The International Quantitative Imaging Cytometry Centers of Excellence Provide a Forum for Educational and Training Programs in Quantitative Imaging Cytometry, with a Specific Focus on Solid-Phase Laser Scanning Imaging Cytometry

Boston, Massachusetts


   Children’s Hospital Boston, Massachusetts August 10–12, 2010

   The International Quantitative Imaging Cytometry Centers of Excellence
   provide a forum for educational and training programs in quantitative
   imaging cytometry, with a specific focus on solid-phase laser scanning
   imaging cytometry.

   Tuesday, August 10

   Quantitative imaging cytometry as a cutting-edge research tool

   Chair: William Telford, NIH , Bethesda, MD

   Imaging cytometry: An expanding role in biomedical imaging analysis.
   William Telford, National Cancer Institute NIH , Bethesda, MD

   Spatial analysis of hematopoietic stem and progenitor cells in bone
   marrow. Leslie Silberstein, Children’s Hospital, Dana-Farber Cancer
   Institute, Brigham and Women’s Hospital, Harvard Medical School,
   Boston, MA

   Combinatorial development of biomaterials for tissue engineering and
   drug delivery. Daniel Anderson, David H. Koch Institute for
   Integrative Cancer Research, Massachusetts Institute of Technology,
   Cambridge, MA

   The iCys® imaging cytometer in the epigenetic toolbox for autism
   research. Janine LaSalle, UC Davis School of Medicine, Davis, CA

   Wednesday, August 11

   Advanced cell cycle and DNA damage analysis

   Chair: Michael Fenech, CSIRO , Australia

   Assessment of DNA damage by high-resolution cytometry. Zbigniew
   Darzynkiewicz, Brander Cancer Research Institute, Valhalla, NY

   Advanced cell cycle analysis. James Jacobberger, Case Western Reserve
   University, Case Comprehensive Cancer Center, Cleveland, OH

   The untapped potential of laser scanning cytometry in genome damage,
   proteome and nutritional diagnostics at the single cell and sub-type
   level. Michael Fenech, CSIRO Food and Nutrition Sciences, Commonwealth
   Scientifi c and Industrial Research Organisation, Adelaide, Australia

   Potential mechanisms for the generation of chromosome aneuploidy in
   human cancer. John M. Lehman, Brody School of Medicine, East Carolina
   University, Greenville, NC

   Thursday, August 12

   Pharmacodynamic and diagnostic tissue-based biomarkers

   Chair: Shazib Pervaiz, NUS and Duke- NUS GMS , Singapore

   Application of imaging cytometry to the molecular therapeutics of
   human solid tumors. David Hedley, Ontario Cancer Institute, University
   Health Network, Toronto, ON, Canada

   Leveraging quantitative imaging cytometry to measure the
   pharmacodynamic impact of drugs in development. Gloria Juan, Amgen,
   Thousand Oaks, CA

   Quantitative imaging cytometry for the diagnostic pathologist: What
   does the laser scatter imaging component add? William Geddie,
   University Health Network/Toronto General Hospital, Toronto, ON,

   Mislocalization of APAFI as a novel diagnostic and prognostic marker
   for refractory diffuse B-cell lymphoma? Shazib Pervaiz, National
   University of Singapore and Duke- NUS GMS

   Capturing signaling events in the immune system in situ. Margaret
   Harnett, University of Glasgow, Scotland, UK

   Short talks chosen from submitted abstracts will be presented each

   Afternoon Workshops:

   Workshop I Cytome diagnostics workshop
   Michael Fenech, CSIRO Food and Nutrition Sciences, Adelaide, Australia

   Workshop II Automated quantitative analysis of protein expression in
   David Krull, GlaxoSmithKline, Research Triangle Park, NC

   Workshop III Advanced cell cycle analysis
   James Jacobberger and Tammy Stefan, Case Comprehensive Cancer Center,
   Cleveland, OH

