Ninth Annual International Conference on Frontiers in Cancer Prevention Research
Pennsylvania Convention Center
connected to the Philadelphia Marriott Downtown Hotel
Philadelphia, Pennsylvania


   American Association for Cancer Research

   Upcoming Conferences at the Forefront of Cancer Research

   November 7-10, 2010

   Ninth Annual International Conference on Frontiers in Cancer
   Prevention Research

   Chairperson: Eva Szabo Philadelphia, PA

   Please visit often for additional
   conferences and program updates.

Schedule of Presentations:

Sunday, November 7, 2010
10:00:00 Educational Sessions 1: Metabolomics: An Emerging Tool for Defining Complex Biological Systems in Health and Disease Steven S. Gross
10:05:00 Untargeted plasma metabolite profiling: Strategies and approaches for comprehensive characterization of gene mutations and drug actions Steven S. Gross
10:15:00 Metabolomics of disease progression Christopher Beecher
10:30:00 Metabolomics as a unique biochemical approach for therapeutic discovery Gary Siuzdak
10:45:00 Educational Sessions-2 : Trends in Epidemiology Research Gloria M. Petersen
10:50:00 Introduction Gloria M. Petersen
11:00:00 Gene, environment, and risk factor interaction in pancreatic cancer Harvey A Risch
11:10:00 Genomic technologies for variant detection: Current and future trends John D Carpten
11:20:00 Molecular genetic research: Translating discovery into risk assessment and genetic testing Gloria M. Petersen
11:30:00 Professional Advancement Session Margaret R. Spitz
11:35:00 Lunch on own
13:00:00 Educational Session- 3 : Epigenetics Ari M. Melnick
13:05:00 The epigenomic programming of cancer cells Ari M. Melnick
13:15:00 DNA methylation, its role in cancer development, and its use as a biomarker James G. Herman
13:30:00 Histone modifying enzymes, their role in cancer, and their therapeutic targeting Kapil N. Bhalla
13:40:00 Educational Session-4 : Team Science and Transdisciplinary Approaches to Cancer Prevention Research Within and Across Institutions Sarah Gehlert
13:45:00 Fostering team science and transdisciplinary approaches to cancer prevention: The Centers for Population Health and Health Disparities experience Sarah Gehlert
14:00:00 Team science and transdisciplinarity in cancer prevention research across the life cycle: The Breast Cancer and the Environment Research Program experience Robert A. Hiatt
14:15:00 The NCI perspective on the significance and importance of team science and transdisciplinarity for cancer prevention research: The TTURC experience Glen Morgan
14:40:00 Educational Sessions - 5: Clinical Trial Novel Design: Retooling Drugs for Prevention Andrea Decensi
14:45:00 Common drugs associated with reduced cancer risk Gad Rennert
15:00:00 Efficient trial designs and suitable cohorts to assess preventive agents Jack Cuzick
15:10:00 Presurgical models to effectively screen preventive agents Andrea Decensi
15:15:00 Educational Sessions - 6: The Indigenous Gut Microbiota in Colon Cancer
15:20:00 Understanding the structure and function of the gut microbiota
15:40:00 Colonic bacteria, inflammation, and colon cancer Cynthia L. Sears
16:00:00 The microbiota and development of colitis-associated colorectal cancer Christian Jobin
16:30:00 Special Session: View From the NCI Peter Greenwald, Robert T. Croyle
18:00:00 Opening Plenary Session
18:05:00 Keynote Address Elizabeth Blackburn
18:30:00 Distinguished Lecture on Targets for Cancer Prevention Inflammation and cancer: Interweaving microRNA, innate immune, and p53 pathways Curtis C. Harris
19:30:00 Opening Reception
Monday, November 8, 2010
07:00:00 Breakfast Session Roundtables
08:30:00 Plenary Session 1: Personalized Prevention Scott M Lippman
08:35:00 Proximity of personalized risk and predictive markers to the clinic Scott M Lippman
08:45:00 Pharmacogenetics of nicotine dependence treatment: Implications for targeted therapy Caryn Lerman
09:00:00 ODC genotype as prognostic and predictive factors in colorectal carcinogenesis and prevention Eugene W. Gerner
