3D Tissue Models
Pathogenesis of Influenza: Virus-Host Interactions (E3)
Sheraton Hong Kong Hotel & Towers
20 Nathan Road Kowloon, Hong Kong China
Kowloon, Hong Kong

     *  Abstract Deadline:
       21st January 2011

     *  Registration Deadline:
       22nd March 2011


     *  Sir John J. Skehel, MRC National Institute of Medical Research,
       United Kingdom

     *  Robert G. Webster, St. Jude Children’s Research Hospital, USA

     *  Peter C. Doherty, University of Melbourne, Australia

     *  Ron A.M. Fouchier, Erasmus Medical Center Rotterdam, Netherlands

     *  Yoshihiro Kawaoka, University of Tokyo, Japan

     *  Yi Guan, Hong Kong University, China

     *  Gillian M. Air, University of Oklahoma Health Sciences Center,

     *  John Nicholls, University of Hong Kong, China

     *  Ram Sasisekharan, Massachusetts Institute of Technology, USA

     *  Speaker to be Announced,

     *  Speaker to be Announced,

     *  Jeffery K. Taubenberger, National Institute of Allergy and
       Infectious Diseases, National Institutes of Health, USA

     *  Nadia Naffakh?, Institut Pasteur, France

     *  Malik Peiris, University of Hong Kong, China

     *  Short Talks to be Chosen from Abstracts, ,

     *  Andrew S. Pekosz, Johns Hopkins University, USA

     *  Jacqueline M. Katz, Centers for Disease Control and Prevention,

     *  Kanta Subbarao, NIAID , National Institutes of Health, USA

     *  Caetano Reis e Sousa, Cancer Research UK, London Research
       Institute, United Kingdom

     *  Siamon Gordon, University of Oxford, United Kingdom

     *  Jenny P. Ting, University of North Carolina at Chapel Hill, USA

     *  Tadatsugu Taniguchi, University of Tokyo, Japan

     *  Tao Dong, Institute of Molecular Medicine, United Kingdom

     *  Jack R. Bennink, National Institutes of Health, USA

     *  Ronald N. Germain, NIAID , National Institutes of Health, USA

     *  Sabra Klein, Johns Hopkins University, USA

     *  Adolfo Garcia-Sastre, Mount Sinai School of Medicine, USA

     *  Tracy Hussell, Imperial College London, United Kingdom

     *  Jeffrey A. Whitsett, Cincinnati Children’s Hospital Medical
       Center, USA

     *  Michael Matthay?, University of California, San Francisco, USA

     *  Short Talks to be Chosen from Abstracts, ,

     *  Aviv Regev, Massachusetts Institute of Technology, USA

     *  Philip Dormitzer, Novartis Vaccines, USA

     *  Stephan Ludwig, University of Münster, Germany

   The mechanisms underlying the pathogenesis of influenza remain
   controversial. The direct cytopathic effects of viral replication,
   tissue tropism of the virus, viral-bacterial synergy, as well as
   innate host responses are inextricably linked and play roles to
   varying degrees in

Schedule of Presentations:

