FASEB Sponsored Coffee Break
14:35:00 Transcriptional regulation of CD4/CD8 lineage commitment by ThPOK Dietmar Kappes
15:10:00 Ablation of ribosomal protein L22 selectively impa irs alphabeta T cell development by activation of a p53-dependent checkpoint David Wiest
15:40:00 T Cell development: exit strategies Kris Hogquist
16:10:00 Poster Session
18:00:00 Dinner
19:00:00 Targeting V(D)J recombination through promoter activation and germline transcription Ranjan Sen
19:30:00 Role and regulation of antisense intergenic transcription in V(D)J recombination” Anne Corcoran
20:00:00 Transcriptional timing of V(D)J recombination
20:30:00 Break
20:45:00 Targeting and mistargeting of the V(D)J recombinase Mark Schlissel
21:15:00 Cellular responses to RAG-induced DNA double strand breaks Barry Sleckman
Monday, July 9, 2007
07:30:00 Breakfast
09:00:00 Workshop 1
12:00:00 Lunch
13:00:00 Molecular studies of class switch recombination Amy Kenter
13:30:00 Mechanisms of Class Switch Recombination and of NHEJ Michael R Lieber
14:00:00 Allelic choice governs somatic hypermutation at the Igk locus in vivo Yehudit Bergman
14:30:00 FASEB Sponsored Coffee Break
14:50:00 AID domains defined from functional analyses using AID mutants Reiko Shinkura
15:20:00 Defining the genetic program that controls the formation of B-cell memory David Tarlinton
15:50:00 Discussion
16:00:00 Poster Session
18:00:00 Dinner
19:00:00 Signaling and the immunological synapse: a view from the center Avi Kupfer
19:30:00 Integration of T cell signals: lessons from primary immunodeficiencies Pam Schwartzberg
20:00:00 Action mechanisms of adaptor molecules in B lymphocytes” Tomohiro Kurosaki
20:30:00 Break
20:45:00 Mutual antagonism of TFII-I and PLC γ in the regulation of calcium entry Stephen Desiderio
21:15:00 Regulation of B lymphopoiesis by EBF proteins Rudolf Grosschedl
Tuesday, July 10, 2007
07:30:00 Breakfast
09:00:00 Workshop 2
12:00:00 Lunch
13:00:00 Feedback loops regulating T cell responses Rose Zamoyska
13:30:00 BCR signaling provides NF-kB2 substrate (p100) for BLyS mediated survival Michael Cancro
14:00:00 Receptor editing David Nemazee
14:30:00 FASEB Sponsored Coffee Break
14:50:00 Generating functional CD8 memory Michael Bevan
15:20:00 Dissecting the genetic program of CD8 + T cell memory Stephen P. Schoenberger
15:50:00 Discussion
18:00:00 Dinner
19:00:00 Development of NK Cells
19:30:00 Antibodies and their receptors: coupling innate and adaptive immunity Rene Ott
20:00:00 Break
20:15:00 Gene regulation logic in activated macrophages Stephen Smale
20:45:00 Asymmetric Division of a T Lymphocyte in the Initiation of Adaptive Immunity Steven L. Reiner
21:15:00 Short talks
Wednesday, July 11, 2007
07:30:00 Breakfast
12:00:00 Lunch
13:00:00 Regulation of Lymphocyte Egress by Innate and Adaptive Immune Responses Mehrdad Matloubian
13:30:00 Germinal center B cell migration patterns defined by intravital multiphoton microscopy Ann Haberman
14:00:00 FASEB Sponsored Coffee Break
14:20:00 Regulation of homeostatic chemokine expression and cell trafficking during immune responses Scott Mueller
14:50:00 Leukocyte recruitement in vivo: Multiple organs, multiple mechanisms Paul Kubes
15:20:00 Multiple points of regulation of thymic development by the adaptor protein ShcA” Kodi Ravichandran
15:50:00 Discussion
18:00:00 Dinner
19:00:00 Analyzing the architectures of gene regulatory networks underlying the development and differentiation of Harinder Singh
19:30:00 The TCR/CD3 complex: information transfer in six and a half seconds Michael Kuhns
20:00:00 Break
20:20:00 Signaling specificity and crosstalk via the NF-_B Signaling System Alex Hoffmann
20:50:00 Intravital imaging of immune cell trafficking: control of lymphocyte migration by chemical and physical signals Marc Bajenoff
21:20:00 Discussion
Thursday, July 12, 2007
07:30:00 Breakfast
09:00:00 Defects in Early B Cell Development Mary Ellen Conley
09:00:00 Defects in Early B Cell Development Mary Ellen Conley
09:30:00 Devising a method to generate human antigen-specificBCR+B cell clones in vitro Hergen Spits
10:00:00 FASEB Sponsored Coffee Break
10:20:00 Germline N-Ras mutation causes a human lymphoproliferative syndrome Michael J. Lenardo
10:30:00 Box Lunches Available
10:50:00 The early antibody-secreting cell response to influenza booster in humans Patrick Wilson
11:20:00 Discussion
3D Tissue Models
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