Cancer Pharmacogenetics: Personalising Medicine
CNIO Auditorium
Melchor Fernández Almagro 3, 28029 Madrid, Spain
Madrid, Spain


   The Spanish National Cancer Research Centre ( CNIO ) announces its
   2010 CNIO Frontiers Meetings:

   22 - 24 November 2010
   Application deadline: October 15, 2010

   Cancer Pharmacogenetics: Personalising Medicine

   Javier Benítez
   CNIO , Madrid, Spain

   William E. Evans
   St. Jude Children’s Research Hospital, Memphis, USA

   Magnus Ingelman-Sundberg
   Karolinska Institutet, Stockholm, Sweden

   Miguel Martín
   Hospital Gregorio Marañón, Madrid, Spain

   For further information and to apply please go to

   Centro Nacional de Investigaciones Oncológicas ( CNIO )

   Melchor Fernández Almagro, 3 | 28029 Madrid | Spain

Schedule of Presentations:

Monday, November 22, 2010
09:15:00 Welcome address Javier Benitez
09:25:00 Session I: Inherited and somatic genetic variation and cancer pharmacotherapy Rafael Rosell
09:30:00 Pharmacogenetics and epigenetics of drug response Magnus Ingelman-Sundberg
10:05:00 Role of Polymorphic Transporters in Taxane Pharmacodynamics Alex Sparreboom
10:40:00 Topic: Pharmacodynamics Julian Downward
11:15:00 Coffee break and poster session
11:45:00 Inter‐individual and inter‐ethnic variation in the transcriptional response to glucocorticoids Anna Di Rienzo
12:20:00 Topic: The International Cancer Genome Consortium Peter Campbell
12:55:00 Short talk #1
13:10:00 Short talk #2
13:30:00 Lunch and poster session
14:55:00 Session II: Pharmacogenomic and epigenomic determinants of anti‐cancer drug efficacy
15:00:00 Breast cancer: tamoxifen and aromatase inhibitors David A. Flockhart
15:35:00 Personalizing targeted therapies in lung cancer Rafael Rosell
16:10:00 Coffee break and poster session
16:40:00 Epigenomics and cancer treatment Manel Esteller
17:15:00 Short talk #3
17:30:00 Short talk #4
Tuesday, November 23, 2010
09:25:00 Session III: Pharmacogenetics of cancer adverse effects Miguel Martín
09:30:00 ALL therapy William E Evans
10:05:00 Colorectal cáncer Howard McLeod
10:40:00 Breast cancer Anna González-Neira
11:15:00 Group picture, coffee break and poster session
11:45:00 Identification of genetic variants associated to the adverse effects of microtubule‐targeted anticancer drugs Cristina Rodríguez-Antona
12:20:00 Short talk #5
12:35:00 Short talk #6
13:00:00 Lunch and poster session
14:25:00 Sesion IV: State‐of‐the‐art in high‐throughput technologies and bioinformatic tools for pharmacogenetics Peter Campbell
14:30:00 Functional Genomics and Proteomics in Cancer Research Jörg Hoheisel
15:05:00 From pharmacogenetics to pharmacogenomics, the technological challengeology D Flores Benítez
15:40:00 Bioinformatic tools and in silico predictions Arcadi Navarro
16:15:00 Coffee break and poster session
16:45:00 Pharmacogenetics databases Teri E. Klein
17:20:00 Short talk #7
17:35:00 Short talk #8
Wednesday, November 24, 2010
09:25:00 Session V: Implementing Pharmacogenetics: how industry, regulators, clinicians and policymakers are shaping the field William E Evans
09:30:00 Clinical trials Miguel Martín
10:05:00 Barriers for pharmacogenetics implementation R H N Van Schaik
10:40:00 Drug Discovery Robert Wasserman
11:15:00 Coffee break and poster session
11:45:00 Regulatory agencies Eric Abadie
12:20:00 Closing remarks and poster prize Magnus Ingelman-Sundberg
12:25:00 Note: Talks: 25 minutes Discussion: 10 minutes after each talk
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