   Workshop IV Immunophenotyping in FNAs (fine needle aspirates)
   William Geddie, University Health Network/Toronto General Hospital,
   Toronto, ON, Canada

   Workshop V Analysis of drug-induced DNA damage
   Shazib Pervaiz, National University of Singapore and Duke- NUS GMS and
   Soo-Fern Lee, National University of Singapore

   Workshop VI Quantitative imaging of bone marrow microenvironment
   César Nombela-Arrieta and Shin-Young Park, Children’s Hospital Boston

   Registration is open at:

   • Registration for full program ends: July 10, 2010.
   • Registration for morning lectures only ends: August 5, 2010.
   • Call for short oral and poster presentations: Submission deadlines
   March 10 and June 10, 2010 respectively.

Event Sponsors

Schedule of Presentations:

Tuesday, August 10, 2010
09:05:00 Quantitative Imaging Cytometry as a Cutting-Edge Research Tool | Enders Auditorium, Children's Hospital Boston
09:10:00 Welcome Leslie Silberstein
10:00:00 Imaging Cytometry: An Expanding Role in Biomedical Imaging Analysis William Telford
11:00:00 Spatial Analysis of Hematopoietic Stem and Progenitor Cells in Bone Marrow Leslie Silberstein
11:30:00 Combinatorial Development of Biomaterials for Tissue Engineering and Drug Delivery Daniel G Anderson
12:00:00 The iCys® Imaging Cytometer in the Epigenetic Toolbox for Autism Research Janine M LaSalle
12:30:00 Selected Short Oral Presentation
Wednesday, August 11, 2010
09:00:00 Advanced Cell Cycle and DNA Damage Analysis | Jimmy Fund Auditorium, Dana-Farber Cancer Center
09:05:00 Assessment of DNA Damage by High-Resolution Cytometry Zbigniew Darzynkiewicz
10:00:00 Advanced Cell Cycle Analysis James Jacobberger
11:00:00 The Untapped Potential of Laser Scanning Cytometry in Genome Damage, Proteome and Nutritional Diagnostics at the Single Cell and Sub-Type Level Michael Fenech
11:30:00 Potential Mechanisms for the Generation of Chromosome Aneuploidy in Human Cancer John M. Lehman
12:00:00 Selected Short Oral Presentation
Thursday, August 12, 2010
09:00:00 Pharmacodynamic and Diagnostic Tissue-Based Biomarkers | Jimmy Fund Auditorium, Dana-Farber Cancer Center
09:05:00 Application of Imaging Cytometry to the Molecular Therapeutics of Human Solid Tumors David W. Hedley
10:00:00 Leveraging Quantitative Imaging Cytometry to Measure the Pharmacodynamic Impact of Drugs in Development Gloria Juan
11:00:00 Quantitative Imaging Cytometry for the Diagnostic Pathologist: What Does the Laser Scatter Imaging Component Add? William Geddie
11:30:00 Mislocation of APAFI as a Novel Diagnostic and Prognostic Marker for Refractory Diffuse B-Cell Lymphoma? Shazib Pervaiz
12:00:00 Capturing Signaling Events in the Immune System in Situ Margaret Harnett
12:30:00 Selected Short Oral Presentation
14:00:00 AFTERNOON WORKSHOPS | choice of three of the workshops
14:05:00 Workshop I | Cytome Diagnostics Wayne Leifert, Maxime Francois
14:10:00 Workshop II | Quantitative Assessment of Pancreatic Islets David Krull
14:15:00 Workshop III | Advanced Cell Cycle Analysis Tammy Stefan, James Jacobberger
14:20:00 Workshop IV | Immunophenotyping in FNAs (fine needle aspirates) William Geddie
14:25:00 Workshop V | Analysis of Drug-Induced DNA Damage A Holmes, Shazib Pervaiz
14:30:00 Workshop VI | Quantitative Imaging of Bone Marrow Microenvironment Shin-Young Park, César Nombela-Arrieta
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