09:20:00 Selenium, genes, and cancer prevention Jing Ma
10:15:00 Concurrent Sessions 1 : Infections Douglas R LOWY
10:20:00 Current and future HPV vaccines Douglas R LOWY
10:30:00 Immunotherapy of established lesions caused by high-risk HPV Cornelis J.M. Melief
10:40:00 HBV vaccination to prevent hepatocellular carcinoma Mei-Hwei Chang
10:45:00 Concurrent Sessions 2 : Recently Completed Developmental Trials in Chemoprevention Howard H. Bailey
10:50:00 Randomized, placebo-controlled, double-blind Phase IIB trial of Bowman-Birk inhibitor concentrate in patients with oral leukoplakia Frank L. Meyskens
11:00:00 Randomized phase II trial of genistein in patients with localized prostate cancer Dr. Raymond Bergan
11:10:00 Phase 0 trial of SR13668, an orally active AKT inhibitor Joel M. Reid
11:20:00 Topical chemoprevention of skin cancers Joanne M. Jeter
11:30:00 Discussion Howard H. Bailey
11:35:00 Concurrent Sessions -3 : Interventions to Reduce Cancer Health Disparities Electra D. Paskett
11:40:00 Community-based intervention to reduce liver cancer disparities in Asian Americans: A cluster randomized trial Roshan Bastani
11:45:00 Randomized trial of a lay health advisor and computer intervention to increase mammography screening in African American women Electra D. Paskett
11:50:00 Improving follow-up to abnormal breast cancer screening in an urban population: A patient navigation intervention Tracy Battaglia
11:55:00 Short talk from proffered abstracts
12:00:00 Lunch on own
13:15:00 Concurrent Sessions - 4 : Molecular Targets for Cancer Prevention Eva Szabo
13:20:00 PPARgamma in aerodigestive cancer prevention Eva Szabo
13:30:00 Strategies to target the insulin/IGF-I receptor family for cancer prevention Michael Pollak
13:40:00 PI3K as a target for lung cancer chemoprevention Andrea H. Bild
13:45:00 Concurrent Sessions - 5 : Prostate Cancer Dr. Raymond Bergan
13:50:00 Early molecular changes in prostate carcinogenesis William G. Nelson
14:00:00 The role of estrogen in prostate cancer development and prevention Shuk-Mei Ho
14:10:00 Decision making in prostate cancer screening Kathryn L. Taylor
14:15:00 Concurrent Sessions - 6 : Individualized Diet and Cancer Prevention Johanna W. Lampe
14:20:00 Soy foods and cancer risk: How does the relation vary in individuals with different ethnicity, diet, and lifestyle? Gertraud Maskarinec
14:30:00 Green tea and pomegranate: The role of metabolites in chemoprevention Susanne M. Henning
14:40:00 Vegetable constituents and biotransformation enzymes: The effect of genetic variation on response Johanna W. Lampe
15:15:00 Plenary Session 2: New Approaches to Identifying High-risk Populations Avrum E. Spira
15:20:00 Identifying the smoker at risk for lung cancer Avrum E. Spira
15:30:00 Cancer risk: Stratification through biophotonic detection of field carcinogenesis Hemant K. Roy
15:40:00 Somatic evolution and neoplastic progression in Barrett’s esophagus: Lessons in space and time Brian J. Reid
15:50:00 New insights into genetic susceptibility to breast cancer Douglas Easton
17:15:00 AACR-Prevent Cancer Foundation Award for Excellence in Cancer Prevention Research Lecture
18:15:00 Poster Session A
Tuesday, November 9, 2010
07:00:00 Report on AACR-NCI Think Tank: Charting the Future of Cancer Prevention Raymond N DuBois
08:00:00 Plenary Session 3: Bioenergetics and Cancer John A. , Milner
08:05:00 Introduction John A. , Milner
08:15:00 Exercise, BMI, and cancer Anne McTiernan
08:30:00 Nrf2 and cancer protection Rafael de Cabo
08:45:00 Cancer cure and prevention: Lessons learned from a small but highly effective agent Peter Pedersen
09:00:00 Obesity and mTOR signaling George Thomas
10:15:00 Concurrent Sessions 7 : Lung Cancer Prevention Jenny T. Mao
10:20:00 Natural history of bronchial preneoplasia Stephen Lam
10:30:00 Neutrophil elastase links lung cancer and COPD McGarry Houghton
10:40:00 Efficient designs for lung cancer prevention trials: Lessons learned and moving forward J. Jack Lee
10:50:00 Recent studies on mechanisms and prevention of tobacco-induced cancer Stephen S Hecht