Monday, May 23, 2011
15:00:00 Registration
18:15:00 Refreshments
19:30:00 Keynote Session
20:00:00 Structure Function of HA John J. Skehel
20:30:00 The Ecology of Influenza Viruses Robert Webster
21:30:00 T Cells Peter Doherty
Tuesday, May 24, 2011
08:00:00 Breakfast
08:05:00 Poster Setup
09:00:00 Virology
09:30:00 Viral Virulence Ron A.M. Fouchier
10:20:00 Coffee Break
10:45:00 Influenza Pathogenesis Yoshihiro Kawaoka
11:15:00 The Emergence and Development of H1N1/2009 Pandemic Influenza Virus Yi Guan
11:35:00 Influenza Ribonucleoproteins - Host Cell Interactions Nadia Naffakh
12:00:00 Poster Viewing
12:00:00 Lunch
12:00:00 Poster Session 1
14:00:00 Coffee Available
14:30:00 Virus Receptors | Glycans | Structure
14:35:00 Receptors in the Human Respiratory Tract - Making and Breaking the links John Nicholls
15:00:00 Glycans and HA Ram Sasisekharan
15:30:00 New Insights into Broad Neutralization of Influenza Virus and Implications for a Universal Flu Vaccine Ian A. Wilson
16:30:00 Binding and Cleavage of Sialylated Glycans by H3N2 and H1N1 Influenza Viruses Gillian M. Air
Wednesday, May 25, 2011
08:00:00 Breakfast
09:00:00 Human Disease, Lung Injury and Human-Cell Experimental Models
09:05:00 Influenza Pathogenesis in Humans | Revisited Sherif R. Zaki
09:30:00 Lung Injury and ARDS Arthur Slutsky
10:00:00 Toward the Design of Universal Glycoprotein Vaccines against Influenza and other Viral Diseases Chi-Huey Wong
10:20:00 Coffee Break
11:00:00 Human ex-vivo and in-vitro Experimental Models for Studying Influenza Pathogenesis Malik Peiris
12:00:00 Lunch
13:00:00 Workshop 1 | Pathogen-Host Interaction | Short Talks to be Chosen from Abstracts
14:00:00 Coffee Available
14:30:00 Experimental Models
14:35:00 Influenza A Virus Infection of Primary, Differentiated Respiratory Epithelial Cell Cultures Andrew S. Pekosz
15:00:00 Small Animal Models for the Study of Influenza Virus Pathogenesis
16:00:00 Replication of Influenza Viruses in Non-Human Primates Kanta Subbarao
16:45:00 European Research Activities on Influenza
Thursday, May 26, 2011
08:00:00 Breakfast
08:05:00 Poster Setup
09:00:00 Immunity (Myeloid Cells)
09:05:00 Mechanisms of RNA Recognition through RIG-I and TLR7 Gunther Hartmann
09:30:00 Effect of IL-4 on Influenza Replication and Cytokine Expression in Primary Human Monocyte-Derived Macrophages in vitro Siamon Gordon
10:20:00 Coffee Break
10:45:00 NLRs and viral infection Jenny P. Ting
11:00:00 Endo- and Exogenous Adjuvant for Influenza Vaccination Ken Ishii
12:00:00 Lunch
12:05:00 Poster Viewing
12:10:00 Poster Session 2
14:00:00 Coffee Available
14:30:00 Immunity, Systems Biology, Gender and Susceptibility
14:35:00 Antigen Specific T Cells in Human Influenza A Virus Infection Tao Dong
15:00:00 Antigenic Drift: Mechanisms of Influenza A Virus Hemagglutinin Immune Escape Jack R. Bennink
15:30:00 A Systems Approach to Influenza Infection and Vaccine Responses Ronald N. Germain
16:00:00 Sex Differences in Response to Influenza Virus Infection and Vaccination Sabra Klein
Friday, May 27, 2011
08:00:00 Breakfast
09:00:00 Pathogenesis | Lung Injury
09:05:00 In vivo Dynamics of Influenza Virus Infection Adolfo Garcia-Sastre
09:30:00 Influenza-Induced Immunological Alterations in the Respiratory Tract Tracy Hussell
10:20:00 Coffee Break
10:45:00 A Transcriptional Network Linking Respiratory Epithelial Cell Differentiation and Innate Immunity Jeffrey A. Whitsett
11:45:00 Short Talks to be Chosen from Abstracts
12:00:00 Lunch
13:00:00 Workshop 2 | Modulation of Infection | Short Talks to be Chosen from Abstracts
14:00:00 Coffee Available
14:30:00 Interventions
14:35:00 Host-Influenza Interactions Aviv Regev
15:00:00 Advances in Vaccines Against Seasonal and Pandemic Influenza Philip R. Dormitzer
16:00:00 Intracellular Signal Transduction and Influenza Virus Infection – Identifying Novel Targets for Antiviral Therapy Stephan Ludwig
18:00:00 Social Hour w/ Lite Bites
19:00:00 Entertainment
Saturday, May 28, 2011
09:00:00 Departure
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