5th Drug Discovery for Neurodegeneration: An Intensive Course for Translating Research into Drugs
600 F Street
San Diego, California 92101

     *  Registration Deadline:
       17th December 2010


   listed at the conference website

   The purpose of the conference is to advance drug discovery for
   neurodegenerative diseases by

   600 F Street, San Diego, CA, 92101, United States

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Schedule of Presentations:

Sunday, February 6, 2011
14:30:00 Registration Exhibitor & Poster Setup
16:30:00 Welcome & Opening Remarks: Overview of Drug Discovery for Neurodegenerative Diseases Howard Fillit
16:50:00 PLENARY: The Neurovascular Unit: Biology of Blood Brain Barrier in Neurodegenerative Diseases Berislav Zlokovic
17:20:00 Q&A
17:30:00 Closing Remarks Howard Fillit
17:35:00 Welcoming Reception
Monday, February 7, 2011
08:00:00 Continental Breakfast
08:30:00 Welcome & Opening Remarks Howard Fillit
08:35:00 Overview: Medicinal Chemistry Rules of Thumb, Myths and Realities in CNS Drug Discovery D Martin Watterson
08:55:00 Q&A
09:05:00 Designing Small Molecules with Increased Potential for CNS Penetration Laura Chico
09:45:00 Synthetic Chemistry Essentials for Biologists Heather Behanna
10:25:00 Structure Assisted Ligand Design Vicki Nienaber
10:55:00 Q&A
11:35:00 Session Overview Kurt Brunden
11:40:00 Basics of High Throughput Screening (HTS) J Inglese
11:40:00 Basics of High Throughput Screening (HTS) J Inglese
12:00:00 Q& A
12:10:00 After HTS: Solubility, Selectivity, Safety and Stability in Addition to Potency Kurt Brunden
12:30:00 Q&A
12:40:00 Importance of Toxicology John E. Sagartz
13:05:00 Q&A
14:25:00 Session Overview Edward Spack
14:30:00 What Makes a Clinical Candidate? William Potter
14:50:00 Q&A
15:05:00 Requirements for an IND Edward Spack
15:20:00 Q&A
16:00:00 The Limitations and Value of Animal Models for Neurodegenerative Disease Steve Perrin
16:30:00 Regulatory Requirements in Preparing for Clinical Trials Eric Bastings
17:00:00 Closing Remarks Howard Fillit
Tuesday, February 8, 2011
06:00:00 Natural Products as Drug Starting Points Frank Koehn
07:30:00 Continental Breakfast
08:00:00 Welcome & Opening Remarks: Overview of Drug Discovery for Neurodegenerative Diseases Neil Buckholtz
08:05:00 Session Overview Diana Shineman
08:30:00 Q&A
08:40:00 Unique Challenges for Biologics Joao Siffert
09:00:00 Q&A
09:10:00 The Road to Repurposing a Drug: Isradipine D. James Surmeier
09:30:00 Q&A
10:10:00 Session Overview Brian Fiske
10:15:00 Neurotrophic Factor Mimetics: Target Validation to Lead Optimization Frank Longo
10:35:00 Q&A
10:45:00 Development of Tysabri for Multiple Sclerosis Ted Yednock
11:05:00 Q&A
11:15:00 Novel Ways to Reduce Protein Aggregation Alan Snow
11:35:00 Q&A
12:45:00 Session Overview Kathleen Denis
12:50:00 Working Effectively with Your TTO: Technology Evaluation Process and IP Protection Kathleen Denis
13:20:00 Q&A
13:30:00 Creating Mutually Beneficial Relationships with Industry: Needs, Wants and Paperwork Louis Berneman
14:45:00 Q&A
14:55:00 Should You Start a Biotechnology Company? John S. Swartley
15:15:00 Q&A
15:20:00 BREAK
15:35:00 Session Overview Suzana Petanceska
15:40:00 Academic Models of Drug Discovery Services & Utilizing CROs Marcie Glicksman
16:00:00 Q&A
16:10:00 Resources at the National Institute of Health William Matthew, Neil Buckholtz
16:40:00 Closing Remarks Howard Fillit
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