11:00:00 Concurrent Sessions 8 : Novel Targets and Strategies for Breast Cancer Prevention Powel H. Brown
11:10:00 Implications of the cancer stem cell hypothesis for breast cancer prevention Max S Wicha
11:20:00 Breast cancer prevention: Predictors and outcomes of patient decision making Suzanne C. O'Neill
11:30:00 PARP inhibitors: Early promise in breast and ovarian cancer prevention Judy E Garber
11:40:00 Concurrent Sessions 9 : Molecular Approaches to Early Detection Samir Hanash
11:45:00 Autoantibodies and early detection of lung cancer Samir Hanash
11:50:00 Novel strategies for the early detection of solid cancers through vascular biomarkers George Coukos
11:55:00 Molecular approaches to early detection of pancreatic cancer Caroline Hollingsworth
12:00:00 Lunch on own
13:15:00 Concurrent Sessions - 10 : The Microenvironment Thea D. Tlsty
13:20:00 Stromal-epithelial interactions in early carcinogenesis Thea D. Tlsty
13:30:00 Stromal signals from the involuting microenvironment that are important in postpartum breast cancer Pepper J Schedin
13:40:00 Profiling of tumors to identify factors that contribute to cancer health disparities Stefan Ambs
13:45:00 Concurrent Sessions 11 : Advances in the Genetics and Treatment of Cancer Susceptibility Syndromes Katherine L. Nathanson
13:50:00 Pheochromocytoma and paraganglioma Katherine L. Nathanson
14:00:00 Clinical trials in neurofibromatosis 1 and 2 Scott Plotkin
14:10:00 Chemoprevention in Lynch syndrome Sir John Burn
14:15:00 Concurrent Sessions 12 : Inflammation and Cancer Prevention Andrew J. Dannenberg
14:20:00 The prostaglandin-aromatase connection: Implications for breast carcinogenesis Andrew J. Dannenberg
14:30:00 The inflammation-EMT-cancer initiating cell axis in the pathogenesis of lung cancer: Breaking ground in the pursuit of targeted chemoprevention Steven Dubinett
14:40:00 The role of inflammation and stromal cells in gastrointestinal cancers Timothy C. Wang
15:15:00 Plenary Session 4: Understanding Neoplastic Progression: Questions and Controversies Carlo C Maley
15:20:00 Evolutionary concepts of cancer Carlo C Maley
15:45:00 Cancer stem cells? Simon Tavare
16:15:00 Title to be announced Alfonso Bellacosa
16:45:00 Why do benign growths so often progress to malignant cancers? John W. Pepper
17:15:00 Poster Session B
Wednesday, November 10, 2010
07:00:00 Breakfast Session Roundtables
08:00:00 Plenary Session 5: Bringing Prevention and Early Detection to the Public: A Global Perspective Michael J. Thun,
08:05:00 Introduction and overview of the global burden of cancer Michael J. Thun,
08:30:00 From basic science to public health: The Canadian approach to oral leukoplakia Miriam P. Rosin
09:00:00 The Australian skin cancer prevention experience: Lessons learned and global challenges ahead Craig Sinclair
10:15:00 Concurrent Sessions - 13 : Colon Cancer Prevention Paul J. Limburg
10:20:00 Immunotherapy for prevention of colorectal cancer Robert E. Schoen
10:30:00 Stool DNA testing to screen colorectal and other aerodigestive cancers David A. Ahlquist
10:40:00 HDAC inhibitors in colorectal cancer chemoprevention Roderick Dashwood
10:50:00 Concurrent Sessions 14 : Head and Neck Cancer Prevention Mary E. Reid
10:55:00 Motivating individual behavior change through theory-driven community engagement Henrietta L. Logan
11:15:00 Implications of fluorescent screening for detection of premalignancy and cancer Mary E. Reid
11:30:00 Identifying the premalignant lesion at high risk for progression to cancer Li Mao
11:40:00 Concurrent Sessions 15 : Communicating Cancer Risks: High-Risk Populations, the Public, and Physician Communication Mary B. Daly
11:45:00 Communicating cancer risk to high-risk patients and their families Mary B. Daly
11:50:00 The importance of form, content, and context in the design and effectiveness of risk communication methods James P Dolan
11:55:00 Making data talk: Communicating science to lay audiences Bradford W. Hesse
12:00:00 Departure
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