Molecular Mechanisms of Neurodegeneration 2007
Jolly Beach Resort, Antigua
Bolans Village
Antigua, West Indies, mm
          o Genetics of neurodegenerative disease
          o APP processing and Abeta
          o Mechanisms of neurodegenerative disease
          o Therapies and diagnostics

Schedule of Presentations:

Monday, December 3, 2007
12:00:00 New Presentation
12:00:00 New Presentation
12:00:00 New Presentation
12:00:00 Registration
12:00:00 New Presentation
12:00:00 New Presentation
18:00:00 Welcome & Introductions
18:15:00 Evening reception and buffet
Tuesday, December 4, 2007
07:30:00 Breakfast
09:00:00 Genetics of Neurodegenerative Disease Rudolph E Tanzi
09:30:00 The Anti-Aging Protein Klotho in Aging and Alzheimer’s Disease Carmela Abraham
09:45:00 The p150 subunit of dynactin (DCTN1) gene in amyotrophic lateral sclerosis Christoph Münch
10:00:00 TBC, Morning Coffee Lars Bertram
11:00:00 Molecular Mechanisms of Amyloid ß-Peptide generation Christian Haas
11:30:00 Presenilin Function and Dysfunction in Alzheimer’s Disease Sam Sisodia
12:00:00 TBC, Lunch, Free time for social events Tae-Wan Kim
17:45:00 Over-expression of ABCA1 in the PDAPP mouse model of Alzheimer’s disease markedly reduces amyloid deposition David Holtzman
18:15:00 TBC Charlie G Glabe
18:45:00 Neurotoxic effects induced by A? peptides derived from the Drosophila Amyloid Precursor Protein (APP) suggest a conserved toxic function of APP proteins
19:00:00 TBC, Poster session and buffet Sam Gandy
19:30:00 Closing
Wednesday, December 5, 2007
07:30:00 Breakfast
09:00:00 Huntington’s Disease: discerning a novel disease initiating mechanism Marcy MacDonald
09:30:00 Cerebral microvascular amyloid promotes localized neuroinflammation, neurodegeneration, and behavioral deficits in a transgenic mouse model Bill Van Nostrand
09:45:00 The role of Cdk5 in neuronal cell cycle control and neurodegeneration
10:00:00 TBC, Morning Coffee
11:00:00 TBC Don W Cleveland
11:30:00 TBC Karen Duff
12:00:00 Neutral endopeptidase-deficient mice show enhanced long-term potentiation in aged hippocampus and amygdala
12:15:00 Novel, small molecule p75ntr ligands prevent Juliet Knowles
12:30:00 Lunch, Free time for social events
16:00:00 Two different acat inhibitors reduce amyloid pathology in vivo Dora Kovacs
16:30:00 TBC Steve Wagner
17:00:00 Alzheimer’s disease: Aβ-amyloid as the principal molecular and therapeutic diagnostic target Colin Masters
17:30:00 Poster session and drinks
19:30:00 Beach barbeque
Thursday, December 6, 2007
09:00:00 Immunotherapy of alzheimer’s disease Roger Nitsch
09:30:00 Recombinant human erythropoietin for the treatment of the neurodegenerative disease Friedreich`s ataxia Barbara Scheiber Mojdehkar
09:45:00 AD-Immunotherapy: DNA Vaccines, Adjuvants and Animal Models
10:00:00 Active Amyloid-Beta (Aß) Immunization Stabilizes or Improves Cognition in Aged Caribbean Vervets Cynthia A Lemere
11:30:00 David Holtzman David Holtzman
12:00:00 Lunch and departures Charlie G Glabe
3D Tissue Models
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